The Ohio State University Dermatology Biorepository

This study will create and extend a source of clinical specimens for the future study of inflammatory skin disorders.

Study Overview

• Status: Recruiting
• Conditions: Hidradenitis Suppurativa

Detailed Description

A variety of molecular techniques can be used to investigate diseases by analyzing protein, DNA, and RNA. Flow cytometry, Polymerase chain reaction (PCR), histology and immunohistochemistry are assays which can identify specific cell populations and provide valuable information regarding the pathologic characteristics of those populations. Flow cytometry analyzes the surface markers of cells. Histology and immunohistochemistry further characterize surface and cellular molecules and aid in the diagnosis of certain skin diseases. Gene expression profiling allows investigators to examine the genes detectable to determine the function of the cells involved, and PCR techniques are useful for the diagnosis of certain conditions and for DNA analysis.

By procuring blood, skin tissue, and swab samples from patients with and without neoplastic and inflammatory skin disorders at the time of their appointments, the hypothesize that future translational research can be conducted on such specimens using the aforementioned techniques to further understand disease mechanisms in cutaneous disorders, and to potentially discover defective function and genetic mutations within cells from patients with neoplastic and inflammatory skin disorders. By establishing a tissue bank, we aim to lay the foundation for future work that will improve our understanding of the biology and natural history of neoplastic and inflammatory cutaneous diseases.

• Study Type: Observational
• Enrollment (Estimated): 175

Contacts and Locations

• Study Contact: Name: Alison Rocchi; Phone Number: 614-685-0251; Email: Alison.Wandling@osumc.edu
• Study Contact Backup: Name: Kristina Susi; Phone Number: 614-814-1277; Email: Kristina.Susi@osumc.edu

Study Locations

• United States
  • Ohio
    • Columbus, Ohio, United States, 43215
      • Recruiting
      • OSU Dermatology West
      • Principal Investigator: Benjamin Kaffenberger, MD
      • Contact: Alison Rocchi; Phone Number: 614-685-0251; Email: Alison.Wandling@osumc.edu
      • Contact: Kristina Susi; Phone Number: 614-814-1277; Email: Kristina.Susi@osumc.edu

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Probability Sample

Study Population

Any person that meets the inclusion/exclusion criteria

Description

Inclusion Criteria:

• Seen by an Ohio State University (OSU) Dermatology provider on the main University Hospital campus, including the James Cancer Hospital, OSU Dermatology East, OSU Dermatology at the Ohio State Eye and Ear Institute, Martha Morehouse Medical Pavilion, and OSU Dermatology at Upper Arlington after the date of approval of this protocol
• Ability to provide informed consent, or parent or legal guardian capable of providing consent for child or mentally handicapped individuals
• Willingness to participate in a research study.

Exclusion Criteria:

• Inability to provide informed consent

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Source of clinical specimens for the future study of neoplastic and inflammatory skin disorders	5 years

Collaborators and Investigators

• Sponsor: Ohio State University
• Investigators: Principal Investigator: Benjamin Kaffenberger, MD, Dermatologist

Study record dates

Study Major Dates

• Study Start (Actual): April 19, 2017
• Primary Completion (Estimated): December 31, 2030
• Study Completion (Estimated): December 31, 2030

Study Registration Dates

• First Submitted: May 5, 2017
• First Submitted That Met QC Criteria: May 9, 2017
• First Posted (Actual): May 10, 2017

Study Record Updates

• Last Update Posted (Actual): February 27, 2026
• Last Update Submitted That Met QC Criteria: February 24, 2026
• Last Verified: February 1, 2026

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Infections; Skin Diseases; Bacterial Infections; Bacterial Infections and Mycoses; Sweat Gland Diseases; Skin Diseases, Bacterial; Skin Diseases, Infectious; Suppuration; Hidradenitis; Skin and Connective Tissue Diseases; Hidradenitis Suppurativa
• Other Study ID Numbers: 2010H0331

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No