Clinical Trials on Síndrome de Leigh

Total 33889 results

Icahn School of Medicine at Mount Sinai
National Institute on Deafness and Other Communication Disorders (NIDCD)

Completed

Treatments of Mal de Debarquement Syndrome (MdDS) by Habituation of Velocity Storage

Mal de Debarquement Syndrome (MdDS)

United States
Icahn School of Medicine at Mount Sinai
New York University; National Institute on Deafness and Other Communication... and other collaborators

Recruiting

DevRobust Treatment for Mal de Débarquement Syndrome

Mal de Débarquement Syndrome

United States
Riphah International University

Recruiting

Mobilization With Movement Versus Soft Tissue Mobilization in Patients With De Quervain Tenosynovitis

De Quervain Syndrome

Pakistan
Horizon Pharma USA, Inc.

Completed

Open-Label, Dose-Escalating Study Assessing Safety, Tolerability, Efficacy, of RP103 in Mitochondrial Disease (MITO-001)

Inherited Mitochondrial Disease, Including Leigh Syndrome

United States
PTC Therapeutics
Axio Research. LLC

Completed

Safety and Efficacy Study of EPI-743 in Children With Leigh Syndrome

Leigh Syndrome

United States
National University Hospital, Singapore

Not yet recruiting

Splint Versus Steroid Randomized Trial

De Quervain Syndrome
University of Minnesota

Completed

Transcranial Magnetic Stimulation for Mal de Debarquement Syndrome

Mal de Debarquement Syndrome

United States
PTC Therapeutics

Completed

Long-Term Safety and Efficacy Evaluation of EPI-743 in Children With Leigh Syndrome

Leigh Syndrome

United States
Aadi Bioscience, Inc.

Withdrawn

ABI-009 (Nab-sirolimus) in Patients With Genetically-confirmed Leigh or Leigh-like Syndrome

Leigh Syndrome
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Azacitidine and Etanercept in Treating Patients With Myelodysplastic Syndromes

Previously Treated Myelodysplastic Syndromes | Secondary Myelodysplastic Syndromes | de Novo Myelodysplastic Syndromes

United States
Taysha Gene Therapies, Inc.

Withdrawn

A Study of the Natural Course of SURF1 Deficiency

Leigh Syndrome

United States
National Cancer Institute (NCI)

Completed

Belinostat in Treating Patients With Myelodysplastic Syndromes

Previously Treated Myelodysplastic Syndromes | Secondary Myelodysplastic Syndromes | de Novo Myelodysplastic Syndromes

United States
University of Minnesota

Withdrawn

WAVES for Mal de Debarquement Syndrome (WAVESMdDS)

Mal de Debarquement Syndrome
University of Minnesota

Withdrawn

Transcranial Electrical Stimulation for Mal de Debarquement Syndrome

Mal de Debarquement Syndrome

United States
Mayo Clinic

Terminated

Evaluation of Autonomic Function in Individuals With Cornelia de Lange Syndrome (CdLS)

Cornelia de Lange Syndrome

United States
University Hospital Plymouth NHS Trust

Recruiting

The SToICAL Study - The Soft Tissue Injection of Corticosteroid And Local Anaesthetic Study (SToICAL)

Carpal Tunnel Syndrome | Trigger Finger | De Quervains Tenosynovitis

United Kingdom
Johns Hopkins University
Cornelia de Lange Syndrome Foundation

Not yet recruiting

Use of N-Acetylcysteine in the Treatment of Repetitive and Self-Injurious Behaviors in Cornelia de Lange Syndrome

Cornelia de Lange Syndrome

United States
Washington University School of Medicine

Recruiting

Continuous Versus Intermittent cARdiac Electrical moNitorinG (CARING)

Long QT Syndrome | Torsades de Pointe Caused by Drug

United States
University Children's Hospital Basel
Swiss National Science Foundation; Fondation Botnar

Completed

Measurement of Lipogenic Flux by Deuterium Resolved Mass Spectrometry Via Non-invasive Breath Analysis (D2OBREATH)

De Novo Lipogenesis (DNL)

