Clinical Trials on Asymptomatic Necrotic Teeth in United States

Total 2447 results

PhotoThera, Inc

Completed

Effectiveness and Safety Trial of a New Ischemic Stroke Treatment Within 24 Hours From Stroke Onset (NEST-2)

Ischemic Stroke

United States, Germany, Peru, Sweden
AbbVie

Active, not recruiting

A Safety and Efficacy Study of Intravenous (IV) Elezanumab Assessing Change in Neurologic Function in Adult Participants With Acute Ischemic Stroke

Acute Ischemic Stroke

United States, Australia, Canada, Japan, Korea, Republic of, Spain
Shionogi

Recruiting

A Phase 2b, Randomized, Double-blind Study of Redasemtide (S-005151) in Adult Participants With Acute Ischemic Stroke (REvive)

Acute Ischemic Stroke

Japan, Israel, United States, Australia, Hong Kong
Imperial College London
Guy's and St Thomas' NHS Foundation Trust; University Hospital Southampton... and other collaborators

Recruiting

Intervention With Cerebral Embolic Protection in TEVAR: Gaseous Protection (INTERCEPT:GP)

Stroke | Neurocognitive Dysfunction | Silent Cerebral Infarction | Vascular Brain Injury

United Kingdom
Royal Surrey County Hospital NHS Foundation Trust
Kyowa Hakko Kirin UK, Ltd.

Completed

Study of Opioid-Induced Constipation 1 Project (StOIC-1)

Cancer | Opioid-induced Constipation | Cancer Pain

United Kingdom
Atox Bio Ltd
Biomedical Advanced Research and Development Authority

Completed

Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections (ACCUTE)

Necrotizing Fasciitis | Necrotizing Soft Tissue Infections | Fournier's Gangrene

United States, France
Royal Surrey County Hospital NHS Foundation Trust
Kyowa Hakko Kirin UK, Ltd.

Completed

Study of Opioid-Induced Constipation 2 Project (StOIC-2)

Cancer | Opioid-induced Constipation | Cancer Pain

United Kingdom
AstraZeneca

Completed

Assessment of Long-term Safety in Patients With Non-cancer-related Pain and Opioid-induced Constipation

Opioid-Induced Constipation (OIC)

United States
Leigh R. Hochberg, MD, PhD.
National Institute of Neurological Disorders and Stroke (NINDS); US Department... and other collaborators

Recruiting

BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia (BrainGate2)

Amyotrophic Lateral Sclerosis | Muscular Dystrophy | Spinal Cord Injuries | Tetraplegia | Brain Stem Infarctions | Locked in Syndrome

United States
Shionogi

Completed

A Study of Naldemedine (S-297995) for the Treatment of Opioid-Induced Constipation in Adults With Non-Malignant Chronic Pain Receiving Opioid Therapy

Opioid-induced Constipation

United States
Cervical Artery Dissections and Ischemic Stroke...

Unknown

Looking For Genetic and Environmental Risk Factors and Therapeutic Aspects in Cervical Artery Dissections (CADISP)

Stroke | Brain Infarction | Cervical Artery Dissection

Argentina, Belgium, Finland, France, Germany, Italy, Switzerland, Turkey, United Kingdom
Bellerophon BCM LLC

Completed

IK-5001 for the Prevention of Remodeling of the Ventricle and Congestive Heart Failure After Acute Myocardial Infarction (PRESERVATION-1)

Congestive Heart Failure | Acute Myocardial Infarction | ST-Elevation Myocardial Infarction

United States, Spain, France, Belgium, Australia, Israel, Canada, Germany, Poland
University of Miami
Medical University of South Carolina; National Institute of Neurological Disorders... and other collaborators

Terminated

Albumin in Acute Ischemic Stroke Trial (ALIAS)

Ischemic Stroke

United States, Canada, Israel, Finland
AstraZeneca

Terminated

Assessment of Efficacy and Safety in Relieving Opioid-induced Constipation in Patients With Cancer-related Pain

Opioid-Induced Constipation

Croatia, United States, Bulgaria, United Kingdom, Poland, Romania, Belgium, Puerto Rico, Slovakia, Australia, South Africa, Czech Republic, Germany, Spain
University of California, Los Angeles
Université de Montréal

Withdrawn

Use of a Tonometer to Identify Epileptogenic Lesions During Pediatric Epilepsy Surgery

