Clinical Trials on Major Bone Articular Surface Loss

Total 626 results

Major Extremity Trauma Research Consortium

Completed

Outcomes Following Severe Distal Tibia, Ankle and/or Foot Trauma: Comparison of Limb Salvage Versus Transtibial Amputation Protocol (OUTLET)

Severe Distal Tibia Injury | Severe Ankle Injury | Severe Foot Injury | Major Soft Tissue Loss | Major Bone Articular Surface Loss | Major Ankle Articular Surface Loss

United States
Frederiksberg University Hospital

Completed

A Clinical Evaluation of Wear Couples in THA

Prosthesis Survival | Articular Bearing Surface Wear of Prosthetic Joint | Wear of Articular Bearing Surface of Prosthetic Joint
Reinier Haga Orthopedisch Centrum

Recruiting

Migration of CS vs CR Insert in TKA Using RSA (CS vs CR RSA)

Wear of Articular Bearing Surface of Prosthetic Joint | Migration of Implant

Netherlands
Zimmer Biomet

Recruiting

Clinical Outcomes Study of the Nexel Total Elbow

Post-traumatic Arthritis | Degenerative Arthritis | Elbow Joint Destruction | Post-traumatic Lesions | Ankylosed Joints | Advanced Rheumatoid Arthritis | Joint Instability or Loss of Motion | Acute Comminuted Articular Fracture of Elbow Joint Surfaces | Bone Loss Contributing to Elbow Instability | Bilateral...

United States, Australia, Finland, France, Germany, Italy, Netherlands, United Kingdom
National Science Council, Taiwan

Completed

Validation of Muscle Strength Testing for Pectoralis Major

Muscle Strength | Surface EMG | Pectoralis Major | Force Measurement

Taiwan
Wake Forest University Health Sciences
United States Department of Defense

Not yet recruiting

Single Versus Dual Implant Fixation of Distal Femur Fractures (PRORP)

Articular Fractures

United States
University of Tennessee

Unknown

Sinus Tarsi Versus Extensile Lateral Approach for Calcaneus Fractures

Intra-articular Fractures

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Treatment of Intra-articular Fractures of the Mandibular Condyle (FIAC)

Intra-articular Fracture of the Mandibular Condyle

France
Vanderbilt University Medical Center

Terminated

Steroid Administration for Articular Fractures of the Elbow (SAFE Trial) (SAFE)

Elbow Fracture

United States
Mohamed Mahmoud Dohiem

Recruiting

Digital VS. Conventional Ear Impression

Patient Loss His Ear and Need Auricular Prosthesis

Egypt
Prisma Health-Upstate
Orthopaedic Trauma Association

Completed

Use of Continuous Passive Motion in the Post-Operative Treatment of Intra-articular Knee Fractures

Intra-articular Knee Fractures

United States
Maastricht University Medical Center

Not yet recruiting

Permissive Weight Bearing in Displaced Intra-articular Calcaneal Fractures (PIONEER)

Trauma Injury | Calcaneus Fracture | Displaced Intra-Articular Fracture of Calcaneus (Diagnosis)
Vivantes Netzwerk für Gesundheit GmbH

Unknown

Percutaneous Punch Biopsy for Diagnosis of Septic and Aseptic Prosthetic Joint Failure (SHARP)

Prosthetic Joint Infection | Infections Joint Prosthetic | Wear of Articular Bearing Surface of Internal Prosthetic Joint | Infection Prosthetic | Prosthetic Pain

Germany
Bergen Orthopedic Study Group

Completed

Results at 10 to 14 Years After Microfracture in the Knee

Articular Chondral Defect

Norway
The University of Texas Health Science Center,...

