Clinical Trials on Intervertebral Disc Degeneration in Singapore

Total 40 results

Singapore National Eye Centre
Bayer

Completed

An Open Label-study to Compare the Efficacy of Aflibercept Monotherapy for Polypoidal Choroidal Vasculopathy

Age Related Macular Degeneration | Polypoidal Choroidal Vasculopathy

Singapore
National University of Singapore
National University Hospital, Singapore; Ministry of Education, Singapore

Active, not recruiting

Impact of Regular Consumption of Grapes on Eye Health in Singapore Older Adults

Age-related Macular Degeneration | Eye Health

Singapore
Singapore National Eye Centre

Completed

Optical Coherence Tomography Imaging of the Posterior Segment in High Myopia.

Glaucoma | Myopia | Maculopathy

Singapore
Singapore National Eye Centre
Santen Pharmaceutical Co., Ltd.; Singapore Eye Research Institute

Unknown

Diabetic Macular Edema Asian Response (DEAR) Study: Biomarkers for Response to Aflibercept in Asian Patients With Center Involving DME

Diabetic Macular Edema

Singapore
Singapore Eye Research Institute
University of Melbourne; Curtin University; Singapore National Eye Centre; Ministry...

Unknown

Living Successfully With Chronic Eye Diseases (ADAPT-LAH)

Glaucoma | Diabetic Retinopathy | Age-related Macular Degeneration | Low Vision | Chronic Diseases

Singapore
Essilor International

Active, not recruiting

Clinical Evaluation of a Myopia Control Lens in Slowing Myopia Progression

Myopia | Myopia, Progressive

Singapore
Novartis Pharmaceuticals

Completed

UNcovering the Difference Between Ranibizumab and Aflibercept, Focusing on Systemic Anti-vascular Endothelial Growth Factor (VEGF) Effects in Patients With neovascuLar Age-related Macular Degeneration (AMD) (UNRAVEL)

Neovacular Age-related Macular Degeneration

Taiwan, Thailand, Israel, Korea, Republic of, Philippines, Singapore, Malaysia
National Neuroscience Institute
Hovid Berhad

Recruiting

Tocotrienols in Parkinson's Disease (PD)

Parkinson Disease | Neuro-Degenerative Disease

Singapore
Allergan

Completed

A Study of the Safety and Efficacy of a New Treatment for Diabetic Macular Edema

Diabetic Macular Edema

United Kingdom, Taiwan, Colombia, Korea, Republic of, Singapore, Brazil, New Zealand, Poland, Hungary, Italy, India, France, United States, Canada
Hoffmann-La Roche

Recruiting

A Study of the Efficacy, Safety, and Pharmacokinetics of A 36-Week Refill Regimen for the Port Delivery System With Ranibizumab in Patients With Neovascular Age-Related Macular Degeneration (Velodrome)

Neovascular Age-related Macular Degeneration (nAMD)

Belgium, Korea, Republic of, Germany, Spain, United Kingdom, Australia, Italy, Argentina, Israel, Austria, Brazil, France, Singapore, Switzerland, Taiwan, Turkey
Bayer
Regeneron Pharmaceuticals

Completed

Aflibercept in Polypoidal Choroidal Vasculopathy (PLANET)

Neovascular Macular Degeneration

Taiwan, Hong Kong, Korea, Republic of, Japan, Singapore, Australia, Hungary, Germany
Chengdu Kanghong Biotech Co., Ltd.

Terminated

Efficacy and Safety Trial of Conbercept Intravitreal Injection for Neovascular AMD (PANDA-1)

Neovascular Age-related Macular Degeneration

United States, Argentina, Australia, Austria, Belgium, Canada, Chile, Colombia, Germany, Hong Kong, Lithuania, Mexico, Netherlands, New Zealand, Peru, Philippines, Poland, Portugal, Singapore, Spain, Switzerland, Taiwan
Shanghai Henlius Biotech

Active, not recruiting

A Phase 3 Study to Compare the Efficacy and Safety of HLX04-O With Ranibizumab in Subjects With wAMD

Age Related Macular Degeneration

United States, Singapore, Spain, Germany, Slovakia, China, Hungary, Australia, Bulgaria, Poland, Latvia, Czechia, France, Italy, Serbia
Visioneering Technologies, Inc

Recruiting

Progressive Myopia Treatment Evaluation for NaturalVue Multifocal Contact Lens Trial (PROTECT)

Myopia

United States, Canada, Hong Kong, Singapore
Hoffmann-La Roche

Active, not recruiting

A Study to Evaluate the Long-Term Safety and Tolerability of Faricimab in Participants With Neovascular Age-Related Macular Degeneration (AVONELLE-X)

Neovascular Age-related Macular Degeneration

United States, Korea, Republic of, United Kingdom, Japan, Canada, Turkey, Argentina, Australia, Denmark, France, Germany, Hungary, Italy, Poland, Spain, Singapore, Austria, Brazil, Hong Kong, Israel, Portugal, Russian Federation, Ta... and more
Allergan

Completed

A Study of the Safety and Efficacy of a New Treatment for Macular Edema Resulting From Retinal Vein Occlusion

