Clinical Trials on Epidemiology of Cardiovascular Risk in Czechia

Total 47 results

Charles University, Czech Republic

Terminated

Hyperinvasive Approach in Cardiac Arrest

Out-of Hospital Cardiac Arrest

Czechia
Brno University Hospital

Terminated

Biochemical Makers for Outcome After Pediatric out-of Hospital Cardiac Arrest (BIMOPECA)

Out-Of-Hospital Cardiac Arrest

Czechia
Medtronic BRC

Completed

Reveal® XT Performance Trial (XPECT)

Atrial Fibrillation | Risk of Cardiac Arrhythmias

Netherlands, Germany, Austria, Belgium, Canada, Czech Republic, Russian Federation, Slovakia
Faculty Hospital Kralovske Vinohrady

Completed

Aneurysmorrhaphy of Vascular Access for Haemodialysis (AVAH)

Patients With an Aneurysm of Native Vascular Access Indicated for Surgical Treatment

Czechia
Palacky University

Completed

Evaluation of Life Quality in Post Stroke Patients

Stroke | Quality of Life

Czechia
Elena Gurkova
University Hospital Olomouc

Recruiting

Factors Affecting the Quality of Life After Ischemic Stroke in Young Adults (FRAILTY)

Ischemic Stroke

Czechia
Clinical Hospital Centre Zagreb
European Society of Hypertension

Unknown

Blood Pressure Control in ESH Excellence Centres (BP-CON)

White Coat Hypertension | Blood Pressure | Lifestyle Risk Reduction

Israel, Greece, Belgium, Germany, Armenia, Austria, Bulgaria, Croatia, Czechia, Estonia, Italy, Lebanon, Lithuania, Netherlands, Poland, Portugal, Romania, Serbia, Spain, Sweden, Ukraine, United Kingdom
University Hospital Ostrava
University of Ostrava

Recruiting

Improving the Quality of Life of Stroke Patients Using the Armeo Spring Device

Ischemic Stroke

Czechia
Mgr. Eliška Vrátná
Vladimíra Fejfarová, MD, PhD; prof. Ing. Václav Bunc, CSc

Unknown

Musculoskeletal Changes After Physiotherapeutic Intervention in Podiatric Subjects (BIONEDIAN)

Prevention of Diabetic Foot

Czechia
The Medicines Company

Completed

Inclisiran for Subjects With ASCVD or ASCVD-Risk Equivalents and Elevated Low-density Lipoprotein Cholesterol (ORION-11)

Risk Factor, Cardiovascular | Elevated Cholesterol | ASCVD

Germany, Czechia, Hungary, Poland, South Africa, Ukraine, United Kingdom
Sanofi
Bristol-Myers Squibb

Completed

Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events (ACTIVE A)

Atrial Fibrillation | Vascular Risk

United States, France, Canada, Brazil, Poland, Australia, Germany, Italy, Netherlands, Portugal, Spain, Sweden, Switzerland, Malaysia, Singapore, Taiwan, Belgium, Czech Republic, Mexico, Argentina, Denmark, Finland, Hungary, Norway, United... and more
Sanofi
Bristol-Myers Squibb

Terminated

Atrial Fibrillation Clopidogrel Trial With Irbesartan for Prevention of Vascular Events (ACTIVE W)

Atrial Fibrillation | Vascular Risk

United States, France, Canada, Brazil, Poland, Russian Federation, Australia, Germany, Italy, Netherlands, Portugal, Spain, Sweden, Switzerland, Turkey, Malaysia, Singapore, Taiwan, Belgium, Czech Republic, Mexico, Denmark, Finland, H... and more
Novo Nordisk A/S
Duke Clinical Research Institute

Not yet recruiting

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack (ARTEMIS)

Cardiovascular Risk | Acute Myocardial Infarction (AMI)

Canada, China, United States, Germany, Spain, Korea, Republic of, Netherlands, Australia, Italy, Denmark, India, United Kingdom, Argentina, Turkey, Mexico, Malaysia, Czechia, Poland, Brazil, France, Japan, Bulgaria, Greece, Israel
Charles University, Czech Republic

Unknown

AMAZING PRAGUE (PRAGUE-12) (AmP)

Atrial Fibrillation | Restore of Sinus Rhythm | Post-Operative Complications

Czech Republic
AstraZeneca
The Cleveland Clinic; IQVIA RDS Inc.

