Clinical Trials on Gout and Asymptomatic Hyperuricemia in Germany

Total 78 results

Novartis

Completed

Efficacy and Safety of Lumiracoxib 400 mg Once Daily in Acute Flares of Gout

Acute Gouty Arthritis

Germany, Switzerland
Novartis Pharmaceuticals

Completed

Long-Term Safety and Tolerability of Canakinumab Prefilled Syringes in Frequently Flaring Acute Gouty Arthritis Patients

Acute Gouty Arthritis

Germany, United States, Lithuania, Canada
University Medicine Greifswald
Wuerzburg University Hospital; University of Göttingen

Recruiting

Prednisolone Versus Colchicine for Acute Gout in Primary Care (COPAGO)

Acute Gout

Germany
Novartis Pharmaceuticals

Completed

β-RELIEVED - REsponse in Acute fLare and In prEVEntion of episoDes of Re-flare in Gout - Extension 3 (E3) (β-RELIEVED)

Acute Gouty Arthritis Flares

United States, Estonia, Lithuania, Germany, Russian Federation, Canada, Australia, Latvia, Ukraine
Novartis Pharmaceuticals

Completed

Long Term Study of Canakinumab (ACZ885) in Patients With Gout

Gouty Arthritis

Colombia, Spain, Taiwan, Russian Federation, Guatemala, Belgium, United States, Argentina, Czechia, Germany, Hungary, Poland, Portugal, Singapore, Slovakia, South Africa, Turkey, United Kingdom
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Canakinumab Prefilled Syringes in Frequently Flaring Acute Gouty Arthritis Patients

Acute Gouty Arthritis

Hungary, Germany, United States, Lithuania, Canada
Celldex Therapeutics

Completed

A Single Dose Study of the Safety, Pharmacokinetics and Pharmacodynamics of CDX-0159 in Patients With Cold Contact Urticaria, Symptomatic Dermographism, or Cholinergic Urticaria

Cold Urticaria | Symptomatic Dermographism | Cholinergic Urticaria | Cold Contact Urticaria | Symptomatic Dermatographism

Germany
German Resuscitation Registry
European Resuscitation Council (ERC)

Completed

A Multi-centre Survey of Epidemiology, Treatment and Outcome of Patients Suffering an Out-of-hospital Cardiac Arrest (EuReCaONE)

Out of Hospital Cardiac Arrest

Germany
Novartis

Completed

Efficacy and Safety of Valsartan Versus Placebo on Exercise Tolerance in Patients With Heart Failure

Diastolic Dysfunction, Symptomatic Heart Failure

Switzerland, Germany
German Resuscitation Registry

Completed

European Registry of Cardiac Arrest Study Two (EuReCa TWO)

Out-Of-Hospital Cardiac Arrest | Resuscitation Registry

Germany
St.Bernward Hospital
University Medical Center Goettingen

Recruiting

Feedback Intervention and Treatment Trial in Patients With Out-of-Hospital Cardiac Arrest (FITT-OHCA)

Out-Of-Hospital Cardiac Arrest

Germany
Charite University, Berlin, Germany
Novartis Pharmaceuticals

Completed

Urticaria Facticia Treatment With Omalizumab (UFO) (UFO)

Symptomatic Dermographism

Germany
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Abbreviated Breast MRI and Digital Tomosynthesis Mammography in Screening Women With Dense Breasts

Asymptomatic

United States, Germany
Charite University, Berlin, Germany
German Federal Ministry of Education and Research

Terminated

Mesh Ablator Versus Cryoballoon Pulmonary Vein Ablation of Symptomatic Paroxysmal Atrial Fibrillation (MACPAF)

Symptomatic Paroxysmal Atrial Fibrillation

Germany
University Hospital Schleswig-Holstein
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Completed

Immediate Unselected Coronary Angiography Versus Delayed Triage in Survivors of Out-of-hospital Cardiac Arrest Without ST-segment Elevation (TOMAHAWK)

Out-of-hospital Cardiac Arrest

Germany
Biotronik AG

Completed

Self Expanding Nitinol Stent Versus Percutaneous Transluminal Arterial Angioplasty (PTA) With Optional Bailout Stenting in Case of PTA Failure in Patients With Symptomatic Critical Limb Ischemia or Severe Intermittent Claudication (EXPAND) (EXPAND)

Severe Intermittent Claudication | Patients With Symptomatic Critical Limb Ischemia

Germany
Klinik für Kardiologie, Pneumologie und Angiologie

Completed

Electrophysiologic HV-interval as a Predicor for Permanent Pacemaker Implantation After TAVI

Symptomatic Aortic Valve Stenosis

Germany
Experimental and Clinical Research Center

Enrolling by invitation

Inulin and the Gut Microbiota in Healthy Adults (INLITE)

Gut Microbiota Dysbiosis and Nutrition

Germany
Ardea Biosciences, Inc.

Completed

Gout Dose Response Study

Hyperuricemia

Poland, United States, Canada, Bulgaria, Germany, Georgia, Czech Republic
University Hospital, Essen

Recruiting

Influence of Enteral Microbiome on Mortality of Patients With Cardiogenic Shock

Microbial Colonization | Acute Myocardial Infarction | Cardiogenic Shock | Out-Of-Hospital Cardiac Arrest | Acute Heart Failure

Germany
Sanofi

Terminated

Rasburicase for the Treatment/Prevention of Hyperuricemia in Adult Patients With Relapsing Aggressive Non Hodgkin's Lymphoma (GRAAL2)

Hyperuricemia

Germany, Belgium, Italy, France
Goethe University

Completed

Treatment of Hyperuricemia With Rasburicase in Patients With Acute Lymphoblastic Leukemia or High Grade Lymphoma

Adult Acute Lymphocytic Leukemia | High-grade Lymphoma

Germany
Karolinska Institutet

Recruiting

Prehospital Resuscitation Intranasal Cooling Effectiveness Survival Study 2 (PRINCESS2)

Ventricular Fibrillation | Hypothermia | Out-Of-Hospital Cardiac Arrest

Sweden, Spain, Germany, Belgium, Austria, Italy, Slovenia
University of Aarhus

Completed

Time-differentiated Therapeutic Hypothermia (TTH48)

Out of Hospital Cardiac Arrest

Belgium, Denmark, Estonia, Finland, Germany, Norway
Heinrich-Heine University, Duesseldorf

Recruiting

The VANGAS-Trial. The Value of Neurofilament Light Chain and Glial Fibrillary Acid Protein in the Blood of Patients With Asymptomatic Carotid Artery Stenosis (VANGAS)

Carotid Artery Plaque | Carotid Artery Diseases | Carotid Artery Stenosis Asymptomatic | Carotid Artery Stenosis

Germany
University of Erlangen-Nürnberg Medical School
German Sport University, Cologne

Completed

Effects of Compression Wear on Muscle Soreness (COMDOME)

Muscular Regeneration | Repeated Bout Effect of WB-EMS

Germany
Novartis Pharmaceuticals

Completed

Canakinumab in the Treatment of Acute Gout Flares and Prevention of New Flares in Patients Unable to Use Non-steroidal Anti-inflammatory Drugs (NSAIDs) and/or Colchicine Including a 12 Weeks Extension and an Open-label 48 Weeks Extension Study (β-RELIEVED)

Acute Gout

Colombia, Switzerland, Germany, Russian Federation, Singapore, Australia, Belgium, Canada, Estonia, Guatemala, Latvia, Lithuania, Mexico, Norway, Poland, Sweden, Ukraine
Conor Medsystems

Terminated

CoStar Catheter System Evaluation (CONCISE)

Symptomatic Ischemic Heart Disease

Germany
Novartis

Completed

Targeted Dose Finding of Canakinumab (ACZ885) for Management of Acute Flare in Refractory or Contraindicated Gout Patients

Acute Gout

United States, Russian Federation, Switzerland, Germany, Turkey, Poland, Argentina, Canada, Belgium, France, United Kingdom
Symetis SA

Completed

ACURATE™ Transapical Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis (2010-01) (TA-PILOT)

Aortic Symptomatic Stenosis

Germany
Symetis SA

Completed

Feasibility Trial on ACURATE™ Transapical Implantation in Patients With Severe Symptomatic Aortic Stenosis (2009-01) (TA-FIM)

Aortic Stenosis Symptomatic

Germany
ZOLL Circulation, Inc., USA
Instituto de Investigación Hospital Universitario La Paz

Completed

Finding the Optimal Cooling tempeRature After Out-of-HoSpiTal Cardiac Arrest (FROST)

Out-Of-Hospital Cardiac Arrest

Germany, Spain
Mitralign, Inc.
CardioVascular Research Foundation, Korea; Regulatory and Clinical Research... and other collaborators

Unknown

Safety and Performance of the Trialign Percutaneous Tricuspid Valve Annuloplasty System (PTVAS) (SCOUT-II)

Heart Valve Disease | Tricuspid Valve Insufficiency | Chronic Symptomatic Functional Tricuspid Regurgitation

Italy, Netherlands, Germany, Portugal
Leipzig Heart Science gGmbH
Charite University, Berlin, Germany; Klinikum Ludwigshafen; St. Antonius Hospital and other collaborators

Recruiting

German Cardiac Arrest Registry (G-CAR)

