Latest Trials

Total 2895 results

University of Oxford
Kinshasa School of Public Health

Completed

Neonatal Hyperbilirubinaemia in the Democratic Republic of Congo

Neonatal Hyperbilirubinemia

Congo, The Democratic Republic of the
Jhpiego
Bill and Melinda Gates Foundation

Completed

Effects of a Health Workforce Capacity Building and Quality Improvement Intervention in Kinshasa

Infant Death | Maternal Death | Stillbirth

Congo, The Democratic Republic of the
Drugs for Neglected Diseases

Completed

Efficacy and Safety of Fexinidazole in Patients With Stage 1 or Early Stage 2 Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open-label Cohort Study, plug-in to the Pivotal Study

Human African Trypanosomiasis (HAT)

Congo, The Democratic Republic of the
NICHD Global Network for Women's and Children's...
National Cancer Institute (NCI); National Institute of Dental and Craniofacial... and other collaborators

Completed

Study of Pharmacokinetics and Pharmacodynamics of Artesunate in Pregnant Women in the Democratic Republic of Congo

Malaria

Congo, The Democratic Republic of the
NICHD Global Network for Women's and Children's...
National Cancer Institute (NCI); National Institute of Dental and Craniofacial... and other collaborators

Completed

Safe Pregnancy by Infectious Disease Control

Pregnancy | Malaria

Congo, The Democratic Republic of the
University of North Carolina, Chapel Hill
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Bedside Improvement of Resuscitation Through mHealth Feedback (BIRTH Study)

Respiratory Depression Neonatal

Congo, The Democratic Republic of the
Michigan State University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Caregiver Training to Prevent Konzo Disease in Children in Democratic Republic of Congo (DRC)

Malnutrition | Manihot Species Poisoning

Congo, The Democratic Republic of the
Institut Pasteur
Institut National de Recherche Biomédicale. Kinshasa, République Démocratique... and other collaborators

Completed

Viral and Microbial Circulation Between Humans, Domesticated and Wild Animals Along an Ecotone, Democratic Republic of Congo (MICROTONE)

Zoonotic Disease

Congo, The Democratic Republic of the
University of Kinshasa
KU Leuven

Completed

Hydroxyurea Treatment for Adult Sickle Cell Anemia Patients in Kinshasa

Sickle-Cell Anaemia

Congo, The Democratic Republic of the
Johns Hopkins Bloomberg School of Public Health
Bill and Melinda Gates Foundation; Save the Children; Institute for Reproductive...

Completed

Global Early Adolescent Study - Kinshasa (GEAS_KI)

Reproductive Health | Gender Relations

Congo, The Democratic Republic of the
University of Kinshasa
Novartis; European and Developing Countries Clinical Trials Partnership (EDCTP)

Completed

Comparison of ISTp- PYRAMAX-US-RDT to IPTp-SP to Prevent Malaria in Pregnant Women in DRC (ULTRAPYRAPREG) (ULTRAPYRAPREG)

Malaria in Pregnancy

Congo, The Democratic Republic of the
Institute of Tropical Medicine, Belgium
KU Leuven; Institut National de Recherche Biomédicale. Kinshasa, République... and other collaborators

Completed

Health Itinerary of Young Children With Suspected Bloodstream Infection in Kisantu General Referral Hospital, DR Congo (HIT BSI)

Health Care Utilization | Bloodstream Infection | Febrile Illness | Malaria,Falciparum | Salmonella Infection Non-Typhoid

Congo, The Democratic Republic of the
University of Oxford
University of Kinshasa; Mahidol Oxford Tropical Medicine Research Unit

Completed

Lung Ultrasound in Children With Severe Malaria (LUSiSM)

Severe Malaria

Congo, The Democratic Republic of the
Ministry of Public Health, Democratic Republic...
National Institutes of Health (NIH); Oregon Health and Science University; National... and other collaborators

Completed

Cassava Intervention Project

Neurotoxicity Syndrome, Cassava | Neurotoxicity Syndrome, Cyanate | Neurotoxicity Syndrome, Cyanide | Neurotoxicity Syndrome, Thiocyanate

Congo, The Democratic Republic of the
American Academy of Pediatrics
University of North Carolina, Chapel Hill; Thrasher Research Fund; RTI International and other collaborators

Completed

Newborn Heart Rate as a Catalyst for Improved Survival

Stillbirth | Neonatal Resuscitation | Neonatal Respiratory Depression | Neonatal Bradycardia

Congo, The Democratic Republic of the
University of North Carolina, Chapel Hill
Burroughs Wellcome; The American Society of Tropical Medicine and Hygiene

Completed

Evaluating Immunogenicity of a Birth Dose of HBV Vaccine in the DRC

Hepatitis B

Congo, The Democratic Republic of the
University of North Carolina, Chapel Hill
Ohio State University; Kinshasa School of Public Health

