Clinical Trials on Immune System Processes

Total 230077 results

Kadmon, a Sanofi Company

Completed

A Study to Assess the Effect of Oral Belumosudil on Inhibition of Various Proteins in the Fed State in Healthy Male Subjects

Immune System Disorder (Healthy Volunteers)

United States
Kadmon, a Sanofi Company

Completed

A Study to Determine the Effect of 500 mg Oral Dose of KD025 in Healthy Male and Post-menopausal Female Subjects

Immune System Disorder (Healthy Volunteer)

United States
Kadmon, a Sanofi Company

Completed

A Study to Determine the Effect of Multiple Oral Doses and Regimens of KD025 in Healthy Male and Post-menopausal Female Subjects

Immune System Disorder (Healthy Volunteer)

United States
Kadmon, a Sanofi Company

Completed

A Study to Determine the Effect of Multiple Oral Doses of SLx-2119 in Healthy Male Subjects

Immune System Disorder (Healthy Volunteer)

United States
Cabaletta Bio

Not yet recruiting

RESET-SSc: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201, a CD19-CAR T Cell Therapy, in Subjects With Systemic Sclerosis

Systemic Sclerosis | Scleroderma

United States
University Hospital, Bordeaux

Recruiting

Cohort of Patients With Systemic Sclerosis Within the Framework of the RESO Reference Centre (SCLERESO)

Systemic Sclerosis | Scleroderma

France
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Anakinra as a Rescue Treatment for Allergic Inflammation

Asthma, Allergic
Emory University

Completed

Rifaximin for Infection Prophylaxis in Hematopoietic Stem Cell Transplantation

Microbial Colonization

United States
Stanford University

Completed

Understanding and Diagnosing Allergic Disease in Twins

Allergies

United States
University of Wisconsin, Madison
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

AsthMatic Inflammation and Neurocircuitry Activation (MINA) (MINA)

Allergic Asthma

United States
Fundación FLS de Lucha Contra el Sida, las Enfermedades...

Completed

Study of the Effect of Atorvastatin for Reducing Aging-related Complication in HIV-infected Patients Older Than 45 Years Receiving a Protease Inhibitor-based Regimen Versus a Raltegravir-based Regimen

Aging-related Inflammation in HIV-infected Patients

Spain
University of Toronto
UVRI-IAVI HIV Vaccine Program; Entebbe General Hospital

Unknown

Effect of Antibiotics on Penile Microbiome and HIV Susceptibility Study in Ugandan Men

Foreskin HIV Susceptibility

Uganda
Marywood University

Completed

Airborne Ultrafine and Fine Particulate Matter: A Cause for Endothelial Dysfunction in Man?

Airway Inflammation

United States
Andalusian Initiative for Advanced Therapies -...
Iniciativa Andaluza en Terapias Avanzadas

Completed

Treatment With MSC in HIV-infected Patients With Controlled Viremia and Immunological Discordant Response

Discordant Immunological Response in HIV Infected Subjects

Spain
Peking Union Medical College Hospital
Xiangya Hospital of Central South University; Shengjing Hospital; Beijing Hospital and other collaborators

Completed

Prediction of Relapse Risk in Stable Systemic Lupus Erythematosus (PRESS)

Systemic Lupus Erythematosus

China
Revimmune
Washington University School of Medicine; Vanderbilt University School of Medicine

Completed

A Study of IL-7 to Restore Absolute Lymphocyte Counts in Sepsis Patients (IRIS-7-B)

Severe Sepsis With Septic Shock

United States
Centre Hospitalier Universitaire Dijon

Completed

Auto-immune Diseases and Quality of Life (QUALIMAIRAU)

Quality of Life | Systemic Auto-immune Diseases

France
Imagine Institute
Assistance Publique - Hôpitaux de Paris

Completed

Evaluation of the Efficacy of the Sequencing Method by Gene-panel (Génétique-DIH)

