Clinical Trials Sponsored by JOTEC GmbH

Total 3292 results

Merck KGaA, Darmstadt, Germany
Merck Gesellschaft mbH, Austria

Completed

To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in Austria (ECOS AUT)

Growth Disorders

Austria
Gesellschaft fur Medizinische Innovation - Hamatologie...

Completed

Lenalidomide/Low-dose Dexamethasone in Combination With Continuous Oral Cyclophosphamide Compared to Lenalidomide/Low-dose Dexamethasone Combined With Single Cyclophosphamide Doses IV in Patients With Relapsed/Refractory Multiple Myeloma (MM_LEN_DEX_CY)

Multiple Myeloma

Germany
Medical University of Graz
Joanneum Research Forschungsgesellschaft mbH

Completed

Bioequivalence of Topical Acyclovir in Healthy Volunteers (FDA_BE1)

Dermatologic Disorders

Austria
Medical University of Graz
Joanneum Research Forschungsgesellschaft mbH

Completed

Investigating the Influence of Haemolysis on the Potassium Concentration After Capillary Blood Sampling

Hemolysis
Medical University of Graz
Joanneum Research Forschungsgesellschaft mbH

Completed

Lipofilling: Optimal Harvesting Techniques for Breast Reconstruction After Mastectomy in Plastic Aesthetic and Reconstructive Surgery (LipoTech)

The Impact of Adipose Tissue Quality on Fat Graft Retention

Austria
University of Michigan
DMG Dental Material Gesellschaft mbH

Completed

Resin Infiltration to Arrest Early Tooth Decay

Dental Caries

United States
Gesellschaft fur Medizinische Innovation - Hamatologie...

Completed

Comparison of 25mg Versus 5 mg Lenalidomide as Maintenance Therapy in Patients With Multiple Myeloma

Multiple Myeloma

Germany
Merck KGaA, Darmstadt, Germany
Gesellschaft für Therapieforschung mbH

Completed

An Observational Study Evaluating Therapy Optimisation Using High-frequency and High-dosage Administration of Interferon-beta (Rebif®) in Multiple Sclerosis (MS) Patients

Relapsing-Remitting Multiple Sclerosis
Merck KGaA, Darmstadt, Germany
Gesellschaft für Therapieforschung mbH

Completed

An Observational Study to Document the Effectiveness and Compatibility of Rebif 44 or 22 µg in the Therapy of the Chronic Multiple Sclerosis

Multiple Sclerosis

Germany
FH Joanneum Gesellschaft mbH
Austrian Research Promotion Agency

Recruiting

Validation Study SCOBES-AR

Cognitive Impairment | Cognitive Decline | Cognitive Deficit

Austria
Gesellschaft fur Medizinische Innovation - Hamatologie...

Terminated

Patients With Relapsed Ovarian Cancer (2nd and 3rd Line) Treated With Chemotherapy According to AGO Guidelines (TRACEII)

Ovarian Cancer

Germany
University of Michigan
DMG Dental Material Gesellschaft mbH

Completed

Radiographic Progression of Infiltrated Caries Lesions In-vivo (ICON)

Dental Caries

United States
Merck KGaA, Darmstadt, Germany
Merck Gesellschaft mbH, Austria

Completed

Bisoprolol in Hypertension: Effect on Concomitant Elevated Heart Rate

Hypertension

Austria
Merck KGaA, Darmstadt, Germany
Gesellschaft für Therapieforschung mbH

Completed

A Phase IV Study of Rebif ® 44mcg Administered Three Times Per Week by Subcutaneous Injection Compared With no Treatment in the Therapy of Relapsing Multiple Sclerosis After Mitoxantrone (REMAIN)

Multiple Sclerosis, Relapsing-Remitting
Christian Buske
Hoffmann-La Roche; Johnson & Johnson; ClinAssess GmbH; University of Ulm; Zentrum...

