Clinical Trials on Functional Dyspepsia in South Africa

Total 161 results

Prof Mags Beksinska

Completed

Functional Performance and Acceptability Study of Synthetic Nitrile, and Latex Graphene, Compared to Standard Latex Male Condom

Functional Performance

South Africa
Sheffield Teaching Hospitals NHS Foundation Trust

Recruiting

Traditional Dietary Advice Versus Low FODMAP Diet in Postprandial Functional Dyspepsia

Dyspepsia | Functional Gastrointestinal Disorders

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Recruiting

Traditional Dietary Advice Versus Reassurance-alone in Postprandial Functional Dyspepsia

Dyspepsia | Functional Gastrointestinal Disorders

United Kingdom
DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

South Africa
University of Stellenbosch
Nestlè Nutrition Institute Africa; National Research Foundation (NRF) (RSA)

Completed

Effect of Lactobacillus Plantarum 299v on Symptoms of Irritable Bowel Syndrome

Irritable Bowel Syndrome

South Africa
University of Witwatersrand, South Africa

Unknown

A Comparison of Immediate Treatment of CIN1 With Cryotherapy and 12 Month Cytology Follow up in HIV Seropositive Women

Cervical Dysplasia

South Africa
University of Witwatersrand, South Africa

Completed

Validation of Implementation of Cervical Dysplasia Treatment Modalities in HIV-Seropositive Women (VICAR2)

Cervical Intraepithelial Neoplasia

South Africa
Antiva Biosciences

Completed

Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection.

Cervical Cancer | Human Papilloma Virus | HSIL, High Grade Squamous Intraepithelial Lesions | Cervical Dysplasia | HSIL of Cervix | High-Grade Cervical Intraepithelial Neoplasia | HIV Negative | CIN - Cervical Intraepithelial Neoplasia | Cervical Neoplasm

South Africa
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Acceptability and Feasibility of Combination Treatment for Cervical Precancer Among South African Women Living With HIV (ACT2)

Cervical Cancer | Human Immunodeficiency Virus | Human Papillomavirus | CIN2 | CIN3

South Africa
University of Cape Town
Stanford University

Recruiting

Point-of-care Ultrasound Abnormalities in Early Onset Preeclampsia

Preeclampsia | Pulmonary Edema | Cardiac Function

South Africa
Antiva Biosciences

Recruiting

A Study of ABI-2280 Vaginal Tablet in Participants With Cervical Intraepithelial Neoplasia

Cervical Intraepithelial Neoplasia

Australia, South Africa
Zeria Pharmaceutical

Completed

The Effects of Z-338 in Subjects With and Without Functional Dyspepsia

Dyspepsia

Australia
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Acceptability and Tolerability of Magnetic Assisted Capsule Endoscopy Compared to Gastroscopy

Dyspepsia

United Kingdom
Unity Health Toronto

Completed

Transfusion Requirements in Cardiac Surgery III (TRICS-III)

Disorder; Heart, Functional, Postoperative, Cardiac Surgery

Canada, Spain, United States, Israel, Australia, New Zealand, Denmark, Colombia, Egypt, Germany, Singapore, Switzerland, China, Brazil, Greece, India, Malaysia, Romania, South Africa
Cardiac Dimensions Pty Ltd

Terminated

An Initial Evaluation of the Carillon Mitral Contour System for Treatment of Atrial Function Mitral Regurgitation (AFIRE)

Atrial Fibrillation | Functional Mitral Regurgitation | Atrial Functional Mitral Regurgitation

Australia, Greece
Medical University of South Carolina
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Individualizing tDCS Dose

tDCS | Motor Function

United States
Rutgers, The State University of New Jersey
Harokopio University

Completed

A Study of Chios Mastic Water in Irritable Bowel Syndrome (MASTIQUA)

Irritable Bowel Syndrome

Greece
GlaxoSmithKline

Completed

A Phase 1, First Time in Human (FTIH) Study to Evaluate GSK3352589, a REarranged During Transfection (RET) Growth Factor Receptor Tyrosine Kinase Inhibitor, in Healthy Volunteers