Completed

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia (STRENGTH)

Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)

United States, Belgium, Italy, Netherlands, Denmark, Taiwan, Poland, Russian Federation, Korea, Republic of, Hungary, United Kingdom, China, New Zealand, Czechia, Australia, South Africa, Ukraine, Japan, Canada, Mexico, Lithuania, Estoni...
Janssen Research & Development, LLC
The George Institute for Global Health, Australia

Completed

CANVAS - CANagliflozin cardioVascular Assessment Study (CANVAS)

Cardiovascular Diseases | Diabetes Mellitus, Type 2 | Risk Factors

United States, Australia, Poland, Ukraine, United Kingdom, Belgium, Germany, France, Spain, Argentina, Colombia, Israel, Mexico, India, Canada, Netherlands, Sweden, Malaysia, New Zealand, Estonia, Russian Federation, Hungary, Norway, ... and more
ECRI bv
University of Bern; European Cardiovascular Research Center; Terumo Medical Corporation and other collaborators

Completed

Management of High Bleeding Risk Patients Post Bioresorbable Polymer Coated Stent Implantation With an Abbreviated Versus Prolonged DAPT Regimen (MASTER DAPT)

Coronary Artery Disease | PCI | High Bleeding Risk

Netherlands, France, United Kingdom, Australia, Singapore, Japan, Italy, Poland, Spain, Switzerland, Israel, Argentina, Austria, Bahrain, Bangladesh, Belgium, Bulgaria, Czechia, Denmark, Estonia, Germany, Hungary, India, Korea, Republic... and more
Idorsia Pharmaceuticals Ltd.

Completed

Tezosentan in the Treatment of Acute Heart Failure (VERITAS 2)

Acute Heart Failure | Acute Decompensation of Chronic Heart Failure | New Onset of Heart Failure

United States, Hungary, Australia, Czechia, Germany, Italy, Norway, United Kingdom
University College Cork
Institut National de la Santé Et de la Recherche Médicale, France; KU Leuven; University of Alberta and other collaborators

Terminated

Management of Hypotension In the Preterm Infant (HIP)

Hypotension | Low Blood Pressure | Intraventricular Hemorrhage of Prematurity

Canada, Ireland, Belgium, Czechia, United Kingdom
Niklas Nielsen
Lund University; The George Institute for Global Health, Australia; Copenhagen... and other collaborators

Completed

Target Temperature Management After Cardiac Arrest (TTM)

Out-of-hospital Cardiac Arrest

Sweden, Netherlands, Norway, United Kingdom, Italy, Australia, Switzerland, Luxembourg, Czech Republic, Denmark
Ablynx, a Sanofi company

Completed

Comparative Study of ALX-0081 Versus GPIIb/IIIa Inhibitor in High Risk Percutaneous Coronary Intervention (PCI) Patients

Unstable Angina | Non ST Segment Elevation Myocardial Infarction (NSTEMI) | Stable Angina (Associated With High Risk PCI)

Poland, Belgium, Germany, Israel, Austria, Switzerland, Czechia
Boehringer Ingelheim

Completed

Treatment of Patients Undergoing Primary Unilateral Elective Total Knee or Hip Replacement With Dabigatran Etexilate

Arthroplasty, Replacement | Prevention of Venous Thromboembolism | Moderate Renal Impairment (CrCl 30-50 mL/Min)

Austria, Canada, Czechia, Finland, Netherlands, Sweden
Bayer

Recruiting

A Study to Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After a High-risk Transient Ischemic Attack, a So-called Mini Stroke (OCEANIC-STROKE)

Acute Non-cardioembolic Ischemic Stroke | Prevention of Ischemic Stroke | High-risk Transient Ischemic Attack

United States, Switzerland, Belgium, Sweden, Canada, Australia, Taiwan, Spain, Korea, Republic of, Latvia, Israel, Malaysia, Greece, Japan, Turkey, Netherlands, Romania, China, United Kingdom, Portugal, Italy, Brazil, France, Slovakia, ... and more
Ferring Pharmaceuticals

Completed

An Open-Label, Multi-centre, Phase III Study of Local Tolerability of ZOMACTON 10MG

Turner's Syndrome

Czech Republic, France, Netherlands
Helsingborgs Hospital
Lund University; Region Skåne - Skånevård SUND; Copenhagen Trial Unit, Center... and other collaborators

Completed

Targeted Hypothermia Versus Targeted Normothermia After Out-of-hospital Cardiac Arrest (TTM-2)

Out-of-hospital Cardiac Arrest

Norway, Sweden, Denmark, France, New Zealand, United Kingdom, Belgium, United States, Australia, Austria, Czechia, Germany, Italy, Switzerland
Kips Bay Medical, Inc.