Active, not recruiting

Efficacy of First Line B-RI for Treatment Naive Waldenström's Macroglobulinemia

Waldenstrom Macroglobulinemia

Germany, Greece
Universitätsklinikum Hamburg-Eppendorf
Charite University, Berlin, Germany; University Hospital Ulm; University Medical...

Active, not recruiting

Comparative Effectiveness Trial of Transoral Head and Neck Surgery Followed by Adjuvant Radio(Chemo)Therapy Versus Primary Radiochemotherapy for Oropharyngeal Cancer

Oropharyngeal Cancer

Germany
HiPP GmbH & Co. Vertrieb KG
University Multiprofile Hospital for Active Treatment Dr. Georgi Stranski...

Active, not recruiting

Effect of an Infant Formula With Synbiotics in Infants Born Via Caesarean Section (GOLF-CS)

Gut Microbiota

Bulgaria
Prof. Dr. Wolfgang Hiddemann
Hoffmann-La Roche; Mundipharma Research GmbH & Co KG

Completed

First Line Therapy of Advanced Stage Follicular Lymphoma in Patients < 60 Years Not Eligible fo Standard Immunochemotherapy and in All Patients ≥ 60 Years (GABe2016)

Indolent Non-hodgkin Lymphoma

Germany
Institut fur Diabetes Karlsburg GmbH
Tyson Bioresearch Inc., Kedong 3rd Rd., Zhunan Township, Miaoli County 35053...

Completed

System Accuracy of the Blood Glucose Monitor for Personal Use JT100

Diabetes Mellitus

Germany
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Completed

Treosulfan and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Nonmalignant Inherited Disorders

Non-Neoplastic Hematologic and Lymphocytic Disorder

United States
Institut Cancerologie de l'Ouest
Poitiers University Hospital; IASON Gmbh, Feldkirchner strasse 4, 8054 Graz-Seiesberg... and other collaborators

Completed

Evaluation of Hypoxia by PET With F-Miso in Radiation Therapy of Prostate Cancer (HYPOXProstat)

Prostate Adenocarcinoma

France
Imperial College London
Nottingham University Hospitals NHS Trust; Royal Brompton & Harefield NHS Foundation... and other collaborators

Not yet recruiting

Nebulised Hypertonic Saline to Decrease Respiratory Exacerbations in Neuromuscular Disease or Neurodisability (SPICE-UP)

Cerebral Palsy | Neuromuscular Diseases | Neurodevelopmental Disorders

United Kingdom
Buchinger Wilhelmi Development & Holding GmbH
King's College London; Buchinger Wilhelmi Clinic; MVZ Labor Ravensburg GbR; Synlab...

Recruiting

Fastreset Study: Metabolic Effects of a Five-day Remotely Delivered Hypocaloric and Ketogenic Program (Fastreset)

Healthy Lifestyle | Healthy Nutrition

Germany
Georg Nilius, Prof DR med
Heinen und Löwenstein GmbH & Co. KG

Recruiting

Efficacy of Telemetry-assisted Care in Home Home Vented COPD (TeleInterVENT)

Chronic Obstructive Pulmonary Disease

Germany
University Medical Center Goettingen
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK); University Medical Center... and other collaborators

Recruiting

Safety and Efficacy of Induced Pluripotent Stem Cell-derived Engineered Human Myocardium as Biological Ventricular Assist Tissue in Terminal Heart Failure (BioVAT-HF)

Heart Failure

Germany
University of Wisconsin, Madison
Bristol-Myers Squibb; National Cancer Institute (NCI); AnYxis Immuno-Oncology... and other collaborators

Suspended

IT-hu14.18-IL2 With Radiation, Nivolumab and Ipilimumab for Melanoma

Melanoma

United States
Institut fur Diabetes Karlsburg GmbH
Tyson Bioresearch Inc., Kedong 3rd Rd., Zhunan Township, Miaoli County 35053...

