Comparison Of Analgesic Methods İn Video-Assisted Thoracoscopic Surgery

August 10, 2026 updated by: Renim Yüksel, Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Comparıson Of The Postoperatıve Analgesıc Effıcacy Of Serratus Anterıor Plane Block And Serratus Posterıor Superıor Intercostal Plane Block Performed Under Ultrasonography Guıdance In Vıdeo-Assısted Thoracoscopıc Surgery

Comparison of the Analgesic Efficacy of Serratus Anterior Plane Block and Serratus Posterior Superior Intercostal Plane Block in Patients Undergoing Video-Assisted Thoracoscopic Surgery Introduction and Objective: The aim of this study is to compare the postoperative analgesic efficacy of the serratus anterior plane block and serratus posterior superior intercostal plane block performed under ultrasonography guidance in patients undergoing video-assisted thoracoscopic surgery.

Patients with ASA grades I-III, aged 18-65, will be included in the study. Standard general anesthesia will be administered to the patients. Postoperative analgesia evaluation will be conducted using VAS and NRS scores at specific time points after surgery Additional analgesic requirements and patient satisfaction will be recorded.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

60

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Turkey (Türkiye)
    • Kayapınar
      • Diyarbakır, Kayapınar, Turkey (Türkiye), 21100
        • University of Health Siences Gazi Yasargil Training and Research Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Patient aged between 18 and 65 years ASA physical status I-III Scheduled for elective video-assisted thoracoscopic surgery (VATS) Provided written information consent

Exclusion Criteria:

  • History of allergy or toxicity to local anesthetic agents
  • Known or suspected coagulopathy
  • Infection at the site of block injection
  • Advanced organ failure
  • Diagnosed mental retardation
  • Pregnancy
  • Pediatric patients
  • History of thoracotomy
  • Requirement for postoperative intubation
  • Emergency surgery
  • Refusal to participate in the study

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Triple

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: SERRATUS ANTERİOR PLANE BLOCK
Participants received an ultrasound-guieded serratus anterior plane block (SAPB)
Procedure: Ultrasound guided serratus anterior plane block
Ultrasound-guided serratus anterior plane block was performed at the 4th intercostal level in the mid-axillary line using an in plane technique. A total of 30 ml of %0.25 bupivacaine was injected into the fascial plane between the latissumus dorsi and serratus anterior muscles (unilateral)
Other Names:
  • serratus anterior plane block
Experimental: SERRATUS POSTERİOR SUPERİOR İNTERCOSTAL PLANE BLOCK
Participants received an ultrasound-guided serratus posterior superior intercostal plane block (SPSIPB)
Procedure: Ultrasound guided serratus posterior superior intercostal plane block
Ultrasound-guided serratus posterior superior intercostal plane block was performed using an in plane technique. A total of 30 ml of %0.25 bupivacaine was injected into the fascial plane between the serratus posterior superior and intercostal muscles at the 3rd rib level via a posterior approach (unilateral)
Other Names:
  • Serratus posterior superior intercostal plane block

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Postoperative pain intensity
Time Frame: At postoperative 30 minute and 1, 4, 8, 12, 24 hours
Postoperative pain intensity was assessed using the Visual Analog Scale (VAS) where 0 indicates no pain and 10 indicates the worst imaginable pain
At postoperative 30 minute and 1, 4, 8, 12, 24 hours

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Postoperative pain intensity assessed by Numeric Rating Scale (NRS)
Time Frame: 30 minutes, 1, 4, 8, 12, 24 hours after surgery
Postoperative pain intensity will be assessed using the Numeric Rating Scale (NRS), ranging from 0 (no pain) to 10 (worst pain imaginable)
30 minutes, 1, 4, 8, 12, 24 hours after surgery
Total 24-hour tramadol consumption
Time Frame: 24 hours after surgery
Total amount of rescue tramadol administered within the first 24 postoperative hours, recorded in milligrams
24 hours after surgery
Rescue analgesia requirement
Time Frame: At postoperative 30 minute and 1, 4, 8, 12, 24 hours
Proportion of patients requiring rescue analgesia (intravenous tramadol) at each postoperative assessment time point
At postoperative 30 minute and 1, 4, 8, 12, 24 hours
Adverse events
Time Frame: Within 24 hours after surgery
Incidence of local anesthetic systemic toxicity, pneumothorax, hypotension, nausea/vomiting, and block-related complications
Within 24 hours after surgery
Dynamic (movement-associated) postoperative pain intensity
Time Frame: At postoperative 30 minute and 1, 4, 8, 12, 24 hours
Postoperative pain intensity during movement/coughing was assessed using the Visual Analog Scale (VAS), distinct from the primary outcome which assessed pain at rest (static VAS)
At postoperative 30 minute and 1, 4, 8, 12, 24 hours

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 13, 2025

Primary Completion (Actual)

July 11, 2025

Study Completion (Actual)

October 13, 2025

Study Registration Dates

First Submitted

January 24, 2026

First Submitted That Met QC Criteria

February 1, 2026

First Posted (Actual)

February 9, 2026

Study Record Updates

Last Update Posted (Actual)

August 12, 2026

Last Update Submitted That Met QC Criteria

August 10, 2026

Last Verified

January 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 225

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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