Clinical Trials on Impaired Cognitive Function

Total 9818 results

VA Office of Research and Development

Active, not recruiting

Implementing a Skills-Based Caregiver Training Program (Caregivers FIRST): Function QUERI 2.0

Cognitive Function | Functional Status

United States
University of California, Los Angeles

Completed

The Impact of Family Financial Support on Cognition

Impaired Cognition

United States
Novartis Pharmaceuticals

Completed

Evaluation of Hepatic Function Impairment on the Pharmacokinetics of LEE011

Normal Hepatic Function | Impaired Hepatic Function

United States
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDE225..

Normal Hepatic Function | Impaired Hepatic Function

Belgium, Germany, Israel, Bulgaria, United States
Genta Incorporated

Completed

Pharmacokinetic Study of Genasense in Subjects With Normal Renal Function, Mildly Impaired Renal Function, and Moderately Impaired Renal Function

Normal Renal Function | Mildly Impaired Renal Function | Moderately Impaired Renal Function

United States
George Mason University

Completed

Examining the Effects of (MiM) Treatment on Emotional and Cognitive Functioning of Residents in Long-term Care (MiM)

Impaired Cognition | Emotion

United States
University of Sao Paulo
Harvard Medical School (HMS and HSDM); University of Copenhagen; Fundação de... and other collaborators

Completed

Digital Game: A Scale to Evaluate the Perioperative Cognitive Function (MentalPlus®)

Cognition Disorders | Impaired Cognition | Self-Assessment

Brazil
Taiho Oncology, Inc.

Completed

Evaluating Patients With Impaired Hepatic Function

Impaired Hepatic Function

United States
National Yang Ming University

Unknown

Interactive Stepping Exercise on Memory

Cognitive Function | Executive Function | Amnestic Mild Cognitive Impairment | Memory | Interactive Stepping Exercise
NGM Biopharmaceuticals, Inc

Completed

Study of Aldafermin (NGM282) in Participants With Impaired Hepatic Function

Impaired Hepatic Function

United States
Tetraphase Pharmaceuticals, Inc.

Completed

A Phase 1, Open-Label Study to Assess the Single-Dose Pharmacokinetics of Eravacycline in Subjects With Impaired Hepatic Function and Healthy Subjects

Impaired Hepatic Function

United States
Repros Therapeutics Inc.

Completed

Evaluate the Safety and PK of Proellex® in Female Patients With Impaired Hepatic Function and Healthy Adults

Impaired Liver Function

United States
Alexion

Recruiting

Study of ALXN2050 in Participants With Hepatic Impairment

Healthy | Impaired Hepatic Function

United States
Zhejiang University

Recruiting

MIND Diet and Cognitive Function in Adults With MCI

Mild Cognitive Impairment | Cognitive Function | Cognitive Decline

China
Danish Dementia Research Centre

Completed

Brief Assessment of Impaired Cognition (BASIC)

Dementia

Denmark
Imperial College London
Pfizer

Completed

Changes in Cerebral Function in Treatment Naive HIV-1 Infected Subjects Commencing Either Boosted Atazanavir With Truvada or Boosted Darunavir With Maraviroc and Kivexa (CogUK)

HIV | Impaired Cognition

United Kingdom
Royal Devon and Exeter NHS Foundation Trust
University of Exeter

Completed

Increasing Mitochondrial Function on Skeletal Muscle Performance in Older Men (Rejuvenate)

Impaired Mitochondrial Function, Muscle Performance

United Kingdom
NXTech
Kansas State University

Completed

Boost Study 21270 (Cognition)

Cognitive Function Abnormal

United States
Astellas Pharma Inc

Completed

Pharmacokinetics Study in Patients With Impaired Hepatic Function

Patients With Impaired Hepatic Function

Japan
Todd Schroeder
Southern California Clinical and Translational Science Institute

Completed

Resistance Training and Neuroimaging (RTNI)

Cognitive Decline | Cerebrovascular Function

United States
Chinese University of Hong Kong

Completed

Air Purifier to Improve Endothelial Function and Carotid Intima Thickness

Cognitive Impairment | Endothelial Function

Hong Kong
KK Women's and Children's Hospital
Singapore Institute for Clinical Sciences

Active, not recruiting

Exposure to General Anaesthesia in Infancy and Neurocognitive Development (EGAIN)

Impaired Cognition | Central Nervous System Complications of Anesthesia

Singapore
Tel-Aviv Sourasky Medical Center

Unknown

The Differential Pattern of Deposition of Nano Particles in the Airways of Exposed Workers (Nanoexposure)

Inadequate or Impaired Respiratory Function
UCB Biopharma S.P.R.L.

Terminated

A Pharmacokinetic Study of Padsevonil in Study Participants With Either Normal or Moderately Impaired Hepatic Function

Impaired Hepatic Function | Healthy Study Participants

United States
First Affiliated Hospital of Chongqing Medical...

Unknown

Effect of Subanesthetic Dose of Ketamine Combined With Propofol on Cognitive Function in Depressive Patients Undergoing Electroconvulsive Therapy

Depressive Symptoms | Impaired Cognition | Electroconvulsive Therapy

China
Pusan National University Yangsan Hospital

Completed

Effects of Photobiomodulation on Changes in Cognitive Function and rCBF in MCI

Mild Cognitive Impairment | Cognitive Function | Regional Cerebral Blood Flow

Korea, Republic of
Science and Research Centre Koper
Albert Einstein College of Medicine; University of Primorska; Vrije Universiteit...

