Search clinical trials for: HPN

Total 178 results

CARE Pharma Shanghai Ltd.

Completed

Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of a Single Ascending Dose (SAD) of CAN106 Administered Intravenously (IV) in Healthy Subjects

PNH

Singapore
Fondation Lenval

Withdrawn

Decompressive Craniectomy for Severe Traumatic Brain Injury in Children With Refractory Intracranial Hypertension (RANDECPED)

Hypertension Intracranial

France
Alexion Pharmaceuticals

Completed

Dose-Escalation Study of ALXN1210 IV in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH)

PNH

Korea, Republic of, Australia
Fondation Lenval

Completed

Scoliosis Surgery - ST2R (Simultaneous Translation on Two Rods) (ST2R)

Scoliosis

France
Fondation Lenval

Completed

An Appraisal of Minimal Invasive Surgery for Thoracic Neurogenic Tumour (DIUOP)

Neurogenic Thoracic Tumors

France
Fondation Lenval

Completed

CoCo-20: a Longitudinal Follow-up Study of the French Paediatric Population During and After the Coronavirus Pandemic COVID-19 (CoCo-20)

Mental Health Disorder

France
Handok Inc.

Completed

A Retrospective Chart Review Study to Evaluate the Impact of Eculizumab in Korean PNH Patients

PNH

Korea, Republic of
Soligenix

Completed

FLASH [Fluorescent Light Activated Synthetic Hypericin] Clinical Study: Topical SGX301 (Synthetic Hypericin) for the Treatment of Cutaneous T-Cell Lymphoma (Mycosis Fungoides)

Cutaneous T-Cell Lymphoma

United States
Fresenius Kabi

Terminated

Quality of Care of Oncological Patients With HPN (VHPE-S)

Tumors and Home Parenteral Nutrition

Germany
Fondation Lenval

Withdrawn

Influence of Fatigue on the Walking Pattern in Cerebral Palsy Patients.

Cerebral Palsy

France
Fondation Lenval

Withdrawn

Parental Compliance After Telephone Triage Advice During and After Confinement During the COVID-19 Epidemic in France (COVIDTEL)

Covid19

France
Shire
Nycomed Germany GmbH

Completed

Open-Label Study of Teduglutide for Subjects With PN-Dependent Short Bowel Syndrome (SBS)

Short Bowel Syndrome

Spain, United States, Canada, France, Denmark, Poland, Germany, Italy, United Kingdom
Shire

Completed

A One-Year, Open-Label Study With Teduglutide for Subjects Who Completed Study CL0600-021 (STEPS3)

Short Bowel Syndrome

United States
Fondation Lenval

Completed

Characteristic and Evolution of an Atypical IgE-mediated Cow Milk Allergy Form With Hands and Feet Angio-oedema (IgE-CMA)

Milk Allergy
Fondation Lenval

Completed

Emergency Psychological Intervention With Children: Alex Storm (ALEX)

Psychological Trauma

France
Horizon Therapeutics, LLC

Terminated

Observational Study That Will Collect Information on Patients With Urea Cycle Disorders (UCDs) (THRIVE)

Urea Cycle Disorder

United States
Hepanova Inc.

Unknown

A Study to Evaluate the Safety and Tolerability of Single and Multiple Ascending Doses of HPN-01 in Healthy Subjects

Non-Alcoholic Steatohepatitis (NASH)

United States
Apellis Pharmaceuticals, Inc.

Completed

Pilot Study to Assess Safety, Preliminary Efficacy and Pharmacokinetics of S.C. Pegcetacoplan (APL-2) in PNH Subjects. (PADDOCK)

Paroxysmal Nocturnal Hemoglobinuria

Hong Kong, Thailand, New Zealand, Malaysia
Apellis Pharmaceuticals, Inc.

Completed

A Phase I Study to Assess the Safety of Pegcetacoplan (APL-2) as an Add-On to Standard of Care in Subjects With PNH

Paroxysmal Nocturnal Hemoglobinuria (PNH)

United States
Apellis Pharmaceuticals, Inc.

Completed

A Phase IIa Study to Assess the Safety, Efficacy, and Pharmacokinetics of Subcutaneously Administered Pegcetacoplan (APL-2) in Subjects With PNH

PNH

Serbia, Bulgaria
University of Kansas Medical Center
National Institute of Nursing Research (NINR)

Completed

Teen and Young Adult Connections for Support From Multidisciplinary Professionals & Peers

Malnutrition | Malabsorption | Short Bowel Syndrome

United States
AKARI Therapeutics

Completed

Treating Paroxysmal Nocturnal Haemoglobinuria Patients With rVA576 (CAPSTONE)

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Kazakhstan, Lithuania, Sri Lanka
Fondation Lenval

Completed

Intranasal Ketamine and Fracture Reduction in Pediatric Emergencies (KETAPED) (KETAPED)

Fractures, Closed

France
Fondation Lenval

Withdrawn

Incidence of Covid-19 in School Children (COVIDECOLE)

Infection; Viral, Coronavirus

France
Fondation Lenval

Completed

Emotional Information Processing in Attention Deficit Disorder With or Without Hyperactivity (TIVE-TDA)

