Effect of Exercise on Vitamin d in Obese

December 20, 2021 updated by: Lamiaa Elsayyad, Taif University

Effect of Exercise-induced Lipolysis on Vitamin D Status in Obese Children

The aim of the current study was to investigate the effect of exercise-induced lipolysis on vitamin D status in obese children. Two types of exercises that have different effects on lipolysis were used. Lipolysis was assessed via monitoring the level of plasma level of the free fatty acids and glycerol. Vitamin D was assessed through 25 (OH)D plasma levels.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

vitamin D status was monitored through 25 (OH)D levels, and the lipolysis status via the plasma level of the free fatty acids and glycerol immediately after the exercise. All subjects who participated in the study were under supervision for controlling the fat contents and vitamin D in their food for one week prior to the exercise. the subjects fasted eight hours before the exercise. All the exercises were performed between 9 am and 11 am.

Study Type

Interventional

Enrollment (Actual)

30

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Saudi Arabia
    • Mecca
      • Taif, Mecca, Saudi Arabia, 2425
        • College of Applied Medical Sciences

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

7 years to 10 years (CHILD)

Accepts Healthy Volunteers

No

Genders Eligible for Study

Male

Description

Inclusion Criteria:

  • Body mass index percentile equal to or greater than the 95th percentile
  • All did not receive strength or balance training or involvement in competitive sports emphasizing muscular strength.
  • All participants had balance deficiency and mobile flat foot.
  • 25(OH) D was ranged from 10-20ng/ml

Exclusion Criteria:

  • Injury to the lower limb required medical care.
  • Deformity of or surgery in the lower limb.
  • Visual impairment, or neuromuscular disorders.
  • Engagement in obesity treatment programs, three months prior to the study.
  • Epileptic fits
  • Thyroid medications
  • Autoimmune disease
  • Take calcium or vitamin d3 supplements, medications for osteoporosis

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: TREATMENT
  • Allocation: RANDOMIZED
  • Interventional Model: PARALLEL
  • Masking: TRIPLE

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
EXPERIMENTAL: endurance exercise
This group received endurance exercises only.
Other: Endurance exercise
Treadmill training at moderate intensity.
EXPERIMENTAL: resistance exersise plus endurance exersise
This group received resistance exercises followed by endurance exercises.
Other: Endurance exercise
Treadmill training at moderate intensity.
Other: Resistance exersises.
Resistance exercises using the 10 repetition maximum.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Free fatty acids
Time Frame: After 60 min of training
Plasma level of the free fatty acids immediatlly after the exercise.
After 60 min of training
Glycerol
Time Frame: After 60 min of training
Plasma level of glycerol immediatlly after the exercise.
After 60 min of training
Vitamin D
Time Frame: After 60 min of training
Plasma level of 25 (OH) D immediatlly after the exercise.
After 60 min of training

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Taif University

Investigators

  • Study Director: Hatem H Allam, Doctoral, Assisstant professor

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (ACTUAL)

October 6, 2020

Primary Completion (ACTUAL)

February 15, 2021

Study Completion (ACTUAL)

March 25, 2021

Study Registration Dates

First Submitted

September 22, 2021

First Submitted That Met QC Criteria

September 23, 2021

First Posted (ACTUAL)

October 4, 2021

Study Record Updates

Last Update Posted (ACTUAL)

January 11, 2022

Last Update Submitted That Met QC Criteria

December 20, 2021

Last Verified

December 1, 2021

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • HAP-02-T-067 428

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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