Clinical Trials on brca1 Mutation Carrier
Total 3070 results
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German Breast GroupGlaxoSmithKline; Stemline Therapeutics, Inc.Not yet recruitingBRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | Hormone Receptor Positive HER-2 Negative Breast Cancer | Advanced or Metastatic Breast CancerGermany
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Hellenic Cooperative Oncology GroupActive, not recruitingProstate Cancer Recurrent | Prostate Cancer Metastatic | Mutation | Germline BRCA1 Gene Mutation | Germline BRCA2 Gene MutationGreece
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Mayo ClinicAllerganCompletedNeoplasms | Pain, Postoperative | Breast Cancer | Breast Diseases | BRCA1 Mutation | BRCA2 MutationUnited States
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European Organisation for Research and Treatment...AstraZenecaWithdrawnBRCA1 Mutation | BRCA2 Mutation | TNBC - Triple-Negative Breast Cancer
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)RecruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma | MLH1 Gene Mutation | RAD51C Gene Mutation | RAD51D Gene Mutation | BRIP1 Gene Mutation | PALB2 Gene Mutation | BARD1 Gene Mutation | MSH2 Gene Mutation | MSH6... and other conditionsUnited States
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Severance HospitalSamsung Medical Center; Changhua Christian Hospital; European Institute of OncologyCompletedRecurrence | Postoperative Complications | Breast Cancer | Breast Neoplasms | Surgery | Surgery--Complications | BRCA1 Mutation | BRCA2 MutationKorea, Republic of
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Institute of Cancer Research, United KingdomCancer Research UK; National Institute for Health Research, United KingdomRecruitingProstate Cancer | BRCA1 Mutation | BRCA2 MutationUnited Kingdom
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Memorial Sloan Kettering Cancer CenterActive, not recruitingScreening Breast MRI in Patients Who Are BRCA Mutation CarriersUnited States
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Cancer Research UKCompletedBreast Cancer | Ovarian Cancer | brca1 Mutation Carrier | brca2 Mutation CarrierUnited Kingdom
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Metastatic Malignant Neoplasm | Advanced Malignant Neoplasm | Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | PALB2 Gene Mutation | ATM Gene MutationUnited States
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Dana-Farber Cancer InstituteJohns Hopkins University; GlaxoSmithKline; Translational Breast Cancer Research...RecruitingBreast Cancer | Stage I Breast Cancer | Stage II Breast Cancer | HER2-negative Breast Cancer | Stage III Breast Cancer | Deleterious PALB2 Gene Mutation | Germline BRCA1 Gene Mutation | Germline BRCA2 Gene MutationUnited States
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Rana McKay, MDUniversity of California, San Diego; AstraZenecaRecruitingProstate Cancer | BRCA1 Mutation | BRCA2 Mutation | Prostatic Adenocarcinoma | High-Risk CancerUnited States
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Georgetown UniversityCompletedPancreatic Cancer | Breast Neoplasm | BRCA1 Mutation | BRCA2 Mutation | Prostate CarcinomaUnited States
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Marc Dall'Era, MDNational Cancer Institute (NCI); Janssen, LPRecruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Prostate Carcinoma | RAD51C Gene Mutation | BRIP1 Gene Mutation | ATM Gene Mutation | CHEK2 Gene Mutation | NBN Gene Mutation | RAD51 Gene Mutation | CDK12 Gene Mutation | CHEK1 Gene Mutation | DNA Damage Response Gene Mutation | DNA Repair Gene Mutation | FANCA Gene Mutation and other conditionsUnited States
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Qian QinJanssen, LP; UT Southwestern Comprehensive Cancer CenterNot yet recruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | BRIP1 Gene Mutation | PALB2 Gene Mutation | CHEK2 Gene Mutation | FANCA Gene Mutation | RAD51B Gene Mutation | RAD54L Gene Mutation | Metastatic Hormone-sensitive Prostate Cancer (mHSPC) | Deleterious HRR Gene Mutation
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National Cancer Institute (NCI)CompletedHereditary Breast and Ovarian Cancer Syndrome | Adult Solid Neoplasm | BRCA1 Mutation Carrier | BRCA2 Mutation CarrierUnited States
