Clinical Trials on Patients With Severe Chronic Pain in United States

Total 2475 results

Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN) (HR-NBL2)

High-Risk Neuroblastoma | Patient With Insufficient Response Chemoimmunotherapy

France, Germany, Israel, Spain, United Kingdom, Belgium, Norway, Sweden, Finland, Australia, Czechia, Italy, Netherlands, Slovenia, Switzerland, Denmark, Greece, Lithuania, Slovakia
Duke University
United States Department of Defense

Completed

Neuromodulatory Treatments for Pain Management in TBI

Chronic Pain | Traumatic Brain Injury | Posttraumatic Stress Disorder

United States
Kenneth B Chapman
Abbott

Recruiting

Dorsal Root Ganglion Stimulation for the Treatment of Arthritic Knee Pain

Knee Osteoarthritis | Knee Arthritis | Knee Arthropathy | Knee Pain Chronic

United States
Bausch Health Americas, Inc.

Completed

Mesalamine Granules for Irritable Bowel Syndrome (IBS) With Diarrhea

Irritable Bowel Syndrome With Diarrhea

United States
Eli Lilly and Company

Completed

A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Diabetic Peripheral Neuropathic Pain (NP05)

Chronic Pain | Diabetic Peripheral Neuropathic Pain | Diabetic Peripheral Neuropathy

United States, Puerto Rico
Hospital General de Mexico

Completed

Lactobacillus LB as Treatment for Irritable Bowel Syndrome With Predominance of Diarrhea (IBS-D)

Irritable Bowel Syndrome With Diarrhea

Mexico
Dana-Farber Cancer Institute
National Cancer Institute (NCI); Pharmavite LLC

Recruiting

Vitamin D in Patients With Stage I-III Colon Cancer or Resectable Colon Cancer Liver Metastases

Stage, Colon Cancer | Stage I-III Colon Cancer | Stage IV Colon Cancer With Resectable Liver Metastases

United States
Guy's and St Thomas' NHS Foundation Trust
King's College London

Unknown

Direct Access to MRI and Neurology Referrals for the Management of Patients With Chronic Headache.

Chronic Headache

United Kingdom
Takeda

Terminated

Effect of Febuxostat Compared to Placebo on Exercise Tolerance in Participants With Chronic Stable Angina

Angina

United States
Craig Hospital
Mayo Clinic; University of Alabama at Birmingham; Wayne State University; NYU Langone... and other collaborators

Completed

Characterization & Treatment of Chronic Pain After Moderate to Severe TBI

Pain | Traumatic Brain Injury

United States
Bioness Inc

Recruiting

StimRouter Registry Clinical Protocol

Nervous System Diseases | Chronic Pain | Peripheral Nervous System Diseases | Peripheral Neuropathy | Peripheral Nerve Injuries | Peripheral Nervous System Problem | Peripheral Nervous

United States
King's College Hospital NHS Trust
Samsung Medison

Recruiting

Effectiveness of Ultrasound in Liver Stiffness and Fat Quantification

Hepatitis | Liver Fat | NAFLD | Fibrosis, Liver | Liver Disease Chronic | Liver Steatoses | NASH With Fibrosis

United Kingdom
University of Arizona

Terminated

Whole Body Hyperthermia Registry Study

Depression | PTSD | Fibromyalgia | Anxiety | Chronic Fatigue Syndrome

United States
Cardiovascular Consultants of Nevada
Gilead Sciences

Unknown

Safety of Amiodarone and Ranolazine Together in Patients With Angina (SARA)

Coronary Artery Disease | Atrial Fibrillation | Ventricular Tachycardia | Chronic Stable Angina

United States
Masonic Cancer Center, University of Minnesota

Terminated

Monitoring of Immune and Microbial Reconstitution in (HCT) and Novel Immunotherapies

Cytokine Release Syndrome | Immune and Microbial Reconstitution | Systemic Viral Infection | Acute-graft-versus-host Disease | Chronic Graft-versus-host-disease | Recurrent Malignancy | Allogenic Related Donors | Cell Therapy/Immunotherapy Patients

United States
Suzhou Connect Biopharmaceuticals, Ltd.

