Search clinical trials for: AT-527 (R07496998)

Total 2573 results

Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Mass Balance Study of AT-527 in Healthy Adult Male Subjects (R07496998)

Healthy Volunteer Study

United States
Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Bronchopulmonary PK of AT-527 (R07496998)

Healthy Volunteer Study

United Kingdom
Hoffmann-La Roche
Atea Pharmaceuticals, Inc.

Terminated

Study to Evaluate the Effects of RO7496998 (AT-527) in Non-Hospitalized Adult and Adolescent Participants With Mild or Moderate COVID-19 (MORNINGSKY)

COVID-19

Switzerland, Turkey, Denmark, Belgium, Japan, Mexico, Argentina, Brazil, Germany, Portugal, Romania, Ukraine
Hoffmann-La Roche
Atea Pharmaceuticals, Inc.

Completed

Study to Evaluate the Effects of AT-527 in Non-Hospitalized Adult Patients With Mild or Moderate COVID-19

COVID-19

Spain, Canada, United Kingdom, Greece, Ireland, Latvia
Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Drug-drug Interaction Study of Rosuvastatin and AT-527 (R07496998)

Healthy Volunteer Study

Canada
Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Drug-drug Interaction Study of Digoxin and AT-527 (R07496998)

Healthy Volunteers Study

Canada
Atea Pharmaceuticals, Inc.

Completed

Study of AT-527 in Healthy Subjects Under Fasting Conditions or With a Meal

Healthy Volunteer Study

Canada
Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Study of AT-527 in Healthy Subjects (R07496998)

Healthy Volunteer Study

Canada
Atea Pharmaceuticals, Inc.

Withdrawn

Study of AT-777 in Healthy Subjects and AT-777 in Combination With AT-527 in HCV-Infected Subjects

Hepatitis C Virus Infection | Hepatitis C | Hepatitis C, Chronic | Chronic Hepatitis C | HCV Infection

Belgium
Atea Pharmaceuticals, Inc.

Completed

Study of AT-527 in Combination With Daclatasvir in Subjects With Hepatitis C Virus (HCV) Infection

Hepatitis C Virus Infection | Hepatitis C | Hepatitis C, Chronic | Chronic Hepatitis C | HCV Infection

Belgium, Mauritius, Moldova, Republic of
Atea Pharmaceuticals, Inc.

Terminated

Safety and Efficacy of AT-527 in Subjects With Moderate Coronavirus Disease (COVID-19) in a Hospital Setting

COVID-19

United States, Argentina, Belgium, Brazil, Egypt, Moldova, Republic of, Romania, South Africa, Spain, Ukraine
Atea Pharmaceuticals, Inc.

Recruiting

Study of Bemnifosbuvir in Subjects With Normal and Impaired Hepatic Function

Hepatic Impairment | Healthy Volunteer

United States
Atea Pharmaceuticals, Inc.

Completed

The Study of Bemnifosbuvir in Healthy Japanese Subjects

Healthy Volunteer Study

United States
Atea Pharmaceuticals, Inc.

Active, not recruiting

SUNRISE-3: Efficacy and Safety of Bemnifosbuvir in High-Risk Outpatients With COVID-19

COVID-19 | SARS CoV 2 Infection

United States, Argentina, Brazil, Canada, Germany, India, Japan, Latvia, Mexico, Netherlands, Pakistan, Philippines, Romania, South Africa, Spain, Sweden, Tunisia, Turkey, United Kingdom
Atea Pharmaceuticals, Inc.

Recruiting

Study of AT-527 in Subjects With Normal and Impaired Renal Function

Renal Impairment | Healthy Volunteer

Canada
Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Effect of Carbamazepine on the Pharmacokinetics (PK) of AT-527

Healthy Volunteer Study

Canada
Atea Pharmaceuticals, Inc.