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Institut CurieCompletedWomen With BRCA1 Germline Deleterious MutationFrance
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European Institute of OncologyRecruitingBRCA1 Mutation | BRCA2 Mutation | Lobular Breast Carcinoma | Lobular in Situ Breast CarcinomaItaly
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Southwest Oncology GroupNational Cancer Institute (NCI)CompletedBRCA1 Gene Mutation | BRCA2 Gene Mutation | Recurrent Squamous Cell Lung Carcinoma | Stage IV Squamous Cell Lung Carcinoma AJCC v7 | BRIP1 Gene Mutation | PALB2 Gene Mutation | ATM Gene Mutation | ATR Gene Mutation | CHEK2 Gene Mutation | NBN Gene Mutation | RAD51 Gene Mutation | CHEK1 Gene Mutation | FANCA Gene... and other conditionsUnited States, Canada
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Alliance for Clinical Trials in OncologyNational Cancer Institute (NCI)Active, not recruitingDuctal Breast Carcinoma in Situ | BRCA1 Mutation Carrier | BRCA2 Mutation Carrier | Atypical Ductal Breast Hyperplasia | Lobular Breast Carcinoma in SituUnited States
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Catholic University of the Sacred HeartUnknownBRCA1 and BRCA2 Mutation Carrier and BRCAness PhenotypeItaly
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The Netherlands Cancer InstituteRadboud University Medical Center; Erasmus Medical Center; Dutch Cancer SocietyUnknownCardiovascular Diseases | Quality of Life | Cognitive Decline | BRCA1 Mutation | BRCA2 Mutation | Bone Mineral Density | Surgical Menopause | Menopause SurgicalNetherlands
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Igentify LtdSheba Medical CenterUnknown
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Hanyang University Seoul HospitalKorean Surgical Society; Korea Robot-Endoscopy Minimal Access Breast Surgery...CompletedBRCA1/2 Mutation | Breast-conserving SurgeryKorea, Republic of
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University of California, San FranciscoThe Bluefield Project to Cure Frontotemporal DementiaCompletedProgranulin Mutation CarriersUnited States
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AstraZenecaCompletedHER2-ve Metastatic Breast Cancer | Germline BRCA1/2 Mutations | Somatic BRCA1/2 MutationsItaly, Spain, Poland, Taiwan, Canada, France, Germany, Korea, Republic of, Hungary, Japan, Russian Federation, Turkey, United Kingdom, United States, Bulgaria
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University of MichiganCompletedWomen With BRCA 1 or BRCA 2 Mutation | Non-tested Female Family MembersUnited States
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Northwestern UniversityNational Cancer Institute (NCI)CompletedStage 0 Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Lobular Breast Carcinoma In Situ | Ductal Breast Carcinoma In Situ | BRCA1 Mutation Carrier | BRCA2 Mutation CarrierUnited States
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Leiden University Medical CenterUniversity Medical Center Groningen; Erasmus Medical CenterRecruitingBRCA1 Mutation | BRCA2 Mutation | Homologous Recombination Deficiency | Ovarian Neoplasm EpithelialNetherlands
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Alexandru EniuIuliu Hatieganu University of Medicine and PharmacyCompletedTo Determine the Prevalence, Penetrance of BRCA1 and BRCA2 Mutations in Romanian Womens With Breast or Ovarian CancerRomania
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Memorial Sloan Kettering Cancer CenterRecruitingBRCA1 Mutation | BRCA2 Mutation | APC Gene Mutation | MLH1 Gene Mutation | RAD51C Gene Mutation | RAD51D Gene Mutation | BRIP1 Gene Mutation | PALB2 Gene Mutation | PTEN Gene Mutation | ATM Gene Mutation | CHEK2 Gene Mutation | BARD1 Gene Mutation | MSH2 Gene Mutation | MSH6 Gene Mutation | PMS2 Gene Mutation | POLD1 Gene... and other conditionsUnited States
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Hubei Biological Medicine Industrial Technology...UnknownAdvanced Solid Tumors | HRD | BRCA MutationChina
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University of Southern CaliforniaNational Cancer Institute (NCI); California Breast Cancer Research ProgramCompletedStage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Ductal Breast Carcinoma in Situ | BRCA1 Mutation Carrier | BRCA2 Mutation Carrier | Lobular Breast Carcinoma in SituUnited States