Completed

Arresting Vertical Transmission of Hepatitis B Virus (AVERT-HBV)

Hepatitis B | Vertical Transmission of Infectious Disease

Congo, The Democratic Republic of the
Guyguy K Tshima, MD
Centre Médical de Kinshasa (CMK)

Unknown

COVID-19: Collecting Measurements of Renin-angiotensin-system Markers, Such as Angiotensin-2 and Angiotensin 1-7 (Tomeka)

Covid19

Congo, The Democratic Republic of the
MOA Health Science Foundation

Completed

Effectiveness of Laying-on-of-hands for Sickle Cell Disease

Anemia | Death | Sickle Cell Disease | Infection | Pain Crisis Recurrent

Congo, The Democratic Republic of the
University of California, San Francisco
National Eye Institute (NEI); Institut National de Recherche Biomédicale. Kinshasa...

Not yet recruiting

Azithromycin Reduction to Reach Elimination of Trachoma B (ARRET)

Trachoma

Congo, The Democratic Republic of the
Institute of Tropical Medicine, Belgium
University of Manitoba; National Institute of Allergy and Infectious Diseases... and other collaborators

Recruiting

Monkeypox, Biology, Outcome, Transmission and Epidemiology -Prospective Follow-up of High-risk Contacts (MBOTE-CONTACT)

Mpox

Congo, The Democratic Republic of the
National Institute of Allergy and Infectious Diseases...
Institut National de Recherche Biomédicale. Kinshasa, République Démocratique...

Recruiting

Tecovirimat for Treatment of Monkeypox Virus

Monkeypox

Congo, The Democratic Republic of the
University of British Columbia
Mahidol Oxford Tropical Medicine Research Unit; Kinshasa Medical Oxford Research...

Recruiting

Effect of Paracetamol on Kidney Function in Severe Malaria (PROTECtS)

Acute Kidney Injury | Malaria,Falciparum | Severe Malaria | Paracetamol

Congo, The Democratic Republic of the
Medicines Development for Global Health

Active, not recruiting

Safety and Efficacy of Annual or Biannual Doses of Moxidectin or Ivermectin for Onchocerciasis

Onchocerciasis

Congo, The Democratic Republic of the
World Bank
International Rescue Committee

Completed

Preventing Intimate-partner Violence: Impact Evaluation of Engaging Men Through Accountable Practice in Eastern DRC

Domestic Violence | Intimate Partner Violence | Family Relations

Congo, The Democratic Republic of the
University of North Carolina, Chapel Hill
Albert Einstein College of Medicine; Abbott; Doris Duke Charitable Foundation; Université...

Recruiting

The COMBAT HBV Feasibility Trial (COMBAT-HBV)

Hepatitis B | Vertical Transmission of Infectious Disease

Congo, The Democratic Republic of the
University of Oxford
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.; National Institute... and other collaborators

Completed

Study to Compare Feasibility of 1-step Injectable Artesunate vs. Conventional 2-step Injectable Artesunate (1STEP-AS)

Severe Malaria

Congo, The Democratic Republic of the
University of Oxford
Kinshasa School of Public Health; Wellcome Sanger Institute

Completed

Monitoring Pregnant Women for Antimalarial Drug Resistance (MIRANDA)

Malaria

Congo, The Democratic Republic of the
Institute of Tropical Medicine, Belgium
Institut National de Recherche Biomédicale. Kinshasa, République Démocratique...

Completed

COVID-19 Sero-prevalence Health Care Workers Kinshasa (PRESTACOV)

SARS-CoV Infection | Seroprevalence

Congo, The Democratic Republic of the
Institute of Tropical Medicine, Belgium
Institut National de Recherche Biomédicale. Kinshasa, République Démocratique... and other collaborators

Completed

Transmission Dynamics of COVID-19 in a Rural Setting of the Democratic Republic of the Congo (DynaCovid)

Covid19

Congo, The Democratic Republic of the
Institute of Tropical Medicine, Belgium
KU Leuven; Institut National de Recherche Biomédicale. Kinshasa, République... and other collaborators

Completed

Treating Non-typhoidal Salmonella Bloodstream Infections in Children Under Five in DR Congo: a Cohort Study (TreNTS)

Blood-stream Infections | Salmonella Infection Non-Typhoid

Congo, The Democratic Republic of the
Albert Einstein College of Medicine
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Long Term Outcomes of Therapy in Women Initiated on Lifelong ART Because of Pregnancy in DR Congo (CQI-PMTCT)

HIV/AIDS | Antiretroviral Therapy | Pregnancy Outcomes | HIV-exposed Infants

Congo, The Democratic Republic of the
London School of Hygiene and Tropical Medicine
Public Health England; Janssen Vaccines & Prevention B.V.; Epicentre; Coalition... and other collaborators