Primary Immuno-Deficiencies

France
Nantes University Hospital
Centre de Recherche en Nutrition Humaine Ouest (CRNH)

Recruiting

Study to Evaluate the Efficacy of a Polyamine-deficient Diet for Treating Postoperative Pain After Abdominal Surgery (POLYAMAL)

Digestive System Surgical Procedures

France
Seoul National University Hospital

Unknown

Pain Sensitivity Questionnaire and Postoperative Opioid Requirement

Postoperative Pain
Novartis Pharmaceuticals

Terminated

Effect of Fingolimod on Neurodegeneration

Cognition | Brain Volume Loss

Turkey
University Hospital Southampton NHS Foundation...
Royal Marsden NHS Foundation Trust; University College London Hospitals; Cambridge... and other collaborators

Unknown

Coronavirus Infection in Primary or Secondary Immunosuppressed Children and Adults. (ImmunoCOVID)

COVID | Infection | Immune Deficiency | Immune Suppression | Children, Adult

United Kingdom
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Comparing PI-Based to a nNRTI-based ART for Clearance of Plasmodium Falciparum Parasitemia in HIV-Infected

HIV-1 Infection | Pf Subclinical Parasitemia

Kenya, Malawi, Uganda
University of Pittsburgh
University of Zimbabwe

Completed

HIV-Target Cell Response in Women Initiating Various Contraceptive Methods in High HIV-Incidence Areas: Zim CHIC (Zim CHIC)

HIV | Contraception | Microbiota | Immune Cells (Mucosal and Systemic)

Zimbabwe
Groupe Hospitalier Pitie-Salpetriere

Completed

Monitoring the Antiphospholipid Syndrome:TOXicity of Drugs (APSTOX) (APSTOX)

Antiphospholipid Syndrome | Adverse Drug Event | Drug Toxicity | Immune Disease

France
Iuliu Hatieganu University of Medicine and Pharmacy

Completed

Interventions Meant to Improve the Outcome of Critical Care Patients in the ED

Sepsis Syndrome | Emergency Department | Biomarker

Romania
University Hospital, Montpellier

Recruiting

Epidemiology and Management of Pediatric Anaphylaxis and Allergy in the Pediatric Emergency Department of Montpellier (Ana-Ped)

Allergy | Anaphylaxis

France
National Institute of Environmental Health Sciences...

Completed

The COX-2 Gene and the Immune System

Asthma | Allergic Inflammation

United States
Marcus Altfeld, M.D., Ph.D.
GlaxoSmithKline

Completed

Study of the HIV gp120/NefTat/AS02A Vaccine to Treat Individuals With Chronic HIV-1 Infection on Highly Active Antiretroviral Therapy (HAART)

HIV Infections

United States
University of North Carolina, Chapel Hill
National Institute of Environmental Health Sciences (NIEHS)

Completed

A Study of Gamma Tocopherol-enriched Supplement on Lower Airway Responses to Inhaled Wood Smoke in Healthy Adults (SmokeyT)

Asthma | Airway Inflammation

United States
University of Michigan

Completed

Desensitization to Reduce Oral Hypersensitivity and Improve Intake for Children With Feeding Disorders

Feeding Disorder

United States
National Institute of Environmental Health Sciences...

Completed

Disease Progression and Activity in Patients With Systemic Lupus Erythematosus

Lupus

United States
Assistance Publique - Hôpitaux de Paris
ANRS, Emerging Infectious Diseases

Completed

Targeted Nurse-driven HIV Screening in Emergency Departments (DICI-VIH)

Targeted HIV Screening, Emergency Departments

France
The Wistar Institute
National Institute of Allergy and Infectious Diseases (NIAID); Hoffmann-La... and other collaborators

Completed

Antiviral Activity of Peg-IFN-Alpha-2A in Chronic HIV-1 Infection

HIV Infections

United States
Richard Burt, MD

Withdrawn

Hematopoietic Stem Cell Transplantation in Patients With Antiphospholipid Syndrome