Macular Edema | Retinal Vein Occlusion

United States, Poland, United Kingdom, Colombia, Spain, Korea, Republic of, Singapore, Brazil, New Zealand, Hong Kong, Italy, Canada, India
Novartis Pharmaceuticals

Completed

Visual Outcome in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy (PCV) Treated With Either Ranibizumab as Monotherapy or Combined With Verteporfin Photodynamic Therapy (vPDT) (EVEREST II)

Age-related Macular Degeneration | Polypoidal Choroidal Vasculopathy

Japan, Taiwan, Hong Kong, Singapore, Thailand, Korea, Republic of, Malaysia
Bayer
Regeneron Pharmaceuticals

Active, not recruiting

Study of the Effects of High Dose Aflibercept Injected Into the Eye of Patients With an Age-related Disorder That Causes Loss of Vision Due to Growth of Abnormal Blood Vessels at the Back of the Eye (PULSAR)

Neovascular Age-Related Macular Degeneration

United States, Spain, Korea, Republic of, Czechia, Japan, Singapore, China, Serbia, Lithuania, Taiwan, Australia, Estonia, Austria, Israel, France, Italy, Switzerland, Slovakia, Ukraine, Bulgaria, Portugal, Latvia, Canada, Hungary, Arge... and more
Hoffmann-La Roche

Completed

A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Neovascular Age-Related Macular Degeneration (LUCERNE)

Wet Macular Degeneration

Korea, Republic of, United States, China, Argentina, Australia, Denmark, France, Germany, Italy, Poland, Spain, Singapore, Austria, Brazil, Hong Kong, Hungary, Portugal, Russian Federation, Taiwan, Turkey, Bulgaria
Hoffmann-La Roche

Recruiting

A Real-World Study to Gain Clinical Insights Into Roche Ophthalmology Products (VOYAGER)

Diabetic Macular Edema | Neovascular Age-related Macular Degeneration

Germany, Croatia, Japan, United Kingdom, Spain, United States, Italy, Switzerland, Canada, France, Australia, Singapore, Israel, Puerto Rico, United Arab Emirates, Bulgaria, Chile, Czechia
Allergan

Completed

A Safety and Efficacy Study of Abicipar Pegol in Participants With Neovascular Age-related Macular Degeneration (CEDAR)

Macular Degeneration

Spain, United States, Korea, Republic of, Israel, Singapore, Argentina, Germany, France, Czechia, Austria, Philippines, Switzerland, Chile, Colombia, Hong Kong, Latvia, New Zealand
Novartis

Completed

Efficacy and Safety of Ranibizumab (Intravitreal Injections) in Patients With Visual Impairment Due to Diabetic Macular Edema (REVEAL)

Diabetic Macular Edema

Hong Kong, Taiwan, Singapore, Korea, Republic of, China, Japan
Hoffmann-La Roche

Recruiting

Vamikibart in Participants With Uveitic Macular Edema (Sandcat)

Uveitic Macular Edema

India, United States, Japan, Australia, Singapore, Turkey, Argentina, Czechia, Spain, France, Germany, Switzerland
Novartis Pharmaceuticals

Completed

To Assess the Efficacy and Safety of Intravitreal Ranibizumab in People With Vision Loss Due to Macular Edema

Macular Edema (ME)

Russian Federation, Turkey, United Kingdom, Belgium, Australia, Hungary, Switzerland, Germany, Italy, Korea, Republic of, Israel, Spain, France, Latvia, Netherlands, Slovakia, Czech Republic, Singapore, Canada
Bayer
Regeneron Pharmaceuticals

Completed

Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration (AMD) (VIEW 2)

Macular Degeneration

Belgium, Israel, Italy, Spain, Korea, Republic of, Switzerland, Germany, Portugal, Japan, France, Australia, Netherlands, India, Austria, Brazil, Poland, United Kingdom, Singapore, Hungary, Latvia, Mexico, Czech Republic, Colombia, Ar... and more
Hoffmann-La Roche

Completed

A Study to Evaluate the Long-Term Safety and Tolerability of Faricimab in Participants With Diabetic Macular Edema (Rhone-X)

Diabetic Macular Edema

United States, Korea, Republic of, United Kingdom, Brazil, Japan, Canada, Argentina, Australia, Austria, Denmark, France, Germany, Hungary, Italy, Poland, Slovakia, Spain, Singapore, Czechia, Hong Kong, Israel, Portugal, Russian Federation and more
Hoffmann-La Roche

Completed

A Study to Evaluate the Efficacy and Safety of Faricimab (RO6867461) in Participants With Diabetic Macular Edema (RHINE)

Diabetic Macular Edema

Korea, Republic of, United States, United Kingdom, Brazil, China, Canada, Argentina, Australia, Denmark, France, Italy, Poland, Spain, Germany, Singapore, Czechia, Hong Kong, Portugal, Russian Federation, Taiwan, Hungary, Switzerland and more
DePuy International

