General Anesthetic Mode and Postoperative Complications

November 3, 2017 updated by: Yan Zhou, MD, Peking University First Hospital

Relationship Between General Anesthetic Mode and Postoperative Severe Cardiovascular and Cerebrovascular Complications: a Retrospective Cohort Study

The relationship between anesthetic medication and postoperative major cardiac and cerebral complications will be studied using logistic regression model.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

The study group try to find out if there is a connection between the use of different anesthetic methods with different narcotic drugs and postoperative major cardiac and cerebral complications.

Study Type

Observational

Enrollment (Actual)

50000

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 100 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

patients for non-cardiac surgery under general anesthesia

Description

Inclusion Criteria:

  • non-cardiac surgery, with age> = 18 years old, ASA grade I-IV, under general anesthesia

Exclusion Criteria:

  • non-general anesthesia, without the use of target-controlled infusion of remifentanil or sufentanil, absence of intraoperative or perioperative information.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Retrospective

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
non-MACE
patients without major postoperative cardiac or cerebral complications
Combination product: inhalation or propofol ,epidural or general anesthesia, remifentanil or sufentanil
Different combination of opioids and anesthetics
MACE
patients with major postoperative cardiac or cerebral complications
Combination product: inhalation or propofol ,epidural or general anesthesia, remifentanil or sufentanil
Different combination of opioids and anesthetics

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Major cardiac complication
Time Frame: 90 days after surgery
major cardiac event
90 days after surgery

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Peking University First Hospital

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

December 31, 2016

Primary Completion (Actual)

August 1, 2017

Study Completion (Actual)

October 10, 2017

Study Registration Dates

First Submitted

October 30, 2017

First Submitted That Met QC Criteria

November 3, 2017

First Posted (Actual)

November 7, 2017

Study Record Updates

Last Update Posted (Actual)

November 7, 2017

Last Update Submitted That Met QC Criteria

November 3, 2017

Last Verified

November 1, 2017

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • GATCIMACE

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

Undecided

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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