ANTIPHOSPHOLIPID SYNDROME

United States
University Hospital, Rouen
Hoffmann-La Roche

Terminated

Prospective Evaluation Among Patients Infected by HIV 1 in Virological Failure Owing to Lack of Compliance, of the Benefit in Terms of Compliance of an Optimised Antiretroviral Treatment With Enfuvirtide (Fuzeon) Associated With Two Active Molecules (AMPHORE)

HIV Infections | HIV1 Infection

France
Fraunhofer-Institute of Toxicology and Experimental...
German Research Foundation

Completed

Study to Explore the Effects of Two Hour Inhalation of Ultrafine Carbon Black Particles on Airway Inflammation in Asthmatics

Asthma

Germany
University of Colorado, Denver

Completed

Treatment of Tracheostomy Granulomas

Granuloma | Tracheostomy

United States
Fundacion SEIMC-GESIDA
Merck Sharp & Dohme LLC

Completed

A Clinical Trial to Evaluate the Efficacy and Safety of Elvitegravir / Cobicistat / Emtricitabine / Tenofovir Alafenamide as a First-line Treatment in Naïve Patients With HIV-1 Infection With Severe Immunosuppression (GENIS)

HIV Infections | Severe Immunosuppression

Spain
University of Erlangen-Nürnberg Medical School

Completed

Comparing the Efficacy of Periarticular Bone Structure in Patients Treated With Either Tocilizumab or Tumor Necrosis Factor Blockers (Re-Bone)

Rheumatoid Arthritis

Germany
Instituto Nacional de Enfermedades Respiratorias

Unknown

Effect of Zinc and Selenium Supplementation on HIV+ Individuals on Antiretroviral Treatment.

Inflammation | HIV | Zinc Deficiency | ART | Metabolic Complication | Selenium Deficiency

Mexico
University of Colorado, Denver
Gilead Sciences; National Institute on Aging (NIA)

Completed

Exercise for Healthy Aging: The Impact of HIV and Aging on Physical Function and the Somatopause

Inflammation | Obesity | HIV | Aging, Biological

United States
National Heart, Lung, and Blood Institute (NHLBI)
Johns Hopkins University; University of Colorado, Denver; New York University; Johns... and other collaborators

Completed

Longitudinal Studies of HIV-Associated Lung Infections and Complications (Lung HIV) (LHIV)

HIV Infections | Pulmonary Complications

United States
National Institute of Environmental Health Sciences...

Completed

Children's Exposures/Health Effects/Diesel Exhaust

Asthma | Airway Inflammation

United States
University of Rochester

Terminated

Draining PLN and Synovial Inflammation in RA Knee Joints Pre and Post Anti-TNF or B Cell Depletion Therapy

Rheumatoid Arthritis

United States
CytoAgents, Inc.
TFS HealthScience

Recruiting

Study of CTO1681 for the Prevention and Treatment of CRS in DLBCL Patients Receiving CAR T-Cell Therapy

Cytokine Release Syndrome

United States
Liverpool School of Tropical Medicine
University of Copenhagen; University of Liverpool; Infectious Diseases Institute... and other collaborators

Recruiting

Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in Africa (REVISTA-DOSE)

Sepsis | Septic Shock | HIV

Uganda
Hospices Civils de Lyon

Not yet recruiting

Azathioprine in MOGAD (MOGwAI)

Central Nervous System Inflammation | MOG-IgG Associated Disease

France
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Genetic Test in Detecting Minimal Residual Disease in Samples From Younger Patients Registered on the COG-AALL08B1 Trial

Leukemia
Lund University Hospital

Recruiting

Diffusion-weighted MRI to Predict Treatment Response in Stereotactic Radiotherapy of Central Nervous System (CNS) Metastases

Brain Metastases | Radiotherapy | Sensitivity | Radionecrosis

Sweden

Clinical Trials on Immune System Processes

Sponsors and Collaborators

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Drug Interventions

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CROs in Trinidad & Tobago

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Rare Diseases

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