Attention Deficit Disorder With Hyperactivity | Attention Deficit Disorder Without Hyperactivity

France
St. Jude Children's Research Hospital

Completed

Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Malignancies

Hodgkin Lymphoma | Myelodysplastic Syndrome (MDS) | Leukemia, Acute Lymphocytic (ALL) | Juvenile Myelomonocytic Leukemia (JMML) | Leukemia, Myeloid, Acute(AML) | Leukemia, Myeloid, Chronic(CML) | Hemoglobinuria, Paroxysmal Nocturnal (PNH) | Lymphoma, Non-Hodgkin (NHL)

United States
Alnylam Pharmaceuticals

Completed

A Phase 1/2 Study of an Investigational Drug, ALN-CC5, in Healthy Adult Volunteers and Patients With PNH

Paroxysmal Nocturnal Hemoglobinuria (PNH)

Spain, United Kingdom
Fondation Lenval

Completed

Smartphone Evaluation of Postoperative Pain Profiles Following General Surgery in Children (AlgoDARPEF)

Pain Measurement

France
Alexion Pharmaceuticals
CMIC Co, Ltd. Japan

Completed

E07-001: Safety and Efficacy Extension Study of Eculizumab in Paroxysmal Nocturnal Hemoglobinuria Patients

Paroxysmal Nocturnal Hemoglobinuria
Leslie Witton

Unknown

IMpact of Perineural Hydrodissection Over Alternative Therapies in Patients With Carpal Tunnel Syndrome (IMPACTS)

Carpal Tunnel Syndrome

Canada
Fondation Lenval

Completed

Using Nasal Broadband Glasses in the Initial Management of Severe Bronchiolitis in Infants Admitted in ICU (HFNC)

Bronchiolitis

France
Fondation Lenval

Completed

Feasability of Ambulatory Appendicectomy

Appendicitis Acute

France
Fondation Lenval

Completed

Single Time Management Diseases in Pediatric Traumatology

Fractures, Bone

France
Cyto Therapeutics Pty Limited

Unknown

A Study to Evaluate the Safety of Neural Stem Cells in Patients With Parkinson's Disease

Parkinson Disease

Australia
EssaiClinique_PL-HPN

Unknown

Effect of Depletive Lumbar Puncture on Lower Urinary Tract Dysfunction in iNPH (PLHPN)

Normal Pressure Hydrocephalus

France
Horizon Therapeutics, LLC

Completed

A Study of the Safety, Efficacy and Pharmacokinetics of Glycerol Phenylbutyrate in Pediatric Subjects Under 2 Years of Age With Urea Cycle Disorders

Urea Cycle Disorder

United States, Canada
Fondation Lenval

Completed

Pharmacogenetics Anomaly Research in Children and Adolescents With Pharmacological Resistance to Psychotropic Drugs (M4P)

Psychotropic Drugs | Drug Resistance

France
Alexion Pharmaceuticals

Completed

Eculizumab Pharmacokinetics/Pharmacodynamics Study in Pediatric/Adolescent Paroxysmal Nocturnal Hemoglobinuria (PNH)

Hemoglobinuria, Paroxysmal

United States
Fondation Lenval

Completed

What Care Pathways for Newborns Consulting Pediatric Emergencies? Prospective Study Over One Year (NNUP)

Emergencies

France
Fondation Lenval

Completed

Improving Social Cognition for Adults With ASD by the Serious Game JeStiMulE Versus Controls

Autistic Disorder

France
Fondation Lenval

Completed

Evaluation of Bladder Stimulation as a Noninvasive Technique of Urine Collection in Infant Who Have Not Acquired Walking (StiVeN)

Urinary Retention

France
Fondation Lenval

Completed

Recording Facial and Vocal Emotional Productions in Children With Autism as Part of the JEMImE Project

Autism | Pervasive Developmental Disorder

France
Fondation Lenval

Completed

Impact of the Choice of the Distal Vertebral in the Surgery of the Thoracic Adolescent Idiopathic Scoliosis (VD-SIA)

Scoliosis

France, Lebanon
Fondation Lenval

Completed

3 Dimensional Study of Lower Limbs and Feet of Children in Standing Position (MI3DEOS)

Limb Deformities

France
Fondation Lenval

Completed

The Physalis Child : Identification of Cognitive and Emotional Factors

Auditory Hallucinations

France
Fondation Lenval

Completed

Carbohydrate Counting in Children and Adolescents With Type 1 Diabetes

Type 1 Diabetes

France
Fondation Lenval

Completed

Bipolarity - Depression in Children and Adolescent Suicide Attempters: Better Diagnosis to Prevent Recurrence

Suicide, Attempted

France
Fondation Lenval

Completed

Obstructive Sleep Apnea and Down Syndrome: Clinical Examination Issue

Obstructive Sleep Apnea

France
Horizon Therapeutics, LLC

Completed

To Evaluate the Safety of Long-term Use of HPN-100 in the Management of Urea Cycle Disorders (UCDs)

Urea Cycle Disorders

United States, Canada
Alexion Pharmaceuticals

Completed

Safety and Efficacy Study of Eculizumab in Paroxysmal Nocturnal Hemoglobinuria Patients

Paroxysmal Nocturnal Hemoglobinuria

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