Active, not recruiting

Effectiveness and Safety of a Heterologous, Two-dose Ebola Vaccine in the DRC

Ebola Virus Disease

Congo, The Democratic Republic of the
Drugs for Neglected Diseases

Completed

Efficacy and Safety of Fexinidazole in Children at Least 6 Years Old and Weighing Over 20 kg With Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open Study, plug-in to the Pivotal Study

Human African Trypanosomiasis (HAT)

Congo, The Democratic Republic of the
University of Kinshasa
University Ghent; Université de Montréal

Unknown

COVID-19 Lessons Learned: the Outcome of TOMEKA® Project is to Teach (MD)

COVID-19

Congo, The Democratic Republic of the
Institute of Tropical Medicine, Belgium
Institut National de Recherche Biomédicale. Kinshasa, République Démocratique... and other collaborators

Completed

Causes of Acute Undifferentiated Fever in Outpatients in the Democratic Republic of Congo (RESFANDI)

Undifferentiated Acute Fever

Congo, The Democratic Republic of the
University of Oxford
Kinshasa School of Public Health

Completed

Bio-availability of Rectal Artesunate in Children With Severe Falciparum Malaria (REACH)

Malaria

Congo, The Democratic Republic of the
University of Oxford
Kinshasa School of Public Health

Completed

Parenteral Artesunate Compared to Quinine as a Cause of Late Anaemia in African Children With Malaria (DHART)

Anaemia

Congo, The Democratic Republic of the
Alliance for International Medical Action
Ministry of Public Health, Democratic Republic of the Congo; University of... and other collaborators

Completed

Optimizing Acute Malnutrition Management in Children Aged 6 to 59 Months in Democratic Republic of Congo (OptiMA-DRC)

Moderate Acute Malnutrition | Severe Acute Malnutrition | Randomized Clinical Trial | Child Malnutrition | Africa | Acute Malnutrition | Congo, The Democratic Republic of the

Congo, The Democratic Republic of the
Universiteit Antwerpen
European Research Council

Completed

Ivermectin Treatment of Persons With Onchocerciasis-associated Epilepsy (OAETREATe)

Epilepsy

Congo, The Democratic Republic of the
Robert Colebunders

Completed

Ivermectin Treatment in Patients With Onchocerciasis-associated Epilepsy (OAETREAT)

Epilepsy | Onchocerciasis | Ivermectin

Congo, The Democratic Republic of the
Johns Hopkins Bloomberg School of Public Health
Centers for Disease Control and Prevention; International Rescue Committee; University...

Completed

Non-inferiority Trial of Conditional vs Universal Follow up for Children With Fever in Democratic Republic of Congo

Fever

Congo, The Democratic Republic of the
Epicentre
Medecins Sans Frontieres, Spain

Completed

Efficacy Study of Amodiaquine-Artesunate and Artemether-Lumefantrine for the Treatment of Uncomplicated Malaria

Malaria, Falciparum

Congo, The Democratic Republic of the
London School of Hygiene and Tropical Medicine

Completed

Impact Evaluation of Urban Water Supply Improvements on Cholera and Other Diarrhoeal Diseases in Uvira, Democratic Republic of Congo

Diarrhea | Cholera

Congo, The Democratic Republic of the
Worcester Polytechnic Institute
Plesion International, Coatesville, PA; HEAL Africa Hospital, Goma, Democratic... and other collaborators

Withdrawn

Dried Leaf Artemisia (DLA) Compared to Artemisinin Combination Therapy (ACT) vs Malaria

Malaria

Congo, The Democratic Republic of the
Alliance for International Medical Action

Completed

Observational Study of the Clinico-biological Evolution and Standard of Care Offered to Patients With Ebola Virus Disease (EVISTA)

Ebola Virus Disease

Congo, The Democratic Republic of the
Institute of Tropical Medicine, Belgium
KU Leuven; Université de Kisangani

Completed

Reservoir of Invasive Salmonellosis in Children, DRC

Salmonella Infections | Infection of Bloodstream

Congo, The Democratic Republic of the
Institute of Tropical Medicine, Belgium

Recruiting

Surveillance of Vaccine-induced Immunity Against Ebola in Previously Vaccinated Health Care Workers (EBOSURV)

Immune Response

Congo, The Democratic Republic of the
Centers for Disease Control and Prevention
Bavarian Nordic; Kinshasa School of Public Health; Ministry of Public Health,...

Active, not recruiting

JYNNEOS Smallpox Vaccine in Adult Healthcare Personnel at Risk for Mpox in the Democratic Republic of the Congo

Monkeypox Virus Infection

Congo, The Democratic Republic of the
World Bank
Vivo international e.V.; Fonds Social de la République Démocratique du Congo

Completed

Psychosocial and Economic Impacts of Narrative Exposure Therapy for Violence Survivors in Eastern DRC

PTSD | Mental Health Disorder | Depression Anxiety Disorder | Gender-based Violence

Congo, The Democratic Republic of the

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