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Women's College HospitalCanadian Institutes of Health Research (CIHR); London Health Sciences Centre; H. Lee Moffitt Cancer Center and Research Institute and other collaboratorsUnknownBreast Cancer | Ovarian Cancer | BRCA1 Gene Mutation | BRCA2 Gene MutationCanada
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University of WashingtonNational Cancer Institute (NCI); National Institute of Nursing Research (NINR)CompletedDuctal Breast Carcinoma in Situ | BRCA1 Mutation Carrier | BRCA2 Mutation Carrier | Atypical Ductal Breast Hyperplasia | Lobular Breast Carcinoma in Situ | Atypical Lobular Breast HyperplasiaUnited States
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PfizerMedivation, Inc.; Myriad Genetic Laboratories, Inc.TerminatedBreast Neoplasms | BRCA 1 Gene Mutation | BRCA 2 Gene MutationUnited States, Spain, United Kingdom, Germany, France
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Translational Research Center for Medical Innovation...Okayama University; Japanese Gynecologic Oncology Group (JGOG)RecruitingFallopian Tube Carcinoma | Peritoneal Carcinoma | Ovarian Carcinoma | BRCA1 and/or BRCA2 Variant CarriersJapan
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Erasmus Medical CenterRecruitingSeroma | BRCA1/2 Mutation | Bilateral Prophylactic Mastectomy | Pectoral FasciaNetherlands
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PfizerMedivation, Inc.CompletedBreast Neoplasms | BRCA 1 Gene Mutation | BRCA 2 Gene MutationKorea, Republic of, United States, Australia, Spain, Belgium, France, Ireland, Taiwan, Poland, Germany, Israel, Brazil, United Kingdom, Italy, Russian Federation, Ukraine
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AstraZenecaMerck Sharp & Dohme LLC; Myriad Genetic Laboratories, Inc.Active, not recruitingBreast Cancer Metastatic | BRCA 1 Gene Mutation | BRCA 2 Gene MutationItaly, Spain, United States, Czechia, Romania, France, Korea, Republic of, United Kingdom, Hungary, Japan, Peru, Poland, Russian Federation, Turkey, China, Taiwan, Bulgaria, Switzerland, Mexico
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Fox Chase Cancer CenterNational Cancer Institute (NCI)TerminatedBreast Cancer | BRCA1 MutationUnited States, Austria
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Northwestern UniversityNorthwestern Memorial Hospital; Saint Joseph Hospital, Chicago, IllinoisRecruitingBreast Cancer | BRCA MutationUnited States
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Assistance Publique - Hôpitaux de ParisUnknownBreast Neoplasms | BRCA1 Protein | BRCA2 Protein | TomosynthesisFrance
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Jiangxi Qingfeng Pharmaceutical Co. Ltd.UnknownBreast Cancer Metastatic | BRCA 1 Gene Mutation | BRCA 2 Gene MutationChina
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University Medical Center NijmegenActive, not recruitingOvarian Cancer | BRCA1 Gene Mutation | BRCA2 Gene MutationNetherlands
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Lei LiUnknownEpithelial Ovarian Cancer | BRCA1 Mutation | BRCA2 Mutation | Homologous Recombination Deficiency | Prognosis | ChineseChina
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Lei LiCompletedEpithelial Ovarian Cancer | BRCA1 Mutation | BRCA2 Mutation | Homologous Recombination Deficiency | Prognosis | Chinese | Homologous Recombination GenesChina
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Alliance for Clinical Trials in OncologyNational Cancer Institute (NCI); Austrian Breast & Colorectal Cancer Study...RecruitingNeoplasms | Breast Cancer | Breast Neoplasms | Breast Diseases | Breast Carcinoma | BRCA1 MutationUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)WithdrawnPancreatic Ductal Adenocarcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Homologous Recombination Deficiency | Stage IIA Pancreatic Cancer AJCC v8 | Stage IIB Pancreatic Cancer AJCC v8 | ATM Gene Mutation | Deleterious BRCA1 Gene... and other conditions
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Institute of Cancer Research, United KingdomRoyal Marsden NHS Foundation Trust; Cancer Research UK; Ronald and Rita McAulay...Active, not recruitingProstate Cancer in BRCA1 and BRCA2 CarriersUnited Kingdom