Out-of-hospital Cardiac Arrest

Germany
Symetis SA

Completed

ACURATE TF™ Transfemoral Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis (2011-03) (2011-03)

Aortic Stenosis Symptomatic

Germany, Brazil
Symetis SA

Completed

ACURATE TF™ Transfemoral Aortic Bioprosthesis for Implantation in Patients With Severe Aortic Stenosis:CE-approval Cohort

Symptomatic Aortic Stenosis

Germany, Japan, Brazil
Medtronic Atrial Fibrillation Solutions
Medtronic

Completed

FIRE AND ICE: Comparative Study of Two Ablation Procedures in Patients With Atrial Fibrillation

Symptomatic Paroxysmal Atrial Fibrillation (PAF)

Germany, Czechia, France, Hungary, Italy, Netherlands, Spain, Switzerland
Universität Duisburg-Essen

Completed

Effects of Fasting on Self Efficacy (TheraFast)

Gastrointestinal Diseases | Cardiovascular Diseases | Arthritis | Rheumatoid Arthritis | Chronic Pain | Irritable Bowel Syndrome | Fibromyalgia | Headache | Inflammatory Bowel Disease | Gout

Germany
Biosense Webster, Inc.

Completed

THERMOCOOL® SMARTTOUCH™ Registry

Symptomatic Atrial Fibrillation

Belgium, Germany, United Kingdom, Canada, Australia, France, Italy, Monaco
Symetis SA

Completed

ACURATE TA™ Valve Implantation: SAVI Registry (Surveillance Plan #2011-02) (TA-SAVI)

Symptomatic Aortic Stenosis

Germany, Italy, Argentina, Switzerland
Novartis Pharmaceuticals

Recruiting

Study of Efficacy, Safety and Tolerability of DFV890 in Patients With Knee Osteoarthritis

Symptomatic Knee Osteoarthritis

United States, Spain, Hungary, Argentina, Germany, Slovakia, Czechia, Belgium, Romania
Menarini International Operations Luxembourg SA

Completed

Intensive Urate Lowering Therapy of Febuxostat Compared to Allopurinol on Cardiovascular Risk in Patients With Gout (FORWARD)

Gout

Poland, Serbia, Germany, Italy, Netherlands, Romania
University Hospital, Saarland
Universität des Saarlandes

Active, not recruiting

Characterization of the Microbiome in Peritoneum, Jejunum, Rectum and Stool (METABIOM)

Obesity | Diabetes Mellitus | Chronic Pancreatitis | Fatty Liver, Nonalcoholic | Leaky Gut Syndrome

Germany
Bayer

Recruiting

A Study to Learn More About How Well BAY3018250 Works and How Safe it is for People With Proximal Deep Vein Thrombosis (SIRIUS)

Thrombolysis | Symptomatic Proximal Deep Vein Thrombosis

Belgium, France, Italy, Netherlands, Canada, Germany, Czechia
Abbott Medical Devices

Completed

Portico TAVI Implant With Transfemoral Delivery System

Symptomatic Aortic Stenosis

United Kingdom, Germany, Netherlands, Denmark, Australia
Medtronic Cardiac Rhythm and Heart Failure
Medtronic Atrial Fibrillation Solutions

Completed

Catheter Cryoablation Versus Antiarrhythmic Drug as First-Line Therapy of Paroxysmal Atrial Fibrillation

Symptomatic Paroxysmal Atrial Fibrillation Without Clinically Significant Heart Diseases

Netherlands, Australia, France, Norway, Germany, Croatia, Italy, Argentina, Belgium
Claret Medical

Completed

Cerebral Protection in Transcatheter Aortic Valve Replacement

Severe Symptomatic Calcified Native Aortic Valve Stenosis

United States, Germany
Assistance Publique - Hôpitaux de Paris
Action Research Group; Bristol-Meyers Squibb & Pfizer

Completed

Anti-Thrombotic Strategy After Trans-Aortic Valve Implantation for Aortic Stenosis (ATLANTIS)

Symptomatic Aortic Stenosis | Eligible for Transcatheter Aortic Valve Replacement

France, Germany, Italy, Spain
Keystone Heart

Completed

The REFLECT Trial: Cerebral Protection to Reduce Cerebral Embolic Lesions After Transcatheter Aortic Valve Implantation

Symptomatic Aortic Stenosis

United States, Netherlands, Germany, Italy
Abbott Medical Devices

Recruiting

Evaluation of TAVR Using the NAVITOR Valve in a Global Investigation (VANTAGE)

Symptomatic Severe Aortic Stenosis

Spain, Denmark, United Kingdom, France, Italy, Australia, Germany, Netherlands, Switzerland, Austria

Clinical Trials on Gout and Asymptomatic Hyperuricemia in Germany

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