Search clinical trials for: Adenosine A3 receptor antagonist

Total 41633 results

Breath of Life International Pharma Ltd

Completed

A Phase I Open Label Study to Assess PK and Safety of Plant Cannabis Extract

Healthy

Israel
University of Barcelona

Completed

Masticatory Side Change and Masticatory Function.

Chewing Problem | Mastication Disorder

Spain
Palobiofarma SL

Completed

"First-in-human" Study To Assess the Safety and Tolerability of PBF-677 in Healthy Volunteers

Glaucoma
Craig L Slingluff, Jr
GlaxoSmithKline

Completed

Study to Assess Safety and Immune Response of Stage IIB-IV Resected Melanoma After Treatment With MAGE-A3 ASCI (Mel55)

Melanoma

United States
AO Clinical Investigation and Publishing Documentation

Terminated

Spine FA3 - a Prospective, International, Multicenter Cohort Study on Treatment of of AO A3 Thoracolumbar Fractures (FA3)

Single Level Stable Thoracolumbar Fracture Type AO A3 | Multiple Level Stable Thoracolumbar Fracture Type AO A3

Brazil, Germany, Chile, Czechia, Italy, Portugal
Peking Union Medical College Hospital

Recruiting

Application of 68Ga-labeled ACE2 Targeting Probe PET/CT Imaging in Tracing ACE2 Expression and Diagnosis of Lung Cancer

Lung Cancer | Healthy Human

China
M.D. Anderson Cancer Center
GlaxoSmithKline

Completed

High-Dose Interleukin-2 (HDIL-2), Combined With recMAGE-A3 + AS15 ASCI

Melanoma

United States
University of Arkansas

Completed

Study of MAGE-A3 and NY-ESO-1 Immunotherapy in Combo With DTPACE Chemo and Auto Transplantation in Multiple Myeloma

Multiple Myeloma

United States
Canadian Cancer Trials Group
Ottawa Hospital Research Institute

Active, not recruiting

MG1 Maraba/MAGE-A3, With and Without Adenovirus Vaccine With Transgenic MAGE-A3 Insertion in Incurable MAGE-A3-Expressing Solid Tumours

Advanced/Metastatic Solid Tumours

Canada
Dentsply International

Withdrawn

A Descriptive, Prospective Clinical Study to Evaluate Full Dentures Fabricated by Additive Manufacturing

Mouth, Edentulous

United States
Neuromod Devices Ltd.
BRAI3N (clinical site), Belgium; St James's Hospital (clinical site), Ireland; German Hearing Center Hannover (clinical site), Germany and other collaborators

Completed

Treatment Evaluation of Neuromodulation for Tinnitus - Stage A3 (TENT-A3)

Tinnitus

Belgium, Germany, Ireland
Palobiofarma SL
Clínica Universidad de Navarra

Completed

Study to Assess the Safety and Tolerability of PBF-1650 in Healthy Volunteers. (ADENOIMMUNE)

Psoriasis

Spain
Institute of Regenerative and Cellular Medicine

Unknown

Safety and Clinical Effectiveness of A3 SVF in Osteoarthritis

Osteoarthritis

United States
GlaxoSmithKline

Completed

A Study to Test the Benefit of a New Anti-cancer Treatment in Patients With Unresectable Advanced Melanoma (PREDICT)

Melanoma

United States, Spain, Germany, France, Poland, Italy, Ireland, Russian Federation
GlaxoSmithKline

Completed

Study of GSK2132231A Antigen-Specific Cancer Immunotherapeutic in Patients With Inoperable Metastatic Cutaneous Melanoma

Melanoma

France, Belgium
Associação para o Desenvolvimento do Centro Académico...
European Regional Development Fund; Loulé Municipal Council; Albufeira Municipal... and other collaborators

Recruiting

Algarve Active Ageing - Cardiac and Osteoarthritis Rehabilitation (A3-COR) (A3-COR)

Hypertension | Osteoarthritis, Knee | Dyslipidemias | Type 2 Diabetes | Myocardial Infarction, Acute | Smoking Habit

Portugal
Tampere University
European Union; Academy of Finland; Cancer Society of Finland

