Clinical Trials Sponsored by Gates Foundation

Total 15862 results

Novavax
Bill and Melinda Gates Foundation

Completed

A Study Looking at the Effectiveness and Safety of a COVID-19 Vaccine in South African Adults

COVID-19 | SARS-CoV-2 Infection

South Africa
Jhpiego
Bill and Melinda Gates Foundation

Completed

Accelerating Newborn Survival in Ghana Through a Low-dose, High-frequency Health Worker Training Approach

Stillbirth | Neonatal Death
IDRI
Bill and Melinda Gates Foundation

Completed

Safety Study to Evaluate the Leish-111f + MPL-SE Vaccine in the Prevention of Cutaneous Leishmaniasis in Healthy Subjects Previously Exposed to the Leishmania Parasite

Cutaneous Leishmaniasis

Colombia
Jhpiego
Bill and Melinda Gates Foundation

Completed

Effects of a Health Workforce Capacity Building and Quality Improvement Intervention in Kinshasa

Infant Death | Maternal Death | Stillbirth

Congo, The Democratic Republic of the
Novavax
Bill and Melinda Gates Foundation

Completed

A Study to Determine the Safety and Efficacy of the RSV F Vaccine to Protect Infants Via Maternal Immunization

Respiratory Syncytial Virus Infections

United States, Argentina, Australia, Bangladesh, Chile, Mexico, New Zealand, Philippines, South Africa, Spain, United Kingdom
IDRI
Bill and Melinda Gates Foundation

Completed

Phase 1 LEISH-F3 + SLA-SE Vaccine Trial in Healthy Adult Volunteers

Visceral Leishmaniasis

United States
IDRI
Bill and Melinda Gates Foundation

Completed

Open-Label Safety Study of Three-Antigen Leishmania Polyprotein With Adjuvant MPL-SE in Healthy Adults in India

Visceral Leishmaniasis | Post-kala-azar Dermal Leishmaniasis

India
PATH
Bill and Melinda Gates Foundation

Withdrawn

Efficacy of iOWH032 in Dehydrating Cholera (POC)

Secretory Diarrhea

Bangladesh
PATH
Bill and Melinda Gates Foundation

Completed

Pilot Safety Study to Determine the Ability of the Protector Cap Jet Injector to Prevent Cross-Contamination

Virus Diseases | Hepatitis B
IDRI
Bill and Melinda Gates Foundation

Completed

Study to Evaluate the Leish-111F + MPL-SE Vaccine in the Treatment of Mucosal Leishmaniasis

Leishmaniasis, Mucocutaneous

Peru
IDRI
Bill and Melinda Gates Foundation

Completed

Study to Evaluate the Leish-111F + MPL-SE Vaccine in the Treatment of Cutaneous Leishmaniasis

Leishmaniasis, Cutaneous

Brazil
IDRI
Bill and Melinda Gates Foundation

Completed

Study to Evaluate the Leish-111f + MPL-SE Vaccine in Healthy Adults Not Previously Exposed to Leishmania Parasite

Cutaneous Leishmaniasis

Colombia
Ataulpho de Paiva Foundation
Bill and Melinda Gates Foundation

Completed

Xpert MTB/Rif, a New Tool for the Diagnosis of Pulmonary Tuberculosis in Two Municipalities in Brazil

Tuberculosis

Brazil
Population Council
Bill and Melinda Gates Foundation

Recruiting

Pilot Study on Engaging Family Physicians in Family Planning in Pakistan (FPFP)

Contraception | Contraceptive Usage

Pakistan
FHI 360
Bill and Melinda Gates Foundation

Recruiting

Casea S Contraceptive Implants (Casea S) Trial

Contraception

Dominican Republic
Fidec Corporation
Bill and Melinda Gates Foundation

Completed

A Study to Evaluate Immunogenicity of Intramuscular Full-Dose and Intradermal Fractional Dose of IPV

