Clinical Trials on Airway Clearance Impairment in South Africa

Total 89 results

University of Cape Town
Red Cross War Memorial Children's Hospital

Unknown

Endotracheal Dilator to Improve Oxygenation (EDITION2)

Pediatric Respiratory Diseases | Tracheal Stenosis | Airway Disease

South Africa
Novartis Pharmaceuticals

Completed

A Phase l Study to Evaluate the Pharmacokinetics and Safety Pasireotide in Subjects With Varying Degrees of Renal Impairment Compared to Healthy Volunteers

Renal Impairment

Germany, South Africa
Brno University Hospital
Masaryk University

Recruiting

Head Position for Laryngeal Mask Air Leak and Performance in Paediatric Patients (Neutral, Sniffing and Beyond Sniffing Position) (SNIFFLMA)

Airway Management

Czechia
Prisma Health-Upstate
Vanderbilt University

Enrolling by invitation

Airway Management Skills Amongst Anesthesia Providers

Airway Management

United States
Novartis Pharmaceuticals

Terminated

Effect of AQW051 in Patients With Memory Impairment

Amnestic Mild Cognitive Impairment | Mild Alzheimer's Disease

Canada, United Kingdom, South Africa
Novartis Pharmaceuticals

Completed

Single-dose Iloperidone Pharmacokinetics in Patients With Mild or Moderate Liver Disease, Compared to Healthy Volunteers

Hepatic Impairment

United States
Cochlear
Avania

Completed

CP1150 Sound Processor Speech Perception Compared With the Next Generation of Signal Processing Technology

Hearing Impairment, Sensorineural

Australia
VA Office of Research and Development

Completed

rTMS for Emotional Difficulties in Verterans (rTMS)

Depression | PTSD | Anxiety | Mental Health | Psychosocial Impairment | rTMS

United States
Ono Pharma USA Inc
Ono Pharmaceutical Co. Ltd

Completed

An Open-label, Single-dose, Intravenous Administration Study of ONO-2745/CNS 7056 in Subjects With Chronic Hepatic Impairment

Healthy | Hepatic Impairment

United States
The George Institute
Chinese University of Hong Kong; Monash University; The Alfred; University of Sydney and other collaborators

Recruiting

Statin TReatment for COVID-19 to Optimise NeuroloGical recovERy (STRONGER)

Neurocognitive Impairment, Mild

Australia
Medical University of South Carolina
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes...

Recruiting

rTMS in Older Adults With MCI and AUD

Transcranial Magnetic Stimulation | Mild Cognitive Impairment | Alcohol Use Disorder

United States
Medical University of South Carolina
National Center of Neuromodulation for Rehabilitation

Completed

Plasticity Using Stimulation and Habit: A Pilot Open-label rTMS Study for MCI (PUSH-Pilot)

Mild Cognitive Impairment

United States
The University of New South Wales

Completed

Transcranial Direct Current Stimulation to Enhance Cognition in Mild Cognitive Impairment

Mild Cognitive Impairment

Australia
Medical University of South Carolina
National Institute on Aging (NIA)

Recruiting

Transcranial Magnetic Stimulation for MCI (PUSH2)

Depression | Mild Cognitive Impairment

United States
Nutricia Research

Unknown

Neocate In Infants and Children With Complex Conditions (NICC)

Complex Conditions, Including Impairment of the GI Tract

United Kingdom, United States, Germany
Medical University of South Carolina
National Institutes of Health (NIH)

Recruiting

Learning in Stroke

Stroke | Sensorimotor Impairment

United States
University of Western Sydney

Completed

Memory Encoding Strategies for People With Mild Cognitive Impairments

Mild Cognitive Impairment | Mild Dementia

Hong Kong, Australia
Westat
United States Social Security Administration

Completed

Supported Employment Demonstration (SED)

Mental Impairment

United States
Eisai Inc.
Eisai Limited

Completed

Efficacy and Safety of Donepezil Hydrochloride in Preadolescent and Adolescent Children With Attention Impairment Following Cancer Treatment

Attention Impairment

United States, Netherlands, France, Spain, United Kingdom, Germany, Argentina, Canada, Australia, Chile
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

Breast Cancer | Cognitive Impairments

United States
Sheffield Children's NHS Foundation Trust

Completed

Assessment of an Augmented Reality Low Visual Aid in Children and Young People With Visual Impairment

Vision Disability

United Kingdom
University of Western Sydney

Active, not recruiting

Computer-based Cognitive Rehabilitation Program for Healthy Older Adults, Older People With Mild Cognitive Impairment and Mild Dementia

Mild Cognitive Impairment | Mild Dementia | Healthy Older Adults

Australia
Clemson University
University of Alabama at Birmingham; National Institute on Aging (NIA); Penn...

