Clinical Trials on Non-Infectious Systemic Inflammatory Response Syndrome

Total 10439 results

Seattle Children's Hospital
Immunexpress

Completed

Gene Expression Objective Definition of Early Sepsis In Children (GEODESIC)

Sepsis | Non-Infectious Systemic Inflammatory Response Syndrome

United States
Arkansas Children's Hospital Research Institute
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Terminated

Goal-directed Resuscitative Interventions During Pediatric Inter-facility Transport (The GRIPIT Trial) (GRIPIT)

SIRS (Systemic Inflammatory Response Syndrome(

United States
Immunexpress
Johns Hopkins University; Northwell Health; Rush University Medical Center; Intermountain... and other collaborators

Completed

VENUS: Septic Gene Expression Using SeptiCyte (VENUS)

Sepsis | Systemic Inflammatory Response Syndrome (SIRS)

United States
Chinese PLA General Hospital

Completed

Detection Of Monocytes/Macrophages Function And Tim-3 Expression In Septic Patients

Sepsis | SIRS(Systemic Inflammatory Response Syndrome)

China
Chinese PLA General Hospital

Unknown

The Changes of CD4+T Lymphocyte Subsets in Septic Patients

Sepsis | SIRS(Systemic Inflammatory Response Syndrome)

China
Seattle Children's Hospital
Immunexpress

Completed

Genotypes and Phenotypes in Pediatric SIRS and Sepsis (GAPPSS)

Sepsis | Systemic Inflammatory Response Syndrome (SIRS)

United States
University Hospital, Limoges

Terminated

Following of Myeloid-derived Suppressor Cells (MDSC) in Severe Sepsis: What Relationship With Systemic Inflammatory Syndrome? (MDSC)

Severe Sepsis | Inflammatory Response Syndrome, Systemic

France
Palle Bekker Jeppesen
TauroPharm

Unknown

Clinical Trial Comparing Catheter Lock Solutions TaurolockTMHep 100 and Heparin 100 IE/ml.

Catheter-related Bloodstream Infection (CRBSI) Nos

Denmark
Wuhan Union Hospital, China

Recruiting

Correlation of Memory CD8+ T Cells With Sepsis Severity and Mortality: a Single-center, Unblinded, Prospective, Non-interventional, Observational Study

Sepsis | Inflammatory Response

China
The University of Queensland
Royal Brisbane and Women's Hospital

Unknown

Exercise in Critically Ill Patients With Sepsis

Sepsis Syndromes

Australia
Wuhan Union Hospital, China

Recruiting

Immunoinflammatory Regulation of Esketamine in Septic Patients

Sepsis | Inflammatory Response | Immunosuppression | Esketamine

China
Radboud University Medical Center
Exponential Biotherapies Inc.

Completed

PK/PD of EA-230 During Endotoxemia

Endotoxemia | Systemic Inflammatory Response

Netherlands
Abbott Diagnostics Division

Completed

Procurement of Human Specimens for the Evaluation of Early Markers of Sepsis (EMOS)

Infection

United States
Federal University of Minas Gerais
Fundação de Amparo à Pesquisa do estado de Minas Gerais

Completed

Duration of Antibiotic Therapy in Critically Ill Patients: C-reactive Protein-guided Therapy Versus Best Practice

Infection Systemic

Brazil
Cytovale, Inc.

Active, not recruiting

CV-SQuISH-ED: Clinical Validation Study

Sepsis | Infection

United States
St. Jude Children's Research Hospital
Karius, Inc.

Active, not recruiting

Next Generation Pathogen Sequencing for Prediction of Adverse Events

Bloodstream Infection

United States
Fundación Grupo de Investigación en Cuidados Intensivos...

Completed

Validation of the Quick Sequential [Sepsis-related] Organ Failure Assessment (qSOFA) in Obstetric Patients (COLOSSAL)

Severe Infection

Colombia
Phillip Brian Smith

Completed

Pharmacokinetics (PK) of Antistaphylococcal Antibiotics in Infants (NICHD-2012-02-Staph Trio) (Staph)

Systemic Infection

United States
The University of Queensland
Shionogi

Completed

RCT Cefiderocol vs BAT for Treatment of Gram Negative BSI (GAMECHANGER)

Bloodstream Infections

Taiwan, Thailand, Singapore, Australia, Malaysia, Turkey
Federal University of Minas Gerais
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Recruiting

Efficacy and Safety of a Protocol Using C-reactive Protein to Guide Antibiotic Therapy

Systemic Infection

Brazil
William Osler Health System
Angiodynamics, Inc.

Completed

Access in Dialysis for Better Outcomes in Patient Therapy (ADOPT)

Central Venous Catheter | Catheter-Related Bloodstream Infection (CRBSI) Nos

Canada
The University of Queensland

Completed

Trial of Meropenem Versus Piperacillin-Tazobactam on Mortality and Clinial Response (MERINO II)

Bloodstream Infections

Singapore, Australia
The First People's Hospital of Huzhou

Completed

Clinical Analysis of Vitamin B6 in Sepsis

Sepsis | Inflammatory Response | Kidney Injury | Vitamin B6 | Oxidative Stress Response

China
University Hospital, Basel, Switzerland

Completed

Clinical Impact of Rapid Identification of Positive Blood Cultures vs. Internal Laboratory Standard

Bloodstream Infections

Switzerland
Hellenic Institute for the Study of Sepsis
Aristotle University Of Thessaloniki; National and Kapodistrian University...

