Clinical Trials Sponsored by Goethe University

Total 220546 results

Johann Wolfgang Goethe University Hospital
Bethanien Krankenhaus gGmbH

Completed

Coronary Flow Rate Measurement in T-Grafts

Coronary Heart Disease

Germany
Goethe University
Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)

Completed

Validation of CMR Against Invasive Haemodynamics in Patients With HFpEF (DECIPHER-HFpEF)

Heart Failure With Normal Ejection Fraction

Germany
Dr. Patrick Meybohm, M.D.

Completed

The Role of Ninjurin-1 During Systemic Inflammation (Ninj1)

SIRS | Ninj1 Expression

Germany
Johann Wolfgang Goethe University Hospital

Unknown

Chemotherapy Via an Implantable Pump Compared With a Subcutaneous Port for Unresectable Liver Metastases in Patients With Resected Colorectal Cancer

Colorectal Cancer | Metastatic Cancer

Germany
Johann Wolfgang Goethe University Hospital

Unknown

Combination Chemotherapy in Treating Adults With Acute Lymphocytic Leukemia

Leukemia

Germany
Hubert Serve, Prof., MD

Unknown

Gene Therapy for X-CGD

X-linked Chronic Granulomatous Disease

Germany
Johann Wolfgang Goethe University Hospital
Allergopharma GmbH & Co. KG

Completed

Compatibility and Immunogenicity of a Short Specific Immunotherapy (SIT) in Contrast to Classic Specific Immunotherapy

Immunotherapy

Germany
Johann Wolfgang Goethe University Hospital
Ludwig-Maximilians - University of Munich

Completed

Non-invasive Diagnostics of Iron Deficiency in Surgical Patients by Measuring Zinc Protoporphyrin-IX

Iron-deficiency | Anemia | Iron Deficiency Anemia

Germany
PD Dr. Bertram Scheller
Goethe University; Dr. Franz Köhler Chemie GmbH (study medication and labeling)

Unknown

Evaluation if Physostigmine Reduces Symptoms in Patients Who Has Developed a Delirium in Intensive Care After a Surgery

Suspected Delirium After Elective or Emergency Heart Surgery | CAM-ICU Diagnosed Delirium

Germany
Goethe University
Society for Thrombosis and Haemostasis Research (Germany)

Recruiting

German Pediatric Hemophilia Research Database (GEPHARD)

Hemophilia A | Hemophilia B | Children | Drug Specific Antibodies

Germany
Johann Wolfgang Goethe University Hospital
B. Braun Melsungen AG

Unknown

Pilot Study to Asses the Function and Patency of Polyester-Coated Composite Bypasses From Autologous Varicose Veins (PROVENA)

Peripheral Arterial Disease | Peripheral Bypass Surgery | Bypass From Autologous Varicose Vein | External Graft Support

Germany
Johannes Vermehren
Klinikum Stadt Hanau

Unknown

Metal Stents (Moving Cell Stent) for Inoperable Tumors of the Bile Duct Tract

Bile Duct Cancer | Bile Duct Stricture

Germany
Medizinische Hochschule Brandenburg Theodor Fontane
Johann Wolfgang Goethe University Hospital

Completed

Maternal Microchimerism in Lymph Nodes of Infants With Biliary Atresia at Time of Kasai's Operation (K-LNMC)

Biliary Atresia

Germany
Johann Wolfgang Goethe University Hospital
Pfrimmer Nutricia GmbH, Erlangen , Germany

Completed

Peroral Supplemental Nutrition in End-stage Renal Disease With and Without HIV Comorbidity

End-Stage Renal Disease

Germany
Goethe University
Nationwide Network of University Medicine (NUM) on Covid-19

Recruiting

Intersectoral Platform (SÜP) of the National Pandemic Cohort Network (NAPKON) (SUEP-NAPKON)

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)

Germany
University of Erlangen-Nürnberg Medical School
Johann Wolfgang Goethe University Hospital

Recruiting

Investigation of the Clinical Efficacy of Low-dose Ionizing Radiation in the Treatment of Osteoarthritis (IMMO-LDRT02)

Osteoarthritis | Arthrosis

Germany
Johann Wolfgang Goethe University Hospital
Johannes Gutenberg University Mainz; Kerckhoff Klinik

Recruiting

International T1 Multicenter Outcome Study (T1Outcome-DE)

Coronary Artery Disease | Heart Failure | Chronic Kidney Diseases | Cardiomyopathies | Inflammatory Disease

Germany
Valentina Puentmann
Bayer; Alcedis GmbH

Recruiting

Myocardial Protection in Patients With Post-acute Inflammatory Cardiac Involvement Due to COVID-19 (MYOFLAME-19)

