Modified Nuclear Phacoemulsification in Brown Cataract

November 19, 2025 updated by: Hassan Lotfy Fahmy, Assiut University

Modified Technique for Nuclear Phacoemulsification in Brown Cataractous Nucleus

Irrigation of the nucleus with saline for 30 seconds after creating the central groove.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

The hard nucleus is physiologically immune against water flow from out to inside the nucleus but we discovered that it is not immune against the flow of water from inside the nucleus to outside. So, we are doing phacoemulsification as usual, but we stop when the gutter becomes half the thickness of the nucleus, then we use the tip of the phaco as irrigation for 30 seconds. the nucleus will become softer.

. As we know, the nucleus of the lens has the highest concentration of crystalline (high osmotic pressure), so the water will flow from the center of the nucleus to the outer surface without any resistance, and all adhesions and bonds between lens fibers will be broken at once, and the nucleus becomes softer.

Study Type

Interventional

Enrollment (Actual)

20

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Asyut, Egypt, 71111
        • Assiut univercity

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Brown cataract

Exclusion Criteria:

  • white cataract
  • soft cataract

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Brown cataract
doing phacoemulsification as usual, but we stop when the gutter becomes half the thickness of the nucleus, then we use the tip of the phaco as irrigation for 30 seconds. the nucleus will become softer
Procedure: phacoemulsification
doing phacoemulsification as usual but we stop when the gutter becomes half the thickness of the nucleus then we use tip of the phaco as irrigation for 30 seconds. the nucleus will become more softer

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
phaco time
Time Frame: 60 seconds
time of ultrasound power
60 seconds

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Assiut University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

March 1, 2025

Primary Completion (Actual)

November 1, 2025

Study Completion (Actual)

November 1, 2025

Study Registration Dates

First Submitted

November 19, 2025

First Submitted That Met QC Criteria

November 19, 2025

First Posted (Actual)

November 26, 2025

Study Record Updates

Last Update Posted (Actual)

November 26, 2025

Last Update Submitted That Met QC Criteria

November 19, 2025

Last Verified

November 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 17209067

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

Yes

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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