Switzerland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Methylprednisolone, Horse Anti-Thymocyte Globulin, Cyclosporine, Filgrastim, and/or Pegfilgrastim or Pegfilgrastim Biosimilar in Treating Patients With Aplastic Anemia or Low or Intermediate-Risk Myelodysplastic Syndrome

Previously Treated Myelodysplastic Syndrome | Myelodysplastic Syndrome | Aplastic Anemia | de Novo Myelodysplastic Syndrome

United States
Novartis

Completed

Pharmacokinetic Study of AEB071 in Patients Following Liver Transplantation

de Novo Liver Transplantation

Germany, Italy, Switzerland
University Hospital, Tours
Astellas Pharma Inc

Unknown

Efficacy and Safety Study of a 4-Month Post-Renal Transplant Dose Reduction of Tacrolimus(ADEQUATE) (ADEQUATE)

De Novo Transplant Disease

France
Cairo University

Not yet recruiting

Phonophoresis Versus Low-Level Laser on Dequervain

de Quervain Tenosynovitis

Egypt
The University of Hong Kong

Completed

Sinew Acupuncture for de Quervain's Tenosynovitis

de Quervain's Tenosynovitis

Hong Kong
Laboratorios Sophia S.A de C.V.

Completed

Phase IV Study to Evaluate the Efficacy of Lagricel® Ofteno PF Compared to Thealoz® Duo After Photorefractive Keratectomy (PRK) (PRO-037)

Photorefractive Keratectomy | Corneal De-epithelialization

Mexico
Khondrion BV
Drug Research Unit Ghent, Belgium

Completed

A Dose-escalating Clinical Trial With KH176

Mitochondrial Disease | MELAS | Leigh Syndrome | LHON | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation

Belgium
Hugo W. Moser Research Institute at Kennedy Krieger...

Recruiting

Behavioral Assessment and Treatment of Problem Behavior in Children With Cornelia de Lange Syndrome

Cornelia de Lange Syndrome

United States
Novartis

Completed

Efficacy and Safety of Enteric-coated Mycophenolate Sodium (EC-MPS) in de Novo Kidney Transplant Recipients

De Novo Kidney Transplant Recipients
The University of Texas Health Science Center,...

Recruiting

The International Registry for Leigh Syndrome

Leigh Disease | Leigh Syndrome | Leigh's Necrotizing Encephalopathy | Subacute Necrotizing Encephalomyopathy | Subacute Necrotizing Encephalomyelopathy

United States
Rigshospitalet, Denmark

Completed

Early Detection of de Novo Cancer in Liver Transplant Recipients (DETECT)

Liver Transplant Disorder | De Novo Cancer
Novartis Pharmaceuticals

Completed

Feasibility and Safety of Early Switch to Everolimus From Cyclosporine in de Novo Renal Transplant Patients

De Novo Renal Transplantation

Norway
Astellas Pharma Inc

Completed

A Study to Assess the Efficacy and Safety of Alefacept in Kidney Transplant Recipients

De Novo Kidney Transplantation

Belgium, France, Netherlands, Spain, Sweden, Austria, Italy, Germany, United Kingdom, Hungary, Poland, Czech Republic
Novartis

Completed

Extension Study on the Efficacy and Safety of Enteric-coated Mycophenolate Sodium Administered in de Novo Kidney Transplant Patients

De Novo Kidney Transplantation
University of California, Davis

Recruiting

Intra-sheath vs Extra-sheath Injection for De Quervain's Tenosynovitis

De Quervain Tenosynovitis

United States
Massachusetts General Hospital
Boston University; Mayo Clinic; Beth Israel Deaconess Medical Center; The Cleveland... and other collaborators

Terminated

A Registry to Determine the Clinical and Genetic Risk Factors for Torsade De Pointes (BA-TdP)

Long qt Syndrome | Torsade de Pointes

United States
Astellas Pharma Inc

Completed

Efficacy and Safety of Two Anti-T-lymphocyte Immune Globulin (ATG-F) Induction Regimens in Anew Kidney Transplant Patients

De Novo Kidney Transplant Patients

China
Astellas Pharma Korea, Inc.

