Portal Vein Flow Velocity as a Screening Tool for Oesophageal Varices in Cirrhotic Patients (Portalflow)

January 17, 2024 updated by: Peter atef
Portal vein flow velocity as screening tool for prediction of oesophageal varices in cirrhotic patient without upper endoscopy

Study Overview

Status

Recruiting

Conditions

Detailed Description

Portal vein flow velocity as screening tool for prediction of oesophageal varices in cirrhotic patient without upper endoscopy with its high cost & complications Using portal vein flow velocity and the relation between it & presence of oesophageal varices in cirrhotic patient & its efficacy as a primary tool for these cases

Study Type

Observational

Enrollment (Estimated)

75

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

  • Egypt
    • Manfalout
      • Assiut, Manfalout, Egypt, 088
        • Recruiting
        • 43
      • Assiut, Manfalout, Egypt, 088
        • Recruiting
        • Egypt .assiut.manfalout

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

N/A

Sampling Method

Probability Sample

Study Population

Cirrhotic patients with or without E

Description

Inclusion Criteria:

  • cirrhotic patients with oesophageal varices
  • cirrhotic patients without oesophageal varices

Exclusion Criteria:

  • Patients with hepato-cellular carcinomas [HCCs], portal vein thrombosis, hepatic encephalopathy.
  • Patients with positive HCV antibody, but without liver cirrhosis diagnostic criteria

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Case-Crossover
  • Time Perspectives: Cross-Sectional

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Using upper GIT endoscopy to detect the presence or absence of oesophageal varices
Time Frame: 3 years

Non-invasive screening tool for esophageal varices:

Aspartate aminotransferase-to-platelet ratio index (APRI) ... Doppler ultrasound of portal system Elastography both of liver and spleen... -Research outcome measures:

a. Primary (main): Using upper GIT endoscopy to detect the presence or absence of oesophageal varices, and to detect the best and most available non- invasive predictor for it.
3 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Peter atef

Investigators

  • Principal Investigator: Peter At Munir, Master, Assiut University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 4, 2021

Primary Completion (Estimated)

December 2, 2024

Study Completion (Estimated)

December 30, 2024

Study Registration Dates

First Submitted

January 13, 2022

First Submitted That Met QC Criteria

January 27, 2022

First Posted (Actual)

February 8, 2022

Study Record Updates

Last Update Posted (Estimated)

January 18, 2024

Last Update Submitted That Met QC Criteria

January 17, 2024

Last Verified

January 1, 2024

More Information

Terms related to this study

Other Study ID Numbers

  • Patef

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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