The Characteristics of Regional Bone Quality in the Cervical Vertebrae Considering BMD

Data of CT images and the femoral neck BMD were obtained from 99 patients who underwent the cervical CT and BMD simultaneously (the gap of both studies was within 6 months) from April 2009 to December 2014. There were 52 females and 47 males. The mean age was 63.7 year (female: 63.4 years, male: 64.1; range 32-86 years). The patient was excluded who had any destructive pathology or severe spondylosis in the cervical pedicle and the cervical lateral mass. Patients were divided into three groups according to femoral neck BMD (Group A, T-score ≥-1; Group B, -2.5<T-score<-1.0; Group C, T-score≤-2.5). Group A had normal BMD patients, Group B had lower normal patients including osteopenic patients and Group C presented osteoporotic patients. The mean HU numbers of cortical bone area in the vertebral canal (cHU, the medial wall of the lateral mass), the posterior wall of transverse foramen (fHU), the medial (mHU), lateral wall (lHU) and trabecular area of pedicle (pHU) were measured on the axial CT images in clinical images.

Study Overview

• Status: Completed
• Conditions: Cortical Bone Thickness
• Intervention / Treatment: Other: Cortical Bone thickness and Hounsfield unit (HU) numbers

• Study Type: Observational
• Enrollment (Actual): 99

Contacts and Locations

Study Locations

• Korea, Republic of
  • Kangwondo
    • Gangneung, Kangwondo, Korea, Republic of, 25440
      • Moon-Kyu Kim

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 25 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Data of CT images and the femoral neck BMD were obtained from 99 patients who underwent the cervical CT and BMD simultaneously (the gap of both studies was within 6 months)

Description

Inclusion Criteria:

• Patients who underwent the cervical CT and BMD simultaneously (the gap of both studies was within 6 months)

Exclusion Criteria:

• Who had any destructive pathology or severe spondylosis in the cervical pedicle and the cervical lateral mass.

Study Plan

How is the study designed?

Number of groups / cohorts

3

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Group A; T-score ≥-1	Other: Cortical Bone thickness and Hounsfield unit (HU) numbers; Cortical Bone thickness and Hounsfield unit (HU) numbers considering BMD
Group B; -2.5<T-score<-1.0	Other: Cortical Bone thickness and Hounsfield unit (HU) numbers; Cortical Bone thickness and Hounsfield unit (HU) numbers considering BMD
Group C; T-score≤-2.5	Other: Cortical Bone thickness and Hounsfield unit (HU) numbers; Cortical Bone thickness and Hounsfield unit (HU) numbers considering BMD

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Cortical bone Thickness	two weeks
HU number	two weeks

Collaborators and Investigators

• Sponsor: Gangneung Asan Hospital
• Collaborators: The Catholic University of Korea

Study record dates

Study Major Dates

• Study Start: April 1, 2009
• Primary Completion (Actual): December 1, 2014
• Study Completion (Actual): August 1, 2016

Study Registration Dates

• First Submitted: December 9, 2016
• First Submitted That Met QC Criteria: December 14, 2016
• First Posted (Estimate): December 16, 2016

Study Record Updates

• Last Update Posted (Estimate): December 16, 2016
• Last Update Submitted That Met QC Criteria: December 14, 2016
• Last Verified: December 1, 2016

More Information

Terms related to this study

• Other Study ID Numbers: Anatomy C-Spine

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED