Clinical Trials on Hypertension, Essential in Ireland

Total 254 results

Novartis

Completed

Efficacy and Safety of Aliskiren 75 mg, 150 mg, and 300 mg in Elderly Patients With Essential Hypertension When Given With a Light Meal in a 8 Week Placebo-controlled Study

Hypertension

Slovakia, Italy, Netherlands, Argentina, Germany, Poland, Czech Republic, Iceland
RostaQuo S.p.A.

Unknown

Antihypertensive Effect of Rostafuroxin Compared With Losartan in Hypertensive Patients Bearing Specified Gene Mutations

Essential Hypertension

Ireland, Italy, Poland
Takeda

Completed

Efficacy and Safety of Azilsartan Medoxomil Co-Administered With Chlorthalidone in Participants With Essential Hypertension

Hypertension

United States
Takeda

Completed

Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone Compared to Olmesartan Medoxomil and Hydrochlorothiazide in Participants With Moderate to Severe Hypertension.

Essential Hypertension

United States, Canada
Eli Lilly and Company

Completed

A Study of LY2623091 in Participants With High Blood Pressure

Primary Hypertension

United States, Puerto Rico, Canada
Takeda

Completed

Efficacy and Safety of Azilsartan Medoxomil and Chlorthalidone in Participants With Moderate to Severe Hypertension

Essential Hypertension

United States, Russian Federation
Symplmed Pharmaceuticals LLC

Completed

Perindopril Amlodipine for the Treatment of Hypertension (PATH)

Essential Hypertension

United States
Takeda

Completed

Efficacy and Safety of Azilsartan Medoxomil, Once Daily (QD), Co-Administered With Amlodipine in Participants With Essential Hypertension

Hypertension

United States
University of Ulster
DSM Ltd; Public Health Agency (Northern Ireland)

Recruiting

Optimal Nutrition for Prevention of Hypertension in Pregnancy (OptiPREG)

Pregnancy | Blood Pressure

Ireland, United Kingdom
Idorsia Pharmaceuticals Ltd.

Completed

Dose-finding Study With ACT-132577 (Aprocitentan) in Participants With Essential Hypertension

Essential Hypertension

United States, Canada, Israel, Puerto Rico
Takeda

Completed

Efficacy and Safety of Azilsartan Medoxomil Plus Chlorthalidone in Participants With Moderate to Severe Hypertension

Essential Hypertension

United States, Chile, Mexico
GlaxoSmithKline

Completed

Research Study To Test Carvedilol CR + Lisinopril Versus Lisinopril + Placebo In Patients With High Blood Pressure

Hypertension

United States
Theracos

Completed

An Integrated Assessment of the Safety and Effectiveness of Bexagliflozin for the Management of Essential Hypertension

Essential Hypertension

United States
Takeda

Completed

Efficacy and Safety Comparison of Azilsartan Medoxomil to Valsartan in Participants With Essential Hypertension

Hypertension

United States, Mexico, Chile, Peru
Pfizer

Completed

Ramipril and Hydrochlorothiazide Alone and in Combination for the Treatment of Essential Hypertension

Hypertension | Blood Pressure, High

United States
NicOx

Completed

To Assess the Effect of Naproxcinod Versus Naproxen and Ibuprofen on Arterial Blood Pressure in Osteoarthritis Patients With Controlled Essential Hypertension (HCT3012-X-112)

Hypertension | Osteoarthritis

United States
University College Cork
Science Foundation Ireland

Unknown

Learning to Evaluate Blood Pressure at Home (LEANBH) (LEANBH)

Hypertension in Pregnancy

Ireland
Queen's University, Belfast
Mayo Clinic; University Hospital Southampton NHS Foundation Trust; University... and other collaborators

Completed

Myeloproliferative Neoplasms: an In-depth Case-control Study (MOSAICC)