Completed

Study of AT-527 in Healthy and HCV-Infected Subjects

Hepatitis C | Hepatitis C, Chronic | Chronic Hepatitis C

Belgium, Moldova, Republic of
Atea Pharmaceuticals, Inc.

Recruiting

A Phase 2, Safety and Efficacy of Bemnifosbuvir (BEM) and Ruzasvir (RZR) in Subjects With Chronic HCV

Hepatitis C | Hepatitis C, Chronic | HCV | Chronic Hepatitis C Virus | Hepatic Cirrhosis

Turkey, Brazil, Romania, Canada, Philippines, Pakistan, South Africa, Moldova, Republic of, United States, India, Korea, Republic of, Mauritius
University of Nottingham
University Hospitals of Derby and Burton NHS Foundation Trust

Completed

A Study of Agreement Between Oxygen Saturation Measured by Two Probes in Infants on the Neonatal Unit (Ag-OS)

Neonatal Disease

United Kingdom
Atea Pharmaceuticals, Inc.

Completed

Drug-drug Interaction Study of Ruzasvir and Bemnifosbuvir (AT-527)

Healthy Volunteer Study

Canada
Celldex Therapeutics

Completed

A Study of the PD-L1xCD27 Bispecific Antibody CDX-527 in Patients With Advanced Malignancies

Renal Cell Carcinoma | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Cholangiocarcinoma | Non-small Cell Lung Cancer | Primary Peritoneal Carcinoma | Hepatic Cancer | Bladder Urothelial Carcinoma | Other Solid Tumors | MSI-H Colorectal Cancer

United States
Indiana University

Completed

Effectiveness of Two Different Forms of Marine Oil on Indirect Markers of Muscle Damage and Soreness in Untrained Men

Inflammation; Muscle

United States
Connecticut Children's Medical Center

Completed

B2-Adrenergic Receptor Polymorphisms

Status Asthmaticus

United States
Wake Forest University Health Sciences

Withdrawn

SIRT-1 Antagonism for Endometrial Receptivity (SAFER)

Uterine Diseases | Endometriosis | Infertility Unexplained | Endometrial Diseases | Infertility; Female, Nonimplantation

United States
University of Vienna

Completed

Impact of Hesperetin in Combination With Sucrose on Energy Metabolism

Hunger | Blood Glucose Fluctuations

Austria
Mayo Clinic

Completed

Diphenoxylate / Atropine to Decrease FDG Activity During F-18 FDG PET

Lymphoma
Atea Pharmaceuticals, Inc.
Hoffmann-La Roche

Completed

Effect of Cyclosporine on the Pharmacokinetics (PK) of AT-527 (R07496998)

Healthy Volunteer Study

Canada
AZ Sint-Jan AV

Completed

Catheter Ablation of All Inducible AT Post AF Ablation (INDUCATH)

Atrial Fibrillation | Atrial Tachycardia

France, Belgium, Germany, United Kingdom
Hongpeng Li

Completed

Effects of Positive End-expiratory Pressure on Intracranial Pressure in Patients With Severe Traumatic Brain Injury (PEEP，ICP，CVP)

Traumatic Brain Injury | Mechanical Ventilation Complication
Federal University of São Paulo
Instituto Paulista de Estudos e Pesquisa em Oftalmologia; Eye Clinic Day Hospital...

Completed

Clinical Outcomes After Bilateral Implantation of ZEISS AT LISA TRI AND TRI TORIC IOL

Cataract

Brazil
Atea Pharmaceuticals, Inc.

