Search clinical trials for: Central analgesic effect

Total 202129 results

Ottawa Hospital Research Institute

Not yet recruiting

Prehospital Analgesia in Adults Using Inhaled Methoxyflurane Study

Pain, Acute
Jagiellonian University

Recruiting

Opioid-free Anesthesia, Optimization of Anesthesia After Bariatric Surgery

Analgesics, Opioid | Anesthesia; Adverse Effect

Poland
University of Virginia

Not yet recruiting

Pain Control and Quality of Recovery After Intravenous Methadone Versus Intrathecal Morphine in Major Abdominal Surgery

Pain, Postoperative

United States
University of Padova

Not yet recruiting

Effects of Sufentanil Target Controlled Infusion on Patient State Index Values and Electroencephalographic Spectrum During Total Intravenous Anesthesia With Propofol

Target Controlled Infusion | Sufentanil | Anesthesia Brain Monitor

Italy
Hospital Universiti Sains Malaysia

Not yet recruiting

Different Doses of Intravenous Administered Dexamethasone Effecting Brachial Plexus Supraclavicular Block

End Stage Renal Failure
Aswan University

Recruiting

Systemic Versus Local Dexmedetomidine as An Adjuvant to Bupivacaine in Ultrasound Guided Erector Spinae Block

Dexmedetomidine | Erector Spinae Block

Egypt
Tongji Hospital

Not yet recruiting

Effect of Amobarbital Sodium Combined With Low-dose Propofol on Hemodynamics During Induction and Perioperative Adverse Reactions

Hemodynamics Instability | Amobarbital Sodium
Aswan University

Recruiting

Fentanyl Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Spinal Anesthesia ; Peritoneal Symptomatic Effects

Dexmedetomidine | Fentanyl

Egypt
Konya City Hospital

Not yet recruiting

Suprainguinal Fascia Iliaca Block in Knee Arthroplasty

Analgesia | Anesthesia, Local
London Health Sciences Centre
Western University

Not yet recruiting

Use of 81 vs 325mg of ASA in Treatment of BCVI

Carotid Artery Injuries | Traumatic Injury | Vertebral Artery Injury
Murdoch Childrens Research Institute

Not yet recruiting

A Study Investigating the Change in Metabolism Phenotype in Paediatric, Adolescent & Young Adults With Hodgkin or Non-Hodgkin Lymphoma. (PEGASUS)

Hodgkin Lymphoma | Non Hodgkin Lymphoma

Australia
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

A Study to Evaluate Pregabalin in Painful Diabetic Peripheral Neuropathy

Painful Diabetic Neuropathy
University Hospital, Tours

Not yet recruiting

Efficacy of EMONO as an add-on Therapy to Conventional Antidepressants for the Treatment of Depressive Symptoms in Nursing-home Residents With Neurocognitive Disorders: a Randomized Controlled Trial- (PROTO-EHPAD)

Depression | Neurocognitive Disorders
Centre Hospitalier Universitaire, Amiens
University Hospital, Rouen; University Hospital, Lille

Recruiting

Non-steroidal Anti-inflammatory in Cardiac Surgery (KETOPAIN)

Cardiac Surgery | Acute Postoperative Pain | Pain Intensity | Multimodal Pain Management | Non-steroidal Anti-inflammatory Drugs

France
Primus Pharmaceuticals
Sun Valley Arthritis Center

Recruiting

Effect of Metaxalone 640 mg (M640) on Truck Driving Ability and Cognition Compared to Other Skeletal Muscle Relaxants

Cognitive Impairment

United States
Indonesia University

Not yet recruiting

Opioid Free Versus Opioid Balanced Anesthesia in Ophthalmic Surgery

Anesthesia and Analgesia | Anesthesia, Endotracheal
Northwell Health

Recruiting

Impact of Preoperative Opioid-free Multimodal Analgesia on Time to Trial of Void in Ambulatory Urogynecologic Surgeries

Pain, Postoperative | Postoperative Pain, Acute

United States
Jagiellonian University

Recruiting

Opioid-free Anesthesia as an Alternative to General Anesthesia in Abdominal Surgery

Anesthesia, General | Analgesics, Opioid | Anesthesia, Endotracheal

Poland
Johns Hopkins University
National Institutes of Health (NIH)

Not yet recruiting

Behavioral Pharmacology of Orally Administered THC and D-limonene

THC | Subjective Drug Effects | D-limonene

United States
University of Novi Sad

Recruiting

Intraoperative Dexmedetomidine and Coronary Artery Bypass Graft Surgery

Acute Kidney Injury

Serbia
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Rapid Outpatient Low-dose Initiation of Buprenorphine for OUD With Fentanyl Use (ROLDI)

Opioid Use Disorder
University of Wisconsin, Madison

Not yet recruiting

Ketamine-assisted Psychotherapy for Adolescent PTSD (KAP)

Posttraumatic Stress Disorder

United States
Aurora Health Care

Not yet recruiting

Comparing Magnesium 2g Versus 4g Versus Placebo in the Incidence of Treating AFF RVR (ATRIUM)

Atrial Fibrillation | Tachycardia Atrial | Atrial Flutter With Rapid Ventricular Response

United States
Cairo University
Theodor Bilharz Research Institute

Not yet recruiting

Analgesic Effect of Melatonin and Vitamin C Administration, Alone or In Combination in Major Abdominal Surgery.

Postoperative Pain

Egypt
The University of Texas Health Science Center,...

