Search clinical trials for: saline solution (placebo)

Total 77018 results

Iacta Pharmaceuticals

Recruiting

A Study to Assess the Safety and Efficacy of IC265 Ophthalmic Solution for Dry Eye in Adult Participants

Dry Eye Syndromes

United States
Santen Pharmaceutical Co., Ltd.

Completed

Assessing Safety and Efficacy of DE-089 Ophthalmic Solution in Patients With Dry Eye Disease

Dry Eye Disease

Taiwan
Livionex Inc.

Completed

The Safety and Efficacy Study of Ethylenediaminetetraacetic Acid (EDTA) Ophthalmic Solution in Patients With Loss of Contrast Sensitivity Due to Age-Related, Low-Grade Nuclear Cataract

Age Related Cataracts

United States
The University of Queensland
Baxter Healthcare Corporation; Health Research Council, New Zealand; Australian...

Completed

Better Evidence for Selecting Transplant Fluids (BEST-Fluids)

End Stage Kidney Disease | Kidney Transplant; Complications | Delayed Graft Function

Australia, New Zealand
Santen Inc.

Completed

Study Assessing the Efficacy and Safety of STN1013600 Ophthalmic Solution 0.1% and 0.3% Compared With Placebo in Subjects With Presbyopia (OPSIS)

Presbyopia

United States
Pulmatrix Inc.

Completed

21 Day Cumulative Skin Irritation of RUT058-60

Irritation/Irritant

United States
GlaxoSmithKline

Completed

Immunogenicity and Safety Study of GSK Biologicals' Herpes Zoster Vaccine With Various Formulations in Adults >= 50 Years

Herpes Zoster

United States, Spain, Czechia
University of Alberta

Withdrawn

A Study to Systematically Assess the Efficacy and Safety of Intravenous Albumin Infusions in Severe POTS

Postural Orthostatic Tachycardia Syndrome
Hanlim Pharm. Co., Ltd.

Completed

A Clinical Trial to Evaluate Tolerability and Pharmacokinetics of HL217 Eye Drop in Healthy Male Subjects

Healthy Subject
Bayer

Completed

Study on the Safety of the Drug BAY2395840 at Different Doses, the Way the Body Absorbs, Distributes and Excretes the Drug Including the Effect of Its Formulation (Tablet or Liquid) and the Effect of Food on the Absorption, Distribution or Excretion of the Drug in Healthy Male Participants

Endometriosis

Germany
Mimetogen Pharmaceuticals USA, Inc.

Completed

Tavilermide Ophthalmic Solution for the Treatment of Dry Eye

Dry Eye | Keratoconjunctivitis Sicca

United States
Ohio State University

Recruiting

Supplemental Citicoline Administration to Reduce Lung Injury Efficacy Trial (SCARLET) (SCARLET)

COVID-19

United States
Fundación Pública Andaluza Progreso y Salud

Completed

Efficacy and Safety of Topical Application of Tranexamic Acid for Saving Blood Losses in Patients Subjected to Prosthetic Knee Surgery (TRA)

Osteoarthritis, Knee

Spain
Wright State University

Terminated

Aerosolized Antibiotics in the Treatment of Ventilator Associated Pneumonia (AAINTVAP)

Pneumonia, Ventilator-Associated

United States
Universitaire Ziekenhuizen KU Leuven

Unknown

The Effect of Liraglutide on the GIT (LIRHV)

Obesity
B. Braun Melsungen AG

Completed

Comparison of HES 130 in Balanced and in Unbalanced Solution

Decreased and Nonspecific Blood Pressure Disorders and Shock

China
Apeiron Biologics

Completed

Recombinant Human Angiotensin-converting Enzyme 2 (rhACE2) as a Treatment for Patients With COVID-19 (APN01-COVID-19)

COVID-19

Denmark, Germany, Austria, Russian Federation, United Kingdom
Seoul National University Bundang Hospital
SMG-SNU Boramae Medical Center

Terminated

Effect of Darbepoetin in Contrast-induced Nephropathy

Acute Kidney Injury

Korea, Republic of
University of British Columbia

Completed

Does the Rapid Intravenous Administration of Oxytocin After Delivery of the Baby Decrease the Bleeding During Cesarean Section in Women at Risk of Bleeding During Cesarean Section?

Postpartum Hemorrhage

Canada
The Methodist Hospital Research Institute

Recruiting

CBD for Pain Following Orthopedic Shoulder Surgery (CBD)

Rotator Cuff Injuries | Shoulder Osteoarthritis

United States
GlaxoSmithKline

Terminated

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Food Effect of Single or Repeat Doses of GSK2793660 in Healthy Subjects

Bronchiectasis

United Kingdom
WellSpan Health

Completed

Preoperative Antibiotics for Carpal Tunnel Release Surgery

Carpal Tunnel Syndrome

United States
Fundación FLS de Lucha Contra el Sida, las Enfermedades...
Germans Trias i Pujol Hospital; Grifols Biologicals, LLC; Banc de Sang i Teixits and other collaborators

Completed

Plasma for Early Treatment in Non-hospitalised Mild or Moderate COVID-19 Patients

SARS-CoV-2 Infection | Safety and Efficacy

Spain
Mario Negri Institute for Pharmacological Research

Completed

Somatostatin In Patients With Autosomal Dominant Polycystic Kidney Disease And Moderate To Severe Renal Insufficiency (ALADIN2)

Autosomal Dominant Polycystic Kidney Disease

Italy
Polyheal Ltd.