Recruiting

Elucidating the Necessary Active Components of Training (ENACT)

Cognitive Impairment | Cognitive Change | Alzheimer Disease

United States
Woolcock Institute of Medical Research

Recruiting

Digital Sleep Therapy for Older Adults With Cognitive Impairment (ExCEED)

Cognitive Impairment | Insomnia Type; Sleep Disorder

Australia
Medical University of South Carolina
National Center for Advancing Translational Sciences (NCATS)

Completed

SUPPORT-D Intervention for Persons With Alzheimer's Disease and Their Caregivers

Alzheimer Disease | Mild Cognitive Impairment

United States
Medical University of South Carolina
National Cancer Institute (NCI)

Recruiting

Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site RCT (BRIGHT)

Head and Neck Cancer | Body Image Disturbance | Body Image | Psychosocial Impairment | Survivorship | Mental Health Issue

United States
Memory Pharmaceuticals

Unknown

Study to Evaluate the Safety and Efficacy of MEM 3454 as Adjunctive Treatment in Combination With a Preexisting Antipsychotic in Patients With Cognitive Impairment Associated With Schizophrenia

Cognitive Impairment Associated With Schizophrenia

United States
Atridia Pty Ltd.

Not yet recruiting

A Trial of SHR-1707 Infusion in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease and Mild Alzheimer's Disease

Alzheimer's Disease (AD)

Australia
Cochlear

Recruiting

A Feasibility Study Evaluating the Performance of Focused Multipolar Stimulation in Adult Cochlear Implant Recipients (FOCUS)

Hearing Impairment

Australia
University of Sydney

Active, not recruiting

Sleep Disturbance in MCI: A Study of a Cognitive Behavioural Therapy Digital Intervention (SUCCEED)

Sleep Wake Disorders | Insomnia | Cognitive Dysfunction | Mild Cognitive Impairment | Cognitive Disorder

Australia
Medical University of South Carolina
Michael J. Fox Foundation for Parkinson's Research

Completed

Atomoxetine Treatment for Cognitive Impairment in Parkinson's Disease (ATM-Cog) (ATM-Cog)

Parkinson's Disease | Cognitive Impairment

United States
University of Southern California
National Institute on Aging (NIA); Northern California Institute of Research... and other collaborators

Completed

Alzheimer's Disease Neuroimaging Initiative 2 (ADNI2)

Mild Cognitive Impairment (MCI) | Alzheimer's Disease (AD) | Significant Memory Concern (SMC) | Early Mild Cognitive Impairment (EMCI) | Late Mild Cognitive Impairment (LMCI)

United States, Canada
University of South Florida
National Institute on Aging (NIA); University of Florida; University of California... and other collaborators

Recruiting

The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia

Dementia | Mild Cognitive Impairment | Age-related Cognitive Decline

United States
VA Office of Research and Development

Completed

Blast Exposed Veterans With Auditory Complaints

Hearing Impairment | Hearing Aid Fitting

United States
University of Southern California
National Institute on Aging (NIA); Alzheimer's Therapeutic Research Institute; Wake Forest University Health Sciences

Completed

The Study of Nasal Insulin in the Fight Against Forgetfulness (SNIFF)

Alzheimer's Disease | Amnestic Mild Cognitive Impairment

United States
Amgen

Completed

Study of Romosozumab (AMG 785) Administered to Healthy Participants and Patients With Stage 4 Renal Impairment or Stage 5 Renal Impairment Requiring Hemodialysis

Osteoporosis

United States
Amgen

Completed

Multiple Dose Study to Evaluate the Safety of Multiple Doses of Denosumab 120 mg in Adults With Severe Chronic Kidney Disease (CKD) and CKD on Dialysis