Completed

Hematocrit Effect on a Blood Glucose Monitor

Diabetes Mellitus

Germany
University of Erlangen-Nürnberg Medical School
Merck Sharp & Dohme LLC; Rush University Medical Center; HELIOS Kliniken GmbH

Terminated

Modulation of the Surgical Inflammatory Response by Etoricoxib

Pain | Postoperative Pain | Osteoarthritis, Hip

Germany
Swiss Federal Institute of Technology
University of Zurich; University of Southampton; AIT Austrian Institute of Technology...

Completed

Vestibular Stimulation Therapy for Rhythmic Movement Disorder

Sleep Related Rhythmic Movement Disorder (Disorder)

Switzerland
Universitätsklinikum Hamburg-Eppendorf
Bristol-Myers Squibb; Eli Lilly and Company; UCB Pharma; Merck Sharp & Dohme LLC; AbbVi... and other collaborators

Recruiting

PsoBest - The German Psoriasis Registry

Psoriasis | Psoriatic-arthritis

Germany
Charite University, Berlin, Germany
German Research Foundation; European Union; The Volkswagen Foundation; Berlin Firebrigade and other collaborators

Completed

PHANTOM-S: The Pre-Hospital Acute Neurological Therapy and Optimization of Medical Care in Stroke Patients - Study (PHANTOM-S)

Acute Stroke

Germany
Evangelisches Krankenhaus Lutherhaus gGmbH
German Federal Ministry of Education and Research

Terminated

Comparison of the Effect of an Ongoing Treatment With Alendronate or a Drug Holiday on the Fracture Risk in Osteoporotic Patients With Bisphosphonate Long Term Therapy (BILANZ)

Osteoporosis

Germany
Peter Putz
NOUS Wissensmanagement GmbH; Johanniter Österreich Ausbildung und Forschung... and other collaborators

Completed

Digital Support for Quality Assurance in 24-hour Caregiving at Home (24h-quAALity)

Age Problem

Austria
University Hospital Muenster
Isotope Technologies Munich (ITM) Oncologics; Helmholtz Zentrum München Deutsches...

Recruiting

Radioimmunotherapy With Lu-177 Labeled 6A10 Fab-fragments in Patients With Glioblastoma After Standard Treatment (RIT in GBM)

Glioblastom WHO Grade 4

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Johann Wolfgang Goethe University Hospital, Prof. Dr. med. Trojan

Active, not recruiting

Dose Escalation Study of Cabozantinib for Advanced HCC Patients With Preserved Liver Function

Hepatocellular Carcinoma (HCC) | Second Line Treatment

Germany
Baxalta now part of Shire
Takeda Development Center Americas, Inc.; Baxalta Innovations GmbH, now part...

Active, not recruiting

A Study of BAX 888 in Male Adults With Severe Hemophilia A

Hemophilia A

United States, Spain, Hungary, Italy, Germany, Austria, France
Jena University Hospital
University of Leipzig; Technische Universität Dresden; University of Magdeburg; University of Rostock and other collaborators

Completed

Regional Differences in Human Immunodeficiency Virus (HIV) Testing (HIVRegional)

HIV Seropositivity | CD4+ T Lymphocytopenia

Germany
Pascoe Pharmazeutische Praeparate GmbH
Institut für Empirische Gesundheitsökonomie, Prof. Dr. Dr.med. Reinhard Rychlik...

Completed

Treatment of Patients Suffering From Nervous Restlessness With PASCOFLAIR®

Nervous Restlessness
AIO-Studien-gGmbH
Sanofi; Institut für Klinisch-Onkologische Forschung (IKF) Frankfurt

Completed

mFOLFOX6 vs. mFOLFOX6 + Aflibercept as Neoadjuvant Treatment in MRI-defined T3-rectal Cancer

Rectal Cancer | Rectosigmoid Cancer

Germany
ppharmaand GmbH
Bristol-Myers Squibb; Gynecologic Oncology Group; European Network of Gynaecological... and other collaborators

Active, not recruiting

A Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy (ATHENA)

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal | Newly Diagnosed | FIGO Stage III-IV | Partial Response | Complete Response

