Search clinical trials for: DiVA

Total 227 results

Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Relative Bioavailability of a Fixed-dose Combination Tablet of VX-121/Tezacaftor/Deutivacaftor

Cystic Fibrosis

United States
Vertex Pharmaceuticals Incorporated

Completed

A Study of Vanzacaftor/Tezacaftor/Deutivacaftor (VNZ/TEZ/D-IVA) in Healthy Adult Panelists

Cystic Fibrosis

United States
Vertex Pharmaceuticals Incorporated

Enrolling by invitation

Evaluation of Long-Term Safety and Efficacy of Vanzacaftor/Tezacaftor/Deutivacaftor in Cystic Fibrosis Participants 1 Year of Age and Older

Cystic Fibrosis

United States, Australia, Germany, Sweden, Switzerland, France, Netherlands, United Kingdom
Chang Gung Memorial Hospital

Recruiting

Negative Pressure Ventilation-rehabilitation on Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | Acute Exacerbation of COPD

Taiwan
University of Florida

Recruiting

Effect of Position and Anesthetic Choice in Intraocular Pressure in Robotic GYN (Gynecologic) Oncology Patients

Intraocular Pressure | Oncology

United States
Medical University of Vienna

Recruiting

Investigation of Neurovascular Coupling in Glaucoma Patients and Healthy Subjects

Ocular Hypertension | Glaucoma, Open-Angle | Normal Tension Glaucoma

Austria
Vertex Pharmaceuticals Incorporated

Completed

A Study of the Effects of Lumacaftor/Ivacaftor (LUM/IVA) on Exercise Tolerance in Subjects With Cystic Fibrosis (CF), Homozygous for the F508del-CFTR Mutation

Cystic Fibrosis

Australia, United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

Lumacaftor/Ivacaftor Combination Therapy in Subjects With CF Who Have an A455E CFTR Mutation

Cystic Fibrosis

Netherlands
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Trebananib in Treating Patients With Persistent or Recurrent Endometrial Cancer

Recurrent Uterine Corpus Carcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Endometrial Adenocarcinoma | Endometrial Adenosquamous Carcinoma | Endometrial Endometrioid Adenocarcinoma, Variant With Squamous Differentiation | Endometrioid Stromal Sarcoma

United States
University Medicine Greifswald
SDI Limited

Completed

Fluoride Therapies on Hypersensitive Carious Lesions in Primary Teeth

Dentin Hypersensitivity | Active Dental Caries

Germany
Vertex Pharmaceuticals Incorporated

Active, not recruiting

Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age

Cystic Fibrosis

United States, Australia, Germany, Sweden, Switzerland, France, Netherlands, United Kingdom
Vertex Pharmaceuticals Incorporated

Active, not recruiting

A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy

Cystic Fibrosis

United States, Spain, United Kingdom, Belgium, Netherlands, Denmark, Israel, New Zealand, France, Australia, Ireland, Germany, Sweden, Canada, Czechia, Switzerland, Portugal, Italy, Austria, Hungary, Norway, Poland, Greece
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Ivacaftor in Subjects With Cystic Fibrosis Who Are Less Than 24 Months of Age and Have an Ivacaftor-Responsive CFTR Mutation

Cystic Fibrosis

United States, Canada, United Kingdom, Australia, Ireland
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate Efficacy of Ivacaftor in Subjects With Cystic Fibrosis Who Have a 3849 + 10KB C→T or D1152H CFTR Mutation

Cystic Fibrosis

Israel
Vertex Pharmaceuticals Incorporated

Approved for marketing

Tezacaftor/Ivacaftor Combination Therapy Expanded Access Program for Patients 12 Years of Age and Older With Cystic Fibrosis

Cystic Fibrosis
Instituto do Coracao

Unknown

Effect of Sevoflurane in Postoperative Troponin I Levels in Children Undergoing Congenital Heart Defects Surgery

