Syncing Screening and Services for Suicide Prevention Across Health and Jail Systems

Project 1 (Signature): Syncing Screening and Services for Suicide Prevention Across Health and Jail Systems

This study aims to harmonize jail release record data with electronic health record data in order to connect patients to an evidence-based suicide prevention and clinical care pathway upon jail release.

Study Overview

• Status: Recruiting
• Conditions: Suicide Prevention
• Intervention / Treatment: Behavioral: 5S Trial

Detailed Description

This study is designed to test the effectiveness of a care pathway delivered at the time of jail release, to increase behavioral health services engagement and prevent suicide attempt. There are 3 primary aims of this study: (1) Examine the effectiveness of the intervention on suicide attempt outcomes. (2) Evaluate the impact of the intervention on behavioral health utilization mechanisms. (3) Evaluate implementation outcomes and processes to guide future implementation and research, including: cost and cost-effectiveness; scalability; sustainability; feasibility, acceptability, and appropriateness to providers/systems; and implementation strategies.

• Study Type: Interventional
• Enrollment (Estimated): 5250
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Diane Wisnieski, MSW; Phone Number: 313-319-6084; Email: dwisnie2@hfhs.org

Study Locations

• United States
  • Michigan
    • Detroit, Michigan, United States, 48202
      • Recruiting
      • Henry Ford Health
      • Contact: Diane Wisnieski, MSW; Phone Number: 313-319-6084; Email: dwisnie2@hfhs.org
  • Minnesota
    • Bloomington, Minnesota, United States, 55425
      • Recruiting
      • HealthPartners Institute
      • Contact: Caitlin Borgert-Spaniol, MA; Phone Number: 952-883-5421; Email: Caitlin.M.BorgertSpaniol@HealthPartners.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• 18 years of age or older
• Released from jail between February 2021 and July of 2028
• Had a prior primary care visit or behavioral health visit at a participating health system in the past 3 years

Exclusion Criteria:

• Does not currently reside in the same state as the study site (i.e.- Michigan, Minnesota)
• Would require a translator to participate in the research according to EHR data
• Previously requested to be excluded from research

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Health Services Research
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: None (Open Label)

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: 5S Trial; Participants will receive an intervention aimed at suicide prevention in this group.	Behavioral: 5S Trial; Participants will receive caring contacts/recruitment outreach, suicide risk screening, suicide safety planning, and, if indicated, connection to healthcare services, resources and the CLASP virtual outreach intervention.
No Intervention: No-Contact Control Group; Participants will be able to engage with healthcare services as usual and will have no knowledge of their involvement in the study.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Composite measures of suicide attempt and death	Nonfatal medically treated suicide attempts will be identified using diagnosis and encounter codes from all inpatient, outpatient, and emergency department encounters recorded in the EHR (for services delivered by participating systems) or claims (for outside services). All suicide deaths will be identified via linkage to regularly updated state mortality data and the National Death Index (NDI). Suicide deaths will be identified using ICD-10 codes indicating definite or possible self-inflicted injury, or deaths identified as suicides in official state government mortality data (updated monthly in each site).	6-months from jail release date

Collaborators and Investigators

• Sponsor: Henry Ford Health System
• Collaborators: National Institute of Mental Health (NIMH); Brown University; HealthPartners Institute; Michigan State University
• Investigators: Principal Investigator: Lauren Weinstock, PhD, Brown University; Principal Investigator: Brian Ahmedani, PhD, MSW, Henry Ford Health; Principal Investigator: Rebecca Rossom, MD, MS, HealthPartners Institute

Publications and helpful links

General Publications

• Wisnieski DM, Rossom RC, Weinstock LM, Johnson J, Miley K, Gaudiano BA, Benz MB, Borgert-Spaniol C, Graves HR, Norwood R, Kazan R, Starkey C, Kim H, Fletcher L, Kane S, Hu Y, Farrell Z, Strong S, Yeh HH, Miller T, Jones R, Morey K, Ahmedani BK. Study protocol for a type I hybrid effectiveness trial of strategies to prevent suicide attempts among adults recently released from jail. Contemp Clin Trials. 2026 Feb;161:108184. doi: 10.1016/j.cct.2025.108184. Epub 2025 Dec 15.

Study record dates

Study Major Dates

• Study Start (Actual): June 24, 2024
• Primary Completion (Estimated): July 1, 2027
• Study Completion (Estimated): July 1, 2027

Study Registration Dates

• First Submitted: July 11, 2024
• First Submitted That Met QC Criteria: July 11, 2024
• First Posted (Actual): July 17, 2024

Study Record Updates

• Last Update Posted (Actual): June 4, 2026
• Last Update Submitted That Met QC Criteria: June 2, 2026
• Last Verified: June 1, 2026

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Behavioral Symptoms; Self-Injurious Behavior; Suicide; Behavior; Suicide Prevention
• Other Study ID Numbers: 5P50MH127512-02 (U.S. NIH Grant/Contract)

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No