Irritable Bowel Syndrome

Australia
GlaxoSmithKline

Completed

A Phase I, Randomized, Placebo-controlled, Double Blind, Repeat Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Gastrointestinal Transit Time and Pharmacodynamic Biomarkers of GSK3179106 in Normal Subjects

Irritable Bowel Syndrome

Australia
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of California, Los Angeles; Merck... and other collaborators

Active, not recruiting

HPV Vaccine Therapy in Reducing High-Grade Cervical Lesions in Patients With HIV and HPV (COVENANT)

HIV Infection | AIDS-Related Human Papillomavirus Infection | High Grade Cervical Squamous Intraepithelial Neoplasia

Uganda, Kenya, Zimbabwe, South Africa, Malawi
GlaxoSmithKline

Completed

A Phase 1, Randomized, Placebo-Controlled, Ascending Cohort, Dose Escalation Study in Normal Healthy Volunteers

Irritable Bowel Syndrome

Australia
Sheffield Teaching Hospitals NHS Foundation Trust

Recruiting

Traditional Dietary Advice Vs. Mediterranean Diet in IBS

Irritable Bowel Syndrome

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

A Study Comparing the Effectiveness and Convenience of Dietary Therapy for Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome

United Kingdom
Aghia Sophia Children's Hospital of Athens
BioGaia AB

Completed

Efficacy of Dietary Supplementation With Lactobacilllus Reuteri DSM 17938 on Functional Abdominal Pain (FAP) in Children

Functional Abdominal Pain (FAP) in Children

Greece, Poland, Slovenia
The Hawkins Foundation

Completed

Hip Scope Fascia-iliaca (FI) Block Study

Acetabular Labrum Tear | Hip Dysplasia | Femoroacetabular Impingement

United States
Medical University of South Carolina

Completed

The Impact of Adjuvant Liquid Alginate on Endoscopic Ablation Therapy of Complicated Barrett's Esophagus

Barretts Esophagus With Dysplasia

United States
Sucampo Pharma Americas, LLC
Sucampo AG

Completed

Evaluation of the Safety of Lubiprostone in Pediatric Participants Aged ≥ 6 Years to < 18 Years With Functional Constipation

Constipation - Functional

United States
University of South Carolina
Centers for Disease Control and Prevention

Recruiting

Mindful Walking Program for Older African Americans

Cognitive Function | Behavior, Health | Aging Well

United States
RedHill Biopharma Limited

Completed

ERADICATE Hp2 - Treating Helicobacter Pylori With RHB-105 Compared to Active Comparator (ERADICATE Hp2)

Dyspepsia | Helicobacter Pylori Infection

United States
Virginia Commonwealth University
Medical University of South Carolina; Ochsner Health System

Withdrawn

Confocal Endomicroscopy for Non-Erosive Reflux Disease (CE NERD) (CE_NERD)

Dyspepsia | Gastroesophageal Reflux Disease | Non Erosive Reflux Disease

United States
Astellas Pharma Inc
Astellas Pharma US, Inc.

Completed

YM443 in Subjects With Functional Dyspepsia

Nausea | Indigestion

United States
Case Comprehensive Cancer Center

Terminated

Older Patients With Newly Diagnosed Breast Cancer or Colon Cancer

Breast Cancer | Colorectal Cancer | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment

United States
Anji Pharma
Covance

Completed

A Proof of Concept Study of Pradigastat in Patients With Functional Constipation

Functional Constipation

China, United States
Allergan
Ironwood Pharmaceuticals, Inc.

Completed

Linaclotide Safety and Efficacy in 2 to 5-Year-Old Participants With Functional Constipation

Functional Constipation

United States
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; University of Liverpool

Completed

Muscle in Obesity: Imaging, Function and microRNA

Muscle Function

United Kingdom
AstraZeneca

Completed

Nexium Dyspepsia/AST

Signs and Symptoms, Digestive | Dyspepsia | Gastrointestinal Disease

Sweden, Brazil, France, Italy, South Africa, Spain, Germany, Romania, Denmark, Norway, Canada, Argentina, Belgium, Greece, Iceland, Switzerland, Singapore
AbbVie
Ironwood Pharmaceuticals, Inc.

