Clinical Trials on Malaria, Falciparum

Total 1330 results

London School of Hygiene and Tropical Medicine
Medical Research Council Unit, The Gambia

Terminated

Evaluation of the Safety of Primaquine in Combination With Dihydroartemisinin-piperaquine in G6PD Deficient Males in The Gambia (SAFEPRIM-II)

Malaria

Gambia
University of Nottingham
University of Benin

Unknown

A Comparison of Diagnostic Approaches for Malaria and Pneumonia

Pneumonia | Malaria

Nigeria
London School of Hygiene and Tropical Medicine
Medical Research Council; National Malaria Control Programme, The Gambia

Completed

Lapdap and Coartemether for Uncomplicated Malaria

Malaria

Gambia
Foundation for Innovative New Diagnostics, Switzerland
Ministry of Health, Senegal; Institut Pasteur de Dakar

Recruiting

Validation of a CDSA Strategy to Reduce Antibiotic Prescription in Senegal

Pneumonia | Diarrhea | Malaria | Dengue | Acute Febrile Illness | Influenza -Like Illness

Senegal
London School of Hygiene and Tropical Medicine
University Medical Center Nijmegen; Centre national de recherche et de formation...

Completed

Safety of Primaquine + Artemether-lumefantrine in G6PD Deficient Males With an Asymptomatic Malaria Infection (SAFEPRIM)

Malaria

Burkina Faso
London School of Hygiene and Tropical Medicine
Wellcome Trust; Centre Muraz; Development Media International; Planet Wheeler Foundation

Completed

Can Mass Media Campaigns Reduce Child Mortality

Pneumonia | Malaria | Breastfeeding | Diarrhoea | Under-nutrition

Burkina Faso
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit; CSK Research Solutions

Recruiting

Star Homes Project 2 (SHP2)

Malaria | Diarrhoea;Acute | Respiratory Tract Infection Acute

Tanzania
Centre Hospitalier Intercommunal Creteil

Completed

Perceptions, Representations and Experiences of Malaria Prophylaxis in Patients Born in Endemic Areas and Living in France. (PREPAP)

Malaria | Disease, Infectious | Travel-Associated Infections

France
London School of Hygiene and Tropical Medicine
Malaria Research and Training Center, Bamako, Mali; Institut de Recherche en...

Completed

A Trial of Seasonal Malaria Chemoprevention Plus Azithromycin in African Children (SMCAZ)

Malaria | Respiratory Infections

Burkina Faso, Mali
JSI Research & Training Institute, Inc.
Bill and Melinda Gates Foundation; Federal Ministry of Health, Nigeria

Completed

The Impact of Sulphadoxine-Pyrimethamine Use At Scale on Newborn Outcomes in Nigeria (MIPP-NG)

Malaria | Stillbirths
University of Oxford
Mahidol Oxford Tropical Medicine Research Unit

Recruiting

Village Malaria Worker Expansion (CAM-VMW)

Febrile Illness

Cambodia
Menzies School of Health Research
International Centre for Diarrhoeal Disease Research, Bangladesh

Completed

A Study to Assess Safety of Current Standard Malaria Treatment and an Assessment of G6PD Status in South-east Bangladesh

Malaria
Sysmex Europe GmbH
Radboud University Medical Center; Clinical Research Unit of Nanaro (CRUN),... and other collaborators

Completed

Optimizing Sysmex Technology as an Innovative Tool to Differentiate Between Malaria (PALUdism) and BACterial Infections in a Malaria Endemic Region (PALUBAC)

Tropical Infectious Diseases

Burkina Faso
National Institute of Allergy and Infectious Diseases...

Completed

Medical Implications of Coinfection With Malaria and Filariasis Parasites

Malaria | Filariasis

Mali
Menzies School of Health Research
University of Medicine 2, Yangon

Completed

Empirical ANtibiotic THErapy in Adults Hospitalised With Malaria (ANTHEM)

Sepsis | Bacteremia | Malaria

Myanmar
World Health Organization

Completed

Home Management of Malaria and Pneumonia (HMM/P)

Pneumonia | Malaria

Burkina Faso
National Institute of Allergy and Infectious Diseases...

