Exposure to Chemical Substances Within Household Waste Incineration Plants (Chem-Expo)

Evaluation of the Exposure to Chemical Substances of Some of the Employees Working in a Household Waste Incineration Plant

Employees of household waste incineration plants (UIOM) are exposed to multiple chemical substances that can pose a risk to their health.

The studies carried out find increases in certain toxic chemicals (heavy metals, dioxins), in the biological fluids of employees (blood, urine), in particular before the 2000s Another study conducted by Tait finds potential organic alterations.The investigators wish to complete the dissertation work with, in particular, an analysis of the quantitative elements of the exposure assessment (metrologies and biometrologies)

Study Overview

• Status: Recruiting
• Conditions: Exposure to Chemical Pollution, Occupational

Detailed Description

The aim of the study is to evaluate the recorded chemical exposures of certain employees of a household waste incineration plant (UIOM) in order to deduce the risk to their health.

• Study Type: Observational
• Enrollment (Estimated): 50

Contacts and Locations

• Study Contact: Name: Stéphanie KLEINLOGE, MD; Phone Number: 33 3 88 11 64 66; Email: stephanie.kleinlogel@chru-strasbourg.fr

Study Locations

• France
  • Strasbourg, France, 67091
    • Recruiting
    • Service de Pathologie Professionnelle et Médecine du Travail - CHU de Strasbourg - France
    • Contact: Stéphanie KLEINLOGE, MD; Phone Number: 33 3 88 11 64 66; Email: stephanie.kleinlogel@chru-strasbourg.fr
    • Principal Investigator: Stéphanie KLEINLOGE, MD
    • Principal Investigator: Boris DUQUESNEL, MD
    • Sub-Investigator: Azra HAMZIC, MD

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: N/A

• Sampling Method: Non-Probability Sample

Study Population

Adult subject currently working, or having worked in the Strasbourg waste incineration plant between 01/01/2013 and 01/09/2022 within the maintenance or operating team

Description

Inclusion criteria:

• Major subject (≥18 years old)
• Subject currently working, or having worked in the Strasbourg waste incineration plant between 01/01/2013 and 01/09/2022 within the maintenance or operating team
• Subject not objecting, after being informed, to the reuse of their data for the purposes of this research
• Subject in whom one or more biometrologies (blood lead level measurement, urinary cadmium level measurement, urinary 1-hydroxypyrene level measurement) were performed

Exclusion criteria:

-Subject who expressed their opposition to participating in the study

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Retrospective evaluation of the identified chemical exposures of certain employees of a household waste incineration plant (UIOM) in order to deduce the risk to their health.	The study is based on a retrospective analysis of existing data in the files of patients treated by the occupational medicine department	Files analysed retrospectively from 01 January 2013 to 01 September 2022 will be examined

Collaborators and Investigators

• Sponsor: University Hospital, Strasbourg, France

Study record dates

Study Major Dates

• Study Start (Actual): October 10, 2022
• Primary Completion (Estimated): December 1, 2023
• Study Completion (Estimated): December 1, 2023

Study Registration Dates

• First Submitted: December 16, 2022
• First Submitted That Met QC Criteria: December 13, 2023
• First Posted (Actual): December 28, 2023

Study Record Updates

• Last Update Posted (Actual): December 28, 2023
• Last Update Submitted That Met QC Criteria: December 13, 2023
• Last Verified: December 1, 2022

More Information

Terms related to this study

• Keywords: Chemical Pollution
• Other Study ID Numbers: 8721

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No