Terminated

Hemostasis in Kocher-Langenbeck Approaches for Acetabular Surgery Using a Topical Surgical Hemostat (Vitagel)

Intra-Articular Fractures | Acetabulum | Fracture Fixation

United States
Aesculap Biologics, LLC

Recruiting

NOVOCART 3D Treatment Following Microfracture Failure

Articular Cartilage Defect

United States
Vericel Corporation

Completed

Superiority of MACI® Versus Microfracture Treatment in Patients With Symptomatic Articular Cartilage Defects in the Knee (SUMMIT)

Articular Cartilage Defect

Netherlands, Norway, France, Czechia, Sweden, Poland, United Kingdom
Derince Training and Research Hospital

Completed

Comparison of Intra-articular Dexmedetomidine and Magnesium in Postoperative Pain

Postoperative Pain | Dexmedetomidine | Magnesium Sulfate | Intra-articular Injection

Turkey
Instituto Nacional de Rehabilitacion
National Council of Science and Technology, Mexico

Completed

Arthroscopic Autologous Chondrocyte Implantation Versus Microfractures

Tear; Knee, Cartilage, Articular

Mexico
Sewon Cellontech Co., Ltd.

Unknown

the Efficacy and Safety of a Modified Microfracture Using Collagen Compared to Those of a Simple Microfracture in Ankle

Defect of Articular Cartilage

Korea, Republic of
Zimmer Biomet

Active, not recruiting

Persona Partial Knee Clinical Outcomes Study

Osteoarthritis | Avascular Necrosis | Traumatic Arthritis | Conditional Tibial Condyle or Plateau Fractures | Conditional Revision of the Articular Surface

United Kingdom, Spain, United States, Italy, Sweden, Belgium, Austria, France, Germany, Switzerland
McMaster University
Geistlich Pharma AG

Recruiting

AMIC Compared With Microfracture for Focal Articular Cartilage Damage of the Hip (REPAIR)

Hip Arthroscopy | Articular Cartilage Defect | Microfractures

Canada
Duke University

Recruiting

Intra Articular Ankle Fractures

Intra-Articular Fractures

United States
University of Calgary
Orthopaedic Trauma Association; AO North America

Completed

Comparative Study of Fixation or Fusion of Calcaneal Fractures (Sanders IV)

Fractures, Comminuted | Fracture Fixation, Internal

Canada
TiGenix n.v.

Completed

RCT of ChondroCelect® (in an ACI Procedure) vs Microfracture in the Repair of Cartilage Defects of the Knee (TIGACT01)

Articular Cartilage Lesion of the Femoral Condyle

Belgium, Croatia, Germany, Netherlands
Ross Leighton
Biocomposites Ltd

Completed

Management of Traumatic Bone Defects in Tibial Plateau Fractures With Antibiotic-Impregnated Biodegradable Calcium Sulfate Beads: A Prospective Clinical Trial

Tibial Fractures | Intra-Articular Fractures | Fracture Fixation, Internal

Canada
University of Colorado, Denver
Stanford University; University of Kentucky

Recruiting

Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects

Degenerative Lesion of Articular Cartilage of Knee

United States
Alexandria University
Lehigh University

Completed

Bioactive Glass (Sol-gel) for Alveolar Bone Regeneration After Surgical Extraction

Bone Loss | Horizontal Alveolar Bone Loss | Vertical Alveolar Bone Loss

Egypt
Oligo Medic Pty Ltd
Mobius Medical Pty Ltd.

Recruiting

A Comparison of JointRep® and Microfracture in Repair of Cartilage Lesions on the Femoral Condyle or Trochlea, (JMAC)

Chondral Defect | Articular Cartilage Disorder of Knee | Articular Cartilage Defect

Australia, Canada
Robert Jones and Agnes Hunt Orthopaedic and District...

Terminated

Protected Versus Early Weight Bearing Post Microfracture Surgery

Defect of Articular Cartilage

United Kingdom
University Hospital, Angers
Ministry of Health, France

Unknown

Restoration of the Radial Length in Compound Wrist Fractures Using Anterior Locking Plates

Articular Displaced Fractures of the Lower End of the Radius

France
Neva Electromagnetics, LLC
Massachusetts General Hospital

Unknown

Radio-frequency Identification (RFID) Osteoporosis Pilot Study

Bone Loss, Age Related | Age-Related Bone Loss
Vericel Corporation

Recruiting

A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee (PEAK)

Chondral Defect | Articular Cartilage Disorder of Knee | Articular Cartilage Defect | Osteochondritis Dissecans (OCD)

United States
Sewon Cellontech Co., Ltd.