Microvascular Angina | Left Ventricular Dysfunction | Vascular Inflammation | Exercise Intolerance | Remodeling, Left Ventricle | Remodeling, Vascular | COVID-19 Associated Cardiac Involvement

Germany, Austria
University Heart Center Freiburg - Bad Krozingen
Johann Wolfgang Goethe University Hospital

Completed

Troponin T as Risk Stratification Tool in Peripheral Arterial Occlusive Disease

Peripheral Arterial Occlusive Disease

Germany
Goethe University
Maastricht University Medical Center; German Federal Ministry of Education... and other collaborators

Completed

Prioritising and Optimising Multi-medication in Multimorbidity (PRIMUM)

Chronic Disease

Germany
Christoph Königs
Roche Pharma AG; Chugai Pharma Germany GmbH

Recruiting

Dynamics of the Anti-factor VIII Antibody Signature During Treatment With Emicizumab (NAVIGATE)

Severe Hemophilia A | Severe Hemophilia A With Inhibitor | Severe Hemophilia A Without Inhibitor

Germany
University Hospital Inselspital, Berne
Charite University, Berlin, Germany; Goethe University; University of Basel

Completed

Copeptin for Risk Stratification in Acute Stroke Patients: the CoRisk Study (CoRisk)

Stroke | Transient Ischemic Attack

Germany, Switzerland
Wuerzburg University Hospital
Goethe University; University Hospital Munich; University Hospital Regensburg; University...

Completed

Enamel Caries in Orthodontic Patients (ECOP)

Dental Caries

Germany
Johann Wolfgang Goethe University Hospital
Medical University of Graz; University Hospital, Angers; Medical University of... and other collaborators

Completed

Preoperative Anaemia prevaLence In surgiCal patiEnts (ALICE)

Iron-deficiency | Anemia | Vitamin B 12 Deficiency | Folic Acid Deficiency | Anaemia of Renal Disease | Anemia of Chronic Inflammation

Germany
Gerd Geisslinger
Fraunhofer Institute for Molecular Biology and Applied Ecology

Completed

Bioavailability, Pharmacokinetics and Tissue Distribution of R-flurbiprofen Capsules in Healthy Subjects

Healthy Volunteers

Germany
Johann Wolfgang Goethe University Hospital
German Federal Ministry of Education and Research

Unknown

Gene Therapy for Chronic Granulomatous Disease (CGD)

Granulomatous Disease, Chronic

Germany
Johann Wolfgang Goethe University Hospital
Johannes Gutenberg University Mainz; University Hospital Ulm; Kerckhoff Klinik

Active, not recruiting

IMPRoving Cardiovascular RiSk Stratification Using T1 Mapping in General populatION (IMPReSSION)

Myocardial Fibrosis | Heart Failure | Myocarditis | Vascular Inflammation

Germany
Goethe University
King's College London; Radboud University Medical Center; Heidelberg University; Hospital Vall d'Hebron

Completed

Prevention of Comorbid Depression and Obesity in Attention-deficit/ Hyperactivity Disorder (PROUD)

Depression | Obesity | Attention-Deficit / Hyperactivity Disorder

Germany, Netherlands, Spain, United Kingdom
Nicolai Goettel

Completed

Standardization of a Novel Self-administered Tablet Computer-based Clinical Screening Tool for Adverse Postoperative Cognitive Outcomes (CogCheck-Norm)

Delirium

Switzerland
Nicolai Goettel

Completed

Comparison of Dexmedetomidine and Propofol-Remifentanil Conscious Sedation for Awake Craniotomy for Tumor Surgery

Brain Tumor

Canada
Nicolai Goettel
University Hospital, Basel, Switzerland

Completed

Cohort Study to Investigate the Association Between Changes in Brain Volume and Postoperative Cognitive Dysfunction (POCD-MRI)

Delirium | Dementia | Postoperative Cognitive Dysfunction

Switzerland
Johann Wolfgang Goethe University Hospital
Institut für Sportwissenschaften, Frankfurt; Fresenius University of Applied...