Primary Myelofibrosis | Polycythemia Vera | Essential Thrombocythemia

United Kingdom
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Evaluate The Clinical Effectiveness, Safety And Tolerability Of Sildenafil Used In Doses ≥20mg TID For The Treatment Of Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

Germany, Ireland
University College Cork

Completed

Human Intervention Study of Egg Protein Derivative on Cardiovascular Risk (CardiProtein)

Hypertension

Ireland
University College Cork

Completed

Effects of Blackberry-derived Polyphenols on Cardiovascular Risk in Adults (Cardio-Rubus)

Hypertension

Ireland
Novartis Pharmaceuticals

Completed

Panobinostat and Ruxolitinib in Primary Myelofibrosis, Post-polycythemia Vera-myelofibrosis or Post-essential Thrombocythemia-myelofibrosis

Idiopathic Myelofibrosis | Post Essential Thrombocythemia Myelofibrosis | Post Polycythemia-Vera Myelofibrosis

United Kingdom, Ireland, Germany, Italy, France
University College Cork

Completed

'Low-salt' Bread as a Means of Reducing Dietary Salt and Lowering Blood Pressure (Saltbreads)

Elevated Blood Pressure

Ireland
Queen's University, Belfast
University of Sussex

Unknown

Determining the Clinical Utility of Using Virtual Reality Headsets to Assess Visual Function in Those With Glaucoma.

Glaucoma

United Kingdom
Queen's University, Belfast

Completed

Glaucoma Within Northern Ireland Cohort for the Longitudinal Study of Ageing (GwNICOLA)

Glaucoma

United Kingdom
Copenhagen University Hospital at Herlev

Unknown

A Study of the Efficacy of MK-0683 in Patients With Polycythaemia Vera and Essential Thrombocythaemia

Polycythemia Vera | Essential Thrombocythemia

Sweden, United Kingdom, Denmark, Netherlands
Centre for Eye Research Ireland

Completed

European Nutrition in Glaucoma Management Trial (ENIGMA)

Glaucoma, Open-Angle

Ireland
Lung Biotechnology PBC

Completed

A Multi-Center, Open-Label, Multiple Dose, Dose Finding Study Exploring the Safety and Tolerability of Beraprost Sodium Modified Release in PAH Patients

Pulmonary Arterial Hypertension

United States, Ireland, Belgium
National University of Ireland, Galway, Ireland

Suspended

The Galway Sea Swimmers Study (GS3)

Cardiovascular Diseases | Hypertension

Ireland
Lung Biotechnology PBC

Completed

An Open-Label Extension of BPS-MR-PAH-201 in Pulmonary Arterial Hypertension (PAH) Patients

Pulmonary Arterial Hypertension

United States, Belgium, Ireland
University College Hospital Galway
National University of Ireland, Galway, Ireland; European Research Council

Completed

Clarifying Optimal Sodium Intake Project (COSIP-1)

Hypertension | Cardiovascular Disease | Blood Pressure | Kidney Disease

Ireland
University College Cork
Osypka Medical, Berlin, Germany

Terminated

Non-invasive Objective Assessment of Hemodynamics in Preterm Neonates (NOAH)

Intraventricular Hemorrhage | Hemodynamic Instability | Hypotension and Shock | Hypoperfusion | Cardiac Function | Circulatory Transition

Ireland
Ronald Hoffman
National Cancer Institute (NCI); Roche Pharma AG; Myeloproliferative Disorders-Research...

Completed

Randomized Trial of Pegylated Interferon Alfa-2a Versus Hydroxyurea in Polycythemia Vera (PV) and Essential Thrombocythemia (ET)

High Risk Polycythemia Vera | High Risk Essential Thrombocythemia

United States, Italy, United Kingdom, France
Praxis Precision Medicines

Withdrawn

A Clinical Trial of PRAX-114 in Participants With Essential Tremor

Essential Tremor

United States
Rhode Island Hospital

Active, not recruiting

Effects of DHEA in Pulmonary Hypertension (EDIPHY)

Pulmonary Arterial Hypertension

United States
Cala Health, Inc.

