A Registered Cohort Study on Cerebellar Ataxia in the Organization in South-East China for Cerebellar Ataxia Research (OSCCAR)

A Registered Cohort Study on Cerebellar Ataxia

Cerebellar ataxia is a form of ataxia originating in the cerebellum. Cerebellar ataxia can occur as a result of many diseases and may present with symptoms of an inability to coordinate balance, gait, extremity and eye movements. To understand the clinical and genetic characteristics of cerebellar ataxia, we establish a registered cohort to follow up Chinese patients with cerebellar ataxia.

Study Overview

• Status: Recruiting
• Conditions: Cerebellar Ataxia
• Intervention / Treatment: Other: No intervention

• Study Type: Observational
• Enrollment (Estimated): 1500

Contacts and Locations

• Study Contact: Name: Yi Lin, MD.Phd; Phone Number: +8613615039153; Email: linyi7811@163.com
• Study Contact Backup: Name: Shi-Rui Gan, MD.Phd; Phone Number: +8613850172725; Email: ganshirui@fjmu.edu.cn

Study Locations

• China
  • Fujian
    • Fuzhou, Fujian, China, 350005
      • Recruiting
      • Department of Neurology ,First Affiliated Hospital Fujian Medical University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult; Older Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Non-Probability Sample

Study Population

Patients with cerebellar ataxia who are diagnosed by tow neurologists in the Organization in South-East China for Cerebellar Ataxia Research (OSCCAR) from the First Affiliated Hospital of Fujian Medical University.

Description

Inclusion Criteria:

• Patients with cerebellar ataxia based on the diagnoses of tow neurologists
• Relatives of patients with cerebellar ataxia
• Unrelated healthy controls
• Participants or legal guardian(s) willing and able to complete the informed consent process

Exclusion Criteria:

• Participants are unable to comply with trial procedures and visit schedule

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
The incidence of hereditary cerebellar ataxia	Look for the causative gene in the patient with cerebellar ataxia	Up to 20years

Collaborators and Investigators

• Sponsor: Ning Wang, MD., PhD.

Study record dates

Study Major Dates

• Study Start (Actual): July 1, 2019
• Primary Completion (Estimated): December 1, 2039
• Study Completion (Estimated): December 1, 2059

Study Registration Dates

• First Submitted: July 4, 2019
• First Submitted That Met QC Criteria: July 4, 2019
• First Posted (Actual): July 8, 2019

Study Record Updates

• Last Update Posted (Actual): July 12, 2023
• Last Update Submitted That Met QC Criteria: July 11, 2023
• Last Verified: July 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurologic Manifestations; Dyskinesias; Cerebellar Diseases; Ataxia; Cerebellar Ataxia
• Other Study ID Numbers: MRCTA,ECFAH of FMU[2019]195

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No