Search clinical trials for: GM1

Total 1115 results

General Hospital of Shenyang Military Region
The Third Xiangya Hospital of Central South University

Completed

An Exploratory Study of Ganglioside GM1 in Acute Ischemic Stroke

Stroke, Ischemic

China
Fudan University

Unknown

Treatment of Cerebral Radiation Necrosis With GM1, a Prospective Study

MRI | Nasopharyngeal Carcinoma | Radiotherapy | Cerebral Radiation Necrosis

China
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Finding an Effective Dose of GM1 to Reduce or Prevent Neuropathy (Numbness or Weakness) Due to Treatment With Paclitaxel (Phase II)

Anatomic Stage IV Breast Cancer AJCC v8 | Chemotherapy-Induced Peripheral Neuropathy | Metastatic Breast Carcinoma

United States
InnoMedica Schweiz AG

Active, not recruiting

Safety Evaluation of Intravenous Talineuren (TLN) in Parkinson's Disease-affected Patients (NEON)

Parkinson Disease

Switzerland
Thomas Jefferson University
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

GM1 Ganglioside Effects on Parkinson's Disease

Parkinson Disease

United States
Peking University Cancer Hospital & Institute
Peking University First Hospital; Peking Union Medical College Hospital; Cancer... and other collaborators

Unknown

Monosialoganglioside Preventing Neurotoxicity Induced by Albumin-bound Paclitaxel Chemotherapy in Lung Cancer Patients

Neurotoxicity

China
Asan Foundation

Completed

Safety, Pharmacokinetics, Biodistribution, and Diagnostic Performance of [18F]GP1 PET in Thromboembolism

Thromboembolism

Korea, Republic of
Sun Yat-sen University
Southern Medical University, China

Unknown

Monosialoganglioside(GM1) Preventing Neurotoxicity Induced by Cisplatin Contained Chemotherapy in NSCLC Patients

Non-small Cell Lung Cancer

China
Sun Yat-sen University

Completed

Effect of GM1 in Prevention of Taxanes Induced Neurotoxicity in Operable Breast Cancer

Breast Cancer

China
Lovisenberg Diakonale Hospital
University of Oslo; Oslo University Hospital; Icahn School of Medicine at Mount... and other collaborators

Recruiting

Cognitive Rehabilitation in Post-COVID-19 Condition (TRAINCOVID)

COVID-19

Norway
University of Zurich
Life Molecular Imaging SA

Terminated

Evaluation of a New Imagingtechnologie for Thrombosis (PET-GP1_1)

Deep Vein Thrombosis | Abdominal Aortic Aneurysm

Switzerland
Sykehuset Innlandet HF
University of Oslo

Completed

Goal Management Training for Patients With Schizophrenia or High Risk for Schizophrenia

Neurocognitive Disorders | Schizophrenia

Norway
Terence Flotte
Massachusetts General Hospital; University of Massachusetts, Worcester

Active, not recruiting

A Dose-escalation and Safety & Efficacy Study of AXO-AAV-GM2 in Tay-Sachs or Sandhoff Disease

Tay-Sachs Disease | Sandhoff Disease

United States
Northwestern University

Completed

Stability of the Medial Pivot Total Knee Prosthesis

Osteoarthritis of Knee

United States
Celltrion

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CT-G20 or CT-G11 and Food Effect of CT-G20 in Human Participants

Healthy

Korea, Republic of
Medacta International SA

Recruiting

The Medacta GMK SpheriKA Post-Marketing Surveillance Study

Arthropathy | Knee Replacement

France, Italy, Switzerland
GlycoMimetics Incorporated

Terminated

A Study to Determine Safety and Tolerability of GMI-1359 in Subjects With HR+ Metastatic Breast Cancer

Breast Cancer | Breast Cancer Metastatic | HR+ Metastatic Breast Cancer

United States
McGill University

Unknown

Goal Management Training, Executive Functions and HIV

Hiv

Canada
University of Pittsburgh
National Institute of Mental Health (NIMH); Kaiser Foundation Research Institute

Withdrawn

Bridging the Gap to Improve Mental Health Treatment Utilization

Depression | Anxiety | Suicidal Ideation | Adolescent Behavior

United States
University of Edinburgh
British Heart Foundation; Life Molecular Imaging SA

Completed

18F-GP1 PET-CT to Detect Bioprosthetic Aortic Valve Thrombosis

Aortic Valve Disease | Thrombosis Cardiac

United Kingdom
GlycoMimetics Incorporated

Completed

Study of Intravenous GMI-1070 in Adults With Sickle Cell Disease

Sickle Cell Disease

United States
McMaster University
Workplace Safety and Insurance Board

Not yet recruiting

Trauma-Informed Goal Management Training for Public Safety Personnel (PSP) With Post-traumatic Stress Disorder (PTSD)

Post-Traumatic Stress Disorder
Changchun GeneScience Pharmaceutical Co., Ltd.
Syneos Health

Recruiting

A Study to Assess Safety and Tolerability of GS1-144 in Healthy Volunteers

Vasomotor Symptoms | Adult Healthy Volunteers

Australia
GlycoMimetics Incorporated

Completed

Placebo-controlled Single Dose Study to Evaluate Safety and Pharmacokinetics of GMI-1271 in Healthy Volunteers

Healthy Adult Subjects

United States
International Centre for Diarrhoeal Disease Research...
United States Agency for International Development (USAID)

Not yet recruiting

Assessing the Effectiveness of Strengthening the Growth Monitoring and Promotional Activities in Rural Bangladesh (GMP)

Nutritional Status
Johnson & Johnson Consumer and Personal Products...