Active, not recruiting

Effectiveness of Cervical Screening in HPV Vaccinated Women (HPV-004)

Cervical Intraepithelial Neoplasia Grade 2/3

Finland
University Hospital, Clermont-Ferrand
Stryker SA; Polyclinique du Parc Rambot

Completed

Metaphyseal Distal Radius Fractures

Metaphyseal Radius Fractures (AO Type A2, A3, C1 et C2)

France
Assiut University

Unknown

Role of Sorcin and Annexin A3 in Breast Cancer Patients

Breast Cancer
University of Maryland, Baltimore
National Institute of Dental and Craniofacial Research (NIDCR)

Completed

0804 GCC: MAGE-A3/HPV 16 Vaccine for Squamous Cell Carcinoma of the Head and Neck

Squamous Cell Carcinoma of the Head and Neck

United States
Patrice Jichlinski
GlaxoSmithKline; Ludwig Center for Cancer Research of Lausanne

Completed

BCG Modulation of the recMAGE-A3 + AS15 ASCI Response in the Treatment of Non Muscle Invasive Bladder Cancer (NMIBC) Patients

Bladder Cancer

Switzerland
European Association of Urology Research Foundation
GlaxoSmithKline

Terminated

Safety and Efficacy Study of MAGE-A3 + AS-15 in Patients With Muscle-invasive Bladder Cancer After Cystectomy (MAGNOLIA)

Urinary Bladder Neoplasms

France, Spain, Netherlands, Germany, Poland, Romania, Czechia, Italy, Russian Federation, Ukraine
National Cancer Institute (NCI)

Terminated

MAGE-A3/12 Metastatic Cancer Treatment With Anti-MAGE-A3/12 TCR-Gene Engineered Lymphocytes

Metastatic Cancer | Metastatic Melanoma | Metastatic Renal Cancer

United States
H. Lee Moffitt Cancer Center and Research Institute
GlaxoSmithKline; Oncovir, Inc.

Terminated

Phase II Study to Assess the Safety and Immunogenicity of recMAGE-A3+AS15 ASCI With or Without Poly IC:LC

Melanoma

United States
Ludwig Institute for Cancer Research
Memorial Sloan Kettering Cancer Center; Fox Chase Cancer Center; GlaxoSmithKline and other collaborators

Completed

MAGE-A3 Protein + AS15 as Consolidation for Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation

Multiple Myeloma

United States
Szu-Hua Pan
GlaxoSmithKline

Completed

The Correlation Between MAGE-A3, PRAME Polymorphism and Expression Levels of MAGE-A3 and PRAME in NSCLC Patients

Carcinoma, Non-Small-Cell Lung
GlaxoSmithKline

Terminated

MAGE-A3 Antigen-Specific Cancer Immunotherapeutic in Patients With Progressive Metastatic Cutaneous Melanoma

Melanoma

Norway, Argentina, Greece
Y Biologics Inc.
Novotech (Australia) Pty Limited

Active, not recruiting

Dose Escalation/Dose Expansion Study of YBL-006 in Patients With Advanced Solid Tumors

Advanced Solid Tumors

Korea, Republic of, Thailand, Australia
Novo Nordisk A/S

Completed

Safety and Tolerability of Insulin Degludec/Liraglutide (A3) in Healthy Subjects

Healthy | Diabetes

Germany
Penn State University

Withdrawn

A Vaccine Study for High Risk Cancers

Neuroblastoma | Osteogenic Sarcoma | Rhabdomyosarcoma
Mitsubishi Tanabe Pharma Corporation

Completed

Safety, Pharmacokinetics and Efficacy Study of MP-214 in Patients With Schizophrenia

Schizophrenia

Japan
Società Italiana Talassemie ed Emoglobinopatie
University of Palermo; University of Campania "Luigi Vanvitelli"; Fondazione... and other collaborators

Completed

Hepatitis C Virus Infection in Patients With Hemoglobinopathies

Hepatitis C, Chronic | Hemoglobinopathies
Assiut University

Not yet recruiting

Role of LILRA3 in Ankylosing Spondylitis and Axial Psoriatic Patients

Autoimmune Diseases
ProteoSys AG
Charite University, Berlin, Germany; Medical University Innsbruck; University... and other collaborators