Completed

Physical Exercise Therapy in Pediatric Stem Cell Transplantation (BISON)

Hematopoetic Stem Cell Transplantation

Germany
Hannover Medical School
Goethe University; University Medicine Greifswald; University Hospital Schleswig-Holstein and other collaborators

Not yet recruiting

Personalized, Predictive, Precise & Preventive Medicine for Major Depression (P4D)

Major Depressive Disorder | Persistent Depressive Disorder
Nicolai Goettel

Recruiting

Development of a Prediction Model for Delirium After Cardiac Surgery Using a Novel Self-Administered Preoperative Cognitive Assessment Tool (CogCheck-Valid)

Cognitive Impairment | Cognition Disorders | Postoperative Delirium | Postoperative Cognitive Dysfunction | Cardiac Surgery | Cognitive Decline

Switzerland
Nicolai Goettel

Completed

Effect of Structured Patient Interviews in the Preoperative Anesthesia Clinic on Recall of Relevant Information (SPI-RECALL)

Communication | Anesthesia | Surgical Procedure, Unspecified

Switzerland
Fraunhofer Institute for Molecular Biology and...
Bristol-Myers Squibb; Goethe University

Completed

PREVALENCE OF Anti-CCP POSITIVITY AND SUBCLINICAL SIGNS OF INFLAMMATION IN PATIENTS WITH NEW ONSET OF NON-SPECIFIC MUSCULOSKELETAL SYMPTOMS (PANORA)

Rheumatoid Arthritis

Germany
Casey Goetz

Completed

The Use of Virtual Reality Goggles

Dental Anxiety

United States
Goethe University
German Federal Ministry of Education and Research; Deutsche Leukämie- & Lymphom-Hilfe

Recruiting

Randomized Trial in Adult de Novo Ph Positive ALL With Chemotherapy, Imatinib or Ponatinib, Blinatumomab and SCT (GMALL-EVOLVE)

Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Germany
Bern University of Applied Sciences
Goethe University; Maastricht University Medical Center; Swiss Federal Institute...

Completed

Application of Whole-body Vibration With Stochastic Resonance in Frail Elderly: The Effects on Postural Control

Equilibration Disorder, Vestibular Nerve

Switzerland
Bern University of Applied Sciences
Goethe University; Maastricht University Medical Center; Swiss Federal Institute...

Completed

Innovative Training Methods for Frail Elderly in the Training Gain Stage

Poor Performance Status

Switzerland
Bern University of Applied Sciences
Goethe University; Maastricht University Medical Center; Swiss Federal Institute...

Completed

Innovative Training Program for Elderly in Need of Care Individuals

Muscle Weakness | Poor Performance Status

Switzerland
Bern University of Applied Sciences
Goethe University; Maastricht University Medical Center; Swiss Federal Institute...

Completed

Effects of Whole-Body Vibration on Balance in the Elderly Population

Distorted; Balance
Goethe University
German Federal Ministry of Education and Research; Deutsche Krebshilfe e.V....

Completed

German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003)

Adult Acute Lymphocytic Leukemia

Germany
Johannes Vermehren
Robert Bosch Medical Center; Klinikum Stadt Hanau

Unknown

PTFE Stents for Treatment of Malignant Biliary Strictures

Bile Duct Cancer | Pancreas Cancer | Bile Duct Stricture

Germany
Peter Eickholz
Heidelberg University; Dr. August Wolff GmbH & Co. KG Arzneimittel; Gaba International...

Terminated

Effect of Postsurgical Systemic Doxycycline After Regenerative Periodontal Therapy (GTRDOXY)

Periodontitis

Germany
Johann Wolfgang Goethe University Hospital
CSL Behring; B. Braun Melsungen AG; Vifor Pharma; Fresenius Kabi

Recruiting

The German Patient Blood Management Network

Clinical Safety of a PBM Program

Germany
Dr. Frank Behrens
Johann Wolfgang Goethe University Hospital

Recruiting

Prevention of Paclitaxel-induced Neuropathic Pain in Patients With Planned Paclitaxel Chemotherapy (PrevTel) (PrevTel)

Neuropathic Pain | Chemotherapy Effect

Germany
Goethe University
Stichting Hemato-Oncologie voor Volwassenen Nederland; Polish Adult Leukemia... and other collaborators

Terminated

Panobinostat Maintenance After HSCT fo High-risk AML and MDS

Myelodysplastic Syndromes (MDS) | Acute Myeloid Leukaemia (AML)

Germany, Netherlands
University Hospital of Cologne
Albert Einstein College of Medicine; Monash University; The Alfred; Johann Wolfgang... and other collaborators

Not yet recruiting

PrognostICate- Study:Prognostication of ICU- and Ventilator- Days Over the Next Years Until 2040 (PrognostICate)

ICU Admission
Grete Andersen, MD

Completed

High Intensity Training in Patients With Facioscapulohumeral Muscular Dystrophy (HIT-FSHD)

FSHD - Facioscapulohumeral Muscular Dystrophy

Denmark

Clinical Trials Sponsored by Goethe University

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