Characterization of Hamstring and Quadriceps Neuromuscular Fatigue After Soccer Game (QIF)

April 19, 2022 updated by: University Hospital, Strasbourg, France

Characterization of Hamstring and Quadriceps Neuromuscular Fatigue After Different Modality of Training in Soccer Players

This is a monocentric study comparing hamstring and quadriceps neuromuscular fatigue after simulated soccer game, anaerobic and aerobic training sessions. The purpose of this study was:

  1. To quantify the decrease of isometric force immediately after a simulate soccer game.
  2. To characterize peripheral and central fatigue between hamstring and quadriceps muscles and described the kinetics of recovery after specific tasks of soccer training.
  3. To compare the level neuromuscular fatigue induced by anaerobic and aerobic training.
  4. To highlight correlation between neuromuscular fatigue and performance markers.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Anticipated)

15

Phase

  • Phase 2

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

16 years to 40 years (ADULT, CHILD)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

Male

Description

Inclusion Criteria:

  • male
  • age limits: minimum: 16 ; maximum: 40 years old
  • to be a soccer player, licensed to the French Football Federation
  • affiliation to the social health insurance scheme
  • signing an informed consent form

Exclusion Criteria:

  • impossibility to give the subject enlightened information (subject in emergency situation, difficulties in understanding the study, …)
  • subject under the protection of justice
  • subject under guardianship or curatorship
  • lower limbs musculotendinous or articular problems
  • smoker or having been a smoker in the last 5 years
  • subject wearing a pacemaker
  • drug treatment in progress and impossibility to stop it within 7 days before the beginning of the study.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: BASIC_SCIENCE
  • Allocation: NA
  • Interventional Model: SINGLE_GROUP
  • Masking: NONE

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
EXPERIMENTAL: Physical exercices arm
three randomizations will be used to determine the order of the tests that will be proposed to the subjects: on the one hand for the exercise modalities (match, anaerobic, aerobic) and, on the other hand, for the exercise modalities included in the anaerobic and aerobic exercise families: Anaerobic agility / anaerobic - linear sprints Aerobic - shuttle / aerobic - linear
Other: Physical exercices

surface EMG: surface electrodes will be positioned on the muscles to evaluate the level of muscle activation

non invasive muscular neurostimulations : application of a percutaneous electrical stimulation of the motor nerve of the considered muscle and a direct electrical stimulation of the muscle

Other Names:
  • Non invasive muscular neurostimulations
  • Surface EMG

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Difference in maximal isometric hamstring strength before and immediately after exercise (i.e., pre vs. immediate post exercise) expressed as a percentage (%).
Time Frame: Before and immediately post exercise (i.e., during the first minute after cessation of exercise)
Before and immediately post exercise (i.e., during the first minute after cessation of exercise)

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Relative difference (in %) in maximum isometric hamstring strength before and after exercise (i.e., pre- vs. post-exercise), relative to pre-exercise strength across different test types.
Time Frame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Relative difference (in %) in maximal isometric quadriceps strength before and after exercise (i.e., pre vs. post exercise), related to preexercise strength according to the different types of tests.
Time Frame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Relative difference (%) in maximum isometric hamstring and quadriceps strength for each test type at the different times of interest.
Time Frame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Difference in pre- and post-exercise (i.e., pre- vs. post-exercise) hamstring potentiated jerk amplitude (N) relative to pre-exercise amplitude by event type at different times of interest.
Time Frame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Difference in pre- and post-exercise (i.e., pre- vs. post-exercise) potentiated jerk amplitude (N) of the quadriceps, relative to pre-exercise amplitude, by test type at different times of interest.
Time Frame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Difference in amplitude of the potentiated jerk (N) before and after exercise, related to the preexercise amplitude according to the muscle involved (hamstrings or quadriceps) and the type of test at different times of interest.
Time Frame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Difference in the level of voluntary hamstring activation, expressed in newtons (N), before and after exercise, related to the pre-exercise action level, according to the type of test at different times of interest.
Time Frame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Difference in the level of voluntary quadriceps activation, expressed in newtons (N), before and after exercise, related to the pre-exercise action level, according to the type of test at different times of interest.
Time Frame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Difference in the level of voluntary action before and after exercise, related to the level of action before exercise, according to the muscle involved (hamstrings or quadriceps) and the type of test at different times of interest.
Time Frame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Differences in overall fatigue, peripheral fatigue, and central fatigue of hamstrings versus quadriceps between exercise modalities.
Time Frame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Determine the modalities of exercises which induce the highest level of fatigue and characterize the etiology of neuromuscular fatigue (i.e., peripheral or central) for typical drills performed daily by elite soccer players
Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Ratio (%) of initial to post-exercise values based on field indicators and neuromuscular fatigue.
Time Frame: Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise
Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University Hospital, Strasbourg, France

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (ACTUAL)

November 4, 2021

Primary Completion (ANTICIPATED)

July 1, 2023

Study Completion (ANTICIPATED)

July 1, 2023

Study Registration Dates

First Submitted

June 2, 2021

First Submitted That Met QC Criteria

June 23, 2021

First Posted (ACTUAL)

June 29, 2021

Study Record Updates

Last Update Posted (ACTUAL)

April 27, 2022

Last Update Submitted That Met QC Criteria

April 19, 2022

Last Verified

April 1, 2022

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 8168

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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