Clinical Trials on Functional Impairment in South Africa

Total 204 results

Prof Mags Beksinska

Completed

Functional Performance and Acceptability Study of Synthetic Nitrile, and Latex Graphene, Compared to Standard Latex Male Condom

Functional Performance

South Africa
University of Stellenbosch
Nestlè Nutrition Institute Africa; National Research Foundation (NRF) (RSA)

Completed

Effect of Lactobacillus Plantarum 299v on Symptoms of Irritable Bowel Syndrome

Irritable Bowel Syndrome

South Africa
Novartis Pharmaceuticals

Completed

A Phase l Study to Evaluate the Pharmacokinetics and Safety Pasireotide in Subjects With Varying Degrees of Renal Impairment Compared to Healthy Volunteers

Renal Impairment

Germany, South Africa
University of Cape Town
Stanford University

Recruiting

Point-of-care Ultrasound Abnormalities in Early Onset Preeclampsia

Preeclampsia | Pulmonary Edema | Cardiac Function

South Africa
Novartis Pharmaceuticals

Terminated

Effect of AQW051 in Patients With Memory Impairment

Amnestic Mild Cognitive Impairment | Mild Alzheimer's Disease

Canada, United Kingdom, South Africa
Unity Health Toronto

Completed

Transfusion Requirements in Cardiac Surgery III (TRICS-III)

Disorder; Heart, Functional, Postoperative, Cardiac Surgery

Canada, Spain, United States, Israel, Australia, New Zealand, Denmark, Colombia, Egypt, Germany, Singapore, Switzerland, China, Brazil, Greece, India, Malaysia, Romania, South Africa
Cardiac Dimensions Pty Ltd

Terminated

An Initial Evaluation of the Carillon Mitral Contour System for Treatment of Atrial Function Mitral Regurgitation (AFIRE)

Atrial Fibrillation | Functional Mitral Regurgitation | Atrial Functional Mitral Regurgitation

Australia, Greece
University of Vermont
Medical University of South Carolina; University of Washington; University of...

Active, not recruiting

Communication During Hospitalization About Resuscitation Trial (CHART)

End Stage Renal Disease | Severe Life-limiting COPD | Severe Life-limiting Heart Failure | Severe Life-limiting Cirrhosis | Severe Life-limiting Malignancy | Severe Functional Impairment

United States
Medical University of South Carolina
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Individualizing tDCS Dose

tDCS | Motor Function

United States
Rutgers, The State University of New Jersey
Harokopio University

Completed

A Study of Chios Mastic Water in Irritable Bowel Syndrome (MASTIQUA)

Irritable Bowel Syndrome

Greece
Novartis Pharmaceuticals

Completed

Single-dose Iloperidone Pharmacokinetics in Patients With Mild or Moderate Liver Disease, Compared to Healthy Volunteers

Hepatic Impairment

United States
GlaxoSmithKline

Completed

A Phase 1, First Time in Human (FTIH) Study to Evaluate GSK3352589, a REarranged During Transfection (RET) Growth Factor Receptor Tyrosine Kinase Inhibitor, in Healthy Volunteers

Irritable Bowel Syndrome

Australia
GlaxoSmithKline

Completed

A Phase I, Randomized, Placebo-controlled, Double Blind, Repeat Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Gastrointestinal Transit Time and Pharmacodynamic Biomarkers of GSK3179106 in Normal Subjects

Irritable Bowel Syndrome

Australia
GlaxoSmithKline

Completed

A Phase 1, Randomized, Placebo-Controlled, Ascending Cohort, Dose Escalation Study in Normal Healthy Volunteers

Irritable Bowel Syndrome

Australia
Cochlear
Avania

Completed

CP1150 Sound Processor Speech Perception Compared With the Next Generation of Signal Processing Technology

Hearing Impairment, Sensorineural

Australia
Sheffield Teaching Hospitals NHS Foundation Trust

Recruiting

Traditional Dietary Advice Versus Low FODMAP Diet in Postprandial Functional Dyspepsia

