- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07679048
Measuring How Quickly the Eye Focuses After Sustained Viewing of Close-up Images and Videos
June 25, 2026 updated by: Benjamin Chin, Rochester Institute of Technology
A Randomized, Repeated-measures Study to Measure the Temporal Frequency Response of Ocular Accommodation After Sustained Near Viewing.
In this experiment, subjects will view a cross pattern on the screen and be asked to focus their eyes on it.
The cross pattern will look like it is moving towards and away from the eye in a back-and-forth motion.
As the subjects focus their eyes on the shapes, we will measure the focus of their eyes using a device called a wavefront sensor.
This device uses infrared light to measure the optical properties of the eye in real time.
Our goal is to find out how well the eye focuses before and after viewing images on a screen up close (25cm).
Since many people spend a lot of time looking at a computer screen while at work or at school, it is important to understand how this affects the eye's ability to focus.
Study Overview
Status
Recruiting
Conditions
Intervention / Treatment
Detailed Description
In this experiment, subjects will view a Maltese cross pattern on a display through a Badal relay.
Subjects will be instructed to accommodate to the pattern while a focus-adjustable lens optically moves the display closer and farther in depth as a sinusoidal function of time.
As they do so, we will measure the wavefronts of their eyes using a Shack-Hartmann wavefront sensor.
We will measure the gain and phase of the accommodative response of the subjects' eyes.
Measurements will be made before and after sustained viewing of images on a computer screen 25cm away.
Study Type
Interventional
Enrollment (Estimated)
20
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Benjamin M Chin, Doctorate
- Phone Number: 8454534320
- Email: bmccis@rit.edu
Study Locations
-
-
New York
-
Rochester, New York, United States, 14623
- Recruiting
- Chester F. Carlson Center for Imaging Science
-
Contact:
- Benjamin M Chin, Doctorate
- Phone Number: 8454534320
- Email: bmccis@rit.edu
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
Accepts Healthy Volunteers
Yes
Description
Inclusion Criteria:
- We will recruit participants for inclusion who are adults in the age range of 18-35 years, because these are the ages at which people's eyes are able to focus at near distances.
Exclusion Criteria:
- Participants will be screened for having normal or corrected-to-normal (glasses/contacts) vision. Participants with vision worse than 20/20 will be excluded. People with fragile or loose teeth will be excluded because participants need to bite a piece of dental clay to stabilize their heads so that measurements can be taken from their eyes (too much head and eye movement disrupts the measurement). People who are pregnant, with heart disease, or personal/familial history of epilepsy will be excluded because some studies recommend against them viewing computer displays while sitting down for an extended period of time.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Basic Science
- Allocation: Randomized
- Interventional Model: Crossover Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Experimental: Near viewing first first
In a given session of the experiment (1.5 hours), participants do 2 sets of accommodation tasks.
One task happens after viewing a screen for 20 minutes at 25cm, and the other task happens after looking at a distant object (10m) for 20 minutes.
There are two types of sessions: one in which the screen is viewed first ('near viewing first'), and the other in which the distant object is viewed first ('distant viewing first').
All participants do both sessions.
However, in one arm, participants do the 'near viewing first' session first.
|
In a given session of the experiment (1.5 hours), participants do 2 sets of accommodation tasks.
One task happens after viewing a screen for 20 minutes at 25cm, and the other task happens after looking at a distant object (10m) for 20 minutes.
In one intervention, the session is structured such that the screen is viewed first ('near viewing first').
In a given session of the experiment (1.5 hours), participants do 2 sets of accommodation tasks.
One task happens after viewing a screen for 20 minutes at 25cm, and the other task happens after looking at a distant object (10m) for 20 minutes.
In one intervention, the session is structured such that the distant object is viewed first ('distant viewing first').
|
|
Experimental: 'Distant viewing first' first
In a given session of the experiment (1.5 hours), participants do 2 sets of accommodation tasks.
One task happens after viewing a screen for 20 minutes at 25cm, and the other task happens after looking at a distant object (10m) for 20 minutes.
There are two types of sessions: one in which the screen is viewed first ('near viewing first'), and the other in which the distant object is viewed first ('distant viewing first').
All participants do both sessions.
However, in one arm, participants do the 'distant viewing first' session first.
|
In a given session of the experiment (1.5 hours), participants do 2 sets of accommodation tasks.
One task happens after viewing a screen for 20 minutes at 25cm, and the other task happens after looking at a distant object (10m) for 20 minutes.
In one intervention, the session is structured such that the screen is viewed first ('near viewing first').
In a given session of the experiment (1.5 hours), participants do 2 sets of accommodation tasks.
One task happens after viewing a screen for 20 minutes at 25cm, and the other task happens after looking at a distant object (10m) for 20 minutes.
In one intervention, the session is structured such that the distant object is viewed first ('distant viewing first').
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Gain and phase of ocular accommodation
Time Frame: Each measurement takes 10 seconds. In the experiment, we will take measurements over the course of approximately 1 hour.
|
Ocular accommodation is the focusing response of the lens in the eye.
When the stimulus viewed by the participant changes in distance, the eye automatically refocuses.
We measure this refocusing using a device called a wavefront sensor.
We are particularly interested in the gain of accommodation, which is the ratio of the amplitude of accommodation to the amplitude of sinusoidal changes in stimulus distance.
We are also interested in the phase of the accommodative response, which is related to the lag of the accommodative response.
|
Each measurement takes 10 seconds. In the experiment, we will take measurements over the course of approximately 1 hour.
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Collaborators
Investigators
- Principal Investigator: Benjamin M Chin, Doctorate, Rochester Institute of Technology
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Estimated)
June 25, 2026
Primary Completion (Estimated)
December 15, 2026
Study Completion (Estimated)
December 15, 2026
Study Registration Dates
First Submitted
June 25, 2026
First Submitted That Met QC Criteria
June 25, 2026
First Posted (Actual)
July 1, 2026
Study Record Updates
Last Update Posted (Actual)
July 1, 2026
Last Update Submitted That Met QC Criteria
June 25, 2026
Last Verified
June 1, 2026
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- IRB0000131-Exp2
- 4R00EY036497-03 (U.S. NIH Grant/Contract)
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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