Poliomyelitis

Dominican Republic, Panama
Fidec Corporation
Bill and Melinda Gates Foundation

Completed

A Study to Evaluate Safety and Immunogenicity of tOPV in 1 to 5 Years and at 6 Weeks of Age (T2-ABMG)

Poliomyelitis
Fidec Corporation
Bill and Melinda Gates Foundation

Withdrawn

Evaluation of the Immunogenicity and Safety of Concomitant Administration of Novel Oral Polio Type 2 Vaccine and Bivalent Oral Polio Vaccine

Poliomyelitis
Fidec Corporation
Bill and Melinda Gates Foundation

Completed

A Study to Evaluate the Safety and Immunogenicity of Monovalent OPV2 in Children Aged 1 to 5 Years in Lithuania (M3-ABMG)

Poliomyelitis
FHI 360
Bill and Melinda Gates Foundation

Completed

Safety,Effectiveness and Acceptability of Sino-implant II in DR

Contraception

Dominican Republic
Boston University
Bill and Melinda Gates Foundation

Completed

Thermal Imaging of the Lung on a Smartphone to Differentiate Bacterial From Non Bacterial Causes of Pneumonia

Pneumonia, Bacterial | Infections, Bacterial

Malawi
Vaxtrials S.A.
Bill and Melinda Gates Foundation

Completed

Safety Study of a Single Dose of Monovalent High-dose Inactivated Poliovirus Type 2 Vaccine (m-IPV2 HD) in Infants Early in Life (IPV005)

Polio

Panama
Artann Laboratories
Bill and Melinda Gates Foundation

Completed

Clinical Evaluation of Ultrasonic Hydration Monitor for Infants (IHM-01)

Diarrhea | Dehydration

Latvia
Fidec Corporation
Bill and Melinda Gates Foundation

Active, not recruiting

A Study to Evaluate Pharyngeal Immunity to Poliovirus Type-2

Poliomyelitis

Bangladesh
Fidec Corporation
Bill and Melinda Gates Foundation

Completed

A Study to Evaluate the Safety and Immunogenicity of Novel Oral Polio Vaccine

Poliomyelitis

Panama
Stanford University
Bill and Melinda Gates Foundation

Completed

Team-Based Goals and Incentives for Community-Based Health Workers to Promote Maternal and Child Health in Bihar, India

Healthy
Certara
Bill and Melinda Gates Foundation; Parexel

Completed

International Registry of Healthcare Workers Exposed to COVID-19 Patients (UNITY Global) (UNITY Global)

Covid19 | SARS-CoV Infection

Pakistan
Makerere University
Bill and Melinda Gates Foundation

Active, not recruiting

Effect of Digital Payment to Campaign Health Workers on Vaccination Coverage

Polio

Uganda
Fidec Corporation
Bill and Melinda Gates Foundation

Withdrawn

A Study to Evaluate Immunogenicity of Various Schedules of Inactivated Polio Vaccine

Poliomyelitis
FHI 360
Bill and Melinda Gates Foundation

Completed

Contraceptive Effectiveness of Sino-implant (II) in China

Contraception

China
PATH
Bill and Melinda Gates Foundation; UNITAID

Recruiting

TIMCIs: A Hybrid Type 2 Study of Next-generation Pulse Oximeters

Focus of Study: Accurate Clinical Measurement and Diagnosis

Kenya
Tufts University
Bill and Melinda Gates Foundation

Recruiting

Safe and Effective Delivery of Supplemental Iron to Healthy Volunteers

Iron

United States
Yale University
Bill and Melinda Gates Foundation

Completed

Topical Antibacterial Agents for Prevention of COVID-19

COVID-19 | SARS-CoV2 Infection

United States
Stanford University
Bill and Melinda Gates Foundation

Completed

Use of Mobile Technology by Community-Based Health Workers to Promote Maternal and Child Health in Bihar, India (ICT-CCS)

Child | Pregnancy | Infant | Nutrition | Health
Fidec Corporation
Bill and Melinda Gates Foundation