Completed

Study of Bemnifosbuvir on Cardiac Repolarization in Healthy Subjects

Healthy Volunteer Study

Canada
Galaxia Empírica
Sociedad Española de Neumología y Cirugía Torácica

Recruiting

Triple vs High Dose Inhaled CORticosteroids (TRICORDA)

Asthma

Spain
Hutchison Medipharma Limited

Completed

A Study of the Safety, Tolerability and Pharmacokinetics of HMPL-523

Rheumatoid Arthritis (RA)

Australia
Jin Chen-jin

Completed

Treatment Trial for Acute Central Serous Chorioretinopathy

Acute Central Serous Chorioretinopathy

China
University of Brasilia
University of Burgundy

Completed

Angles of Knee and Hip Joints for Optimization of Neuromuscular Electrical Stimulation of the Quadriceps Femoris Muscle

Electrical Stimulation

Brazil
Centre Hospitalier Régional Metz-Thionville

Recruiting

Quality of Life Evaluation After Cataract Surgery Using 4 Types of Intraocular Lens Implant Combinations (ELVIRA4)

Cataract | Intraocular Lens Implant

France
University of Vienna

Recruiting

Impact Hesperetin in Combination With Sucrose on Blood Glucose Regulation

Hunger | Blood Glucose Fluctuations

Austria
National Cancer Institute (NCI)

Terminated

Phase 2 Study of AT13387 (Onalespib) in ALK+ ALCL, MCL, and BCL-6+ DLBCL

Recurrent Mantle Cell Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent Transformed Non-Hodgkin Lymphoma | Refractory Mantle Cell Lymphoma | Refractory Anaplastic Large Cell Lymphoma | Refractory Transformed Non-Hodgkin Lymphoma | Recurrent...

United States
Amgen

Terminated

Safety, Tolerability, PK, PD, and Efficacy of AMG 427 in Subjects With Relapsed/Refractory Acute Myeloid Leukemia (20170528)

Relapsed/Refractory Acute Myeloid Leukemia (AML)

United States, Korea, Republic of, Australia, Japan, Germany, Canada
YourChoice Therapeutics, Inc.

Recruiting

First in Human Study Evaluating Single Ascending Oral Doses of YCT-529 in Healthy Males

Male Contraception

United Kingdom
Amgen

Terminated

Safety Study of AMG 557 in Subjects With Subacute Cutaneous Lupus Erythematosus

Cutaneous Lupus | Lupus

United States, Australia, Canada
Hutchison Medipharma Limited

Unknown

A Study of Hutchison MediPharma Limited(HMPL)-523 in Patients With Relapsed or Refractory Mature B-cell Neoplasms

Mature B-cell Neoplasms

China
Carl Zeiss Meditec AG

Completed

Combined EDOF / Trifocal

Cataract

Germany, Denmark, Ireland
British Columbia Children's Hospital

Unknown

WOMAC Hip Score in Children and Adolescents With Perthes Disease (WOMAC)

Legg-Calvé-Perthes Disease

Canada
AC Immune SA
Worldwide Clinical Trials

Recruiting

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

Alzheimer's Disease | Prodromal Alzheimer's Disease | Amyloid Plaque | Beta-Amyloid | Alzheimer's Disease in Down Syndrome

United States, Spain, United Kingdom
Duke University

Completed

Hypercapnia: Cognitive Effects and Monitoring

Exercise | Hypercapnia | Immersion | Diving | Nitrogen Narcosis

United States
University of Bonn
DLR German Aerospace Center

Completed

Influence of Ambient Temperature on Resting Energy Expenditure of Healthy Adults

Resting Energy Expenditure

Germany
University Hospital Augsburg

Recruiting

Dose Efficiency of Modern CT Scanners in Oncologic Scans

Neoplasms | Neoplasm Metastasis | Metastatic Cancer

Germany
Southeast University, China

Completed

Different PEEP Settings of COVID-19 Induced ARDS

COVID-19 | Acute Respiratory Distress Syndrome | Mechanical Ventilation Pressure High

China
Merck Sharp & Dohme LLC

Recruiting

Safety and Pharmacokinetic Study of Oral MK-8527 QM in Participants at Low-Risk for HIV-1 Infection (MK-8527-007)

HIV | HIV Pre-exposure Prophylaxis

United States, South Africa, Israel

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