Effect Of Sensory Motor Training Versus Resistance Training Among Individuals With Knee Osteoarthritis.

November 28, 2025 updated by: Lahore University of Biological and Applied Sciences

Effect Of Sensory Motor Training Versus Resistance Training On Improving Pain, Balance And Functional Activities Among Individuals With Knee Osteoarthritis

This study aims to address this gap by comparing the effects of sensory-motor training versus resistance training on pain, balance and functional activities, specifically in patients with early-stage knee osteoarthritis. In Pakistan, Knee Osteoarthritis is a common condition that significantly impacts many individuals' quality of life. While research exists on various exercise interventions for knee osteoarthritis, there is limited focus on patients with Grade 1 and 2 osteoarthritis. Understanding the most effective training method for this group will provide valuable insights for developing targeted rehabilitation programs, ultimately improving patient outcomes and quality of life.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Detailed Description

Osteoarthritis of the knee is a degenerative condition that gradually affects the synovial joints. Following the stress, joint become damaged and unable to repair and is triggered by asymmetry in synovial tissues of joint such as articular cartilage, ligaments, subchondral bone, periarticular musculature, menisci, synovia or peripheral nerves. This structural harm leads to the breakdown of subchondral bone and cartilage, resulting in symptoms like stiffness, pain, and limited range of motion. It is just like a plane surface of road becoming uneven and pitted. Osteoarthritis of knee joint debilitates the individuals and they totally rely on others.

Interventions for treating knee osteoarthritis include pharmacological and therapeutic technique. Present clinical recommendations in grade 1 and 2 favor conservative management, like physical therapy, use of assistive devices and weight management due to their simplicity, minimal side effects, and more economical. Due to extensive evidence showing the positive impact of physical activity on individuals with osteoarthritis, exercise is frequently recommended as a key element in the rehabilitation journey.

In various physical workout plans, muscle strengthening holds significance due to the connection between pain, muscle weakness, and limited function. Yet, standard strengthening routines might not suffice for individuals having functional joint instability. A research study on this specific group of patients explored treatments targeting symptoms directly, aiming to enhance the efficiency of the rehabilitation regimen. Recently awareness has been given by focusing on sensory inputs such as balance and proprioception exercises. It may allow individual to adapt motor skills for dealing with disability on knee. Sensorimotor training is an effective treatment to restore motor programs in patients among different musculoskeletal disorders and chronic musculoskeletal pain. It adopts a phase-oriented treatment approach and consists of regulation of arousal, emotion and behavior.

The goal of sensorimotor therapy training in knee osteoarthritis is to gain functional activities, relieve pain. As osteoarthritis advances, sensory-motor abilities like neuromuscular control, static and dynamic balance, and proprioception decrease due to reduced daily physical activities and heightened pain perception. Therefore, incorporating agility, coordination, and balance exercises such as cross steps while walking backward, walking on unsymmetrical surfaces and verbal commands by therapist can be beneficial by challenging individuals with disruptive loads. This exposure helps the neuromuscular system adapt to situations that may trigger knee instability during daily activities. Resistance training refers to a workout method where muscles are engaged against a resistance or weight. This training approach aids in strength enhancement, muscle building, and endurance improvement. It encompasses utilizing weights, resistance bands, or engaging in bodyweight exercises. The benefits of resistance training include overall fitness enhancement, bone density improvement, metabolism boost, and better physical performance. Proper execution of resistance training is crucial to prevent injuries and optimize workout effectiveness

Study Type

Interventional

Enrollment (Estimated)

52

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Pakistan
    • Punjab Province
      • Lahore, Punjab Province, Pakistan, 54000
        • Lahore UBAS

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Both males and females are included.
  • Age group include 40-60 years.
  • Not done any exercise for at least 3 months
  • Tibiofemoral osteoarthritis
  • Grade I and II osteoarthritis

Exclusion Criteria:

  • • Cardiorespiratory diseases.

    • Uncontrolled diabetes and Hypertension.
    • Using ambulatory devices.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Sensory Motor Group
Participants in the sensory-motor training group received 8-week program of exercise 2 times a week. It starts with a warm-up on stationary bicycle for 10 minutes, stretching exercises.
Other: Sensory motor training

7.8. Interventions i FITT Principle: F: 2 times a week I: maximum to minimum T: Group 1 SMT, Group 2 RT T: 40-50 min Individuals were assigned 1:1 to either sensory motor training or resistance training.

ii Groups with sufficient details

1 Experimental: Group1: Participants in the sensory-motor training group received 8-week program of exercise 2 times a week. It starts with a warm-up on stationary bicycle for 10 minutes, stretching exercises. In this group the main focus was on agility exercises that includes a balance board, walking on different directions, crossing steps while walking backward and forward and walking on different surfaces. The duration for these exercises was 40-50 minutes per session.
Active Comparator: Resistance training group
The individuals allocated to the resistance training received a same 8-weeks exercise program twice a week. Exercise began with the same warm-up on stationary bicycle for 10 minutes then traction was applied, Isometric hip flexion and leg extension, stretching exercises for lower limb, Quadriceps and hamstring strengthening using ankle weights were used with frequency twice a week. 3 sets of 10 repetitions at 30 to 40% of 1RM and low to moderate intensity loads were applied for 15 minutes bilaterally.
Other: Resistance Training
The individuals allocated to the resistance training received a same 8-weeks exercise program twice a week. Exercise began with the same warm-up on stationary bicycle for 10 minutes then traction was applied, Isometric hip flexion and leg extension, stretching exercises for lower limb, Quadriceps and hamstring strengthening using ankle weights were used with frequency twice a week. 3 sets of 10 repetitions at 30 to 40% of 1RM and low to moderate intensity loads were applied for 15 minutes bilaterally.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Visual Analogue Scale (VAS - Pain Outcome)
Time Frame: 8 weeks

The Visual Analogue Scale is a simple, reliable tool used to quantify pain intensity on a 10 cm line ranging from "no pain" to "worst possible pain." Participants marked their pain level experienced in both knees over the past 24 hours.

It allows sensitive detection of even small changes in perceived pain.
8 weeks
WOMAC Scale (Functional Activities Outcome)
Time Frame: 8 weeks

The WOMAC Index is a validated questionnaire designed to evaluate pain, stiffness, and physical function specifically in individuals with knee or hip osteoarthritis.

It assesses daily functional limitations such as walking, stair climbing, and standing.

Higher scores indicate greater impairment, making it useful for monitoring treatment-related improvements.
8 weeks

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Timed Up and Go (TUG) Test - Balance Outcome
Time Frame: 8 Weeks

The Timed Up and Go test measures functional mobility, dynamic balance, and fall risk by timing how long a person takes to stand up from a chair, walk 3 meters, turn, return, and sit down.

It is quick, practical, and widely used in clinical settings. Longer completion times indicate poorer balance and mobility.
8 Weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Lahore University of Biological and Applied Sciences

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

December 1, 2025

Primary Completion (Estimated)

June 1, 2026

Study Completion (Estimated)

June 1, 2026

Study Registration Dates

First Submitted

November 19, 2025

First Submitted That Met QC Criteria

November 28, 2025

First Posted (Estimated)

December 4, 2025

Study Record Updates

Last Update Posted (Estimated)

December 4, 2025

Last Update Submitted That Met QC Criteria

November 28, 2025

Last Verified

November 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 21657

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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