Completed

Study to Evaluate Safety and Immunogenicity of nOPV2 at Different Intervals in Infants

Poliomyelitis

Dominican Republic
Fidec Corporation
Bill and Melinda Gates Foundation

Completed

A Study to Evaluate the Safety and Immunogenicity of Oral Polio Vaccine Type 2 in Infants and Children (M2-ABMG)

Adverse Event Following Immunisation
VaxInnate Corporation
Bill and Melinda Gates Foundation

Completed

Phase I Safety and Immunogenicity Study of VAX102 [Flagellin.HuM2e] Influenza Vaccine in Healthy Adults

Influenza Infection

United States
Makerere University
Bill and Melinda Gates Foundation

Completed

School Based Malaria Control in Ugandan Schoolchildren (SBMC)

Malaria

Uganda
Bill & Melinda Gates Medical Research Institute
Bill and Melinda Gates Foundation; Wellcome Trust

Recruiting

Study to Assess Efficacy and Safety of M72/AS01E-4 Mycobacterium Tuberculosis (Mtb) Vaccine in Adolescents and Adults

Tuberculosis

Indonesia, Kenya, South Africa, Vietnam, Malawi, Mozambique, Zambia
Elizabeth Glaser Pediatric AIDS Foundation
Bill and Melinda Gates Foundation

Active, not recruiting

Evaluation of Advanced HIV Disease Differentiated Care Model in Malawi

AIDS-related Kaposi Sarcoma | Cryptococcal Infections | AIDS and Infections | Opportunistic Infections, HIV-Related | AIDS With Tuberculosis

Malawi
Massachusetts General Hospital
Bill and Melinda Gates Foundation

Active, not recruiting

Pilot Study for Evaluation of Cryobiopsy and Correlation With Standard Forceps Biopsy

Gastrointestinal Disease

United States
University of Oxford
Bill and Melinda Gates Foundation

Completed

Effect of Ivermectin Metabolites on Mosquito Survival

Healthy

Thailand
Aga Khan University
Bill and Melinda Gates Foundation

Enrolling by invitation

Integrated Community Engagement and Audit Systems

Maternal Death | Stillbirth | Neonatal Death

Pakistan
Massachusetts General Hospital
Bill and Melinda Gates Foundation

Enrolling by invitation

Feasibility, Safety and Utility of Endomicroscopy to Study the Intestines of Unsedated Infants at University of Virginia (UVa)

Healthy

United States
Abbott Rapid Dx
Bill and Melinda Gates Foundation

Completed

Performance Evaluation of Malaria Plus Rapid Diagnostic Tests (RDTs) for the Detection of Plasmodium Infections in Patients With Symptoms Suggestive of Malaria

Malaria

Ethiopia
University of Washington
Bill and Melinda Gates Foundation

Completed

PrEP in Breastfeeding Study

HIV Pre-exposure Prophylaxis During Breastfeeding

Kenya, Uganda
University of Pittsburgh
Bill and Melinda Gates Foundation

Completed

Optimization of the ex Vivo Challenge: Reproductive Infections and Contraception

HIV

United States
University of Washington
Bill and Melinda Gates Foundation

Completed

Herpes Simplex Virus Type 2 (HSV-2) Suppression to Prevent HIV Transmission

HIV Infection | Sexually Transmitted Diseases | Herpes Simplex, Genital

South Africa, Kenya, Botswana, Rwanda, Tanzania, Uganda, Zambia
University of Pittsburgh
Bill and Melinda Gates Foundation

Completed

Vaginal Film Administration and Placement Study: FLAG (FLAG)

Healthy Women

United States
Johns Hopkins University
Bill and Melinda Gates Foundation

Completed

Modified Instrumentation for Surgery to Correct Trichiasis

Trachoma

United States

Clinical Trials Sponsored by Gates Foundation

Sponsors and Collaborators

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Drug Interventions

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CROs in Gambia

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Rare Diseases

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