Unknown

The eMESH 1 Feasibility Study (eMESH 1)

Atherosclerosis of Autologous Vein Coronary Artery Bypass Graft(s)

United States, United Kingdom, Czech Republic, Netherlands, France, Italy, Switzerland
National Institute of Cardiology, Warsaw, Poland

Recruiting

Drug-coated Balloon in de Novo Chronic Total Occlusions (CTO-DENOVO)

Coronary Artery Disease | Total Occlusion of Coronary Artery

Spain, France, Hungary, Czechia, Poland, Austria, Croatia, Germany, Israel, Italy, Romania
Centre Chirurgical Marie Lannelongue
Easy-CRF

Recruiting

European Multicentre Registry of Percutaneous Paravalvular Leak Closure (EuroPVL)

Quality of Life | Cardiac Valve Disease | Outcomes | Paravalvular Aortic Regurgitation | Paravalvular Mitral Regurgitation | Paravalvular Leak

Belgium, France, Poland, United Kingdom, Czechia, Greece, Italy, Latvia, Lithuania, Mexico, Spain, Turkey
AstraZeneca
Bristol-Myers Squibb; Hadassah Medical Organization; The TIMI Study Group

Completed

Multicenter Trial to Evaluate the Effect of Dapagliflozin on the Incidence of Cardiovascular Events (DECLARE-TIMI58)

Diabetes Mellitus, Non-Insulin-Dependent | High Risk for Cardiovascular Event

United States, Canada, France, Italy, Netherlands, Spain, Belgium, Thailand, Vietnam, Bulgaria, Korea, Republic of, Brazil, Philippines, Russian Federation, Turkey, Taiwan, Australia, Israel, South Africa, Germany, Japan, Czechia, H... and more
Supernus Pharmaceuticals, Inc.
Solstice Neurosciences

Active, not recruiting

Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity

Multiple Sclerosis | Cerebral Palsy | Traumatic Brain Injury | Cerebrovascular Accident | Cervical Spinal Cord Injury | Spasticity

United States, Czechia
Novo Nordisk A/S

Recruiting

ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease and Inflammation (ZEUS)

Inflammation | Chronic Kidney Disease | Cardiovascular Risk

Korea, Republic of, Italy, United States, Spain, China, Taiwan, Mexico, Netherlands, Latvia, Malaysia, Thailand, Hungary, Australia, Poland, South Africa, India, Canada, Portugal, Romania, United Kingdom, Bulgaria, Germany, Brazil, Sw... and more
Novartis Pharmaceuticals

Recruiting

A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.

Primary Prevention of Atherosclerotic Cardiovascular Disease

United States, China, Italy, Spain, Canada, France, Netherlands, Switzerland, Taiwan, Greece, Thailand, Brazil, India, Hungary, Latvia, Mexico, Israel, Turkey, Argentina, Singapore, Australia, Belgium, Bulgaria, Denmark, Croatia, South Africa and more
Merck KGaA, Darmstadt, Germany
Merck Serono S.A., Geneva

Completed

First Year Growth Response Associated Genetic Markers Validation Phase IV Open-label Study in Growth Hormone Deficient and Turner Syndrome Pre-pubertal Children: the PREDICT Pharmacogenetics Validation Study

Turner Syndrome | Idiopathic Growth Hormone Deficiency

Spain, France, Canada, United Kingdom, Czech Republic, Argentina, Germany, Italy, Sweden
Ipsen

Completed

Study to Define Optimal IGF-1 Monitoring in Children Treated With NutropinAq (OPTIMA)

Renal Insufficiency, Chronic | Pituitary Diseases | Dwarfism | Turner Syndrome

France, Germany, Finland, Spain, Belgium, Czechia, Denmark, Greece, Italy, Romania, Russian Federation, Slovakia, Ukraine, United Kingdom
Olympus Biotech Corporation

Completed

The TRAfermin in Neuropathic Diabetic Foot Ulcer Study - Southern Europe The TRANS-South Study (TRANS-South)

Diabetic Foot Ulcer of Neuropathic Origin

France, Italy, Hungary, Czech Republic
Actelion

Terminated

Persistent Pulmonary Hypertension of the Newborn (FUTURE 4)

Persistent Pulmonary Hypertension of the Newborn

United States, Australia, Belgium, Czech Republic, France, Germany, Korea, Republic of, Poland, Russian Federation, Singapore, Switzerland, United Kingdom
Pharvaris Netherlands B.V.