Congenital Heart Defects

Brazil
Al-Azhar University

Completed

Evaluation of the Remineralizing and Antibacterial Effect of Natural Versus Synthetic Materials on Deep Carious Dentin

Dentin Caries

Egypt
Technical University of Munich
Ludwig-Maximilians - University of Munich

Recruiting

All Eyes on PCS - Analysis of the Retinal Microvasculature in Patients With Post-COVID-19 Syndrome

Endothelial Dysfunction | Long Covid19 | Post COVID-19 Condition

Germany
Ain Shams University

Completed

Awareness in Old Aged Patients During Laryngoscopy and Intubation Using Isolated Forearm Technique

Awareness, Anesthesia | Inhalation; Gas | Recall Phenomenon

Egypt
Vertex Pharmaceuticals Incorporated

Completed

A Rollover Safety Study of Lumacaftor/Ivacaftor in Subjects Aged 2 Years and Older With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation

Cystic Fibrosis

United States, Canada
Vertex Pharmaceuticals Incorporated
Moderna, Inc

Recruiting

A Phase 1/2 Study of VX-522 in Participants With Cystic Fibrosis (CF)

Cystic Fibrosis

United States, United Kingdom, Australia, Canada
Vertex Pharmaceuticals Incorporated

Completed

Long-term Safety of Lumacaftor/Ivacaftor in Subjects With Cystic Fibrosis Who Are Homozygous for F508del and 12 to <24 Months of Age at Treatment Initiation

Cystic Fibrosis

United States, Canada
Vertex Pharmaceuticals Incorporated

Completed

Safety and Pharmacokinetic Study of Lumacaftor/Ivacaftor in Participants 1 to Less Than 2 Years of Age With Cystic Fibrosis, Homozygous for F508del

Cystic Fibrosis

United States, Canada
Xuzhou Medical University

Unknown

Hemodynamics and Vital Organ Function in Intracerebral Hemorrhage

Intracerebral Hemorrhage | Balanced Anesthesia | Total Intravenous Anesthesia

China
Menoufia University

Completed

Anaesthesia for Laparoscopic Sleeve Gastrectomy

Obese
Carilion Clinic

Enrolling by invitation

Total Intravenous Anesthesia With Propofol vs. General Anesthesia in Outpatient Shoulder Arthroscopic Surgeries (TIVA)

Rotator Cuff Injuries | Anesthesia | Orthopedic Disorder | Rotator Cuff Tears | Sports Injury

United States
Vertex Pharmaceuticals Incorporated

Completed

A Study to Explore the Impact of Lumacaftor/Ivacaftor on Disease Progression in Subjects Aged 2 Through 5 Years With Cystic Fibrosis, Homozygous for F508del

Cystic Fibrosis

Germany
Bezmialem Vakif University

Completed

Effects of TIVA and Inhalation Anesthesia on Oxidative Stress Factors During Hypotensive Anesthesia

Oxidative Stress | Anesthesia

Turkey
Vertex Pharmaceuticals Incorporated

Terminated

Study to Evaluate the Safety and Efficacy of CTP-656 in Patients With Cystic Fibrosis With CFTR Gating Mutations

Cystic Fibrosis

United States
Dimerix Bioscience Pty Ltd

Recruiting

A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB (ACTION3)

FSGS

United States, Argentina, Australia, Denmark, France, Hong Kong, New Zealand, Spain, Taiwan, United Kingdom, Brazil
Vertex Pharmaceuticals Incorporated

Completed

Rollover Study to Evaluate the Safety and Efficacy of Long-term Treatment With Lumacaftor in Combination With Ivacaftor

Cystic Fibrosis

United States, France, United Kingdom, Germany, Belgium, Denmark, Canada, Australia, Sweden
Wake Forest University Health Sciences

Recruiting

Total Intravenous Anesthesia (TIVA)/Sevoflurane Initiated Intravenous Anesthesia (SIIVA) in Pediatric Patients