Unknown

Study to Evaluate Polyheal-1 in Treatment of Recalcitrant Wounds

Wounds and Injuries

Israel
GlaxoSmithKline

Completed

Phase1 Study of GR121167, Single and Multiple Dose Study in Healthy Japanese Males

Influenza, Human

Japan
G. d'Annunzio University

Completed

PrevenTion of Contrast-inducEd nephroAThy With urinE Alkalinization (TEATE)

Acute Kidney Injury | Contrast Media Reaction

Italy
Galsor S.r.l.

Completed

Sinuclean's Treatment Of Sinusitis' Symptoms (SToSS)

Sinusitis

Italy
EyePoint Pharmaceuticals, Inc.
Medical Technology Enterprise Consortium (MTEC)

Terminated

Evaluation of the Safety and Efficacy of Razuprotafib in Hospitalized Subjects With Coronavirus Disease 2019 (RESCUE)

COVID-19 | Acute Respiratory Distress Syndrome (ARDS)

United States
Allan Vestergaard Danielsen, MD

Not yet recruiting

Botulinum Toxin A as Treatment for Chronic Postsurgical Pain Following Lung Cancer Surgery

Pain, Postoperative | Chronic Pain | Pain, Neuropathic | Post-thoracotomy Pain Syndrome

Denmark
Global Health Drug Discovery Institute
CMAX Clinical Research Pty Limited; Avance Clinical

Completed

SAD Study of APR002 Investigating the Safety/Tolerability, Pharmacokinetics/Pharmacodynamics in Healthy Subjects

COVID-19

Australia
Second Affiliated Hospital, School of Medicine,...

Unknown

Intraoperative Small-dose Esketamine Infusion for Pain Control in Burn Patients

Burns

China
Valneva Austria GmbH

Completed

Confirmatory Phase II/III Study Assessing Efficacy, Immunogenicity and Safety of IC43

Pseudomonas Aeruginosa Infection

Spain, Germany, Belgium, Austria, Czech Republic, Hungary
Özlem Çağan

Completed

The Effect of Ylang Ylang Oil and Lemon Oil (Aromatherapy)

Anxiety | Aromatherapy | Pain, Labor

Turkey
Herantis Pharma Plc.
ORA, Inc.

Completed

Phase 2 Study With Cis-UCA Ophthalmic Solutions in Subjects With Dry Eye

Dry Eye Syndrome

United States
Institut d'Investigació Biomèdica de Girona Dr....
Germans Trias i Pujol Hospital; University Hospital of Girona Dr.Josep Trueta

Recruiting

Benefits of Inhalation of Hypertonic Saline Solution Prior to Physiotherapy ELTGOL Technique in Bronchiectasis

Bronchiectasis Adult

Spain
Legacy Healthcare SA

Completed

Efficacy, Safety and Tolerability of CG428 Cutaneous Solution on Chemotherapy Induced Alopecia; Controlled Study (ELAN) (ELAN)

Alopecia

Switzerland
Rigel Pharmaceuticals

Completed

A Safety, Tolerability and Pharmacokinetics Study of R932348 Eye Drops in Patients With Dry Eye Disease

Keratoconjunctivitis Sicca

United States
Tissue Tech Inc.

Not yet recruiting

TTAX03 for the Treatment of Lumbosacral Facet Joint Pain

Facet Joint Pain
Sewon Cellontech Co., Ltd.

Unknown

Efficacy of Intra-articular Collagen Injection in Patients With Knee Joint Pain Compared to Normal Saline Injection

Osteoarthritis | Traumatic Arthritis | Chondromalacia

Korea, Republic of
Santen Inc.

Completed

Multi-center Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution in Subjects With Primary Open-angle Glaucoma or Ocular Hypertension

Open-angle Glaucoma or Ocular Hypertension

United States
Milton S. Hershey Medical Center

Terminated

Clinical, Pharmacological and Molecular Effects of IV and Oral Acetaminophen in Adults With aSAH (aSAH)

Stroke | Subarachnoid Hemorrhage

United States
Stuart Therapeutics, Inc.
ORA, Inc.

Completed

Study of ST-100 as Treatment for Dry Eye Disease

Dry Eye Disease

United States
Rigel Pharmaceuticals

Completed

To Assess the Safety and Efficacy of R932348 Ophthalmic Solutions in Patients With Keratoconjunctivitis Sicca (DROPS)

Keratoconjunctivitis Sicca

United States
Boehringer Ingelheim

Completed

Safety and Tolerability of BI 638683 After Single Rising Oral Doses in Healthy Male Subjects

Healthy

Germany
The George Institute

Not yet recruiting

Balanced Multi-Electrolyte Solution Versus Saline Trial for Diabetic KetoAcidosis (BEST-DKA)

Diabetic Ketoacidosis

Australia
Boehringer Ingelheim

Completed

A Study in Healthy Men to Test How the Body Takes up and Tolerates Different Doses of BI 474121, and Whether it Makes a Difference if BI 474121 is Taken as a Tablet or a Drink.

Healthy

Germany
pH Pharma

Completed

Evaluation of PHP-201 Ophthalmic Solution in Patients With Normal Tension Glaucoma

Normal Tension Glaucoma

Korea, Republic of
Medical Center Alkmaar

Completed

Inhaled Nebulized Tobramycin in Non-cystic Fibrosis Bronchiectasis (BATTLE)

Non-CF Bronchiectasis

Netherlands
Sanofi Pasteur, a Sanofi Company

Completed

Safety and Immunogenicity of ChimeriVax-WN02 West Nile Vaccine in Healthy Adults

West Nile Fever

United States

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