Unknown

Comparison of Efficacy and Safety of Microfracture and Modified Microfracture

Osteoarthritis | Defect of Articular Cartilage | Traumatic Arthritis

Korea, Republic of
Fondren Orthopedic Group L.L.P.
InGeneron, Inc.

Completed

Use of Cell Therapy to Enhance Arthroscopic Knee Cartilage Surgery

Articular Cartilage Defect Grade III or IV of the Knee

United States
RWTH Aachen University

Completed

Hyperbaric Oxygen Therapy in Calcaneal Intraarticular Fractures: Can it Decrease the Soft-tissue Complication Rate? (HOCIF)

Wound Healing | Microcirculation

Germany
Piramal Healthcare Canada Ltd
Smith & Nephew, Inc.; Global Research Solutions

Terminated

Randomized Evaluation of BST-CarGel Versus Microfracture Alone On Recovery From Distal Femoral Cartilage Lesions (RECORD)

Degenerative Lesion of Articular Cartilage of Knee | Traumatic; Lesion

Spain, France, Australia, Canada, Germany, Switzerland, United Kingdom
Tetec AG

Active, not recruiting

Phase III Study to Evaluate Safety and Effectiveness of NOVOCART 3D Plus vs. Microfracture in Knee Cartilage Defects (N3D)

Traumatic Articular Cartilage Defects in the Knee Joint

United Kingdom, Hungary, Czechia, Germany, Lithuania, Austria, France, Latvia, Poland, Switzerland
Faculty of Dental Medicine for Girls

Enrolling by invitation

Stability, Marginal Bone Loss and Occlusal Load Analysis of PEEK Abutment Supported on Short Implant

Marginal Bone Loss and Loss of Osteointegration of Short Implant

Egypt
University of Santiago de Compostela
Mozo Grau Ticare Implants

Recruiting

Influence of the Design of the Transmucosal Abutment on the Periimplant Bone Level

Peri-implant Marginal Bone Loss | Peri-implant Bone Level | Transmucosal Abutment Design | Peri-implant Bone Loss

Spain
Dr. Soetomo General Hospital
Dr. Ramelan Naval Hospital; Airlangga University Hospital; Sidoarjo General Hospital and other collaborators

Recruiting

Freeze-dried Bovine Hydroxyapatite/Secretome Composite for Bone Defects

Bone Loss

Indonesia
Mansoura University

Completed

Different Implant Positions for Implant Retained Mandibular Overdenture

Bone Loss

Egypt
University of Valencia
Juan Carlos Bernabeu Mira; Miguel Peñarrocha Diago

Completed

Comparison Between High-speed Drilling With Irrigation and Low-speed Drilling With Irrigation

Bone Loss

Spain
Worcester Polytechnic Institute
Northwestern University

Completed

A Prospective Study of Human Bone Adaptation Using a Novel in Vivo Loading Model

Bone Loss
Mansoura University

Completed

Effect of Block-out Spacer to Pick up Locator Attachments to Retain Overdenture: Peri-implant and Alveolar Bone Changes

Bone Loss

Egypt
Imam Abdulrahman Al Faisal Hospital

Unknown

Socket Preservation for Dental Implant Site Development.

Bone Loss

Saudi Arabia
Aga Khan University

Completed

Does Surgical-approach Affect Outcome After Fixation of Intra-articular Fractures of Distal Humerus?

Distal Humerus Fracture
University of Alabama at Birmingham

Not yet recruiting

Release Kinetics of rhBMP-2 Using E-PRF as an Autologous Carrier: An In Vitro Analysis

Bone Loss

United States
Assiut University

Not yet recruiting

Bifocal vs Trifocal External Bone Transport by Ilizarov Ring External Fixator in Lower Limbs

Bone Loss
Mansoura University

Completed

Radiographic Evaluation of All-on-4 Implant Prosthesis With Different Materials and Bar Construction Techniques

Bone Loss

Egypt

Clinical Trials on Major Bone Articular Surface Loss

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Dominican Republic

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations