- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT05794854
Spot Reduction in Male Adults
March 31, 2023 updated by: Molde University College
The Assessment of Spot Reduction in Adults Males Following Endurance Training
Spot reduction, referring to local body fat reduction, pertains to subcutaneous adipose tissue utilization from specific body parts during exercise.
Its existence has been keenly debated, although generally accepted not to occur during exercise.
However, it is based on not only equivocal data - commonly the training protocol typically applied is based on strength rather than endurance training.
The investigators sought to test this assumption by utilizing endurance based exercise controlling for energy expenditure and using dual x-ray absorptiometric measures to assess body composition before and after training.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Study Type
Interventional
Enrollment (Actual)
16
Phase
- Not Applicable
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
30 years to 60 years (Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
Male
Description
Inclusion Criteria:
- males
- ≥ 30 years old
- classified as overweight (Body mass index ≥ 25 kg ∙ m-2)
- not participating in regular physical training
Exclusion Criteria:
- < 30 years old
- Body mass index < 25 kg ∙ m-2
- participating in regular physical training
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Basic Science
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Single
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: abdominal aerobic endurance exercise
Subjects were combining treadmill running at 70% HRmax (27 minutes) with 4x4minutes (30-40% maximal strength, 1RM) of torso rotation and abdominal crunches (57 minutes), 4 d per wk for 10 weeks
|
Subjects combined treadmill running at 70% HRmax (27 minutes) with 4x4minutes (30-40% maximal strength, 1RM) of torso rotation and abdominal crunches (57 minutes), 4 days per wk for 10 weeks
|
|
Active Comparator: Control group
Subjects performed only treadmill running (45 minutes) at 70% HRmax for 4 d per week for 10 weeks.
|
Subjects performed treadmill running (45 minutes) at 70% HRmax 4 days per week for 10 weeks
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Trunk fat mass change
Time Frame: Change from pre (baseline) to post test (after 10 weeks)
|
Fat mass located in trunk (g) measured by dual-energy x-ray absorptiometry
|
Change from pre (baseline) to post test (after 10 weeks)
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Lower extremity fat mass change
Time Frame: Change from pre (baseline) to post test (after 10 weeks)
|
Fat mass located in lower extremities (g) measured by dual-energy x-ray absorptiometry
|
Change from pre (baseline) to post test (after 10 weeks)
|
|
Upper extremity fat mass change
Time Frame: Change from pre (baseline) to post test (after 10 weeks)
|
Fat mass located in upper extremities (g) measured by dual-energy x-ray absorptiometry
|
Change from pre (baseline) to post test (after 10 weeks)
|
|
Total fat mass change
Time Frame: Change from pre (baseline) to post test (after 10 weeks)
|
Total fat mass (g) measured by dual-energy x-ray absorptiometry
|
Change from pre (baseline) to post test (after 10 weeks)
|
|
Body weight change
Time Frame: Change from pre (baseline) to post test (after 10 weeks)
|
Change from pre (baseline) to post test (after 10 weeks)
|
|
|
Body mass index change
Time Frame: Change from pre (baseline) to post test (after 10 weeks)
|
Change from pre (baseline) to post test (after 10 weeks)
|
|
|
Waist circumference (cm) change
Time Frame: Change from pre (baseline) to post test (after 10 weeks)
|
Change from pre (baseline) to post test (after 10 weeks)
|
|
|
Hip circumference (cm) change
Time Frame: Change from pre (baseline) to post test (after 10 weeks)
|
Change from pre (baseline) to post test (after 10 weeks)
|
Other Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Trunk lean mass change
Time Frame: Change from pre (baseline) to post test (after 10 weeks)
|
Lean mass located in trunk (g) measured by dual-energy x-ray absorptiometry
|
Change from pre (baseline) to post test (after 10 weeks)
|
|
Lower extremity lean mass change
Time Frame: Change from pre (baseline) to post test (after 10 weeks)
|
Lean mass located in lower extremities (g) measured by dual-energy x-ray absorptiometry
|
Change from pre (baseline) to post test (after 10 weeks)
|
|
Upper extremity lean mass change
Time Frame: Change from pre (baseline) to post test (after 10 weeks)
|
Lean mass located in upper extremities (g) measured by dual-energy x-ray absorptiometry
|
Change from pre (baseline) to post test (after 10 weeks)
|
|
Total lean mass change
Time Frame: Change from pre (baseline) to post test (after 10 weeks)
|
Total lean mass (g) measured by dual-energy x-ray absorptiometry
|
Change from pre (baseline) to post test (after 10 weeks)
|
|
Maximal oxygen uptake change
Time Frame: Change from pre (baseline) to post test (after 10 weeks)
|
Maximal oxygen uptake by cardiopulmonary indirect calorimetry
|
Change from pre (baseline) to post test (after 10 weeks)
|
|
Maximal muscle strength change
Time Frame: Change from pre (baseline) to post test (after 10 weeks)
|
One-repetition maximum (kg) in torso rotation and abdominal crunch
|
Change from pre (baseline) to post test (after 10 weeks)
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Collaborators
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
August 1, 2005
Primary Completion (Actual)
May 1, 2006
Study Completion (Actual)
May 1, 2006
Study Registration Dates
First Submitted
March 20, 2023
First Submitted That Met QC Criteria
March 31, 2023
First Posted (Actual)
April 3, 2023
Study Record Updates
Last Update Posted (Actual)
April 3, 2023
Last Update Submitted That Met QC Criteria
March 31, 2023
Last Verified
March 1, 2023
More Information
Terms related to this study
Other Study ID Numbers
- MUCSR12
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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