Recruiting

Extension Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema (RAPIDe-2)

Hereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | Hereditary Angioedema Types I and II | Hereditary Angioedema Attack | Hereditary Angioedema With C1 Esterase Inhibitor Deficiency | Hereditary Angioedema - Type 1 | Hereditary Angioedema - Type 2 | C1 Esterase Inhibitor... and other conditions

United States, Bulgaria, Czechia, Hungary, Spain, France, Germany, Poland, Canada, Israel
Merz Pharmaceuticals GmbH

Completed

Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Spasticity in the Arm After a Stroke (PURE)

Post-stroke Spasticity of the Upper Limb

Poland, United States, Czech Republic, Germany, Hungary, India, Russian Federation
Novo Nordisk A/S

Completed

Observational Prospective Study on Patients Treated With Norditropin®

Chronic Kidney Disease | Turner Syndrome | Noonan Syndrome | Chronic Renal Insufficiency | Growth Hormone Disorder | Growth Hormone Deficiency in Children | Adult Growth Hormone Deficiency | Genetic Disorder | Foetal Growth Problem | Small for Gestational Age

Israel, Saudi Arabia, Spain, Argentina, Russian Federation, Germany, Netherlands, Italy, Belgium, United Kingdom, Slovenia, Ireland, Sweden, Denmark, Hungary, Finland, Norway, France, Czechia, Lithuania, Luxembourg, Serbia, Switzerland
Merz Pharmaceuticals GmbH

Completed

Efficacy and Safety Study of Botulinum Toxin Type A Against Placebo to Treat Spasticity in the Leg After a Stroke (PLUS)

Post-stroke Spasticity of the Lower Limb

Germany, Poland, Spain, United States, Czech Republic, Russian Federation, Canada, France, Italy
Cytokinetics

Completed

COSMIC-HF - Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure (COSMIC-HF)

Chronic Heart Failure | Pharmacokinetics | Left Ventricular Systolic Dysfunction | Left Ventricular Ejection Fraction | Modified Release Oral Formulation | History of Chronic Heart Failure | Echocardiogram

United States, Canada, Italy, Netherlands, United Kingdom, Belgium, Czechia, Australia, Hungary, Poland, Bulgaria, Lithuania, Germany
Bayer

Terminated

A Study to Learn How Well the Study Treatment Asundexian Works and How Safe it is Compared to Apixaban to Prevent Stroke or Systemic Embolism in People With Irregular and Often Rapid Heartbeat (Atrial Fibrillation), and at Risk for Stroke (OCEANIC-AF)

Atrial Fibrillation | Prevention of Stroke or Systemic Embolism

Canada, United States, Israel, Korea, Republic of, China, Taiwan, Belgium, Australia, Singapore, Malaysia, Slovakia, United Kingdom, Czechia, Latvia, Japan, Brazil, Lithuania, Germany, France, Sweden, Turkey, Switzerland, Estonia, Bul... and more
Novartis Pharmaceuticals

Recruiting

Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR) (REPLENISH)

Polymyalgia Rheumatica

United States, Australia, Germany, Belgium, France, Spain, Italy, Lebanon, Switzerland, Japan, Israel, Denmark, Argentina, Netherlands, Colombia, Chile, Hungary, Poland, Turkey, Czechia, Brazil, South Africa, Mexico, Canada, United Kingdom
Novartis Pharmaceuticals

Recruiting

Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Giant Cell Arteritis (GCA)

Giant Cell Arteritis (GCA)

United States, Israel, Spain, Turkey, France, Hungary, Belgium, Germany, Argentina, Chile, Greece, Portugal, Bulgaria, Italy, Switzerland, Australia, Czechia, Denmark, Austria, Brazil, Guatemala, United Kingdom, Finland, Russian Federation and more
AbbVie

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of Upadacitinib in Participants With Giant Cell Arteritis (SELECT-GCA)

Giant Cell Arteritis (GCA)

United States, Australia, Austria, Belgium, Canada, Czechia, Denmark, France, Germany, Greece, Hungary, Israel, Italy, Japan, Netherlands, New Zealand, Norway, Portugal, Romania, Russian Federation, Spain, Sweden, Switzerland, United...
Bayer

Completed

Study to Investigate the Safety of a Drug Called Osocimab at Low and High Doses in Adult Patients With Kidney Failure Requiring Regular Hemodialysis (CONVERT)

Hemodialysis | End-stage Renal Disease | Hemodiafiltration | Prevention of Thromboembolic Events

Spain, Greece, Belgium, Russian Federation, Netherlands, Turkey, Japan, Australia, Austria, Bulgaria, Italy, Ukraine, Czechia, Israel, United States, Hungary, Lithuania, Poland, Portugal
University of Oxford
American College of Rheumatology; The European League Against Rheumatism (EULAR) and other collaborators

Unknown

American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) Diagnostic and Classification Criteria for Primary Systemic Vasculitis (DCVAS)

Giant Cell Arteritis | Wegener's Granulomatosis | Microscopic Polyangiitis | Polyarteritis Nodosa | Takayasu Arteritis | Churg Strauss Syndrome

Korea, Republic of, United States, Germany, Australia, Japan, Ireland, Belgium, Italy, Denmark, Slovenia, Switzerland, Canada, Argentina, Austria, China, Czech Republic, Egypt, Finland, France, Hungary, India, Mexico, Netherlands, New... and more

Clinical Trials on Epidemiology of Cardiovascular Risk in Czechia

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