Completed

Clinical Evaluation of Effects of an Investigational Tampon on Vaginal Microflora

Vaginal Microflora

United States
Krystal Biotech, Inc.

Active, not recruiting

Topical KB105 Gene Therapy for the Treatment of TGM1-deficient Autosomal Recessive Congenital Ichthyosis (ARCI)

TGM-1 Related Autosomal Recessive Congenital Ichthyosis

United States
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of IV Doses of Rivipansel in Subjects With Moderate Hepatic Impairment and in Healthy Subjects With Normal Hepatic Function

Moderate Hepatic Impairment | Normal Hepatic Function

United States
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of IV Doses of Rivipansel on Subjects With Renal Impairment and in Healthy Subjects

Healthy | Renal Impairment

United States
Changchun GeneScience Pharmaceutical Co., Ltd.

Recruiting

A Phase I Clinical Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Oral Dose Escalation of GS1-144 Tablets and the Effects of Food on the Pharmacokinetics of GS1-144 in a Chinese Population

Healthy Volunteer | Vasomotor System; Labile

China
Oslo University Hospital
Medacta International SA

Active, not recruiting

Stability of Uncemented Medially Stabilized TKA

Knee Osteoarthritis

Norway
Abbott Medical Devices

Completed

Absorb GT1 Japan PMS

Myocardial Ischemia | Coronary Artery Disease | Angina Pectoris | Ischemic Heart Disease | Coronary Artery Occlusion

Japan
Northwestern University

Completed

Total Knee Replacement Component Alignment Using Manual Versus Custom Instrumentation

Osteoarthritis of Knee

United States
GlycoMimetics Incorporated

Terminated

Safety of Rivipansel (GMI-1070) in the Treatment of One or More Vaso-Occlusive Crises in Hospitalized Subjects With Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Anemia | Vaso-occlusive Crisis | Pain Crisis | Sickle Cell Disorders

United States, Canada
GlycoMimetics Incorporated

Completed

A Study to Evaluate the Effect of Age on the Pharmacokinetics, Safety and Tolerability of IV Rivipansel.

Healthy

United States
GlycoMimetics Incorporated
Celerion

Completed

Placebo-Controlled Single Dose Study to Evaluate Safety and Pharmacokinetics of GMI-1359 in Healthy Volunteers

Healthy

United States
Medacta International SA

Active, not recruiting

The Medacta International GMK Sphere Post-Marketing Surveillance Study

Arthritis | Rheumatoid Arthritis | Avascular Necrosis | Traumatic Arthritis | Poly-arthritis

Belgium, United Kingdom
St. Ambrose University

Completed

Graded Motor Imagery and Fall Risk in Older Adults (GMI)

Balance | Fall Risk

United States
University of Edinburgh
British Heart Foundation

Completed

In-vivo Thrombus Imaging With 18F-GP1, a Novel Platelet PET Radiotracer (iThrombus)

Myocardial Infarction | Stroke | Thrombosis | Transient Ischemic Attack | Pulmonary Embolism | STEMI | NSTEMI - Non-ST Segment Elevation MI | DVT | PET | Atherothrombosis | Prosthetic Valve Thrombosis

United Kingdom
Jan Stubberud
University of Oslo; NYU Langone Health; University of Toronto; Rotman Research... and other collaborators

Completed

Cognitive Rehabilitation in Patients With Spina Bifida

Executive Dysfunction | Spina Bifida | Cognitive Deficits

Norway
Medical University of Graz
Menarini Group

Completed

Performance Study to Test the GlucoMen®Day System Using Intravascular and Subcutaneous Microdialysis in Subjects With Type 1 Diabetes

Type 1 Diabetes

Austria
Agency for Healthcare Research and Quality (AHRQ)
The Commonwealth Fund; California HealthCare Foundation

Completed

Improving Diabetes Efforts Across Language and Literacy (IDEALL)

Diabetes

United States
University of Texas at Austin

Completed

The Impact of a Technology-enabled Decision Aid, for Patients With Hip and Knee Osteoarthritis on Decision Quality, Level of Shared Decision-making, Patient Satisfaction and Magnitude of Limitations

Osteoarthritis, Knee

United States
University of Edinburgh
NHS Lothian

Recruiting

The "MyoThrombus" Study

Stroke | Thrombosis | STEMI | Left Ventricular Thrombus

United Kingdom
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR); FDC Foundation

Withdrawn

Goal Management Training in Individuals With PTSD

PTSD | Cognitive Impairment | Cognitive Dysfunction | Cognitive Deficit | Post-traumatic Stress Disorder

Canada
David F. Scott, MD
Medacta USA

Active, not recruiting

Medacta GMK Sphere® vs. Medacta GMK PS Post-Market Outcomes Study

Osteoarthritis | Osteoarthritis, Knee | Joint Disease

United States
University of Tromso
University Hospital of North Norway

Recruiting

A Comparison of Two Treatments for CRPS and Changes in Resting-State Connectivity of Cerebral Networks.

Complex Regional Pain Syndrome

Norway
Medacta International SA

Recruiting

Clinical Utility and Gait Analysis of NextAR System AUS

Total Knee Arthroplasty

Australia
Sun Yat-sen University

Recruiting

GM1 Prophylaxis for WBRT Related Cognitive Dysfunction (GLORY)

Breast Cancer | Cognitive Impairment | Brain Metastases | Radiotherapy Side Effect | Gangliosidosis, GM1

China
Medacta International SA

Recruiting

The Medacta International GMK Sphere Cementless Post-Marketing Surveillance Study

Arthritis | Rheumatoid Arthritis | Avascular Necrosis | Traumatic Arthritis | Poly-arthritis

France, Switzerland

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