Completed

Defining Skin Immunity of a Bite of Key Insect Vectors in Humans

Malaria | Leishmaniasis | Dengue | Chikungunya | Zika

United States
Medecins Sans Frontieres, Netherlands

Completed

Effect of Ready to Use Therapeutic Food (RUTF) Supplement After an Episode of Malaria Falciparum on Weight

Weight Loss | Malaria | Weight Gain | Convalescence

Congo
National Institute of Allergy and Infectious Diseases...

Completed

Collection of Blood From Persons With Hemoglobin and Erythrocyte Polymorphisms for Laboratory Malaria Research

Hemoglobin Mutations | Erythrocyte Variants

United States
Colorado State University
Institut de Recherche en Sciences de la Sante, Burkina Faso; Centre Muraz; Ministère...

Completed

Repeat Ivermectin Mass Drug Administrations for Control of Malaria: a Pilot Safety and Efficacy Study (RIMDAMAL)

Malaria | Lymphatic Filariasis

United States, Burkina Faso
Centers for Disease Control and Prevention
Malaria Alert Centre

Completed

Text Message Reminders to Health Workers on Malaria, Pneumonia, and Diarrhea Case Management in Malawi

Pneumonia | Diarrhea | Malaria
London School of Hygiene and Tropical Medicine
HealthNet TPO; Health Protection and Research Organisation; Medical Emergency...

Completed

Cluster Randomised Trial of Malaria RDTs Used by CHWs in Afghanistan

Pneumonia | Fever | Malaria | Acute Febrile Illness

Afghanistan
University of Oxford
National Health and Medical Research Council, Australia; Burnet Institute; Agency...

Recruiting

Characterizing Humoral Immune Response to Mosquito Bites (SG6)

Malaria | Dengue

Thailand
Bill & Melinda Gates Medical Research Institute

Not yet recruiting

Study To Evaluate Safety, Tolerability, and Pharmacokinetics of MAM01 in African Population

Healthy Volunteers

Kenya, Uganda
Assistance Publique - Hôpitaux de Paris

Unknown

Contrast-Enhanced US of Spleen, Liver and Kidney

Bacterial Infections | Malaria | Pyelonephritis

France
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Role of Nitric Oxide in Malaria

Malaria | Pulmonary Hypertension

Mali
BioMérieux
Institut de Recherche pour le Developpement; Centre National de la Recherche... and other collaborators

Completed

Immune Dysfunction in Newborn Sepsis (RECIPAL)

Malaria | Sepsis Newborn | Immune Responses
Leiden University Medical Center

Withdrawn

Leiden University Medical Center Mini Donor Bank

Diabetes | Asthma | Malaria | Schistosoma Haematobium | Schistosoma Mansoni
University of North Carolina, Chapel Hill

Completed

Impact of Host Iron Status and Iron Supplement Use on Erythrocytic Stage of Plasmodium Falciparum

Malaria | Iron Deficiency Anemia

United States
Centre de Recherche Médicale de Lambaréné

Completed

Effect of Artemisinin-based Combination Therapies on Schistosomiasis on Malaria Co-infection (SACT)

Schistosomiasis Haematobia

Gabon
Columbia University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Malaria and the Safety of Iron Supplements and Iron Fortification (MIA)

Iron Deficiency

Thailand
University of Melbourne
University of Barcelona; Papua New Guinea Institute of Medical Research; The... and other collaborators

Completed

Intermittent Preventive Treatment With Azithromycin-containing Regimens in Pregnant Women in Papua New Guinea (IPTp in PNG)

Sexually Transmitted Infections | Malaria in Pregnancy | Anaemia

Papua New Guinea
Pyae Linn Aung
University of South Florida; Mahidol University

Active, not recruiting

Efficacy of Focal Primaquine Mass Administration for Eliminating Plasmodium Vivax Malaria in Northern Myanmar

Malaria | Plasmodium Vivax | Myanmar | Mass Drug Administration | Primaquine

Myanmar
BioMérieux

Completed

Impact of Differential and Systematic Diagnosis of Dengue, Chikungunya and Malaria on Patient Management and Antibiotic Use in West Africa

Malaria | Dengue | Chikungunya

Burkina Faso, Côte D'Ivoire
National Institute of Environmental Health Sciences...