Stroke | Epilepsy | Tuberous Sclerosis | Sturge-Weber Syndrome | Focal Cortical Dysplasia | Hemimegalencephaly | Polymicrogyria | Rasmussen Encephalitis | Gliosis | Tumor, Brain

United States, Canada
University of California, San Francisco
National Institute on Aging (NIA)

Completed

Rural Dementia Caregiver Project

Depression | Stress, Psychological | Dementia | Dementia, Vascular | Loneliness | Self Efficacy | Dementia, Mixed | Health Care Utilization | Dementia Alzheimers | Dementia of Alzheimer Type | Social Isolation | Dementia, Multi-Infarct | Dementia, Lewy Body | Dementia in Parkinsons Disease | Dementia Frontal | Dementia... and other conditions

United States
Cubist Pharmaceuticals LLC
GlaxoSmithKline

Completed

Study 767905/008 Extension Study: Alvimopan for Treatment of Opioid-Induced Bowel Dysfunction in Cancer Pain Subjects

Cancer | Bowel Dysfunction

United States, France, Canada, Finland, Spain, Pakistan, Poland, Hong Kong, United Kingdom, Peru, New Zealand, Portugal, Russian Federation
Janssen Pharmaceutica N.V., Belgium

Completed

A Study of Guselkumab in Participants With Active Psoriatic Arthritis and an Inadequate Response to Anti-Tumor Necrosis Factor Alpha (Anti-TNF Alpha) Therapy (COSMOS)

Arthritis, Psoriatic

Belgium, France, Israel, Italy, Germany, Bulgaria, Spain, Poland, Russian Federation, United Kingdom, Ukraine, Hungary, Portugal, Greece
Janssen Pharmaceutica N.V., Belgium

Completed

A Study on Assessment of STELARA and Tumor Necrosis Factor Alpha Inhibitor Therapies in Participants With Psoriatic Arthritis (PsaBio)

Psoriatic Arthritis

France, United Kingdom, Belgium, Spain, Netherlands, Greece, Russian Federation
University College, London
Wellcome Trust

Unknown

Differential Effects of Lipids on Cardiovascular Diseases: A CALIBER Study

ST Elevation Myocardial Infarction | Stable Angina | Unstable Angina | Non ST Elevation Myocardial Infarction | Myocardial Infarction Not Otherwise Specified

United Kingdom
Neurobiological Technologies

Terminated

ASP-II: Ancrod Stroke Program: Ancrod (Viprinex™) for the Treatment of Acute, Ischemic Stroke

Stroke | Brain Infarction | Cerebral Ischemia

United States, Australia, Israel, South Africa, Slovakia, New Zealand, Austria, Czech Republic, Poland, Russian Federation, Switzerland
Bausch Health Americas, Inc.

Completed

Study Evaluating Oral MOA-728 for the Treatment of Opioid-Induced Bowel Dysfunction (OIBD) in Subjects With Chronic Non-Malignant Pain

Constipation

United States
Sheffield Hallam University
AstraZeneca; Belfast Health and Social Care Trust; Sheffield Teaching Hospitals... and other collaborators

Recruiting

Optimising Secondary Prevention and Quality of Life in Early Cardiac Rehabilitation (OSPREY-CR)

Myocardial Infarction | Cardiovascular Diseases | Coronary Artery Disease | Heart Failure | Coronary Heart Disease | Acute Coronary Syndrome

United Kingdom
Western Sydney Local Health District

Recruiting

Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction (PROTECT-ICD) (PROTECT-ICD)

Sudden Cardiac Death

Australia, Switzerland, United States, New Zealand, Hungary, Czechia, Germany, Latvia, Malaysia, Poland, Russian Federation, Singapore, Slovakia, Greece, Israel
Purdue Pharma LP

Completed

A Study of Oxycodone/Naloxone Controlled-release Tablets (OXN) to Assess Analgesic Efficacy and Management of Opioid-induced Constipation (OIC) in Opioid-experienced Subjects With Moderate to Severe Chronic Low Back Pain

Low Back Pain

United States
AstraZeneca

Completed

Prevention of Cardiovascular Events (eg, Death From Heart or Vascular Disease, Heart Attack, or Stroke) in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin (PEGASUS)

Myocardial Infarction | Stroke | Atherothrombosis | Cardiovascular Death

Sweden, United States, Australia, Brazil, Bulgaria, Czech Republic, France, Italy, Korea, Republic of, Peru, Poland, Russian Federation, South Africa, Spain, Turkey, United Kingdom, Germany, Philippines, China, Hungary, Romania, U... and more
University of California, San Francisco
Zoll Medical Corporation

Completed

Vest Prevention of Early Sudden Death Trial and VEST Registry (VEST)

Myocardial Infarction | Ventricular Fibrillation | Ventricular Tachycardia | Ventricular Dysfunction | Sudden Death

United States, Germany, Poland
Imperial College London
Sanofi; Axtria, Inc.

Recruiting

OptimiZation Of Lipid Lowering Therapies Using a Decision Support System In Patients With Acute Coronary Syndrome. (ZODIAC)

Myocardial Infarction | Ischemic Stroke | Acute Coronary Syndrome

United Kingdom
Remedy Pharmaceuticals, Inc.

Terminated

Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric Infarction (CHARM)

Stroke, Acute | Brain Edema

United States, Spain, China, Italy, United Kingdom, Germany, Australia, Hungary, Taiwan, Israel, Canada, Portugal, Korea, Republic of, Czechia, Brazil, Switzerland, France, Belgium, Japan, Lithuania, Croatia, Denmark, Finland, Russian...
Oxford University Hospitals NHS Trust

Active, not recruiting

AI Assisted Reader Evaluation in Acute Computed Tomography (CT) Head Interpretation (AI-REACT)

Cerebral Infarction | Intracranial Hemorrhages | Acute Ischemic Stroke | Cerebral Edema | Hydrocephalus | Cerebral Injury

United Kingdom
AstraZeneca
Uppsala University

Completed

Dapagliflozin Effects on Cardiometabolic Outcomes in Patients With an Acute Heart Attack. (DAPA-MI)

Heart Failure | Acute Myocardial Infarction

Sweden, United Kingdom
AstraZeneca

Completed

A 30 Day Study to Evaluate Efficacy and Safety of Pre-hospital vs. In-hospital Initiation of Ticagrelor Therapy in STEMI Patients Planned for Percutaneous Coronary Intervention (PCI) (ATLANTIC)

Myocardial Infarction | Segment Elevation Myocardial Infarction (STEMI)

Australia, France, Italy, Spain, United Kingdom, Sweden, Germany, Hungary, Denmark, Austria, Canada, Netherlands, Algeria
University College, London
Wellcome Trust; National Institute for Health Research, United Kingdom

Unknown

Heart Rate and Cardiovascular Diseases Prognosis in People With Stable Coronary Artery Disease

Myocardial Infarction | Heart Failure | Stroke | Peripheral Arterial Disease | Atrial Fibrillation | Bleeding | Coronary Heart Disease | Stable Angina | Death, Sudden, Cardiac

United Kingdom
Bayer

Completed

Repinotan in Patients With Acute Ischemic Stroke

Stroke | Acute Ischemic Stroke

Germany, Italy, Spain, United States, Canada, Finland, France, Australia, Netherlands, Belgium, Hungary, Israel, Sweden, Austria, United Kingdom
Imperial College London
Imperial College Healthcare NHS Trust

Recruiting

INTERvention With Cerebral Embolic Protection in Transcatheter Aortic Valve Implantation (INTERCEPTavi) (INTERCEPTavi)

Stroke | Aortic Valve Stenosis | Silent Cerebral Infarct | Vascular Brain Injury

United Kingdom
University of Edinburgh
British Heart Foundation

Completed

In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer (iThrombus)

Myocardial Infarction | Stroke | Thrombosis | Transient Ischemic Attack | Pulmonary Embolism | STEMI | NSTEMI - Non-ST Segment Elevation MI | DVT | PET | Atherothrombosis | Prosthetic Valve Thrombosis

United Kingdom
University of Wisconsin, Madison
National Institute on Aging (NIA)

Recruiting

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study

CADASIL

United States
Sucampo Pharma Americas, LLC
Sucampo Pharmaceuticals, Inc.

Completed

Opioid-induced Bowel Dysfunction: Pivotal Assessment of Lubiprostone (OPAL)

Opioid-Induced Bowel Dysfunction

United States, Canada
Pulse Therapeutics

Suspended

Magnetically Enhanced Diffusion for Acute Ischaemic Stroke (MEDIS) Trial (MEDIS)

Cerebrovascular Disorders | Neurologic Disorder | Infarction, Middle Cerebral Artery | Stroke, Ischemic | Stroke, Acute | Intracranial Embolism and Thrombosis | Strokes Thrombotic

United Kingdom
LumiraDx UK Limited

Completed

Evaluation of Precision and Accuracy of INR Measurements in a Point of Care Device (OPTIMAL) (OPTIMAL)

