Clinical Trials on Pleural Effusion in South Africa

Total 72 results

Clover Biopharmaceuticals AUS Pty Ltd

Completed

Study With SCB-313 (Recombinant Human TRAIL-Trimer Fusion Protein) for Treatment of Malignant Pleural Effusions

Malignant Pleural Effusions

Australia
BioSyngen Pte Ltd

Unknown

A Study of Syngenon (BSG-001) for Inhalation in Subjects With Malignant Pleural Effusion and/or Malignant Ascites

Malignant Ascites | Malignant Pleural Effusion

Australia
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; Radiation... and other collaborators

Completed

Talc in Treating Patients With Malignant Pleural Effusion

Metastatic Cancer

United States, Canada
Philips Clinical & Medical Affairs Global

Completed

Point of Care Ultrasound Lung Artificial Intelligence (AI) Validation Data Collection Study (AI)

Pleural Effusion | Lung Consolidation

United States
Johns Hopkins University
Medical University of South Carolina; Vanderbilt University Medical Center; University... and other collaborators

Recruiting

Gravity Versus Vacuum Based Indwelling Tunneled Pleural Drainage System (NEWTON)

Pleural Effusion

United States, United Kingdom
National Cancer Institute (NCI)

Completed

Erlotinib Hydrochloride With or Without Carboplatin and Paclitaxel in Treating Patients With Stage III-IV Non-small Cell Lung Cancer

Lung Adenocarcinoma | Minimally Invasive Lung Adenocarcinoma | Malignant Pleural Effusion | Stage IIIB Lung Non-Small Cell Cancer AJCC v7 | Stage IV Lung Non-Small Cell Cancer AJCC v7 | Malignant Pericardial Effusion | Lung Adenosquamous Carcinoma

United States
University of Cape Town
Population Health Research Institute; Walter Sisulu University

Unknown

IMPI 2 - A Trial of Intrapericardial Alteplase in Large Pericardial Effusion (IMPI-2)

Pericardial Effusion

South Africa
Chung Shan Medical University
Ministry of Education, Taiwan

Completed

Enhancing Respiratory Auscultation Skills Among Medical Students: Digital Stethoscopes in Medical Education

Pneumonia | Asthma | Pleural Effusion | Breathing Sound | Auscultation

Taiwan
Novartis Pharmaceuticals

Completed

Non-small Cell Lung Cancer Registry

Pleural Effusion, Malignant | Non-Small-Cell Lung Cancer

United States
University of Cape Town

Completed

VATS ( Video-Assisted Thoracoscopy) Compared to Reinsertion of a Thoracostomy Tube for Persistent Haemothorax

Empyema | Haemothorax

South Africa
Otonomy, Inc.

Completed

Open-Label Study of OTO-201 for Middle Ear Effusion Evaluating Trans-Tympanostomy Tube Administration

Bilateral Middle Ear Effusion

United States
Tusker Medical

Completed

Adult Study to Evaluate Placement of Tympanostomy Tubes In-office (ADEPT) (ADEPT)

AOM - Acute Otitis Media | Eustachian Tube Dysfunction | Barotrauma;Ear | OME - Otitis Media With Effusion

United States
Tusker Medical

Completed

In-Office Tympanostomy Tube Placement in Children (OTTER) (OTTER)

AOM - Acute Otitis Media | OME - Otitis Media With Effusion

United States, Canada
University of Bern
University of Alabama at Birmingham; University of Southern California; Louisiana... and other collaborators

Active, not recruiting

Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa

HIV Infections | Premature Birth | Microbial Colonization | Pregnancy; Infection | Bacterial Vaginosis | Trichomonas Vaginitis | Neisseria Gonorrheae Infection | Chlamydia Trachomatis Infection | Mycoplasma Genitalium Infection | Genital Mycoplasma Infection | Vaginal Candida | Sexually Transmitted Infections... and other conditions

South Africa
Medical University of South Carolina
Guerbet

Recruiting

Dotarem Evaluation for Myocardial Perfusion CMR

Magnetic Resonance Imaging | Myocardial Perfusion Imaging

United States
Wales Cancer Trials Unit
Velindre NHS Trust; June Hancock Mesothelioma Research Fund; Velindre Cancer...

Unknown

A Phase II Trial to Assess TroVax® Plus Chemotherapy in Patients With Malignant Pleural Mesothelioma (SKOPOS)

Mesothelioma | Malignant | Pleural

United Kingdom
SCRI Development Innovations, LLC
Amgen

Completed

A Retrospective Cohort Study of Infusion Reactions Due to Vectibix

Infusion Reaction

United States
Virttu Biologics Limited

Completed

Intrapleural Administration of HSV1716 to Treat Patients With Malignant Pleural Mesothelioma. (1716-12)

Malignant Pleural Mesothelioma

United Kingdom
PrECOG, LLC.
AstraZeneca; University of Sydney; Thoracic Oncology Group Australasia (TOGA)

Active, not recruiting

DuRvalumab With chEmotherapy as First Line treAtment in Advanced Pleural Mesothelioma (DREAM3R)