Completed

Study of DDT and Loss of Clinically-Recognized Pregnancies in South Africa

HIV Infections | Malaria | Pregnancy Outcome | Stillbirth | Spontaneous Abortion

South Africa
Wageningen University
University of California, Davis; Penn State University; University of Ibadan; Newcastle... and other collaborators

Completed

Assessing Model Parameters for Applying the Retinol Isotope Dilution (RID) Method (SUPERKID)

Inflammation | Malaria | Vitamin A Deficiency

Nigeria
Centers for Disease Control and Prevention
Kenya Medical Research Institute

Completed

Impact of Cotrimoxazole Prophylaxis for HIV-Infected Adults on Antifolate Resistance

Pneumonia | Diarrhea | HIV | Malaria | Opportunistic Infections

Kenya
Last Mile Health
Massachusetts General Hospital; Northwestern University; Georgetown University; Heidelberg University

Active, not recruiting

Liberia National Community Health Assistant (NCHA) Program and Under-five Mortality

Diarrhea | Malaria | Acute Respiratory Infection | Malnutrition, Child

Liberia
Harvard School of Public Health (HSPH)
Muhimbili University of Health and Allied Sciences

Completed

Malaria in Pregnancy: Nutrition and Immunologic Effects (MAL2)

Anemia | Low Birth Weight | Malaria | Perinatal Mortality

Tanzania
Makerere University

Completed

Sulfadoxine- Pyrimethamine Versus Weekly Chloroquine for Malaria Prevention in Children With Sickle Cell Anemia

Malaria | Sickle Cell Anemia

Uganda
Karolinska Institutet
European Foundation for the Study of Diabetes; University of Dschang

Recruiting

Diabetes, Metabolic Syndrome and Risk of Malaria in Cameroon

Diabetes Mellitus | Metabolic Syndrome | Malaria | Endemic

Cameroon
DBL -Institute for Health Research and Development

Completed

Assessment of Anaemia Attributable to Schistosomiasis in School Children in Kenya: Mechanisms and Effect of Treatment

Malaria | Iron Deficiency | Anaemia | Schistosomiasis Infection

Kenya
Liverpool School of Tropical Medicine
London School of Hygiene and Tropical Medicine; Bill and Melinda Gates Foundation and other collaborators

Completed

Malaria as a Risk Factor for COVID-19 in Western Kenya and Burkina Faso (MALCOV)

Covid-19 | Malaria

Burkina Faso, Kenya
Institute of Tropical Medicine, Belgium

Terminated

Malaria as a Protection Factor Against Severe COVID-19 (Known as SARS-COV-2) in the Democratic Republic of Congo (Palu-COVID) (Palu-COVID)

Covid19 | Paludism

Congo, The Democratic Republic of the
Indiana University
Children's Hospital Medical Center, Cincinnati; Makerere University; Doris Duke... and other collaborators

Completed

Optimizing Hydroxyurea Therapy in Children With SCA In Malaria Endemic Areas (NOHARM-MTD)

Malaria | Sickle Cell Disease | Sickle Cell Anemia

Uganda
Programme Against Malnutrition
Hitotsubashi University; Alliance Forum Foundation

Completed

Spirulina Supplementation and Infant Growth, Morbidity and Motor Development

Cough | Fever | Malaria | Pneumonia, Pneumocystis | Stunting | Underweight | Motor Delay

Zambia
Indiana University
Children's Hospital Medical Center, Cincinnati; Makerere University; Doris Duke... and other collaborators

Completed

Novel Use Of Hydroxyurea in an African Region With Malaria (NOHARM)

Malaria | Sickle Cell Disease | Sickle Cell Anemia

Uganda
The Mentor Initiative
Liverpool School of Tropical Medicine; University of Maiduguri; US government; ...

Completed

Field Evaluations of Innovative Tools for Vector-borne Disease Control in Conflict-affected Communities

Vector Borne Diseases | Malaria | Childhood ALL

United Kingdom
Liverpool School of Tropical Medicine
University of Bergen; Indiana University; Makerere University; University of Malawi and other collaborators

Completed

Dihydroartemisinin-Piperaquine or Sulphadoxine-Pyrimethamine for the Chemoprevention of Malaria in Sickle Cell Anaemia (CHEMCHA)

Malaria | Sickle Cell Anemia in Children

Uganda, Malawi
Biomedical Research Center EPLS
Institut National de la Santé Et de la Recherche Médicale, France; Institut... and other collaborators

Completed

Study of the Environmental Factors Modulating Children Immune Response in Northern Senegal (AnoPalAnoVac)

Whooping Cough | Malnutrition | Malaria

Senegal

Clinical Trials on Malaria, Falciparum

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