- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT06544824
Accuracy Comparison: Optoelectronic Motion Capture and Markerless System (OPR)
February 25, 2026 updated by: IRCCS Eugenio Medea
Accuracy of Markerless Motion Analysis in Comparison With Optoelectronic Motion Capture System
The purpose of this study was to assess the Openpose reliability to measure kinematics and spatiotemporal gait parameters and to evaluate the minimum technical requirements.
This analysis used video and optoelectronic motion capture simultaneously recorded.
We assessed more of 20 subject with different motor gait impairments
Study Overview
Status
Active, not recruiting
Conditions
Detailed Description
Marker-based Optical motion tracking is the gold standard in gait analysis, but today, markerless solutions are growing rapidly.
Treatment of physical impairments could improve if supported with reliable motion capture.
Moreover, the use of markerless technology offers numerous advantages for working with pediatric populations under various conditions.
In this paper, we assess the Openpose reliability to measure kinematics and spatiotemporal gait parameters and to evaluate the minimum technical requirements., in a population of children with and without gait impairments.
Validating markerless methods can open the way for new motion capture techniques and enhance the accessibility of kinematic measurements and improve the treatment of physical impairments.
Study Type
Observational
Enrollment (Actual)
25
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Italy
-
Bosisio Parini, Italy, Italy, 22037
- IRCCS E. Medea
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
Yes
Sampling Method
Probability Sample
Study Population
This study includes subjects who previously underwent a functional motor assessment using the SMART DX 100 system at the IRCCS Eugenio Medea Institute.
The sample comprises both healthy individuals and those with walking difficulties, all aged over 4 years.
Description
Inclusion Criteria:
- Age over 4 years;
- Ability to walk independently without walking aids and/or orthoses.
Exclusion Criteria:
- Inability to walk independently and safely for short distances without walking aids and/or orthoses.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
|---|---|
|
Healthy subjects
This group includes healthy subjects over 4 years of age; with the ability to walk independently without walking aids and/or orthoses.
|
The two videos were elaborated using OpenPose that returns a set of 25 2D keypoints coordinates for body pose estimation for each video.
Key-points were located in relevant body landmarks and it were used to determine the 2D Cartesian coordinates on the sagittal plane and on the frontal plane.
The data calculated with routines were filtered and interpolated in case of missing data.
With respect to kinematic parameters, the segment and joint angles were measured from the estimated feature points of each joint.
Spatiotemporal gait parameters were calculated using successive heel strike and toe-off events.
The raw data acquired from motion capture system were processed with Smart Analyzer software (BTS Bioengineering, Milano, Italy).
First, the 3D data were filtered and interpolated in case of missing data for short time.
Then spatial-temporal parameters (cycle duration, cadence, gait speed, stance phase, swing phase, double-support phase, stride length and step width) and conventional kinematic parameters of traditional Davis marker-set protocols were computed.
|
|
Subjects with a diagnosis of cerebral palsy and right hemiplegia
This group includes subjects with a diagnosis of cerebral palsy and right hemiplegia over 4 years of age; with the ability to walk independently without walking aids and/or orthoses.
|
The two videos were elaborated using OpenPose that returns a set of 25 2D keypoints coordinates for body pose estimation for each video.
Key-points were located in relevant body landmarks and it were used to determine the 2D Cartesian coordinates on the sagittal plane and on the frontal plane.
The data calculated with routines were filtered and interpolated in case of missing data.
With respect to kinematic parameters, the segment and joint angles were measured from the estimated feature points of each joint.
Spatiotemporal gait parameters were calculated using successive heel strike and toe-off events.
The raw data acquired from motion capture system were processed with Smart Analyzer software (BTS Bioengineering, Milano, Italy).
First, the 3D data were filtered and interpolated in case of missing data for short time.
Then spatial-temporal parameters (cycle duration, cadence, gait speed, stance phase, swing phase, double-support phase, stride length and step width) and conventional kinematic parameters of traditional Davis marker-set protocols were computed.
|
|
Subjects with a diagnosis of cerebral palsy and left hemiplegia
This group includes subjects with a diagnosis of cerebral palsy and left hemiplegia over 4 years of age; with the ability to walk independently without walking aids and/or orthoses.
|
The two videos were elaborated using OpenPose that returns a set of 25 2D keypoints coordinates for body pose estimation for each video.
Key-points were located in relevant body landmarks and it were used to determine the 2D Cartesian coordinates on the sagittal plane and on the frontal plane.