Dyspepsia | Functional Gastrointestinal Disorders

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Recruiting

Traditional Dietary Advice Versus Reassurance-alone in Postprandial Functional Dyspepsia

Dyspepsia | Functional Gastrointestinal Disorders

United Kingdom
VA Office of Research and Development

Completed

rTMS for Emotional Difficulties in Verterans (rTMS)

Depression | PTSD | Anxiety | Mental Health | Psychosocial Impairment | rTMS

United States
Ono Pharma USA Inc
Ono Pharmaceutical Co. Ltd

Completed

An Open-label, Single-dose, Intravenous Administration Study of ONO-2745/CNS 7056 in Subjects With Chronic Hepatic Impairment

Healthy | Hepatic Impairment

United States
The George Institute
Chinese University of Hong Kong; Monash University; The Alfred; University of Sydney and other collaborators

Recruiting

Statin TReatment for COVID-19 to Optimise NeuroloGical recovERy (STRONGER)

Neurocognitive Impairment, Mild

Australia
Medical University of South Carolina
National Center of Neuromodulation for Rehabilitation

Completed

Plasticity Using Stimulation and Habit: A Pilot Open-label rTMS Study for MCI (PUSH-Pilot)

Mild Cognitive Impairment

United States
The University of New South Wales

Completed

Transcranial Direct Current Stimulation to Enhance Cognition in Mild Cognitive Impairment

Mild Cognitive Impairment

Australia
Medical University of South Carolina
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institutes...

Recruiting

rTMS in Older Adults With MCI and AUD

Transcranial Magnetic Stimulation | Mild Cognitive Impairment | Alcohol Use Disorder

United States
Sheffield Teaching Hospitals NHS Foundation Trust

Recruiting

Traditional Dietary Advice Vs. Mediterranean Diet in IBS

Irritable Bowel Syndrome

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

A Study Comparing the Effectiveness and Convenience of Dietary Therapy for Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome

United Kingdom
Aghia Sophia Children's Hospital of Athens
BioGaia AB

Completed

Efficacy of Dietary Supplementation With Lactobacilllus Reuteri DSM 17938 on Functional Abdominal Pain (FAP) in Children

Functional Abdominal Pain (FAP) in Children

Greece, Poland, Slovenia
Medical University of South Carolina
National Institute on Aging (NIA)

Recruiting

Transcranial Magnetic Stimulation for MCI (PUSH2)

Depression | Mild Cognitive Impairment

United States
Nutricia Research

Unknown

Neocate In Infants and Children With Complex Conditions (NICC)

Complex Conditions, Including Impairment of the GI Tract

United Kingdom, United States, Germany
Medical University of South Carolina
National Institutes of Health (NIH)

Active, not recruiting

Learning in Stroke

Stroke | Sensorimotor Impairment

United States
Sucampo Pharma Americas, LLC
Sucampo AG

Completed

Evaluation of the Safety of Lubiprostone in Pediatric Participants Aged ≥ 6 Years to < 18 Years With Functional Constipation

Constipation - Functional

United States
University of Western Sydney

Completed

Memory Encoding Strategies for People With Mild Cognitive Impairments

Mild Cognitive Impairment | Mild Dementia

Hong Kong, Australia
Westat
United States Social Security Administration

Completed

Supported Employment Demonstration (SED)

Mental Impairment

United States
University of South Carolina
Centers for Disease Control and Prevention

Recruiting

Mindful Walking Program for Older African Americans

Cognitive Function | Behavior, Health | Aging Well

United States
Eisai Inc.
Eisai Limited

Completed

Efficacy and Safety of Donepezil Hydrochloride in Preadolescent and Adolescent Children With Attention Impairment Following Cancer Treatment

Attention Impairment

United States, Netherlands, France, Spain, United Kingdom, Germany, Argentina, Canada, Australia, Chile
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Cognitive Training for Cancer Related Cognitive Impairment in Breast Cancer Survivors

Breast Cancer | Cognitive Impairments

United States
Sheffield Children's NHS Foundation Trust

Completed

Assessment of an Augmented Reality Low Visual Aid in Children and Young People With Visual Impairment