Renal Impairment

United States
Actinogen Medical
Avance Clinical

Completed

A Double-Blind, Placebo-Controlled, Dose Ranging Study of Xanamem® in Healthy Elderly Volunteers (XanaMIA-DR)

Mild Cognitive Impairment | Alzheimer's Disease

Australia
Jaeb Center for Health Research
National Eye Institute (NEI); Genentech, Inc.; National Institutes of Health... and other collaborators

Recruiting

Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy (AL)

Visual Impairment | Radiation Retinopathy

United States
Takeda
Zinfandel Pharmaceuticals Inc.

Terminated

Biomarker Qualification for Risk of Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease (AD) and Safety and Efficacy Evaluation of Pioglitazone in Delaying Its Onset (TOMMORROW)

Mild Cognitive Impairment Due to Alzheimer's Disease

United States, Germany, Switzerland, United Kingdom, Australia
Woolcock Institute of Medical Research
National Health and Medical Research Council, Australia

Enrolling by invitation

The Effect of OSA on Brain Waste Clearance

Cognitive Impairment | Obstructive Sleep Apnea | Dementia

Australia
Allon Therapeutics

Completed

Study to Evaluate Safety, Tolerability, and Effect of AL208 on Mild Cognitive Impairment Following Coronary Artery Bypass Graft Surgery

Mild Cognitive Impairment

United States, Canada
Actinogen Medical
AXIOM Real Time Metrics

Active, not recruiting

Xanamem® in Adults With Major Depressive Disorder and Impaired Cognition (XanaCIDD)

Cognitive Impairment | Major Depressive Disorder | MDD

Australia, United Kingdom
Macquarie University, Australia
Life Molecular Imaging GmbH; Omniscient Neurotechnology

Active, not recruiting

Tau And Connectomics In TES Study (TACIT)

Neurodegenerative Diseases | Cognitive Impairment | Head Injury Trauma | Chronic Traumatic Encephalopathy | Traumatic Encephalopathy

Australia
Takeda

Terminated

AD-4833/TOMM40_303 Extension Study of the Safety and Efficacy of Pioglitazone to Slow Cognitive Decline in Participants With Mild Cognitive Impairment Due to Alzheimer Disease

Mild Cognitive Impairment Due to Alzheimer's Disease

United States, Australia, United Kingdom, Switzerland
CSL Behring

Completed

A Study of CSL112 in Adults With Moderate Renal Impairment and Acute Myocardial Infarction

Acute Myocardial Infarction | Moderate Renal Impairment

United States, Germany, Hungary, Israel, Netherlands
Eisai Inc.

Completed

A 28-Week Open Label Extension Study Evaluating Safety and Tolerability of Donepezil Hydrochloride in Subjects With Mild Cognitive Impairment

Mild Cognitive Impairment

United States
Inmune Bio, Inc.

Recruiting

A Study of XPro1595 in Patients With Early Alzheimer's Disease With Biomarkers of Inflammation (MINDFuL)

Mental Disorders | Brain Diseases | Central Nervous System Diseases | Nervous System Diseases | Neurocognitive Disorders | Neurodegenerative Diseases | Dementia | Alzheimer Disease | Tauopathies | Mild Cognitive Impairment

Australia, Canada, United Kingdom, Poland, Germany
Biogen

Recruiting

A Study to Learn About the Safety of BIIB080 and Whether it Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age (CELIA)

Mild Cognitive Impairment Due to Alzheimer's Disease | Alzheimer's Disease Dementia

Belgium, United States, Australia, Italy, Spain, Denmark, United Kingdom, Czechia, France, Poland, Germany, Canada, Japan, Finland, Switzerland, Netherlands, Sweden
Neuroscience Trials Australia
The Florey Institute of Neuroscience and Mental Health

Active, not recruiting

Deferiprone to Delay Dementia (The 3D Study)

Mild Cognitive Impairment | Prodromal Alzheimer's Disease | Mild Alzheimer's Disease

Australia

Clinical Trials on Airway Clearance Impairment in South Africa

Sponsors and Collaborators

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CROs in Bulgaria

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