The Effects of Dual Task Training With Different Task Priorities on Physical Performance and Cognitive Status in Patients With Parkinson's Disease

Investigation of the Effects of Dual Task Training With Different Task Priorities on Physical Performance and Cognitive Status in Patients With Parkinson's Disease

This study was planned to investigate and compare the effects of variable and fixed priority dual task training on balance, walking skills, mobility and cognition in patients with Parkinson's disease.

Study Overview

• Status: Completed
• Conditions: Walking; Cognition; Parkinson's Disease (PD); Mobility; Balance; Dual-task
• Intervention / Treatment: Other: Single task training; Other: Variable priority dual task training; Other: Fixed priority dual task training

• Study Type: Interventional
• Enrollment (Actual): 30
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Turkey (Türkiye)
  • Ankara, Turkey (Türkiye), 06018
    • Sağlık Bilimleri Üniversitesi, Gülhane Fizyoterapi ve Rehabilitasyon Fakültesi
  • Ankara, Turkey (Türkiye), 06560
    • Gazi Üniversitesi Tıp Fakültesi Nöroloji Anabilim Dalı

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

Description

Inclusion Criteria:

• Having agreed to participate in the research after being given detailed information about the research.
• Having been diagnosed with Parkinson's disease by a specialist neurologist according to the UK Brain Bank criteria
• Being in stage 1-3 according to Hoehn & Yahr
• Being 40 years of age or older

Exclusion Criteria:

• Having a neurological condition other than Parkinson's disease
• Cognitive impairment
• Have undergone deep brain stimulation surgery
• Having a visual, auditory or perceptual problem
• Having any orthopedic, rheumatological or other disease that may affect walking and balance.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

3

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Contol Group; Single task training	Other: Single task training; Single task training with balance and walking exercises, twice a week for six weeks
Experimental: Variable priority dual task training group; Variable priority dual task training	Other: Variable priority dual task training; Variable priority dual task training with balance and walking exercises performed simultaneously with cognitive tasks, twice a week for six weeks
Experimental: Fixed priority dual task training group; Fixed priority dual task training	Other: Fixed priority dual task training; Fixed priority dual task training with balance and walking exercises performed simultaneously with cognitive tasks, twice a week for six weeks

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Hoehn and Yahr Scale	A staging system that quickly provides information in determining the degree and symptom severity of the disease	Baseline, 6 weeks
Unified Parkinson's Disease Rating Scale	Evaluates cognitive skills, mood, activities of daily living, motor skills, motor fluctuations, dyskinesias, and autonomic dysfunction in four parts	Baseline, 6 weeks
Berg Balance Scale	It includes 14 functional activities to assess static and proactive balance. The total score ranges from 0 to 56, with higher scores indicating better balance.	Baseline, 6 weeks
Functional Reach Test	The test is designed to assess dynamic balance by measuring the maximum distance that a person can reach forward beyond arm's length without taking a step.	Baseline, 6 weeks
Single Leg Stance Test	It is a test method used to evaluate static balance. One foot is lifted without touching the supporting leg and the person is expected to maintain their balance for 30 seconds.	Baseline, 6 weeks
Four Square Step Test	It is a test method used to evaluate dynamic balance. Two canes are placed on a flat surface to create 4 squares. All squares are numbered. The subject starts in one square and steps in one direction into each of the four squares and then reverses direction back to the start. The time (in seconds) taken to complete the sequence is measured.	Baseline, 6 weeks
10 Meter Walk Test	Used to assess walking speed. Participants are asked to walk a distance of 10 meters and the time taken is recorded.	Baseline, 6 weeks
Figure-of-Eight Walk Test	The participant stands still at the midpoint of two cones placed 1.52 m apart and begins walking around the cones in a figure eight at his/her usual pace. The total time and number of steps taken to complete the test are recorded.	Baseline, 6 weeks
3-Meter Backward Walk Test	The 3-meter distance is measured and marked. Participants are asked to walk backwards as quickly as possible with the "walk" command and to stop when they reach 3 meters. The elapsed time is recorded in seconds.	Baseline, 6 weeks
Timed Up and Go Test	It is used to assess functional mobility level. The participant is asked to stand up from the chair, walk 3 m, turn around, walk back to the chair and sit down. The test starts with the "walk" command and the completion time is recorded in seconds.	Baseline, 6 weeks
Unified Parkinson's Disease Rating Scale, Part 2	UPDRS Part 2 generally is considered a psychometrically reliable tool for measuring activities of daily living outcomes in people with Parkinson's disease.	Baseline, 6 weeks
Dual Task Questionnaire	It is used to obtain information about the difficulties experienced in daily tasks related to dual task. It consists of 10 questions, each question is scored between 0 and 4.	Baseline, 6 weeks
Trail Making Test	It is used to evaluate individuals' visual scanning speed, executive functions, visual-motor perception, motor function, planning, organization, abstract thinking and response limitation. The test consists of 2 parts: A and B. In part A, the individual is asked to combine numbers from 1 to 25 and the completion time is recorded. In part B, the individual completes the sequence by corresponding to a number and a letter, and the completion time is recorded.	Baseline, 6 weeks
Stroop Test	It is a test that evaluates executive functions and the suppression of inappropriate automatic responses and provides information about frontal functions.	Baseline, 6 weeks
Symbol Digit Modalities Test	It is a test that measures working memory and information processing speed. In the upper right corner of the A4 paper used in the test, there is a grid of shapes, each representing a number. In the other parts of the paper, there are randomly arranged shapes in blocks. During the test, patients are asked to match these shapes with the numbers in the grid.	Baseline, 6 weeks
Word List Generation	It is a test used to evaluate complex attention functions and vocabulary. It consists of animal and KAS sections. First, the patient is asked to name every animal that comes to mind in one minute, as quickly as possible. In the KAS section, the patient is asked to name every word that comes to mind, except for proper nouns and city names, with the letters K-A-S in order. The time for each letter is again one minute.	Baseline, 6 weeks
Tampa Scale for Kinesiophobia	It is a 17-question scale developed to measure fear of movement/re-injury. The scale includes parameters of injury/re-injury and fear-avoidance in work-related activities. Each item is scored between 1-4.	Baseline, 6 weeks

Collaborators and Investigators

• Sponsor: Hacettepe University
• Collaborators: Gazi University; Saglik Bilimleri Universitesi

Study record dates

Study Major Dates

• Study Start (Actual): February 1, 2024
• Primary Completion (Actual): September 30, 2025
• Study Completion (Actual): September 30, 2025

Study Registration Dates

• First Submitted: January 21, 2025
• First Submitted That Met QC Criteria: January 21, 2025
• First Posted (Actual): January 27, 2025

Study Record Updates

• Last Update Posted (Estimated): October 6, 2025
• Last Update Submitted That Met QC Criteria: October 2, 2025
• Last Verified: October 1, 2025

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Synucleinopathies; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Neurodegenerative Diseases; Movement Disorders; Parkinsonian Disorders; Basal Ganglia Diseases; Parkinson Disease
• Other Study ID Numbers: 285 (National Heart, Lung, and Blood Institute)

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No