Unknown

Annexin A3 (ANXA3) as Protein-Based Marker for Non-Invasive Molecular Diagnostics of Prostate Carcinoma

Benign Prostatic Hyperplasia | Prostate Cancer | Prostatic Intraepithelial Neoplasia
Memorial Sloan Kettering Cancer Center

Completed

CT7, MAGE-A3, and WT1 mRNA-electroporated Autologous Langerhans-type Dendritic Cells as Consolidation for Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation

Multiple Myeloma

United States
LMU Klinikum

Unknown

Operative Treatment of 2-fragment-fractures (AO 11-A3) of the Proximal Humerus in the Elderly: Cement Augmented Locking Plate Philos vs. Proximal Humerus Nail MultiLoc

Shoulder Fractures | Intramedullary | Bone Plates

Germany
Mitsubishi Tanabe Pharma Corporation
Vertex Pharmaceuticals Incorporated

Completed

Safety and PK Study of MP-424 to Treat Chronic Hepatitis C

Chronic Hepatitis C

Japan
GlaxoSmithKline

Terminated

A Study of Safety and Clinical Activity of Immunotherapy Plus Chemotherapy in Metastatic Melanoma Patients

Melanoma

Belgium, France
National Cancer Institute (NCI)

Completed

T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-DP0401 Positive

Melanoma | Cervical Cancer | Breast Cancer | Renal Cancer | Urothelial Cancer

United States
National Cancer Institute (NCI)

Terminated

T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-A*01 Positive

Melanoma | Cervical Cancer | Breast Cancer | Bladder Cancer | Renal Cancer

United States
Alexza Pharmaceuticals, Inc.

Completed

Staccato Apomorphine Multi-dose PK and PD in Patients With Parkinson's Disease

Parkinson's Disease

Netherlands
University Hospital, Toulouse

Completed

Impact of Anti-HLA Donor-specific Antibodies in ABO-incompatible Kidney Transplantation (A3)

Kidney Transplant

France
Cancer Research UK
Barinthus Biotherapeutics

Suspended

A Trial of ChAdOx1 and MVA Vaccines Against MAGE-A3 and NY-ESO-1

Esophageal Neoplasms | Non-small Cell Lung Cancer (NSCLC)

United Kingdom
China Medical University, China
Shanghai First Song Therapeutics Co., Ltd

Recruiting

An Exploratory Clinical Study Evaluating the Safety and Efficacy of Anti-CEA-CAR-T Cells Injection in Patients With CEA+ Locally Advanced and/or Metastatic Solid Tumors

Carcinoma

China
AO Innovation Translation Center
AO Foundation, AO Spine

Completed

Thoracolumbar Burst Fractures Study Comparing Surgical Versus Non-surgical Treatment

Thoracolumbar Burst Fracture

United States, Egypt, Australia, Canada, Greece, India, Netherlands, Romania, Spain, Switzerland
University Hospital Tuebingen

Completed

Herbal-Based Medication vs. Placebo in Preventing Acute Otitis Media in Children at High Risk of Recurrence (OTV_PRE_01)

Acute Otitis Media

Germany
Fudan University

Unknown

Role of Huachansu in Treating Hepatocellular Carcinoma and the Correlation With Na+/K+-ATPase

Carcinoma, Hepatocellular

China
Washington University School of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Genetic Regulation of Surfactant Deficiency

Respiratory Distress Syndrome, Newborn

United States
Centre Hospitalier Universitaire Vaudois
Immutep S.A.S.

Terminated

Immunotherapy of HLA-A2 Positive Stage II-IV Melanoma Patients (LAG-3/IMP321)

Melanoma

Switzerland
Seoul National University Hospital
GlaxoSmithKline

Suspended

Tumor Markers Study in Gastric Cancer for Cancer Immunotherapy (ONCO-RD 010 CRT) (ONCO-RD010CRT)

Stomach Neoplasms

Search clinical trials for: Adenosine A3 receptor antagonist

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