Completed

A Study to Evaluate the Effect of Advagraf Conversion From Prograf in Liver Transplant Subjects (Maple)

de Novo Liver Transplant Subjects

Korea, Republic of
Erasmus Medical Center
Hoffmann-La Roche

Completed

Fixed Dose MMF vs Concentration Controlled MMF After Renal Transplantation

De Novo Renal Transplant Recipient.

France, Spain, Taiwan, Denmark, Australia, United Kingdom, Germany, Canada, Belgium, China, Sweden, Netherlands, Austria, Brazil, Estonia, Lithuania, Norway, Poland, Venezuela
TOPMED
Natural Sciences and Engineering Research Council, Canada; Medicus

Recruiting

New 3D Printed Wrist Orthosis

Carpal Tunnel Syndrome | Rhizarthrosis | Ulnar Nerve Injury | Tendinopathy, Thumb | Tenosynovitis de Quervain | Hand Disease

Canada
Medinol Ltd.

Completed

NIRTRAKS Post-Market Study (NIRTRAKS) (NIRTRAKS)

de Novo Stenotic Lesions in Native Coronary Arteries

United States
Fred Hutchinson Cancer Center

Completed

Chemotherapy in Treating Patients With Myelodysplastic Syndrome Before Donor Stem Cell Transplant (ICT-HCT)

Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Secondary Myelodysplastic Syndrome | de Novo Myelodysplastic Syndrome

United States
National Cancer Institute (NCI)

Completed

Sunitinib in Treating Patients With Myelodysplastic Syndromes or Chronic Myelomonocytic Leukemia

Myelodysplastic Syndromes | Chronic Myelomonocytic Leukemia | Secondary Myelodysplastic Syndromes | de Novo Myelodysplastic Syndromes

Canada, United States
China Medical University Hospital

Recruiting

Using Ultrasound and Acupuncture to Explore the De-qi Location and Reaction of Specific Acupoints

Ultrasound Imaging | de qi of Acupuncture

Taiwan
NYU Langone Health

Completed

Effectiveness of Astym Treatment For de Quervain's Tenosynovitis

de Quervain's Disease

United States
Harbin Medical University
The First Affiliated Hospital with Nanjing Medical University; Peking University... and other collaborators

Active, not recruiting

Safety and Efficacy of Drug-Coated Balloon for De-novo Lesions in Patients With Acute Coronary Syndromes (DCB-ACS) (DCB-ACS)

Coronary Artery Disease | De Novo Stenosis | Clinical Trial | Acute Coronary Syndromes | ACS | DCB | Drug-Coated Balloon

China
Biotronik AG

Completed

First in Man Trial - BIOSOLVE-I (BIOSOLVE-I)

de Novo Lesions in Native Coronary Arteries

Netherlands, Switzerland, Germany, Belgium
Mongi Slim Hospital

Completed

Diaphragm Ultrasound to Predict Weaning Outcomes in Mechanically Ventilated Patients

Accuracy of DE and DTF in Prediction of Extubation Success

Tunisia
University of Chicago
National Cancer Institute (NCI)

Completed

Selinexor in Treating Patients With Intermediate- and High-Risk Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome After Transplant

Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Myelodysplastic Syndrome | Secondary Myelodysplastic Syndrome | de Novo Myelodysplastic Syndrome

United States
National Cancer Institute (NCI)

Active, not recruiting

Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia

Anemia | Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | de Novo Myelodysplastic Syndrome

United States
PTC Therapeutics

Completed

A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy (MIT-E)

Mitochondrial Diseases | Drug Resistant Epilepsy | Leigh Disease | Leigh Syndrome | Mitochondrial Encephalopathy (MELAS) | Pontocerebellar Hypoplasia Type 6 (PCH6) | Alpers Disease | Alpers Syndrome

United States, Spain, United Kingdom, Canada, France, Italy, Poland, Sweden, Japan

Clinical Trials on Síndrome de Leigh

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CROs in Bahamas

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