Vision Disability

United Kingdom
Case Comprehensive Cancer Center

Terminated

Older Patients With Newly Diagnosed Breast Cancer or Colon Cancer

Breast Cancer | Colorectal Cancer | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment

United States
University of Western Sydney

Active, not recruiting

Computer-based Cognitive Rehabilitation Program for Healthy Older Adults, Older People With Mild Cognitive Impairment and Mild Dementia

Mild Cognitive Impairment | Mild Dementia | Healthy Older Adults

Australia
Anji Pharma
Covance

Completed

A Proof of Concept Study of Pradigastat in Patients With Functional Constipation

Functional Constipation

China, United States
Allergan
Ironwood Pharmaceuticals, Inc.

Completed

Linaclotide Safety and Efficacy in 2 to 5-Year-Old Participants With Functional Constipation

Functional Constipation

United States
Clemson University
University of Alabama at Birmingham; National Institute on Aging (NIA); Penn...

Recruiting

Elucidating the Necessary Active Components of Training (ENACT)

Cognitive Impairment | Cognitive Change | Alzheimer Disease

United States
Woolcock Institute of Medical Research

Recruiting

Digital Sleep Therapy for Older Adults With Cognitive Impairment (ExCEED)

Cognitive Impairment | Insomnia Type; Sleep Disorder

Australia
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; University of Liverpool

Completed

Muscle in Obesity: Imaging, Function and microRNA

Muscle Function

United Kingdom
AbbVie
Ironwood Pharmaceuticals, Inc.

Recruiting

A Study to Assess Adverse Events and Change in Disease Activity in Pediatric Participants (Age 6 Months to <2 Years) With Functional Constipation Who Are Treated With Linaclotide

Functional Constipation

United States, Bulgaria, United Kingdom, Croatia, Germany, Hungary
Medical University of South Carolina
National Center for Advancing Translational Sciences (NCATS)

Completed

SUPPORT-D Intervention for Persons With Alzheimer's Disease and Their Caregivers

Alzheimer Disease | Mild Cognitive Impairment

United States
Medical University of South Carolina
National Cancer Institute (NCI)

Recruiting

Building a Renewed ImaGe After Head & Neck Cancer Treatment (BRIGHT) Multi-Site RCT (BRIGHT)

Head and Neck Cancer | Body Image Disturbance | Body Image | Psychosocial Impairment | Survivorship | Mental Health Issue

United States
Medical University of South Carolina
National Institute of Neurological Disorders and Stroke (NINDS); National Institutes...

Completed

Functional Viability Duck Duck Punch (DDPSBIR)

Stroke | Rehabilitation | Recovery of Function

United States
GlaxoSmithKline

Completed

A Study To Investigate GW427353 In Subjects With Irritable Bowel Syndrome (IBS)

Irritable Bowel Syndrome (IBS)

Germany, Australia, France
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of PDR001 in Patients With Advanced or Metastatic, Well-differentiated, Non-functional Neuroendocrine Tumors of Pancreatic, Gastrointestinal (GI), or Thoracic Origin or Poorly-differentiated Gastroenteropancreatic Neuroendocrine Carcinoma (GEP-NEC)

Well-differentiated Non-functional NET of Thoracic Origin | Well-differentiated Non-functional NET of Gastrointestinal Origin | Well-differentiated Non-functional NET of Pancreatic Origin | Poorly-differentiated Gastroenteropancreatic Neuroendocrine Carcinoma

United States, Italy, Spain, Japan, Belgium, Netherlands, Germany, France, Canada, Austria, United Kingdom, Australia
Memory Pharmaceuticals

Unknown

Study to Evaluate the Safety and Efficacy of MEM 3454 as Adjunctive Treatment in Combination With a Preexisting Antipsychotic in Patients With Cognitive Impairment Associated With Schizophrenia

Cognitive Impairment Associated With Schizophrenia

United States

Clinical Trials on Functional Impairment in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

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CROs in Moldova

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

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