Search clinical trials for: Biologic Agent

Total 188114 results

Hoffmann-La Roche

Completed

Retrospective Analysis of Pulmonary Arterial Hypertension (PAH) and Related Complications in Juvenile Idiopathic Arthritis (JIA) Participants Treated With Biologic and Non-biologic Disease-modifying Anti-rheumatic Drugs (DMARDs)

Juvenile Idiopathic Arthritis
University Hospital, Lille

Completed

Biological Meshes in Infected Fields: a Randomized Controlled Trial (SIMBIOSE)

Ventral Hernia

France
University of Calgary
University of British Columbia; B. Braun Medical Inc.

Completed

Blood Pressure Guided Biofeedback on Hemodialysis and the Reduction of IntraDialytic Hypotension (BP-RIDH)

Hypotension

Canada
Janssen Biotech, Inc.

Completed

Ustekinumab Safety and Surveillance Program Using the Ingenix NHI Database

Psoriasis
Nanfang Hospital of Southern Medical University
Southern Medical University, China

Unknown

Long-term Prognosis and Quality of Life in Early Rheumatoid Arthritis Patients Treated by 2015 ACR Guideline (LELAND) (LELAND)

Rheumatoid Arthritis
Psoriasis Treatment Center of Central New Jersey
Janssen Scientific Affairs, LLC

Completed

An Outcomes Study to Determine the Reasons Patients on Biologic Therapy Discontinue Treatment and Fail to Follow-up With Their Providers

Psoriasis

United States
University of Calgary
Medtronic

Recruiting

Performance of Biologic Mesh Materials in Abdominal Wall Reconstruction

Ventral Hernia

Canada
Janssen Biotech, Inc.

Completed

Golimumab Safety and Surveillance Program Using the Ingenix NHI Database

Rheumatoid Arthritis | Arthritis, Psoriatic | Ankylosing Spondylitis
DermTech

Recruiting

A Prospective Sample Collection Study Using Non-invasive Methods to Investigate Biomarkers in AD Patients

Atopic Dermatitis

United States
University of Missouri-Columbia

Completed

A Biologic Joint Replacement Strategy for Knee Trauma and Post-Traumatic Osteoarthritis

Knee Osteoarthritis | Post-traumatic Osteoarthritis

United States
Royal College of Surgeons, Ireland
New York University; The Charitable Infirmary Charitable Trust

Not yet recruiting

This is a 6-month Observational Study. Patients Included Will be Those Referred With a Possible Diagnosis or an Established Diagnosis of Asthma. It Will Look at the Association of the Asthma Microbiome and Disease Characteristics, Severity and Treatment Response.

Asthma
Miromatrix Medical Inc.

Completed

MIRODERM H2H DFU Study (H2H-DFU)

Diabetic Foot Ulcer

United States
Assiut University

Not yet recruiting

Outcome of Treatment of Uveitis With Biologic Drugs in Resistant Cases Vogt-koyanagi-Harada Disease

Uveitis
Assistance Publique - Hôpitaux de Paris

Completed

Validity of a French Version of the Severe Asthma Questionnaire (TRAQUE)

Asthma

France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Identification of Prognostic Factors and New Therapeutic Targets in Cutaneous Lymphomas (LYMPHOTEQ)

Cutaneous Lymphoma
University Hospital, Brest

Not yet recruiting

Prospective Cohort Study on the Determinants of Venous THromboembolic Recurrence (BREIZH-Cohorte)

Thromboembolic Venous Disease

France
University of Nebraska

Completed

Arteriovenous Fistula Tissue Bank for Pre- and Post-Fistula Placement Specimens

Kidney Failure, Chronic

United States
National Alliance for Sickle Cell Centers
Beam Therapeutics Inc.

Recruiting

Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

Sickle Cell Trait

United States
Jennifer Jones
Nova Scotia Health Authority

Recruiting

Improving Patient Outcomes Through the Implementation of an IBD Biologic Care Pathway

Inflammatory Bowel Diseases | Crohn Disease | Ulcerative Colitis

Canada
GenVec

Completed

Radiotherapy, Cetuximab, and Injections of TNFerade™ Biologic for Elderly or Frail Patients With Head and Neck Cancer

Head and Neck Cancer | Head and Neck Neoplasms

United States
NuVasive

Completed

Osteocel® Plus in Anterior Cervical Discectomy and Fusion (ACDF)

Degenerative Disc Disease in Cervical Spine

United States
Wake Forest University Health Sciences

Recruiting

Implantation Of Vaginal Construct For Patients With Vaginal Aplasia (TEV)

Congenital Mullerian Duct Anomaly

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Recruiting

Collecting and Storing Tissue Samples From Women With or Without Breast Cancer

Breast Cancer

United States
University of Arizona
National Cancer Institute (NCI)

Recruiting

Arizona Cancer Center Biospecimen Repository

Cancer

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0309, Repository: Blood/Bone Marrow From Pts. With Myeloma, WM, Amyloidosis, or MGUS.