Not yet recruiting

Study of Injectable Naltrexone and Oral Bupropion Among Cigarette Smokers With Schizophrenia

Smoking Cessation

United States
The Cleveland Clinic

Not yet recruiting

NonNarcotic Pain Control in Percutaneous Needle Tenotomy of Elbow

Chronic Pain | Elbow Pain

United States
Kasr El Aini Hospital

Recruiting

Evaluation of Lidocaine Spray Versus Dexmetomidine Spray on Stress Response

To Measure Systolic Blood Pressure Postintubation

Egypt
State University of New York - Upstate Medical...

Not yet recruiting

Intranasal Dexmedetomidine vs. Standard of Care for Emergency Department (ED) Procedural Sedation in the Older Adult

Altered Mental Status
Eli Lilly and Company

Not yet recruiting

A Drug-Drug Interaction (DDI) Study of Orforglipron With Carbamazepine in Healthy Participants

Healthy

United States
Algemeen Ziekenhuis Maria Middelares

Not yet recruiting

Interpectoral-pectoserratus Plane Block for Minimally Invasive Aortic Valve Replacement Via Right Anterior Minithoracotomy (PAINCARE)

Analgesic Effect

Belgium
Dr Abdurrahman Yurtaslan Ankara Oncology Training...

Not yet recruiting

The Effectiveness of Bupivacaine and Bupivacaine+Dexmedetomidine Combination in Transversus Abdominis Plane* Block (TAP)

Colorectal Neoplasms | Colorectal Cancer

Turkey
Sanofi

Recruiting

A Study to Investigate Long-term Safety and Tolerability of Tolebrutinib in Participants With Multiple Sclerosis.

Relapsing Multiple Sclerosis | Secondary Progressive Multiple Sclerosis | Progressive Relapsing Multiple Sclerosis

Belgium
Al-Azhar University

Not yet recruiting

the Impact of Ketamine Gargling on the Incidence of Post Intubation Sore Throat

Postoperative Sore Throat

Iraq
Jessica Merlin
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Pain Self-Management and Patient-Oriented Dosing for Pain and in Retention Opioid Treatment (TREETOP)

Chronic Pain | Opioid Use Disorder

United States
Brigham and Women's Hospital
Open Medicine Foundation

Not yet recruiting

LIFT: Life Improvement Trial (LIFT)

ME/CFS
Assiut University

Not yet recruiting

Effect of Intrathecal Magnesium Sulfate Versus Intravenous Magnesium Sulfate on Postoperative Pain After Abdominal Hysterectomy

Abdominal Hysterectomy
The Catholic University of Korea
Viatris Korea

Not yet recruiting

The Effect of Pregabalin on Shoulder Pain of Patients With Central Sensitization Who Undergo Arthroscopic Rotator Cuff Repair

Neuropathic Pain | Rotator Cuff Tears | Central Sensitisation
Alexandria University

Not yet recruiting

Propofol or Benzodiazepine Combined With Ketamine for Procedural Sedation in Emergency Setting

Procedural Sedation
Beni-Suef University

Recruiting

The Sedative Effects of Dexmedetomidine VS Propofol During Peribulbar Anesthesia in Patients Undergoing Vitrectomy Surgery

Satisfaction | Patient

Egypt
Tongji Hospital

Not yet recruiting

Opioid-Free Combined Anesthesia With Spontaneous Breathing for VATS

Video-assisted Thoracoscopic Lung Surgery；Anesthesia
Tribhuvan University Teaching Hospital, Institute...

Not yet recruiting

Comparison Between Hyperbaric Bupivacaine With Fentanyl vs. Hyperbaric Bupivacaine With Dexmedetomidine in Reducing Visceral Pain During Cesarean Delivery Under Spinal Anaesthesia

Visceral Pain
Cessatech A/S

Not yet recruiting

Safety, Tolerability, Analgesic Effect, and Feasibility of Intranasal CT001 in Pediatric Patients

Pain
Minia University Hospital

Recruiting

Dexmedetomidine on Postoperative Cognitive Dysfunction and Serum Tau-217 Protein.

Cognitive Impairment

Egypt
Children's Hospital of Eastern Ontario

Recruiting

Study of IV Ketamine for Emergency Department Treatment of Adolescent Suicidal Ideation (KSI)

Suicidal Ideation | Suicidal Ideas

Canada
Antonios Likourezos

Not yet recruiting

Nebulized Ketamine to Nebulized Fentanyl for Treating Acute Painful Conditions in the ED (KETAFEN)

Pain, Acute
Tanta University

Not yet recruiting

Different Doses of Dexmedetomidine in External Oblique Intercostal Plane Block in Splenectomy

Dexmedetomidine | Splenectomy | External Oblique Intercostal Plane Block

Egypt
Ain Shams University

Recruiting

Analgesic Effect of Illiohypogastic & Ilioinguinal Nerve Block in TAVR - TF (Prospective Randomized Study)

Anesthesia, Local

Egypt
Assiut University

Not yet recruiting

Suprazygomatic Nerve Block in Tonsillectomy Patients

Tonsillectomy
Kafrelsheikh University

Recruiting

Zonisamide Versus Propranolol in Migraine

Migraine

Egypt
Postgraduate Institute of Dental Sciences Rohtak

Not yet recruiting

Pregabalin as an add-on Therapy to Carbamazepine in Trigeminal Neuralgia Patients

Trigeminal Neuralgia

India

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