Completed

Heparin Binding Protein in Early Sepsis Diagnosis (PROMPT)

Sepsis | Infection

Greece
University of British Columbia
Kenya Medical Research Institute

Completed

Paediatric Rapid Sepsis Trigger (PRST) Tool (PRST)

Sepsis | Infection

Uganda, Kenya
University Hospital Ostrava
Public Health Institute Ostrava

Completed

Presepsin in the Diagnosis of Sepsis in Critically Ill Patients

Sepsis | Infection

Czechia
Accelerate Diagnostics, Inc.

Active, not recruiting

Genotypic Versus Phenotypic Susceptibility Testing of Positive Blood Cultures

Bloodstream Infection

United States
Immunexpress
Rhode Island Hospital

Terminated

The Ward Study for SeptiCyte® Lab to Distinguish Between Infection-positive and Infection-negative SIRS

Sepsis | SIRS

United States
University of Tennessee

Unknown

Electronic Application of a Severe Sepsis Screening Tool and Management Bundle (eASSIST-M)

Sepsis | Septic Shock | Severe Sepsis | Systemic Inflammatory Response Syndrome (SIRS)

United States
Tufts Medical Center
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Salivary Profiling in Infants Treated for Suspected Sepsis: The SPITSS Study (SPITSS)

Infection; Newborn

United States
Children's Cancer and Leukaemia Group

Unknown

Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter

Infection

United Kingdom, Ireland
University of Cologne

Completed

Systemic Inflammatory Response Syndrome (SIRS) in Patients Undergoing Major Procedures in Oral and Maxillofacial Surgery

Systemic Inflammatory Response Syndrome (SIRS)

Germany
Pfizer
Forest Laboratories

Completed

Safety and Tolerability of Ceftazidime-Avibactam for Pediatric Patients With Suspected or Confirmed Infections

Systemic Infections

United States
The University of Queensland
Australasian Society for Infectious Diseases; International Society of Chemotherapy and other collaborators

Terminated

RCT Meropenem vs Piperacillin-Tazobactam for Definitive Treatment of BSI's Due to Ceftriaxone Non-susceptible Escherichia Coli and Klebsiella Spp. (MERINO)

Bloodstream Infections

Australia, Singapore, South Africa, Italy, Saudi Arabia, Canada, Lebanon, New Zealand, Turkey
Beckman Coulter, Inc.

Completed

Evaluation of Monocyte Volume Distribution Width (MDW) for Early Detection of Sepsis (MDW)

Sepsis | Severe Infection

United States
International Centre for Diarrhoeal Disease Research...
Centers for Disease Control and Prevention; State University of New York at...

Completed

Perinatal Handwashing Intervention in Bangladesh

Sepsis | Infection | Umbilical Cord

Bangladesh
Charite University, Berlin, Germany
Sysmex Europe GmbH

Completed

Hematological Infection Score Compared to the Hospital Standard for Diagnosis of SIRS or Sepsis on ICU

Sepsis | SIRS

Germany
Tianjin Medical University Cancer Institute and...
Zhejiang Hisun Pharmaceutical Co. Ltd.

Unknown

Effect Study of Tigecycline to Treat Severe Sepsis and Septic Shock (Tigecycline)

Abdominal Infection

China
Rigshospitalet, Denmark

Completed

Catheter Salvage in Intestinal Failure Patients

Intestinal Failure | Catheter-Related Bloodstream Infection (CRBSI) Nos

Denmark
Baylor College of Medicine

Completed

Catheter Biofilm Microbiome in Infected Neonatal Catheters.

Catheter-associated Bloodstream Infections (CLABSI)

United States
Beckman Coulter, Inc.
Saint-Louis Hospital, Paris, France; Hôpital Raymond Poincaré

Completed

Leukocyte MOrphology and CORticosteroids Response in SEPtic Patients (MOCORSEP) (MOCORSEP)

Sepsis | Septic Shock | Infection | Sepsis Syndrome

France
Medical University of Gdansk

Completed

Bands in Peripheral Blood After Coronary Artery Bypass Grafting With and Without Cardiopulmonary Bypass

Inflammatory Response Syndrome, Systemic | Granulocyte Immature Forms

Poland
Jongmin Lee

Completed

Presepsin as Detective Marker of Sepsis in Immunodeficiency ICU Patients (PREICU)

Sepsis | Immune Deficiency

Korea, Republic of
Chang Gung Memorial Hospital

Unknown

Application of Stimulated Immune Response Change to Predict Outcome of Patient With Severe Sepsis (SIRCSS)

Sepsis | Septic Shock | Severe Sepsis | Multiple Organ Failure | Systemic Inflammatory Response Syndrome (SIRS)

Taiwan
University Hospital of Canary Islands

Completed

Adding Vortexing to the Maki Technique Provides no Benefit for the Diagnosis of Catheter-related Bacteremia

Catheter-related Bloodstream Infection

Spain
Assiut University

Unknown

Prognostic Value of Complete Blood Count in Severe Infections

Infection Systemic
BioFire Diagnostics, LLC

Unknown

Pilot Evaluation of the FilmArray® Childhood Systemic Infection (CSI) Panel

Systemic Infection

United States
Children's Healthcare of Atlanta

Terminated

Chlorhexidine Swabs Effectiveness in Reducing Blood Stream Infections

Congenital Disorders

United States
Chang Gung Memorial Hospital

Unknown

Application of Biomarkers Change to Predict Outcome of Patient With Severe Sepsis (BCSS)

Sepsis | Septic Shock | Severe Sepsis | Multiple Organ Failure | Systemic Inflammatory Response Syndrome (SIRS)

Taiwan

Clinical Trials on Non-Infectious Systemic Inflammatory Response Syndrome

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