Atrial Fibrillation | Thrombophilia | Deep Vein Thrombosis | Antiphospholipid Syndrome | Pulmonary Embolism | Post-Myocardial Infarction Syndrome | Artificial Heart Device User

United Kingdom
Brigham and Women's Hospital
Oregon Health and Science University; Vanderbilt University; Geisinger Clinic

Completed

Improving Quality by Maintaining Accurate Problems in the EHR (IQ-MAPLE)

Myocardial Infarction | Coronary Artery Disease | Smoking | Stroke | Hypertension | Chronic Obstructive Pulmonary Disease | Atrial Fibrillation | Asthma | Tuberculosis | Sleep Apnea | Sickle Cell Disease | Hyperlipidemia | Congestive Heart Failure

United States
The Royal Wolverhampton Hospitals NHS Trust

Completed

The Effect of IV Cangrelor and Oral Ticagrelor Study

ST-segment Elevation Myocardial Infarction (STEMI) | Acute Coronary Syndrome (ACS) | Unstable Angina (UA) | High On-treatment Platelet Reactivity (HTPR) | Microvascular Obstruction (MVO) | Thrombolysis in Myocardial Infarction (TIMI)

United Kingdom
Abbott Medical Devices
Cardiovascular Research Foundation, New York

Active, not recruiting

Evaluation of Treatment Strategies for Severe CaLcIfic Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting StEnts: The ECLIPSE Trial (ECLIPSE)

Coronary Artery Disease | Ischemic Heart Disease | Non ST Segment Elevation Myocardial Infarction

United States
University of Nottingham
National Institute for Health Research, United Kingdom

Completed

Validation and Reliability Testing of Dysphagia Trained Nurse Assessment

Dysphagia Following Cerebral Infarction | Dysphagia Following Nontraumatic Intracerebral Hemorrhage

United Kingdom
Sucampo Pharma Americas, LLC
Sucampo Pharmaceuticals, Inc.

Completed

Opioid-induced Bowel Dysfunction Pivotal Assessment of Lubiprostone (OPAL)

Opioid-Induced Bowel Dysfunction

United States, Canada
Sucampo Pharma Americas, LLC

Completed

Opioid-induced Bowel Dysfunction: Long-Term Assessment of Lubiprostone

Opioid-Induced Bowel Dysfunction

United States, Canada
AstraZeneca

Terminated

Long-Term rIsk, Clinical manaGement and Healthcare Resource Utilization of Stable CAD in Post MI Patients (TIGRIS)

Stable Coronary Artery Disease (CAD), Myocardial Infarction

United States, France, Italy, Spain, Turkey, United Kingdom, Germany, China, Romania, Finland, Netherlands, Norway, Canada, Mexico, Argentina, Australia, Belgium, Denmark, Portugal, Korea, Republic of, India, Japan, Brazil, Colombia, Ve...
Janssen Research & Development, LLC
Bayer

Completed

A Study to Assess the Effectiveness and Safety of Rivaroxaban in Reducing the Risk of Death, Myocardial Infarction or Stroke in Participants With Heart Failure and Coronary Artery Disease Following an Episode of Decompensated Heart Failure (COMMANDER HF)

Coronary Artery Disease | Heart Failure

United States, France, Poland, Ukraine, United Kingdom, China, Germany, Spain, Argentina, Mexico, Portugal, Bulgaria, Malaysia, Romania, Russian Federation, South Africa, Turkey, Korea, Republic of, Japan, Canada, Netherlands, Den... and more
Bellus Health Inc
FDA Office of Orphan Products Development

Completed

Study of the Safety and Efficacy of NC-503 in Secondary (AA) Amyloidosis

Gastrointestinal Diseases | Kidney Diseases | Rheumatoid Arthritis | Nephrotic Syndrome | Secondary (AA) Amyloidosis | Familial Mediterranean Syndrome

United States, Israel, Finland, France, Italy, Lithuania, Netherlands, Poland, Russian Federation, Spain, Turkey, United Kingdom
D-Pharm Ltd.

Terminated

Efficacy and Safety Study of DP-b99 in Treating Acute Ischemic Stroke (MACSI)

Acute Ischemic Stroke

Spain, Korea, Republic of, Israel, United States, France, Canada, Brazil, South Africa, Netherlands, Czech Republic, Austria, Germany, Italy, Hungary, Poland, Portugal, Slovakia, Switzerland

Clinical Trials on Asymptomatic Necrotic Teeth in United States

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