Implementation of a Collaborative Care Model to Manage Depression Among Adolescents and Young Adults in HIV Services in Thailand

Implementation of a Collaborative Care Model to Screen and Treat Depression Among Adolescents and Young Adults Ages 15-24 Years Seeking HIV Treatment and Prevention Services in Bangkok, Thailand

This study aims to investigate the acceptability and feasibility of the implementation of a collaborative care model (CCM) to screen and treat depression. This model will includes cognitive behavioral therapy (CBT) and useof a task-shifting model to address depression among adolescents and young adults (AYA) who are seeking HIV treatment and prevention services at a hospital in Bangkok, Thailand. Analyses will be guided by the consolidated framework for implementation research (CFIR), which will include the identification of facilitators and barriers to implementation of this CCM.

In the last 3 years, 10-20% of AYA patients at King Chulalongkorn Memorial Hospital (KCMH) who seek HIV treatment or prevention services suffer from mental health disorders. As a result, CCM integration for depression screening and treatment was implemented at the 'CU Buddy Clinic' KCMH with the ultimate goal of increasing access to and engagement in mental healthcare with a goal to improve the overall quality of life for Thai AYA. This project will inform a future implementation science study that will focus on how the optimization of integrated mental healthcare into routine AYA HIV treatment and prevention services can impact health outcomes for patients, including ART adherence and long-term viral suppression (AYA living with HIV) and HIV acquisition risk behaviors and PrEP adherence (AYA at risk for HIV).

Study Overview

• Status: Completed
• Conditions: Depression; HIV
• Intervention / Treatment: Other: Collaborative Care Model

• Study Type: Observational
• Enrollment (Actual): 32

Contacts and Locations

Study Locations

• Thailand
  • Bangkok, Thailand
    • Chulalongkorn University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: ADULT; OLDER_ADULT; CHILD
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

1. Service users aged 15-24 starting or currently receiving HIV treatment and prevention services, which includes any individual or combination receipt of the following services: ART, PrEP, HIV testing, receipt of condoms, HIV risk counselling
2. Staff providing care at the adolescent HIV treatment and prevention services, with any active patient interface, such as physicians, nurses, peer navigators, psychologists and psychiatrists

Description

AYA patients at the CU Buddy Clinic (for both quantitative and qualitative study)

Inclusion criteria

• Aged 15-24 years of age
• Starting or currently receiving HIV treatment and prevention services, which includes any individual or combination receipt of the following services: ART, PrEP, HIV testing, receipt of condoms, HIV risk counselling
• Thai Nationality

Exclusion criteria

• Individuals with a history of, or are currently receiving, mental healthcare at the CU psychiatric clinic or elsewhere

Service providers at CU Buddy Clinic

Inclusion criteria

• Current staff providing care at the CU Buddy Clinic with any active patient interface, such as physicians, nurses, peer navigators, psychologists and psychiatrists

Exclusion criteria

• Staff with less than 3 months duration of service at the CU Buddy Clinic
• Staff who are not affiliated with the CU Buddy Clinic

Study Plan

How is the study designed?

Design Details

• Observational Models: Other
• Time Perspectives: Cross-Sectional

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Adolescents and Young Adults; Adolescents and Young Adults Seeking HIV Treatment and Prevention	Other: Collaborative Care Model; Use of the collaborative care model to screen and deliver care for depression in adolescents and young adults aged 15-24 years seeking HIV prevention and treatment services
Service Providers; Service Providers for Adolescents and Young Adults Seeking HIV Treatment and Prevention	Other: Collaborative Care Model; Use of the collaborative care model to screen and deliver care for depression in adolescents and young adults aged 15-24 years seeking HIV prevention and treatment services

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Feasibility of using the collaborative care model integration to routine HIV care services	Qualitative assessment - in-depth interviews using semi-structured interview guides individually asking service providers and adolescent service users the feasibility of using the collaborative care model on integration of screening and treatment for depression (including CBT) for standard AYA HIV treatment and prevention services, audio recorded, transcripted and coded for qualitative analysis	1 year
Acceptability of using the collaborative care model integration to routine HIV care services	Qualitative assessment - in-depth interviews using semi-structured interview guides individually asking service providers and adolescent service users the acceptability of using the collaborative care model on integration of screening and treatment for depression (including CBT) for standard AYA HIV treatment and prevention services, audio recorded, transcripted and coded for qualitative analysis	1 year
Facilitators of using the collaborative care model integration to routine HIV care services	Qualitative assessment - in-depth interviews using semi-structured interview guides individually asking service providers and adolescent service users the facilitators of using the collaborative care model on integration of screening and treatment for depression (including CBT) for standard AYA HIV treatment and prevention services, audio recorded, transcripted and coded for qualitative analysis	1 year
Barriers of using the collaborative care model integration to routine HIV care services	Qualitative assessment - in-depth interviews using semi-structured interview guides individually asking service providers and adolescent service users the barriers of using the collaborative care model on integration of screening and treatment for depression (including CBT) for standard AYA HIV treatment and prevention services, audio recorded, transcripted and coded for qualitative analysis	1 year

Collaborators and Investigators

• Sponsor: Chulalongkorn University
• Collaborators: amfAR, The Foundation for AIDS Research

Study record dates

Study Major Dates

• Study Start (ACTUAL): October 1, 2021
• Primary Completion (ACTUAL): February 24, 2022
• Study Completion (ACTUAL): February 24, 2022

Study Registration Dates

• First Submitted: April 20, 2021
• First Submitted That Met QC Criteria: August 8, 2021
• First Posted (ACTUAL): August 16, 2021

Study Record Updates

• Last Update Posted (ESTIMATE): February 9, 2023
• Last Update Submitted That Met QC Criteria: February 7, 2023
• Last Verified: February 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Behavioral Symptoms; Mental Disorders; Mood Disorders; Depression; Depressive Disorder
• Other Study ID Numbers: CHIMERA

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No