Search clinical trials for: RM-493

Total 563 results

Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide in a Single Patient With Partial Lipodystrophy

Obesity | Hypertriglyceridemia

United States
Rhythm Pharmaceuticals, Inc.

Active, not recruiting

Long Term Extension Trial of Setmelanotide

Obesity Associated With Defects in Leptin-melanocortin Pathway

United States, Netherlands, Canada, Germany, United Kingdom, France, Greece, Spain
Rhythm Pharmaceuticals, Inc.

Completed

Phase 1b/2a Study to Evaluate Safety and Efficacy of Setmelanotide in Obese Patients

Overweight and Obesity

United States
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide for the Treatment of Leptin Receptor (LEPR) Deficiency Obesity

Leptin Receptor Deficiency Obesity

Netherlands, Germany, United Kingdom, Canada, France, Réunion
Rhythm Pharmaceuticals, Inc.

Completed

Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RM-493 Administered to Healthy, Obese, Non-diabetic Volunteers

Overweight | Obese
Rhythm Pharmaceuticals, Inc.

Completed

Phase 2 Trial to Evaluate Safety and Efficacy of Setmelanotide (RM-493) in Obese Participants With Prader-Willi Syndrome

Prader-Willi Syndrome

United States
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Participants With Moderate to Severe Obesity

Bardet Biedl Syndrome (BBS) | Alström Syndrome (AS)

United States, United Kingdom, France, Canada, Puerto Rico, Spain
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide Phase 2 Treatment Trial in Participants With Rare Genetic Disorders of Obesity

Obesity | Genetic Obesity | Obesity Due to Melanocortin 4 Receptor Deficiency

United States, United Kingdom, Germany, Netherlands, France, Canada, Greece, Israel, Spain
Charite University, Berlin, Germany

Unknown

RM-493 Treatment Trial in Proopiomelanocortin (POMC) Deficient Patients

Homozygous or Compound Heterozygous POMC, LEPR or PCSK1 Gene Mutation

Germany
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide for the Treatment of Early-Onset Pro-Opiomelanocortin (POMC) Deficiency Obesity

Pro-opiomelanocortin (POMC) Deficiency Obesity

Belgium, United States, Canada, France, Germany, Spain, United Kingdom
Rhythm Pharmaceuticals, Inc.
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Effects of RM-493 on Energy Expenditure in Obese Individuals

Obesity | Morbid Obesity

United States
Rhythm Pharmaceuticals, Inc.

Completed

Phase 2 Study to Evaluate Safety and Efficacy of RM-493 in Obese Participants

Overweight

United States
Rhythm Pharmaceuticals, Inc.

Enrolling by invitation

A Trial of Setmelanotide in Acquired Hypothalamic Obesity

Hypothalamic Obesity

United States, Canada, United Kingdom, Germany, Netherlands
Assiut University

Completed

Ultrasonographic Assessment of Lung Recruitment Maneuvers in Children Undergoing Lengthy Microsurgery Operations (RM)

Intraoperative Complications

Egypt
Purdue University

Completed

Effects of Proportioning Meat and Plant-based Protein-rich Foods on Cardiovascular Disease Risk Factors (S58)

Cardiovascular Risk Factor | Healthy Diet

United States
Rhythm Pharmaceuticals, Inc.

Recruiting

A Study of RM-718 in Healthy Subjects and in Patients With HO

Hypothalamic Obesity

United States
University Hospital, Clermont-Ferrand

Completed

Diffuse Acute Respiratory Distress Syndrome (ARDS), Recruitment Maneuver, and sRAGE (DAMAGE Study) (DAMAGE)

Acute Respiratory Distress Syndrome

France
Steven J. Hardy

Completed

Feasibility and Efficacy of a Home-based, Computerized Cognitive Training Program in Pediatric Sickle Cell Disease

Anemia, Sickle Cell

United States
Mathys Ltd Bettlach

Unknown

Clinical Study With the RM Pressfit Vitamys Cup in Combination With a Mathys Stem

Hip Replacement | Arthropathy of Hip
Motus Therapeutics, Inc.

Completed

Phase 2 Study to Evaluate Safety and Efficacy of RM-131 Administered to Patients With Chronic Constipation

Constipation

United States
Motus Therapeutics, Inc.

Completed

Phase 2 Study to Evaluate Safety & Efficacy of RM-131 Administered to Patients With Diabetic Gastroparesis

Diabetes Mellitus | Gastroparesis | Diabetes Mellitus Complications

United States
University Hospital, Basel, Switzerland

Recruiting

Clinical Study With the seleXys PC and the RM Pressfit Vitamys Cup

Hip Joint | Arthritis, Degenerative

Switzerland
Motus Therapeutics, Inc.

Completed

Phase 2 Pilot Study to Evaluate the Safety and Efficacy of RM-131 Administered to Females With Anorexia Nervosa

Anorexia Nervosa

United States
Motus Therapeutics, Inc.

Completed

Study to Assess Pharmacodynamics of RM-131 in Patients With Diabetic Gastroparesis

Gastroparesis | Gastrointestinal Motility Disorder | Diabetes Mellitus Complications | Diabetes Mellitus Type 1 and 2

United States
Fundación para la Investigación del Hospital Clínico...