Mesothelioma | Malignant Pleural Mesothelioma | Pleural Mesothelioma

United States, Australia, New Zealand
National Cancer Institute (NCI)

Terminated

Tivantinib in Treating Patients With Previously Treated Malignant Mesothelioma

Epithelioid Mesothelioma | Sarcomatoid Mesothelioma | Stage IV Pleural Mesothelioma | Recurrent Malignant Mesothelioma | Stage II Pleural Mesothelioma | Stage III Pleural Mesothelioma

United States
Asbestos Diseases Research Foundation
EnGeneIC Limited

Completed

MesomiR 1: A Phase I Study of TargomiRs as 2nd or 3rd Line Treatment for Patients With Recurrent MPM and NSCLC

Non-Small Cell Lung Cancer | Malignant Pleural Mesothelioma

Australia
European Organisation for Research and Treatment...

Active, not recruiting

Nintedanib as Switch Maintenance Treatment of Pleural Malignant Mesothelioma (NEMO)

Malignant Pleural Mesothelioma

United Kingdom, Belgium, Italy
National Cancer Institute (NCI)

Active, not recruiting

Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma

Biphasic Mesothelioma | Epithelioid Mesothelioma | Stage III Pleural Malignant Mesothelioma AJCC v7 | Stage I Pleural Malignant Mesothelioma AJCC v7 | Stage IA Pleural Malignant Mesothelioma AJCC v7 | Stage IB Pleural Malignant Mesothelioma AJCC v7 | Stage II Pleural Malignant Mesothelioma AJCC...

United States
Arthrex, Inc.

Recruiting

Evaluate the Continued Safety and Performance of the Foot and Ankle Products

Hyperpronated Foot | Reconstruction Surgeries of the Foot | Fixation of Fractures and Fusion (Bunionectomy Osteotomies) of the Foot/Ankle | Fixation of Small Bone Fragments of the Foot/Ankle | Lisfranc Arthrodesis | Mono or Bi-cortical Osteotomies in the Forefoot | First Metatarsophalangeal Arthrodesis and other conditions

Germany, United States, South Africa
New York Blood Center

Recruiting

Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

Infusion Reactions

United States
Verastem, Inc.

Terminated

Placebo Controlled Study of VS-6063 in Subjects With Malignant Pleural Mesothelioma (COMMAND)

Malignant Pleural Mesothelioma

United States, Belgium, United Kingdom, Sweden, Italy, Netherlands, France, Japan, Australia, Canada, New Zealand, Norway, Poland, South Africa, Spain
Morphotek

Terminated

Study of the Safety and Efficacy of Amatuximab in Combination With Pemetrexed and Cisplatin in Subjects With Unresectable Malignant Pleural Mesothelioma (MPM) (ARTEMIS)

Mesothelioma, Malignant

France, United Kingdom, United States, Germany, Australia, Italy
MedImmune LLC

Active, not recruiting

Randomized, Double-blind Study Comparing Tremelimumab to Placebo in Subjects With Unresectable Malignant Mesothelioma (Tremelimumab)

Unresectable Pleural or Peritoneal Malignant Mesothelioma

United States, Italy, Spain, United Kingdom, Belgium, Canada, Poland, France, Korea, Republic of, Hungary, Russian Federation, Germany, Australia, South Africa, Netherlands, Romania, Sweden, Israel, Denmark
AstraZeneca

Recruiting

MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural Mesothelioma (eVOLVE-Meso)

Unresectable Pleural Mesothelioma

Denmark, Italy, Australia, Korea, Republic of, Belgium, United States, Canada, Japan, United Kingdom, China, Brazil, France, Taiwan, Spain, Norway, Switzerland, Turkey, Poland, Germany, South Africa, Netherlands
Trizell Ltd
University of Pennsylvania

Active, not recruiting

Efficacy & Safety of rAd-IFN Administered With Celecoxib & Gemcitabine in Patients With Malignant Pleural Mesothelioma (INFINITE)

Malignant Pleural Mesothelioma

France, United States, Australia, Germany, United Kingdom, Russian Federation, Canada, Italy, Poland
Surgalign Spine Technologies

Unknown

Evolusion Study Using the Zyga SImmetry Sacroiliac Joint Fusion System

Sacroiliac Joint Dysfunction

United States
Bayer

Completed

A Study to Test the Safety of the Investigational Drug Selitrectinib in Children and Adults That May Treat Cancer

Solid Tumors Harboring NTRK Fusion

United States, Belgium, Italy, Germany, Australia, Spain, Singapore, Denmark, France, Ireland
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Sheffield Hallam University

Not yet recruiting

Exercise to Boost Immunity in Advanced Cancer (BICEP)

Pancreatic Cancer | Mesothelioma; Lung

United Kingdom
Merus N.V.

