Efficacy of Virtual Reality Based Exercise Regimes on Kinesiophobia, Pain and Functional Disability in Patients With Knee Osteoarthritis

Knee Osteoarthritis is one of the most prevalent degenerative conditions in Pakistan. Although a variety of Physical therapy treatments have been proven to be beneficial in patients with early stages of knee Osteoarthritis. However, a few secondary impairments like Kinesiophobia which is the fear of movement have been unaddressed. Usually after conventional physical therapy, patients find immediate or short-term relief and that leads to cessation of follow up sessions. In situations like these, kinesiophobia is the greatest threat to mobility and can eventually effect quality of life by decreasing functional disability.

Study Overview

• Status: Active, not recruiting
• Conditions: Knee Osteoarthristis
• Intervention / Treatment: Procedure: Conventional Physical Therapy for Knee Osteoarthriths; Procedure: Virtual Reality-Based Therapeutic Exercise regimes

• Study Type: Interventional
• Enrollment (Anticipated): 24
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Pakistan
  • Punjab
    • Rawalpindi, Punjab, Pakistan, 46000
      • Foundation University College of Physical Therapy

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 45 years to 65 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Patients with unilateral knee OA involving mediolateral compartment
• Knee OA grade 2
• Aged 40-65 years
• Both Male and Female
• NPRS value greater than

Exclusion Criteria:

• Patients with history of
• History of systemic disorder (e.g., rheumatoid arthritis, ankylosing spondylitis).
• History of malignancy.
• History of trauma.
• Previous knee surgery.
• Congenital musculoskeletal deformity (e.g., scoliosis, kyphosis).
• Patients with history of fracture
• Patients with history of Chondropatella Malacia

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Conventional Physical Therapy Regime for Knee Osteoarthrithis; Pt will receive conventional therapy targeting stretching and stretching of knee musculature in combination with electrotherapy for pain modulation. Frequency : 2-3 times for a duration of 6 weeks Pt will be guided home plan based exercises.	Procedure: Conventional Physical Therapy for Knee Osteoarthriths; Participants of Group A will receive the conventional physical therapy for Knee Osteoarthistis for a duration of 6 weeks atleast 2 times a week
Experimental: Virtual reality Based Therapeutic Exercise Regimes; VR-based therapeutic exercise regimes utilizing Xbox, that focus on different activities like Partial squatting, lunges, side lunge, calf raises, and hamstring curls. Gaming exercises begin will an easy warm up round and get challenging with different rounds of each game as the patient progresses to week 6. Frequency: 2-3 times for a duration for 6 weeks Pt will be guided home plan based exercises	Procedure: Virtual Reality-Based Therapeutic Exercise regimes; Participants of Group B will receive Virtual Reality Based therapeutic exercises on the Xbox. The difficulty level of the games will progess each week. The duration of training will also also progress at treatment week progresses.; Frequency: 2-3 times a week for 6 weeks. Minimum 12 sessions in total.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Kinesiophobia	Kinesiophobia will be measured using the Tampa Scale of Kinesiophobia	6 weeks
Pain intensity	Will be Measured using the Numeric Pain rating scale	6 weeks
Functional Disability	Will be measured using WOMAC Osteoarthritis Index	6 weeks

Collaborators and Investigators

• Sponsor: Foundation University Islamabad

Study record dates

Study Major Dates

• Study Start (Actual): January 1, 2023
• Primary Completion (Anticipated): June 15, 2023
• Study Completion (Anticipated): July 1, 2023

Study Registration Dates

• First Submitted: March 9, 2023
• First Submitted That Met QC Criteria: March 20, 2023
• First Posted (Actual): March 21, 2023

Study Record Updates

• Last Update Posted (Actual): March 21, 2023
• Last Update Submitted That Met QC Criteria: March 20, 2023
• Last Verified: March 1, 2023

More Information

Terms related to this study

• Keywords: Range of Motion, Proprioception
• Additional Relevant MeSH Terms: Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Arthritis; Osteoarthritis; Osteoarthritis, Knee
• Other Study ID Numbers: FUI/CTR/2023/5

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No