The data calculated with routines were filtered and interpolated in case of missing data.
With respect to kinematic parameters, the segment and joint angles were measured from the estimated feature points of each joint.
Spatiotemporal gait parameters were calculated using successive heel strike and toe-off events.
The raw data acquired from motion capture system were processed with Smart Analyzer software (BTS Bioengineering, Milano, Italy).
First, the 3D data were filtered and interpolated in case of missing data for short time.
Then spatial-temporal parameters (cycle duration, cadence, gait speed, stance phase, swing phase, double-support phase, stride length and step width) and conventional kinematic parameters of traditional Davis marker-set protocols were computed.
|
|
Subjects with a diagnosis of spastic paraparesis
TThis group includes subjects with a diagnosis of spastic paraparesis over 4 years of age; with the ability to walk independently without walking aids and/or orthoses.
|
The two videos were elaborated using OpenPose that returns a set of 25 2D keypoints coordinates for body pose estimation for each video.
Key-points were located in relevant body landmarks and it were used to determine the 2D Cartesian coordinates on the sagittal plane and on the frontal plane.
The data calculated with routines were filtered and interpolated in case of missing data.
With respect to kinematic parameters, the segment and joint angles were measured from the estimated feature points of each joint.
Spatiotemporal gait parameters were calculated using successive heel strike and toe-off events.
The raw data acquired from motion capture system were processed with Smart Analyzer software (BTS Bioengineering, Milano, Italy).
First, the 3D data were filtered and interpolated in case of missing data for short time.
Then spatial-temporal parameters (cycle duration, cadence, gait speed, stance phase, swing phase, double-support phase, stride length and step width) and conventional kinematic parameters of traditional Davis marker-set protocols were computed.
|
|
healthy children mimic gesture
This group includes a sample of healthy subjects who mimic the chimney tip typical of some diseases such as cerebral palsy and autism.
|
The two videos were elaborated using OpenPose that returns a set of 25 2D keypoints coordinates for body pose estimation for each video.
Key-points were located in relevant body landmarks and it were used to determine the 2D Cartesian coordinates on the sagittal plane and on the frontal plane.
The data calculated with routines were filtered and interpolated in case of missing data.
With respect to kinematic parameters, the segment and joint angles were measured from the estimated feature points of each joint.
Spatiotemporal gait parameters were calculated using successive heel strike and toe-off events.
The kinematic features calculated are used to identify and count the number of tip toe steps during gait or standing
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Absolute Error
Time Frame: Through study completion, an average of 1 year
|
Absolute errors were calculated for the kinematics parameters and for each spatiotemporal variable by taking the absolute value after subtracting the values obtained using pose estimation methods from the value measured using markerbased motion capture
|
Through study completion, an average of 1 year
|
|
intraclass correlation coefficients
Time Frame: Through study completion, an average of 1 year
|
To confirm whether the data obtained by OpenPose agreed with the data from the optoelectronic system, investigators calculated the ICCs (two-way mixed effects model, absolute agreement, average measurements) between the spatiotemporal and kinematic data from both systems.
The ICC values were interpreted as follows: poor agreement for ICC < 0.5, moderate agreement for values between 0.5 and 0.75, good agreement for values between 0.75 and 0.9, and excellent agreement for values greater than 0.90.
|
Through study completion, an average of 1 year
|
|
cross-correlation coefficients
Time Frame: Through study completion, an average of 1 year
|
The cross-correlation coefficients (CCC) between both systems were used to evaluate the similarity of angles during the gait cycle.
The CCC values were interpreted as follows: weak or no coupling for values between -0.3 and 0.3, moderate coupling for values between 0.3 and 0.7 or -0.7 and -0.3, and strong coupling for values greater than 0.7 or less than -0.7.
|
Through study completion, an average of 1 year
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Giuseppe Andreoni, IRCCS E.Medea
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
May 15, 2024
Primary Completion (Estimated)
September 24, 2026
Study Completion (Estimated)
September 24, 2026
Study Registration Dates
First Submitted
August 5, 2024
First Submitted That Met QC Criteria
August 5, 2024
First Posted (Actual)
August 9, 2024
Study Record Updates
Last Update Posted (Actual)
February 27, 2026
Last Update Submitted That Met QC Criteria
February 25, 2026
Last Verified
February 1, 2026
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- GIP1121
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
product manufactured in and exported from the U.S.
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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