Unknown

OLA to Lowest DP in Cardiac Surgery

Lung Collapse

Spain
Motus Therapeutics, Inc.
Mayo Clinic

Completed

Effect of Relamorelin on Satiation, Gastric Volume, Gastric Accommodation and Distal Gastric Function in Healthy Volunteers

Gastric Motility

United States
Allergan

Completed

Safety and Efficacy of Relamorelin Administered to Participants With Vomiting Symptoms and Moderate to Severe Diabetic Gastroparesis

Diabetes Mellitus | Gastroparesis | Diabetes Mellitus Complications

United States, United Kingdom, Belgium, Israel, Germany, Poland, Sweden
RetMap, Inc
University of Illinois at Chicago; Illinois College of Optometry

Active, not recruiting

Evaluating a New Sensor That Measures the Health of the Retina in Normally-sighted Subjects

Electrode Site Reaction

United States
Alexandria University

Completed

Effects of Alveolar Recruitment Strategies on Arterial Oxygenation and Postoperative Inflammatory Response During Laparoscopic Bariatric Surgery: A Randomised Control Trial.

Bariatric Surgery Candidate

Egypt
University of Miami

Completed

Use of RM Technology in Pediatric BAI Recipients

Hearing Loss, Unilateral

United States
Motus Therapeutics, Inc.
Michael J. Fox Foundation for Parkinson's Research

Terminated

A Phase 2 Study to Evaluate the Safety and Efficacy of RM-131 in Patients With Parkinson's Disease & Chronic Constipation (MOVE-PD)

Parkinson's Disease

United States
Aarhus University Hospital

Unknown

Paediatric Early Warning System - A Danish Multi-center Study

Paediatric Early Warning System

Denmark
BNM Clinic and Research

Completed

10 Years Evaluation of Composite Restoration

Dental Restoration, Permanent
Mansoura University

Completed

High Versus Low Positive End Expiratory Pressure With Alveolar Recruitment Maneuver in Laparoscopic Bariatric Surgeries

Anesthesia

Egypt
Infinity Pharmaceuticals, Inc.

Terminated

A Phase 1 Dose Escalation Study of IPI-493

Advanced Malignancies

United States
Mansoura University

Completed

Effects of Two Different Stepwise Lung Recruitment Maneuvers on Patient Hemodynamics During Laproscopic Surgery

Recruitment

Egypt
Five Eleven Pharma, Inc.
Indiana University

Active, not recruiting

Biodistribution and Dosimetry of Ga-68 P16-093 in Prostate Cancer

Prostate Cancer | Prostate Cancer Recurrent

United States
G.R. Dome Medical Ltd.

Unknown

Pre-Marketing Feasibility Evaluation of the UriCap-RM - Urine Collection in Hospitalized Male Patients

Urinary Incontinence
Research Institute for Complex Problems of Cardiovascular...

Recruiting

Impact of the CareLink Express Remote Monitoring System on Early Detection of Atrial Fibrillation

Atrial Fibrillation

Russian Federation
Cambridge Glycoscience

Completed

A Study Assessing the Tolerable Upper Intake Level and Safety of Sugars From Fiber

Gastrointestinal Tolerance

Ireland
AbbVie

Completed

Pharmacokinetics and Safety of ABT-493 and/or ABT-530 in Subjects With Normal and Impaired Hepatic Function

Hepatic Impairment

United States, New Zealand
AbbVie

Completed

Pharmacokinetics and Safety of ABT-493 and ABT-530 in Subjects With Normal and Impaired Renal Function

Renal Impairment

United States, New Zealand
Taipei Medical University Shuang Ho Hospital
Taipei Medical University WanFang Hospital; Tri-Service General Hospital; Asian...

Not yet recruiting

Comparison Between Robotic (RM) and Laparoscopic Myomectomy (LM)

Surgical Procedure, Unspecified | Uterine Leiomyoma

Taiwan
AbbVie

Completed

A Study to Evaluate the Efficacy and Safety of ABT-493/ABT-530 in Renally Impaired Adults With Chronic Hepatitis C Virus Genotype 1 - 6 Infection (EXPEDITION-4)

Chronic Hepatitis C Virus (HCV) Infection
University of Miami
Cochlear

Completed

Remote Microphone (RM) - A Comparative Study

Hearing Loss, Conductive

United States
Motus Therapeutics, Inc.
Mayo Clinic

Completed

Study to Evaluate the Effects of RM-131 in Patients With Chronic Constipation

Chronic Constipation

United States
AbbVie

Completed

The Efficacy and Safety of ABT-493/ABT-530 in Adults With Chronic Hepatitis C Virus Genotype 4, 5, or 6 Infection (ENDURANCE-4) (ENDURANCE-4)

Hepatitis C Virus
AbbVie

Completed

A Study of Glecaprevir (GLE)/Pibrentasvir (PIB) in Treatment-Naive Adults With Chronic Hepatitis C Virus (HCV) Genotype 1-6 Infection and Compensated Cirrhosis (EXPEDITION-8)

Hepatitis C Virus (HCV)

United States, Bulgaria, Canada, Czechia, France, Greece, Hungary, Ireland, Israel, Italy, Poland, Portugal, Puerto Rico, Romania, Russian Federation, Spain, Taiwan, United Kingdom, Vietnam
AbbVie

Approved for marketing

Expanded Access to Glecaprevir/ Pibrentasvir

Hepatitis C Virus Infection

Slovenia
Nottingham University Hospitals NHS Trust
National Institute for Health Research, United Kingdom

Completed

Evaluation of Cogmed Working Memory Training for Adult Hearing Aid Users (TEACH2)

Hearing Loss

United Kingdom

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