Completed

A Study Assessing the Efficacy and Safety of CBP-307 in Subjects With Moderate to Severe Ulcerative Colitis (UC)

Moderate to Severe Ulcerative Colitis

United States, China, Pakistan, Ukraine
University of Washington
Department of Health and Human Services

Recruiting

Telehealth Pain Self-Management for Employed Adults (E-TIPS)

Multiple Sclerosis | Chronic Pain | Brain Injuries, Traumatic | Amputation | Spinal Cord Injuries

United States
Aberdeen Royal Infirmary

Unknown

Chronic Pain in Women Who Have Undergone Surgery for Stage I, Stage II, or Stage III Breast Cancer

Pain | Breast Cancer | Perioperative/Postoperative Complications

United Kingdom
Mesoblast International Sàrl

No longer available

Intermediate-size Expanded Access Program (EAP), Mesenchymal Stromal Cells (MSC) for Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19 Infection

Moderate to Severe Acute Respiratory Distress Syndrome Associated With COVID-19

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

WEE1 Inhibitor AZD1775 With or Without Cytarabine in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome

Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Myelodysplastic/Myeloproliferative Neoplasm | Myelodysplastic Syndrome With Isolated Del(5q)

United States
Jennifer Moreno Clinic

Unknown

Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy

Knee Osteoarthritis | Muscle Weakness | Muscle Weakness Condition | Knee Arthritis | Knee Pain Chronic | Knee Pain Swelling | Knee Deformity | Power

United States
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without PSC 833, Peripheral Stem Cell Transplantation, and/or Interleukin-2 in Treating Patients With Acute Myeloid Leukemia

Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute Myeloblastic Leukemia Without Maturation... and other conditions

United States
Mid and South Essex NHS Foundation Trust
Imperial College London

Recruiting

A Placebo-controlled Trial of Chronic Total Occlusion Percutaneous Coronary Intervention for the Relief of Stable Angina (ORBITA-CTO)

Stable Angina | Chronic Total Occlusion of Coronary Artery

United Kingdom
Brigham and Women's Hospital
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Active, not recruiting

Vitamin D and Fish Oil for Autoimmune Disease, Inflammation and Knee Pain (VITAL)

Autoimmune Diseases | Osteoarthritis | Rheumatoid Arthritis | Knee Pain Chronic | Systemic Inflammatory Process

United States
Catherine Bollard

Active, not recruiting

Cytotoxic T Cells to Treat Relapsed EBV-positive Lymphoma (ALCI2)

Hodgkin Disease | Non Hodgkin Lymphoma | Leiomyosarcoma | Lymphoepithelioma | Severe Chronic Active EBV Infection Syndrome (SCAEBV)

United States
Sheffield Teaching Hospitals NHS Foundation Trust
Schering-Plough

Completed

Testosterone Therapy on Angina Threshold and Atheroma in Patients With Chronic Stable Angina

Angina Pectoris

United Kingdom
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

TTI-622 and TTI-621 in Combination With Pembrolizumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Recurrent Diffuse Large B-Cell... and other conditions

United States
OSF Healthcare System

Enrolling by invitation

Analysis of the Virtual Acute Care at Home Experience (HaH)

Heart Failure | Infections | Hypertension | Diabetes | Fever | Bronchitis | Asthma, Chronic Obstructive Pulmonary Disease (COPD) | Conditions | Renal and Urinary Disorders

United States
University of Washington
University of California, San Francisco

Completed

Biofeedback-VR for Treatment of Chronic Migraine

Medication Overuse Headache | Virtual Reality | Chronic Migraine | Biofeedback | Behavioral Treatment

United States
Nina Bhardwaj
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes... and other collaborators

Completed

Enhancement by Poly-ICLC During HIV-1 Infection (Poly-ICLC)

HIV-1 Infected Adults With Chronic HIV-1 Infection

United States
Axogen Corporation

Completed

Study of AxoGuard® Nerve Cap and Neurectomy for Treatment of Symptomatic Neuroma & Prevention of Recurrent Neuroma Pain (REPOSE)

Symptomatic Neuroma | Chronic Nerve Pain | Morton's Neuroma

United States
Scripps Health

Completed

Unrelated Donor Stem Cell Transplantation

Myelodysplastic Syndromes | Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Small Lymphocytic Lymphoma | Paroxysmal Nocturnal Hemoglobinuria | Severe Aplastic Anemia | Myeloproliferative... and other conditions

United States
University of California, San Diego
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Managing Opioid Related Sleep Apnea With Acetazolamide (MORPHO)

Chronic Pain | Obstructive Sleep Apnea | Opioid Use | Sleep-Disordered Breathing | Central Sleep Apnea

United States
University of Michigan
National Institute of Nursing Research (NINR); Detroit Department of Health

Recruiting

A Trial of a Positive Psychology Intervention for Older Adults (RESET) During the COVID-19 Pandemic

Fatigue | Chronic Pain | Stress, Psychological | Anxiety | Depressive Symptoms | Loneliness

United States
VA Office of Research and Development

Completed

The Impact of Modifiable Psychosocial Factors on Veterans' Long-term Trajectories of Functioning and Quality of Life: Promoting Recovery by Targeting Mindfulness and Psychological Flexibility (SERVE: IMPACT)

Depression | PTSD | Chronic Pain | Traumatic Brain Injury | Alcohol Use Disorder

United States
Oregon Health and Science University
University of Arizona

Completed

Clinical Trial Examining Effects of Monosodium Glutamate (MSG) on Irritable Bowel Syndrome (IBS) and Fibromyalgia (FM)