Completed

Effects of Cognitive Intervention on Cognition, Mobility and Brain Electrocortical Activity (GIBKOP)

Cognitive Impairment | Aging | Cognitive Decline | Motor Coordination or Function

Slovenia
Central South University

Unknown

A Double-blind, Placebo-controlled Trial of Donepezil Adjunctive Treatment for Cognitive Impairment in Schizophrenia

Schizophrenia | Impaired Cognition

China
Astellas Pharma Inc

Completed

Pharmacokinetics Study in Patients With Impaired Renal Function and Subjects With Normal Renal Function

Patients With Impaired Renal Function

Japan
Stealth BioTherapeutics Inc.

Completed

A Phase 1 Study Investigating the Safety and Pharmacokinetics of Repeat-dose Intravenous Infusion of MTP-131 in Subjects With Impaired Renal Function

Normal and Impaired Renal Function

United States
Actinogen Medical
AXIOM Real Time Metrics

Active, not recruiting

Xanamem® in Adults With Major Depressive Disorder and Impaired Cognition (XanaCIDD)

Cognitive Impairment | Major Depressive Disorder | MDD

Australia, United Kingdom
University of Missouri, Kansas City
Truman Medical Center; American Association of Critical-Care Nurses; St. Luke...

Unknown

Simultaneous Recumbent Cycling and Cognitive Training

Delirium | Impaired Cognition

United States
FORUM Pharmaceuticals Inc
Syneos Health; NeuroCog Trials, Inc.

Completed

Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy

Schizophrenia | Impaired Cognition

United States, Australia, Poland, Ukraine, Germany, Spain, Argentina, Serbia, Canada, Singapore, Russian Federation, Brazil, Mexico
Jiangsu HengRui Medicine Co., Ltd.

Unknown

A Study to Evaluate the Pharmacokinetics of Apatinib in Subjects With Impaired Renal Function

Subjects With Impaired Renal Function and Healthy Subjects
Astellas Pharma Inc

Completed

ASP8825 - Pharmacokinetics Study in Patients With Impaired Renal Function and Haemodialysis

Patients With Impaired Renal Function and Haemodialysis

Japan
University of Seville

Unknown

Effect of Strength Training on Executive Functions in Elderly People With Mild Cognitive Impairment (Executive-19)

Executive Function | Strength Training

Spain
Cengiz KAYA
Ondokuz Mayıs University

Completed

The Effect of Retrobulbar Block for Eye Surgery on Brain Oxygenation and Cognitive Functions in Elderly Patients

Vitreoretinal Surgery | Cognitive Function Abnormal | Intraoperative Monitoring

Turkey
FORUM Pharmaceuticals Inc
Syneos Health

Completed

A 26-Week Extension Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy

Schizophrenia | Impaired Cognition

United States, Ukraine, United Kingdom, Germany, Spain, Argentina, Canada, Singapore, Russian Federation, Italy, Mexico, Colombia, Australia, Belgium, Poland, Romania
FORUM Pharmaceuticals Inc
Syneos Health; NeuroCog Trials, Inc.

Completed

Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy

Schizophrenia | Impaired Cognition

United States, Ukraine, United Kingdom, Poland, Romania, Russian Federation, Italy, Mexico, Colombia, Argentina, Australia, Brazil
University School of Physical Education in Wroclaw

Active, not recruiting

Effects of the EEG-neurofeedback on Cognitive Function

Cognitive Function | Executive Function

Poland
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDK378 Pharmacokinetics

Normal Hepatic Function | Impaired Hepatic Function

United States
University of California, San Francisco
Washington University School of Medicine; Northwestern University; National Institute... and other collaborators

Completed

Mindfulness Based Stress Reduction for Older Adults With HIV Associated Neurocognitive Disorders

HIV Infection | Impaired Cognition

United States
Maastricht University
Wageningen University and Research; Top Institute Food and Nutrition; Netherlands...

Terminated

The Effect of Fish Oils With Dairy or Plant Based Lipids on Mitochondrial and Physical, and Cognitive Function, in Elderly Humans

Cognitive Function | Ageing | Physical Function | Mitochondrial Function

Netherlands
University of Exeter
Royal Devon and Exeter NHS Foundation Trust

Terminated

Assessing the Effects of Increased Mitochondrial Function Exercise Training on Muscle Performance (Rejuvenate2)

Impaired Mitochondrial Function, Muscle Performance

United Kingdom
Amsterdam UMC, location VUmc

Completed

A Study on Better Cognitive Functioning Through Braintraining on the Internet (BrainFit)

Depression | Impaired Cognition | Alteration in Cognition | Late Life Mood Disorder | Alteration in Mood

Netherlands
Fundacion para la Investigacion y Formacion en...

Completed

Physical Activity to Patients With Dementia and Their Caregivers. (AFISDEMyF)

Impaired Cognition

Spain
Universidade Metodista de Piracicaba

Completed

Positive Airway Pressure Versus Breathing Exercises With Load Inspiratory in Patients Undergoing Bariatric Surgery

Inadequate or Impaired Respiratory Function

Brazil
University Hospital, Geneva

Completed

Physical Exercise and Jaques-Dalcroze Eurhythmics: Effects on Physical and Cognitive Functions, and Falls in Seniors (EPHYCOS)

Cognitive Function | Falls | Physical Function

Switzerland
Universidad Complutense de Madrid
Ministerio de Economía y Competitividad, Spain

Completed

Attentional Bias Modification Through Eye-tracker Methodology (ABMET) (ABMET)

Depression | Cognitive Deficits | Alteration of Cognitive Function

Spain
National Cheng Kung University

Completed

Driving Evaluation and Fitness for Persons With Cognitive Impairments

Mild Cognitive Impairment | Driving Impaired | Dementia, Mild | Drive

Clinical Trials on Impaired Cognitive Function

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