Multiple Myeloma | Amyloidosis | Waldenstrom's Macroglobulinemia | Monoclonal Gammopathy of Undetermined Significance | Smoldering Myeloma

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S9910, Collecting and Storing Blood and Bone Marrow Samples From Patients With Hematologic Cancer

Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Neoplasms

United States
Aeris Therapeutics

Completed

Biologic Lung Volume Reduction (BLVR) Phase 2 Homogeneous Study

Homogeneous Emphysema

United States
B.Braun Avitum AG

Recruiting

Prospective, Multicentre, Randomized, Controlled, Cross-over Study on the Safety and Performance of the Biologic Fusion Option of DialogiQ Compared to Haemodialysis Without Biologic Fusion in Hypotension Prone Patients on Maintenance Haemodialysis

Renal Dialysis

Italy
GenVec

Completed

A Study of TNFerade™ Biologic With Concomitant Radiotherapy, Fluorouracil, and Hydroxyurea (TNF-FHX) in Patients With Head and Neck Cancer

Head and Neck Cancer | Head and Neck Neoplasms

United States
National Jewish Health

Recruiting

Identification of Pathways to Mitigate Immune-Related Adverse Events With Cancer Immunotherapy

Cancer

United States
The University of Texas Health Science Center,...

Completed

Mesh Type in Ventral Hernia Repair

Ventral Hernia

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Collecting Tissue Samples From Patients With Leukemia or Other Blood Disorders Planning to Enroll in an ECOG Leukemia Treatment Clinical Trial

Lymphoma | Leukemia

United States
Assistance Publique - Hôpitaux de Paris

Completed

Mesh Reinforcement During Temporary Stoma Closure After Sphincter-Saving Rectal Cancer Surgery (MEMBO)

Incisional Hernia After Diverting Stoma Closure

France
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S9925: Collecting and Storing Samples From Patients With Lung Cancer

Lung Cancer

United States
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

A Study of IBI112 in Chinese Patients With Psoriasis Who Were Previously Treated With Biologics

Psoriasis

China
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Active, not recruiting

Collecting and Storing Blood, Bone Marrow, and Other Samples From Patients With Acute Leukemia, Chronic Leukemia, or Myelodysplastic Syndromes

Acute Leukemia | Myelodysplasia | Chronic Leukemia

United States
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

SWOG-8947 Collecting and Storing Blood Samples From Patients With Previously Untreated Non-Hodgkin Lymphoma

Lymphoma

United States
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Collecting and Storing Tissue Samples From Patients With Head and Neck Cancer

Head and Neck Cancer

United States, Canada
Pfizer

Completed

Study Evaluating the Effects of IMA-638 on Allergen-Induced Airway Responses in Subjects With Mild Atopic Asthma

Asthma

Canada
University of Athens

Unknown

Effects of Interleukin-6 Inhibition on Vascular, Endothelial and Left Ventricular Function in Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Greece
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Completed

Tissue Sample Collection From Patients With Fanconi Anemia

Unspecified Childhood Solid Tumor, Protocol Specific | Unspecified Adult Solid Tumor, Protocol Specific | Fanconi Anemia

United States
Tuen Mun Hospital

Completed

Safety and Retention Rate of the JAK and TNF Inhibitors in Rheumatoid Arthritis: a Real-life Experience

Rheumatoid Arthritis | Drug Use

China
NuVasive

Completed

Osteocel® Plus in eXtreme Lateral Interbody Fusion (XLIF®)

Back Pain | Degenerative Disc Disease

United States
Eisai Inc.
Halozyme Therapeutics

Terminated

Study of Eribulin Mesylate in Combination With PEGylated Recombinant Human Hyaluronidase (PEGPH20) Versus Eribulin Mesylate Alone in Subjects With Human Epidermal Growth Factor Receptor 2 (HER2)-Negative, High-Hyaluronan (HA) Metastatic Breast Cancer (MBC)

Metastatic Breast Cancer

United States
AstraZeneca

Recruiting

A Retrospective Chart Review to Investigate Clinical Remission in Patients With Severe Asthma Treated With Biologics in the United Kingdom National Health Service (REMISSION UK)

Asthma

United Kingdom
University Hospital, Lille

Completed

Identification of New Markers in the Hypereosinophilic Syndrome (SHE)

Hypereosinophilic Syndrome

France
The University of Texas Health Science Center,...

Terminated

Tissue Reinforcement of Incisional Closure Among High Risk Patients

Wound Complication

United States
GenBasix Incorporated

Unknown

Blood Sample Collection and Health Information Collection From Patients With Invasive Breast Cancer and Their Brothers and Sisters

Breast Cancer

United States
Walter Reed National Military Medical Center

Recruiting

Microbiome Population Adaptation Study (OLIMPAS)

Amputation With Osseointegration

United States
El-Hussuna, Alaa, M.D.

Completed

Anti Tumor Necrosis Factor Alpha Agents and Surgical Stress Response

Inflammatory Bowel Diseases

Denmark

3

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