Recruiting

A Study to Assess Adverse Events and Change in Disease Activity in Pediatric Participants (Age 6 Months to <2 Years) With Functional Constipation Who Are Treated With Linaclotide

Functional Constipation

United States, Bulgaria, United Kingdom, Croatia, Germany, Hungary
Medical University of South Carolina
National Institute of Neurological Disorders and Stroke (NINDS); National Institutes...

Completed

Functional Viability Duck Duck Punch (DDPSBIR)

Stroke | Rehabilitation | Recovery of Function

United States
GlaxoSmithKline

Completed

A Study To Investigate GW427353 In Subjects With Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome (IBS)

Germany, Australia, France
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of PDR001 in Patients With Advanced or Metastatic, Well-differentiated, Non-functional Neuroendocrine Tumors of Pancreatic, Gastrointestinal (GI), or Thoracic Origin or Poorly-differentiated Gastroenteropancreatic Neuroendocrine Carcinoma (GEP-NEC)

Well-differentiated Non-functional NET of Thoracic Origin | Well-differentiated Non-functional NET of Gastrointestinal Origin | Well-differentiated Non-functional NET of Pancreatic Origin | Poorly-differentiated Gastroenteropancreatic Neuroendocrine Carcinoma

United States, Italy, Spain, Japan, Belgium, Netherlands, Germany, France, Canada, Austria, United Kingdom, Australia
AstraZeneca

Completed

Nexium Dyspepsia/AST

Signs and Symptoms, Digestive | Dyspepsia | Gastrointestinal Disease

Mexico, South Africa, United Kingdom, Hungary, Finland, Norway, Canada, Austria, France, Sweden, Germany, Belgium, Switzerland
Lucid Diagnostics, Inc.

Completed

Efficacy of EsoGuard on Samples Collected Using EsoCheck Versus EGD for the Diagnosis of BE (ESOGUARDBE1)

Barrett Esophagus | Esophageal Adenocarcinoma | Barrett's Esophagus Without Dysplasia | Barretts Esophagus With Dysplasia

United States, Spain
Prolong Pharmaceuticals

Completed

Efficacy and Safety of SANGUINATE™ for Reduction of Delayed Graft Function in Patients Receiving a Kidney Transplant

Delayed Function of Renal Transplant

United States
AbbVie
Ironwood Pharmaceuticals, Inc.

Enrolling by invitation

Long-term Safety of Linaclotide in Pediatric Participants With FC or IBS-C

Irritable Bowel Syndrome With Constipation | Functional Constipation

United States, Canada, Israel, Netherlands
Urovant Sciences GmbH

Completed

Study to Evaluate the Efficacy and Safety of Vibegron Administered Orally for 12 Weeks to Women With Irritable Bowel Syndrome

Irritable Bowel Syndrome

United States
Sucampo Pharma Americas, LLC
Takeda

Completed

Lubiprostone for Children With Constipation

Constipation - Functional

United States, United Kingdom, Netherlands, Poland, Belgium, France, Canada
GlaxoSmithKline

Completed

Eight-Weeks Of Treatment With Talnetant In Subjects With Irritable Bowel Syndrome (IBS)

Irritable Colon

United States, Spain, South Africa, Sweden, Australia, Canada, Germany, United Kingdom, France, Netherlands
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of DV890 in Patients With COVID-19 Pneumonia

COVID-19 Pneumonia, Impaired Respiratory Function

Germany, India, Spain, Russian Federation, Mexico, Netherlands, Peru, Brazil, Hungary, Argentina, Denmark, South Africa
Sucampo Pharma Americas, LLC
Sucampo AG

Completed

Lubiprostone in Children With Functional Constipation

Constipation - Functional

United States, United Kingdom, Canada, Netherlands, Poland, Belgium, France
AbbVie
Ironwood Pharmaceuticals, Inc.

Active, not recruiting

Linaclotide Safety and Efficacy in Pediatric Participants, 6 to 17 Years of Age, With Irritable Bowel Syndrome With Constipation (IBS-C) or Functional Constipation (FC) (LINZESS)

Irritable Bowel Syndrome With Constipation | Functional Constipation

United States, Belgium, Bulgaria, Canada, Estonia, Israel, Italy, Netherlands, Poland, Puerto Rico, Spain, Ukraine, United Kingdom, Germany

Clinical Trials on Functional Dyspepsia in South Africa

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