Active, not recruiting

Survivorship of Attune Primary Total Knee Prosthesis

Noninflammatory Degenerative Joint Disease

United States, Hong Kong, Malaysia, United Kingdom, Australia, Austria, Belgium, Canada, Germany, New Zealand, Singapore, Switzerland, Korea, Republic of
Novartis Pharmaceuticals

Completed

A Study of the Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KITE)

Diabetic Macular Edema

Czechia, India, Russian Federation, Taiwan, Turkey, Lebanon, Denmark, Estonia, France, Germany, Hungary, Korea, Republic of, Latvia, Lithuania, Bulgaria, Norway, Belgium, Malaysia, Sweden, Slovakia, Singapore, Poland, Switzerland
Novartis Pharmaceuticals

Completed

Observe the Effectiveness and Safety of Ranibizumab in Real Life Setting (LUMINOUS)

Diabetic Macular Edema | Retinal Vein Occlusion | Wet Age Related Macular Degeneration | Wet Age Related Macular Degeneration, Diabetic Macular Edema, Retinal Vein Occlusion

Spain, China, Colombia, Korea, Republic of, Belgium, Greece, Japan, Russian Federation, Turkey, United Kingdom, Egypt, Germany, Australia, Canada, France, Austria, Hong Kong, Hungary, Israel, Netherlands, Peru, Singapore, Slovakia, Sl... and more
Bayer
Regeneron Pharmaceuticals

Completed

VEGF Trap-Eye in Choroidal Neovascularization Secondary to Pathologic Myopia (mCNV) (Myrror)

Myopia, Pathological

Japan, Taiwan, Hong Kong, Korea, Republic of, Singapore
Hoffmann-La Roche
Chugai Pharmaceutical

Completed

A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Macular Edema Secondary to Branch Retinal Vein Occlusion (BALATON)

Macular Edema | Branch Retinal Vein Occlusion

United States, Korea, Republic of, Brazil, Japan, United Kingdom, China, Argentina, Australia, France, Germany, Hungary, Italy, Poland, Spain, Singapore, Austria, Czechia, Hong Kong, Israel, Portugal, Russian Federation, Taiwan
Alexion

Completed

Copper Concentration & Histopathologic Changes in Liver Biopsy in Participants With Wilson Disease Treated With ALXN1840

Wilson Disease

United Kingdom, New Zealand, United States, Denmark, Russian Federation, Spain, Singapore
Hoffmann-La Roche
Chugai Pharmaceutical

Completed

A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Macular Edema Secondary to Central Retinal or Hemiretinal Vein Occlusion (COMINO)

Central Retinal Vein Occlusion | Macular Edema | Hemiretinal Vein Occlusion

United States, Korea, Republic of, Brazil, Japan, United Kingdom, China, Argentina, Australia, France, Hungary, Italy, Poland, Spain, Singapore, Austria, Czechia, Germany, Hong Kong, Israel, Portugal, Russian Federation, Taiwan
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab in Patients With Visual Impairment Due to Choroidal Neovascularization Secondary to Pathologic Myopia

Pathological Myopia

Germany, India, Japan, Turkey, Austria, Switzerland, Italy, Lithuania, Hungary, France, Slovakia, United Kingdom, Korea, Republic of, Portugal, Hong Kong, Canada, Singapore, Spain, Latvia, Poland
Alexion

Terminated

Efficacy and Safety of ALXN1840 Administered for 48 Weeks Versus Standard of Care in Participants With Wilson Disease

Wilson Disease

United States, France, Germany, Spain, Canada, Singapore, Poland, Denmark, Hungary, Australia, Austria, Czechia, Hong Kong, Israel, Japan, Korea, Republic of, New Zealand, Russian Federation, Serbia, Taiwan, Turkey, United Kingdom
TauRx Therapeutics Ltd

Completed

Safety and Efficacy Study Evaluating TRx0237 in Subjects With Behavioral Variant Frontotemporal Dementia (bvFTD)

Behavioral Variant Frontotemporal Dementia (bvFTD)

United States, Australia, Canada, Croatia, Poland, Netherlands, United Kingdom, Spain, Germany, Italy, Romania, Singapore
Mandos LLC

Completed

VTS-270 to Treat Niemann-Pick Type C1 (NPC1) Disease

Niemann-Pick Disease, Type C

United States, Australia, United Kingdom, Germany, France, New Zealand, Singapore, Spain, Turkey
Mandos LLC

Terminated

Adrabetadex to Treat Niemann-Pick Type C1 (NPC1) Disease

Niemann-Pick Disease, Type C

United States, Australia, United Kingdom, Turkey, Switzerland, Germany, New Zealand, Singapore, France
TauRx Therapeutics Ltd

Terminated

Open-Label Study of Leuco-methylthioninium Bis(Hydromethanesulfonate) (LMTM) in Subjects With Alzheimer's Disease or Behavioral Variant Frontotemporal Dementia (bvFTD)

Alzheimer's Disease | Behavioral Variant Frontotemporal Dementia

Korea, Republic of, United States, Spain, Taiwan, Canada, Belgium, Malaysia, United Kingdom, Australia, Singapore, Croatia, Finland, France, Germany, Netherlands, Romania, Russian Federation

Clinical Trials on Intervertebral Disc Degeneration in Singapore

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