United States, United Kingdom, Korea, Republic of, Russian Federation, Canada, Denmark, Taiwan, New Zealand, Ireland, Japan, Spain, Australia, Israel, Italy, Greece, Sweden, Czechia, Finland, Poland, Belgium, Germany, Romania, Singa... and more
A. Vogel AG
CONVEX CRO; d.s.h. statistical services GmbH; MediStat Ltd.; Biodome Clinical; Bo... and other collaborators

Completed

Echinaforce Study to Investigate Explorative Pharmacology and Effectiveness to Prevent From Enveloped Virus Infections

Respiratory Tract Infections | Common Cold

Bulgaria
Heidelberg University
PD Dr. Henrik Watz, Pulmonary Research Center, LungenClinic Großhansdorf... and other collaborators

Active, not recruiting

Change in Airway Peripheral Tone in COPD (CAPTO-COPD)

COPD | COPD, Early-Onset

Germany
R.J. Reynolds Tobacco Company
University of Louisville; Covance; Analytisch-biologisches Forschungslabor GmbH; Arista Laboratories and other collaborators

Completed

Switching From Usual Brand Cigarettes to a Tobacco-heating Cigarette or Snus (QoL)

Cigarette Smoking

United States
University of Cambridge
Medical University of Graz; Cambridge University Hospitals NHS Foundation Trust and other collaborators

Completed

Short Term Closed-loop Glucose Control in Adults With Type 1 Diabetes (AP@home02)

Type 1 Diabetes

United Kingdom, Germany, Austria
Medical University Innsbruck
Charite University, Berlin, Germany; University Hospital, Ghent; University of... and other collaborators

Completed

Histidine-Tryptophane-Ketoglutarate (HTK) vs University of Wisconsin (UW) Perfusion in Clinical Pancreas Transplantation

Diabetes Mellitus | Pancreas Transplantation

Austria, Belgium, Germany
University Hospital Tuebingen
NIRX Medizintechnik GmbH, Gustav-Meyer Allee 25, 13355 Berlin; Hetzler Stiftung...

Recruiting

Influence of tDCS on the Brain Activation Measured During the Decision Not to Smoke in High-risk Situations

Tobacco Use Disorder

Germany
Deutsches Herzzentrum Muenchen
Abbott; EvidentIQ Germany GmbH; Institute of AI and Informatics in Medicine Technical...

Recruiting

Intracoronary Stenting and Restenosis - Randomized Trial of Drug-eluting Stent Implantation or Drug-coated Balloon Angioplasty According to Neointima Morphology in Drug-eluting Stent Restenosis 5 (ISAR-DESIRE5)

Coronary Artery Disease | Restenoses, Coronary

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Celgene International II S.á.r.l.; Prof. F. Heidel, MH Hannover

Recruiting

Fedratinib in Combination With Nivolumab

Primary Myelofibrosis | Secondary Myelofibrosis

Germany
Saving Patients' Lives Medical B.V.
Radboud University Medical Center; ABX-CRO advanced pharmaceutical services... and other collaborators

Recruiting

Ferumoxtran-10-enhanced MRI in Prostate Cancer Patients

Prostate Cancer | Metastasis | Prostatectomy

Germany, Belgium, Netherlands, Switzerland
Insel Gruppe AG, University Hospital Bern
Swiss National Science Foundation; Mach Gaensslen Foundation; Baxalta Innovations...

Recruiting

Genotype and Phenotype Correlation in Hereditary Thrombotic Thrombocytopenic Purpura (Upshaw-Schulman Syndrome) (TTP registry)

Thrombotic Thrombocytopenic Purpura | Congenital Thrombotic Thrombocytopenic Purpura | Familial Thrombotic Thrombocytopenic Purpura | Thrombotic Thrombocytopenic Purpura, Congenital | Upshaw-Schulman Syndrome

United States, Austria, Czechia, Germany, Japan, Norway, Switzerland

Clinical Trials Sponsored by JOTEC GmbH

Sponsors and Collaborators

Medical Conditions

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CROs in Sweden

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Rare Diseases

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