Validity of Lung Ultrasound in Diagnosis of Acute Respiratory Distress Syndrome

Validity of Lung Ultrasound in Diagnosis of Acute Respiratory Distress Syndrome and Prediction of Successful Weaning From Mechanical Ventilation in Those Patients

To evaluate the validity of lung ultrasound compared to CT chest and chest radiograph for diagnosis of ARDS and prediction of successful weaning from mechanical ventilation in those patients compared to traditional methods.

Study Overview

• Status: Recruiting
• Conditions: of Lung Ultrasound in Diagnosis of Acute Respiratory Distress Syndrome

Detailed Description

57 patients will be diagnosed as ARDS by CT chest and clinical criteria, then will be compared between the findings by lung ultrasound and chest radiograph to detect the sensitivity of both imaging to CT chest as gold standard in diagnosis of ARDS patients

• Study Type: Observational
• Enrollment (Estimated): 57

Contacts and Locations

• Study Contact: Name: Marwa M Medhat, M.D; Phone Number: 0552330832; Email: Medhatmarwa9@gmail.com

Study Locations

• Egypt
  • El Sharkia
    • Zagazig, El Sharkia, Egypt, 44519
      • Recruiting
      • Faculty of Medicine,Zagazig University
      • Contact: marwa m medhat, MD; Phone Number: 01002828937

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Probability Sample

Study Population

patients highly suspected to be ARDS admitted to ICU

Description

Inclusion Criteria:

Patients or legal guardian's consent .All patients with suspicious criteria of acute respiratory distress syndrome .Hemodynamically stable in the absence or minimal of vasopressors.

Exclusion Criteria:

Pregnant women. patients with traumatic lung injury or pneumothorax. surgical dressings over the right lower rib cage which would preclude ultrasound examination. presence of ascites. presence of lung collapse, fibrosis, or pleural effusion.

-presence of any mass or mechanical factor in the chest or the abdomen interfering with the diaphragmatic mobility.

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
diagnostic data checklist	Data of CT chest ,lung ultrasound and chest radiography in diagnosis of ARDS .	immediately after ICU admission

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
success rate	compared the success of both methods in terms of reintubation or not for those patients	within 24 hours after weaning
lung ultrasound as a predictor for weaning	evaluate the scoring of lung aeration	immediately before weaning
diaphragmatic ultrasound as a predictor for weaning	diaphragmatic thickness and excursion	immediately before weaning

Collaborators and Investigators

• Sponsor: Zagazig University
• Investigators: Study Director: mona elharisy, M.D, Zagazig University Faculty of Human Medicine; Principal Investigator: Marwa M Medhat, M.D, Zagazig University Faculty of Human Medicine

Study record dates

Study Major Dates

• Study Start (Actual): June 1, 2022
• Primary Completion (Estimated): September 30, 2023
• Study Completion (Estimated): December 30, 2023

Study Registration Dates

• First Submitted: May 23, 2023
• First Submitted That Met QC Criteria: June 1, 2023
• First Posted (Actual): June 2, 2023

Study Record Updates

• Last Update Posted (Actual): June 26, 2023
• Last Update Submitted That Met QC Criteria: June 22, 2023
• Last Verified: June 1, 2023

More Information

Terms related to this study

• Keywords: lung ultrasound, acute respiratory distress syndrome
• Additional Relevant MeSH Terms: Pathologic Processes; Respiratory Tract Diseases; Respiration Disorders; Lung Diseases; Infant, Newborn, Diseases; Lung Injury; Infant, Premature, Diseases; Syndrome; Disease; Respiratory Distress Syndrome; Respiratory Distress Syndrome, Newborn; Acute Lung Injury
• Other Study ID Numbers: 8053

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No