Recruiting

A Study of Zenocutuzumab (MCLA-128) in Patients With Solid Tumors Harboring an NRG1 Fusion (eNRGy)

NSCLC Harboring NRG1 Fusion | Solid Tumours Harboring NRG1 Fusion | Pancreatic Cancer Harboring NRG1 Fusion | NRG1 Fusion

Spain, France, Israel, Belgium, Denmark, United States, Korea, Republic of, Japan, Germany, Netherlands, Austria, Canada, Italy, Norway, Singapore, Sweden, Taiwan, United Kingdom
National Cancer Institute (NCI)

Completed

SU5416 in Treating Patients With Malignant Mesothelioma

Malignant Mesothelioma

United States
Boehringer Ingelheim

Terminated

Nintedanib (BIBF 1120) in Mesothelioma

Mesothelioma

United States, Spain, Canada, United Kingdom, Belgium, Czechia, Sweden, Australia, Germany, Italy, Japan, Russian Federation, Israel, Poland, France, Netherlands, Austria, Mexico, Portugal, Egypt, Argentina, Croatia, Chile, Denmark, Norway and more
Bayer

Recruiting

Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body (ON-TRK)

Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion

United States, Austria, Denmark, Germany, Italy, Norway, Spain, United Kingdom, Brazil, Russian Federation, Switzerland, Taiwan, Canada, China, Australia, Greece, Belgium, Sweden, Korea, Republic of, France, Argentina, Finland, Ireland and more
Bayer

Active, not recruiting

A Study to Test the Safety and Efficacy of the Drug Larotrectinib for the Treatment of Tumors With NTRK-fusion in Children (SCOUT)

Solid Tumors Harboring NTRK Fusion

United States, China, Poland, Australia, Germany, Japan, Canada, Italy, Czechia, Spain, Turkey, United Kingdom, Sweden, Netherlands, France, Switzerland, Korea, Republic of, Denmark, Ireland, Israel, Ukraine
National Cancer Institute (NCI)

Active, not recruiting

Pemetrexed Disodium and Cisplatin With or Without Cediranib Maleate in Treating Patients With Malignant Pleural Mesothelioma

Epithelioid Mesothelioma | Pleural Malignant Mesothelioma | Sarcomatoid Mesothelioma | Recurrent Malignant Mesothelioma

United States
Multitude Therapeutics Inc.
Tigermed Consulting Co., Ltd

Recruiting

AMT-151 in Patients With Selected Advanced Solid Tumours

Ovarian Cancer | Ovarian Epithelial Cancer | Lung Adenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Triple Negative Breast Cancer | Advanced Solid Tumor | Endometrial Cancer | Advanced Cancer | Ovarian Clear Cell Carcinoma | Pancreatic Ductal Adenocarcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial... and other conditions

China, Australia
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Gemcitabine and Epirubicin in Treating Patients With Malignant Mesothelioma

Malignant Mesothelioma

United States
Polaris Group

Completed

Ph 2/3 Study in Subjects With MPM to Assess ADI-PEG 20 With Pemetrexed and Cisplatin (ATOMIC)

Mesothelioma

United States, United Kingdom, Taiwan, Australia, Italy
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Dasatinib in Treating Patients With Previously Treated Malignant Mesothelioma

Malignant Mesothelioma

United States
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd

Completed

Study of Nivolumab Combined With Ipilimumab Versus Pemetrexed and Cisplatin or Carboplatin as First Line Therapy in Unresectable Pleural Mesothelioma Patients (CheckMate743)

Mesothelioma

Brazil, United States, China, Italy, Australia, Belgium, Chile, Colombia, France, Germany, Greece, Japan, Mexico, Netherlands, Poland, Romania, Russian Federation, South Africa, Switzerland, Turkey, United Kingdom
Portsmouth Hospitals NHS Trust
British Lung Foundation; University of Oxford

Completed

Malignant Mesothelioma - Can we Improve Quality of Life (RESPECT-Meso)

Mesothelioma, Malignant

United Kingdom, Australia
Alfacell

Unknown

ONCONASE Plus Doxorubicin Versus Doxorubicin Alone For Patients With Malignant Pleural or Peritoneal Mesothelioma Who Have Had No More Than One Prior Chemotherapy Regimen

Malignant Mesothelioma

United States, Poland, Italy, Germany
SI-BONE, Inc.

Recruiting

Sacral Fracture Fusion/Fixation for Rapid Rehabilitation (SAFFRON)

Osteoporosis | Fragility Fracture | Insufficiency Fractures | Sacral Fracture | Sacroiliac; Fusion | Fracture;Pelvis

United States
MedtronicNeuro

Completed

Implantable Systems Performance Registry (ISPR)

Deep Brain Stimulation | Spinal Cord Stimulation | Sacral Neuromodulation | Drug Infusion (Implantable Pumps)

United States, France, Spain, Germany, United Kingdom, Italy, Austria
Bayer

Completed

Efficacy and Safety Study for an Oral Contraceptive Containing Folate

Contraception | Neural Tube Defects | Oral Contraceptives (OC)

United States
National Cancer Institute (NCI)

Recruiting

Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma

Peritoneal Malignant Mesothelioma

United States

Clinical Trials on Pleural Effusion in South Africa

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