Completed

A Pilot Study of the Cala ONE Device for Essential Tremor (EXCITE)

Essential Tremor

United States
Eko Devices, Inc.

Recruiting

Development of an Algorithm to Detect Pulmonary Hypertension Using an Electronic Stethoscope

Pulmonary Hypertension

United States
University of Pennsylvania

Completed

Anastrozole in Patients With Pulmonary Arterial Hypertension (AIPH)

Pulmonary Arterial Hypertension

United States
Women and Infants Hospital of Rhode Island

Completed

App-based Remote Blood Pressure Monitoring

Preeclampsia | Gestational Hypertension | Chronic Hypertension Complicating Pregnancy

United States
Renal Dynamics GmbH
Biosensors Europe SA; Physio-Logic Ltd. Israel; AmeRuss Clinical Trials LLC, USA

Unknown

A Study to Evaluate Safety and Efficacy of the Redy™ Renal Denervation System in the Treatment of Patients With Uncontrolled Hypertension

Hypertension Resistant to Conventional Therapy

Israel, Belgium, Germany, Hungary, Ireland, Poland, Russian Federation, Serbia
Lifespan

Recruiting

Mindfulness & Mechanisms Study

Hypertension in Pregnancy

United States
Lifespan
National Institute of General Medical Sciences (NIGMS)

Completed

Prenatal Mindfulness & Hypertension Study (HTN)

Hypertension in Pregnancy

United States
E-Star BioTech, LLC
Mayo Clinic; Integrium

Completed

Safety And Tolerability Of Subcutaneous MANP In Difficult To Control/Resistant Hypertensive Subjects (DTC/RHS)

Resistant Hypertension | Difficult to Control Hypertension

United States
University College Hospital Galway
Health Research Board, Ireland

Completed

Sleep to Lower Elevated Blood Pressure (SLEPT)

Cardiovascular Diseases | Hypertension | Insomnia | Sleep Disorders

Ireland
National University of Ireland, Galway, Ireland

Suspended

Coronavirus (COVID-19) ACEi/ARB Investigation (CORONACION)

COVID-19 | Hypertension

Ireland
St Vincent's University Hospital, Ireland
University College Dublin; The Heartbeat Trust; Crofton Cardiac Centre, Dublin

Completed

St. Vincent's Screening To Prevent Heart Failure Study (STOP-HF)

Myocardial Infarction | Hypertension | Obesity | Diabetes | Left Ventricular Dysfunction

Ireland
Mount Sinai Hospital, Canada
Sunnybrook Health Sciences Centre; University of Iowa; The Rotunda Hospital; BC... and other collaborators

Active, not recruiting

Novel Echocardiographic Methods for Early Identification of Neonates at Risk for Chronic Pulmonary Hypertension

Pulmonary Hypertension | Infant, Premature

Canada, United States, Ireland, United Kingdom
Wen-Chih Wu

Withdrawn

Reversal of Right Ventricular Steatosis in Pulmonary Hypertension

Steatosis | Right Ventricular Failure | Pulmonary; Hypertension

United States
University College Dublin
Royal College of Surgeons, Ireland; National Maternity Hospital, Ireland; Perinatal...

Completed

Trial of Early Screening Test for Pre-eclampsia and Growth Restriction (TEST)

Placenta Diseases | Pre-Eclampsia | Fetal Growth Retardation | Eclampsia Preeclampsia | Foetal Growth Restriction

Ireland
Irish Centre for Fetal and Neonatal Translational...
University College Cork; National Maternity Hospital, Ireland; Coombe Women and... and other collaborators

Completed

Placental Growth Factor Assessment of Women With Suspected Pre-eclampsia (PARROT)

Pregnancy Complications | Pregnancy, High Risk | Pre-eclampsia

Ireland

Clinical Trials on Hypertension, Essential in Ireland

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