Extubation

United States, Australia
Ohio State University

Completed

Safety and Efficacy of Using SightSaver Visual Evoked Potential (VEP) for VEP Monitoring in Prone Spine Surgery (SightSaver)

Ischemic Optic Neuropathy

United States
Medical University of Vienna

Recruiting

Retinal Neurovascular Coupling in Patients Previously Infected With COVID-19

COVID-19 | Post-COVID-19 Syndrome

Austria
Vertex Pharmaceuticals Incorporated

Completed

A Study Evaluating Safety and Pharmacokinetics of VX-440 in Combination With Tezacaftor/Ivacaftor in Healthy Adult Subjects

Cystic Fibrosis

United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-809 Alone and in Combination With VX-770 in Cystic Fibrosis (CF) Patients Homozygous or Heterozygous for the F508del-CFTR Mutation

Cystic Fibrosis

United States, France, United Kingdom, Germany, Australia, New Zealand, Belgium
Clinical Hospital Centre Zagreb

Recruiting

Differences in Speed of Recovery From Anesthesia for Intraoral Surgery (PSIOS)

Intraoral Tumor

Croatia
Yeungnam University College of Medicine

Completed

TIVA and VIMA on Blood Glucose and Insulin Levels in Lung Lobectomy Patients

Hyperglycemia Stress

Korea, Republic of
Beijing Tiantan Hospital

Completed

Desflurane and Brain Relaxation in Craniotomy

Supratentorial Tumor

China
Yonsei University

Completed

The Effect of Volatile Anesthesia and Total Intravenous Anesthesia on Shedding of the Endothelial Glycocalyx in Patients Undergoing Mastectomy and Breast Reconstruction Using Deep Inferior Epigastric Artery Perforator Free Flap

Deep Inferior Epigastric Artery Perforator Flap Breast Reconstruction

Korea, Republic of
Cairo University

Recruiting

Clinical Evaluation of SDF Combined With KI Versus SDF in Management of Class I Carious Lesions

Carious Lesion

Egypt
Inonu University

Completed

The Effect of Sevoflurane and Desflurane on Clara Cell Protein on the Lung

Lung Injury | Inhalation Anesthesia

Turkey
Duke University
US Department of Veterans Affairs

Completed

Cognitive Effects of Inhalational Versus Intravenous General Anesthesia in the Elderly

Knee Osteoarthritis | Hip Osteoarthritis | Cervical Spondylosis | Lumbar Spondylosis

United States
Universidad de Valparaiso

Completed

Methadone for Postoperative Pain

Pain, Postoperative

Chile
Vertex Pharmaceuticals Incorporated

Terminated

A Pilot Study to Evaluate the Use of Smart Adherence Technology to Measure Lumacaftor/Ivacaftor Adherence in CF Subjects Homozygous for the F508del CFTR Mutation

Cystic Fibrosis

United States, Canada
Yonsei University

Completed

The Effect of Total Intravenous Anesthesia and Volatile Anesthesia on Shedding of the Endothelial Glycocalyx in Patients Undergoing Laparoscopic or Robotic Assisted Gastrectomy

Gastrostomy

Korea, Republic of
Vertex Pharmaceuticals Incorporated

Completed

A Study Evaluating the Safety and Efficacy of VX-440 Combination Therapy in Subjects With Cystic Fibrosis

Cystic Fibrosis

United States, Canada, United Kingdom, Australia, Spain, Germany, Italy, Austria, Belgium, Denmark
Benha University

Completed

Total Intravenous Anesthesia Versus Inhalation Anesthesia on Postoperative Liver Function

Laparoscopic Sleeve Gastrectomy

Egypt
Vanderbilt University

Completed

Glimepiride Induced Insulin Secretion Will be Inhibited by Hypoglycemia

Type 2 Diabetes
Ospedale San Raffaele

Unknown

Fundus Oculi and Erectile Dysfunction

Erectile Dysfunction

Italy

Search clinical trials for: DiVA

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