Effects of Compression Wear on Muscle Soreness (COMDOME)

Effects of Compression Wear on Whole-body Electromyostimulation and Exercise-induced Muscle Soreness. A Randomized Controlled Trial.

The study address two main topics:

1. The effect of compression garment on whole-body electromyostimulation (WB-EMS) induced muscle soreness in young adults
2. The repeated bout effect of one intense session of WB-EMS as determined by various regeneration parameters

Study Overview

• Status: Completed
• Conditions: Muscular Regeneration; Repeated Bout Effect of WB-EMS
• Intervention / Treatment: Other: Compression

Detailed Description

Using a cross-over design we applied 2 intense WB-EMS training sessions either with or without subsequent wearing of compression garments (long tights) for 5 days at baseline and after a washout period of 4 weeks. Healthy young to middle aged athletes used compression garments immediately postexercise for 24 hours and further 12 h during the day. Blood samples, questionnaires, resting metabolic rate and performance test were applied prior and 24, 48,72 and 96 h post-exercise consistently without wearing compression garments.

• Study Type: Interventional
• Enrollment (Actual): 23
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Germany
  • Erlangen, Germany, 91052
    • Institute of Medical Physics University of Erlangen-Nurnberg
  • Erlangen, Germany, 91052
    • Institute of Medical Physics, University of Erlangen-Nurnberg

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 25 years to 50 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: Male

Description

Inclusion Criteria:

• healthy athletes with >5 years of experience in competition balls sports and corresponding discipline specific resistance exercise

Exclusion Criteria:

• diseases and medication affecting muscle metabolism
• contraindication for WB-EMS

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Crossover Assignment
• Masking: Double

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Compressive garment; Groups wear compression garment after WB-EMS induced muscle soreness	Other: Compression; Participants in the treatment group wear compression garment after intense WB-EMS application for 24 h, and 12 h for day 2, 3, 4 post WB-EMS.
No Intervention: No compression garment; Groups wear no compression garment after WB-EMS induced muscle soreness

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Maximum isokinetic leg extensor strength	Changes of isokinetic leg extensor strength during the intervention period	5 days

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Perceived physical state	Changes of perceived physical state as determined by the WKV-scale (Kleinert, 2001) during the intervention period	5 days
Resting metabolic rate	Changes of resting metabolic rate during the intervention period	5 days
Myoglobin	Changes of myoglobin-levels during the intervention period	5 days
Heart rate variability	Changes of Heart rate variability during the intervention period	5 days
creatine-kinase (CK) concentration	Changes of CK-levels during the intervention period	5 days

Collaborators and Investigators

• Sponsor: University of Erlangen-Nürnberg Medical School
• Collaborators: German Sport University, Cologne
• Investigators: Study Chair: Helmut Lötzerich, PhD, German Sport University, Cologne; Principal Investigator: Wolfgang Kemmler, PhD, University of Erlangen-Nürnberg Medical School

Publications and helpful links

General Publications

• Kemmler W, Teschler M, Bebenek M, von Stengel S. [(Very) high Creatinkinase concentration after exertional whole-body electromyostimulation application: health risks and longitudinal adaptations]. Wien Med Wochenschr. 2015 Nov;165(21-22):427-35. doi: 10.1007/s10354-015-0394-1. Epub 2015 Oct 26. German.

Helpful Links

• Institution homepage

Study record dates

Study Major Dates

• Study Start (Actual): December 10, 2017
• Primary Completion (Actual): February 22, 2018
• Study Completion (Actual): May 31, 2018

Study Registration Dates

• First Submitted: January 24, 2018
• First Submitted That Met QC Criteria: January 24, 2018
• First Posted (Actual): January 31, 2018

Study Record Updates

• Last Update Posted (Actual): July 6, 2018
• Last Update Submitted That Met QC Criteria: July 4, 2018
• Last Verified: July 1, 2018

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Nervous System Diseases; Pain; Neurologic Manifestations; Musculoskeletal Diseases; Muscular Diseases; Neuromuscular Diseases; Musculoskeletal Pain; Myalgia
• Other Study ID Numbers: Compression_DOMS_EMS

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: Undecided

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No