Irritable Bowel Syndrome | Fibromyalgia

United States
Texas Heart Institute
POM Wonderful LLC

Completed

Pomegranate Products for Prevention of Common Cold

Cough | Fever | Influenza | Headache | Common Cold

United States
National Cancer Institute (NCI)

Completed

Sorafenib in Treating Patients With Refractory or Relapsed Acute Leukemia, Myelodysplastic Syndromes, or Blastic Phase Chronic Myelogenous Leukemia

Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Recurrent Adult Acute Lymphoblastic Leukemia | Secondary Myelodysplastic Syndrome | de Novo Myelodysplastic Syndrome | Adult Acute Monoblastic Leukemia | Adult Acute Monocytic... and other conditions

United States
Otsuka Pharmaceutical Development & Commercialization...

Completed

Efficacy, Safety and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

Agitation in Patients With Dementia of the Alzheimer's Type

United States, Estonia, Germany, Poland, Portugal, Puerto Rico
University of Colorado, Boulder

Completed

Denver Garden Environment and Microbiome Study Disease (DGEM)

Physical Activity | Chronic Disease | Diet Modification | Weight Gain | Health Behavior | Lifestyle, Sedentary

United States
Axsome Therapeutics, Inc.

Enrolling by invitation

A Study to Assess the Long-term Safety and Efficacy of AXS-05 in Subjects With Alzheimer's Disease Agitation

Alzheimer Disease | Agitation in Patients With Dementia of the Alzheimer's Type | Agitation, Psychomotor

United States, Canada
University College, London
University College London Hospitals

Completed

Oral Epithelial Dysplasia Informational Needs Questionnaire (ODIN-Q)

Quality of Life | Precancerous Conditions | Patient Engagement | Patient Participation | Oral Disease | Patient Satisfaction | Health Behavior | Precancerous Lesions | Oral Leukoplakia | Dental Diseases | Oral Lichen Planus | Dysplasia | Patient Preference | Information Seeking Behavior | Oral Epithelial Dysplasia | Oral... and other conditions

United Kingdom
Hoffmann-La Roche
Pfizer

Completed

A Study to Evaluate the Efficacy and Safety of PF-06480605 in Adults With Moderate to Severe Ulcerative Colitis

Moderate to Severe Ulcerative Colitis

United States, Australia, Thailand, Poland, Russian Federation, Japan, Colombia, Spain, Turkey, Romania, India, Slovakia, France, Hungary, South Africa, Belgium, Bulgaria, Germany, Italy, Mexico, Serbia, Ukraine, United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Ex Vivo-activated Autologous Lymph Node Lymphocytes in Treating Patients With Chronic Lymphocytic Leukemia

Anemia | Weight Loss | Thrombocytopenia | Fever | Chronic Lymphocytic Leukemia | Lymphadenopathy | Prolymphocytic Leukemia | Richter Syndrome | Cancer Fatigue | Recurrent Chronic Lymphocytic Leukemia | Lymphocytosis | Infectious Disorder | Night Sweats | Secondary Malignant Neoplasm

United States
Mayo Clinic

Not yet recruiting

A Study of the Effect of a Nurse Navigator Program on High Risk Patients

Heart Failure | Alcoholism | Renal Insufficiency | Pulmonary Disease, Chronic Obstructive | Arthroplasty, Replacement, Knee | Arthroplasty, Replacement, Hip | Body Mass Index | Patient Readmission

United States
University of California, San Francisco

Completed

Phase II Study Evaluating Busulfan and Fludarabine as Preparative Therapy in Adults With Hematopoietic Disorders Undergoing MUD SCT

Multiple Myeloma | Non-Hodgkin's Lymphoma | Chronic Myeloid Leukemia | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Myelodysplasia | Severe Aplastic Anemia | Lymphoproliferative Disease | Advanced Myeloproliferative Disease

United States
Duke University
National Center for Complementary and Integrative Health (NCCIH)

Completed

Pain Management Using Mobile Technology in Veterans With PTSD and TBI

Chronic Pain | Posttraumatic Stress Disorders | Traumatic Brain Injury

United States
Novartis Pharmaceuticals

Terminated

Safety and Efficacy Study of SOM230 s.c. in Cluster Headache

Cluster Headache - Episodic and Chronic

United States, United Kingdom, Germany
Roswell Park Cancer Institute

Completed

Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Primary Myelofibrosis | Polycythemia Vera | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma and other conditions

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Stage III Community-based Efficacy Trial for Mothering From the Inside Out

Child Abuse | Parent-Child Relations | Parenting | Parents | Addiction | Child Neglect | Substance Abuse Drug Chronic | Child Neglect Emotional | Parent-Child Problem | Parent / Child Problem | Parenteral Drug Abuse

United States

Clinical Trials on Patients With Severe Chronic Pain in United States

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Kyrgyzstan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

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